NodeJs + Nginx

nginx.conf

upstream node {
    server 127.0.0.1:3000;
}
 
server {
    listen 80;
    server_name yoursite.com;
    root /path/to/node/app/public;

    location / {
        try_files $uri $uri/ @node;
    }

    location @node {
        proxy_set_header X-Real-IP $remote_addr;
        proxy_set_header X-Forwarded-For $proxy_add_x_forwarded_for;
        proxy_set_header Host $http_host;
         
        proxy_pass http://node;
        proxy_redirect off;
  
        proxy_http_version 1.1;
        proxy_set_header Upgrade $http_upgrade;
        proxy_set_header Connection "upgrade";
    }
 }

upstream node {
    server 127.0.0.1:3000;
}

Replace :3000 to your node application port.