gistfile1.rb

require 'rubygems'
require 'bio'

seq = Bio::Sequence::NA.new("atgcagctctttgtccgcgcccaggagctacacaccttcgaggtgaccggccaggaaacggtcgcccagatcaaggctcatgtagcctcactggagggcattgccccggaagatcaagtcgtgctcctggcaggcgcgcccctggaggatgaggccactctgggccagtgcggggtggaggccctgactaccctggaagtagcaggccgcatgcttggaggtaaagtccatggttccctggcccgtgctggaaaagtgagaggtcagactcctaaggtggccaaacaggagaagaagaagaagaagacaggtcgggctaagcggcggatgcagtacaaccggcgctttgtcaacgttgtgcccacctttggcaagaagaagggccccaatgccaactcttaa")

remote = Bio::Blast.remote('blastn', 'genes-nt', '-e 0.01')
blobj = remote.query(seq)
blobj.each_hit do |hit|
  puts "#{hit.target_def} #{hit.evalue}"
end