A one-line profiler: Simply add "import profiler" to your script

profiler.py

import cProfile
import inspect
import sys

# Ensure that we aren't being run directly
if __name__ != "__main__":
    caller = None
    
    # Look for the first actual .py filename
    for frame in inspect.stack()[1:]:
        if not frame.filename.startswith("<"):
            caller = frame.filename
            break
    # Set some important global variables
    globals = {
        "__file__": caller,
        "__name__": "__main__",
        "__package__": None,
        "__cached__": None,
    }
    
    # Read the script that imported us into memory
    with open(caller, "r") as tmp:
        # Remove the line that imported us to prevent a loop
        caller_rewritten = tmp.read().replace("import profiler", "")
        code = compile(caller_rewritten, caller, "exec")
    try:
        cProfile.runctx(code, globals, None)
        sys.exit(0)
    except BrokenPipeError as exc:
        sys.stdout = None
        sys.exit(exc.errno)