Last active
August 29, 2015 14:20
-
-
Save pducrot/a26ab73f4bf49574ab38 to your computer and use it in GitHub Desktop.
Compound Structure Network
This file contains bidirectional Unicode text that may be interpreted or compiled differently than what appears below. To review, open the file in an editor that reveals hidden Unicode characters.
Learn more about bidirectional Unicode characters
| CID IC50 Target pIC50 | |
| CID0300385 2.341 JNK3 5.63 | |
| CID0588806 5.959 JNK3 5.22 | |
| CID0649913 6.628 JNK3 5.18 | |
| CID0651058 4.217 JNK3 5.37 | |
| CID0651323 3.136 JNK3 5.50 | |
| CID0658703 3.962 JNK3 5.40 | |
| CID0658795 8.417 JNK3 5.07 | |
| CID0660128 6.827 JNK3 5.17 | |
| CID0661045 6.677 JNK3 5.18 | |
| CID0661441 4.873 JNK3 5.31 | |
| CID0793991 9.841 JNK3 5.01 | |
| CID0796100 6.935 JNK3 5.16 | |
| CID0979869 1.505 JNK3 5.82 | |
| CID1045996 4.261 JNK3 5.37 | |
| CID1087003 9.247 JNK3 5.03 | |
| CID1245872 4.535 JNK3 5.34 | |
| CID1288597 .809 JNK3 6.09 | |
| CID1294440 6.331 JNK3 5.20 | |
| CID2091134 5.942 JNK3 5.23 | |
| CID2099071 .401 JNK3 6.40 | |
| CID2377706 6.771 JNK3 5.17 | |
| CID2501747 8.827 JNK3 5.05 | |
| CID2575371 7.19 JNK3 5.14 | |
| CID2589475 7.93 JNK3 5.10 | |
| CID2953401 9.757 JNK3 5.01 | |
| CID2962251 7.366 JNK3 5.13 | |
| CID2971411 2.619 JNK3 5.58 | |
| CID2972189 1.819 JNK3 5.74 | |
| CID2974150 6.263 JNK3 5.20 | |
| CID3236317 6.931 JNK3 5.16 | |
| CID3236465 7.159 JNK3 5.15 | |
| CID3238045 1.819 JNK3 5.74 | |
| CID3238372 7.969 JNK3 5.10 | |
| CID3239708 4.189 JNK3 5.38 | |
| CID3240660 1.892 JNK3 5.72 | |
| CID3240978 7.984 JNK3 5.10 | |
| CID3241191 7.873 JNK3 5.10 | |
| CID3241493 4.604 JNK3 5.34 | |
| CID3242057 3.356 JNK3 5.47 | |
| CID3242510 9.211 JNK3 5.04 | |
| CID3242979 2.023 JNK3 5.69 | |
| CID3243409 7.928 JNK3 5.10 | |
| CID3243453 4.058 JNK3 5.39 | |
| CID3243778 5.004 JNK3 5.30 | |
| CID3349764 9.896 JNK3 5.00 | |
| CID4907320 .502 JNK3 6.30 | |
| CID5144290 6.203 JNK3 5.21 | |
| CID5309978 5.46 JNK3 5.26 | |
| CID5310086 9.148 JNK3 5.04 | |
| CID5310693 2.164 JNK3 5.66 | |
| CID5389994 6.691 JNK3 5.17 | |
| CID6398908 8.813 JNK3 5.05 |
This file contains bidirectional Unicode text that may be interpreted or compiled differently than what appears below. To review, open the file in an editor that reveals hidden Unicode characters.
Learn more about bidirectional Unicode characters
| Hashkey Smiles | |
| 88e8d646a409a3a47522d520919494fb [R]c1n[nH]c2ccccc12 | |
| 65093ae6ad910dc5d2bfcca22b047a91 [R]CCSc1nc(C)nc2ccccc12 | |
| edafbcf9eb5a81147fd9dc796993b713 [R]C(=O)O.[R]c1nc(C)nc2ccccc12 | |
| 78e1cbc68f41a453f1787d2e7ea1ff91 [R]c1nc(C)nc2ccccc12 | |
| c6d9a93bad85b7b17d899129f4f2a4c1 [R]Sc1nc(C)nc2ccccc12 | |
| ee0eaeafc191199b3d61a9f8cc9e4667 [R]CC.[R]c1ccccc1NC(=O)CSc2ncc(C(=O)OCC)c(N)n2 | |
| ecaedcc6503e4786f981123e996a4bd2 [R]CC.[R]c1cnc(SCC(=O)Nc2ccccc2C(=O)OCC)nc1N | |
| ba3a3ff720459724dec665dbc26523c0 [R]CSc1ncc(C(=O)OCC)c(N)n1.[R]c2ccccc2C(=O)OCC | |
| 0b057900281846b77374ec9f863b365d [R]SCC(=O)Nc1ccccc1C(=O)OCC.[R]C(=O)OCC | |
| c6dd30557c6ae093d154bd0a787743c0 [R]NC(=O)CSc1ncc(C(=O)OCC)c(N)n1.[R]C(=O)OCC | |
| c6bfc33ab263f2fb82df21e0ae2a229b [R]c1ncc(C(=O)OCC)c(N)n1.[R]c2ccccc2C(=O)OCC | |
| 65dd0c693fca0b0908d38dd14a186bf7 [R]c1ccccc1NC(=O)CSc2ncc(C(=O)OCC)c(N)n2 | |
| 66f54a0fe31e42dbf8bc2fcf84829d9c [R]c1cnc(SCC(=O)Nc2ccccc2C(=O)OCC)nc1N | |
| 8cae087819c9fb28d6882ab6bb4bc28f [R]Sc1ncc(C(=O)OCC)c(N)n1.[R]c2ccccc2C(=O)OCC | |
| a959cb036fb9e9b90d54319117d75839 [R]CC(=O)Nc1ccccc1C(=O)OCC.[R]C(=O)OCC | |
| eedc196b125e908258cdb04c84d66941 [R]CC.[R]CC(=O)Nc1ccccc1C(=O)OCC | |
| c551af1b2e3ef66e4db999881f99be04 [R]CC.[R]C(=O)Nc1ccccc1C(=O)OCC | |
| cd6c2e62f31991b8dbe1483e107d41ff [R]C(=O)Nc1ccccc1C(=O)OCC.[R]C(=O)OCC | |
| a43baab250aa7c8f81a1f0d0c2c3834e [R]C(=O)OCC.[R]c1ccccc1C(=O)OCC | |
| 2c9ee8020069ef335094681ba3f14e9d [R]C(=O)OCC.[R]c1ncc(C(=O)OCC)c(N)n1 | |
| 07ce6d1122153927dff02ed60732b6d9 [R]CC.[R]NC(=O)CSc1ncc(C(=O)OCC)c(N)n1 | |
| bfbdf7b7b31f7c324bee053b178fa549 [R]CC.[R]CSc1ncc(C(=O)OCC)c(N)n1 | |
| f79fb5c648fc7adf05ef08d75b55c7e9 [R]NC(=O)CSc1ncc(C(=O)OCC)c(N)n1 | |
| aa79e096ed4cadb9e179a049fe80f1ad [R]CC.[R]SCC(=O)Nc1ccccc1C(=O)OCC | |
| b44b7a64c33c041db9903c4ae108d185 [R]SCC(=O)Nc1ccccc1C(=O)OCC | |
| 6b24579b9d675215d1e1a5f09e4ecedd [R]CSc1ncc(C(=O)OCC)c(N)n1.[R]C(=O)OCC | |
| 588231cef0d378a1a31b038a466954a2 [R]Sc1ncc(C(=O)OCC)c(N)n1.[R]C(=O)OCC | |
| a6953a8e72fb3dca47763fa8fa3e5811 [R]C1CCN(CC(=O)Nc2ccccc2C(=O)OC)CC1.[R]c3ccccc3C | |
| a84e97cafab1aff9e3818dfd35e78074 [R]CN1CCC(CC1)NC(=O)c2ccccc2C.[R]c3ccccc3C(=O)OC | |
| 711c85af99f5f16c1110341c555469ea [R]c1ccccc1NC(=O)CN2CCC(CC2)NC(=O)c3ccccc3C | |
| 267625b560a4f73a56ceda9a9485074d [R]CC(=O)Nc1ccccc1C(=O)OC.[R]NC(=O)c2ccccc2C | |
| 500dce1259c314c9ed41233739b499c8 [R]C(=O)NC1CCN(CC(=O)Nc2ccccc2C(=O)OC)CC1 | |
| 1502c8559c1b824a74ec5c9b649294a1 [R]NC(=O)CN1CCC(CC1)NC(=O)c2ccccc2C.[R]C(=O)OC | |
| 69102fcea1fe2498d2308e4eefd95aa4 [R]N1CCC(CC1)NC(=O)c2ccccc2C.[R]c3ccccc3C(=O)OC | |
| f501991cfa0d12c3c155b1aad7eb1657 [R]CC(=O)Nc1ccccc1C(=O)OC.[R]c2ccccc2C | |
| a6d6785ede665e41d6c50e8c362325de [R]C(=O)Nc1ccccc1C(=O)OC.[R]c2ccccc2C | |
| d78623bbf0b40377d3a086e964fe5482 [R]C1CCN(CC(=O)Nc2ccccc2C(=O)OC)CC1 | |
| 3c83f145ab617751fc3fe970937e5103 [R]NC(=O)c1ccccc1C.[R]c2ccccc2C(=O)OC | |
| 858188041bdcb1c44fb2043541a2d0c3 [R]N1CCC(CC1)NC(=O)c2ccccc2C.[R]C(=O)OC | |
| 3c82d44ce8e5c697a54d7bd13377a28e [R]CN1CCC(CC1)NC(=O)c2ccccc2C.[R]C(=O)OC | |
| 5eb8ad9bd2adbd35a01df7efa3b33303 [R]NC(=O)CN1CCC(CC1)NC(=O)c2ccccc2C | |
| c28452affd8950fe9ff1a82b4dac3f2f [R]NC(=O)c1ccccc1C.[R]C(=O)Nc2ccccc2C(=O)OC | |
| ae60defdb373cec7c847c85910056891 [R]CN1CCC(CC1)NC(=O)c2ccc(C)cc2.[R]c3ccccc3C(=O)OC | |
| e275df06d312401d55e6b6cbc52dfbd8 [R]C1CCN(CC(=O)Nc2ccccc2C(=O)OC)CC1.[R]c3ccc(C)cc3 | |
| 8c4999a4bcb8e099d851b9377a69e214 [R]c1ccccc1NC(=O)CN2CCC(CC2)NC(=O)c3ccc(C)cc3 | |
| b24037a65d1abef0425306bb97608e26 [R]CC(=O)Nc1ccccc1C(=O)OC.[R]NC(=O)c2ccc(C)cc2 | |
| 59c1196c874be017ca0d639baac66919 [R]NC(=O)CN1CCC(CC1)NC(=O)c2ccc(C)cc2.[R]C(=O)OC | |
| 4fec4c8b530c2ceafaa8786afb54180d [R]N1CCC(CC1)NC(=O)c2ccc(C)cc2.[R]c3ccccc3C(=O)OC | |
| 0f0f6e9b582f9e348b0d549b16de67e6 [R]NC(=O)c1ccc(C)cc1.[R]c2ccccc2C(=O)OC | |
| 8c648457889c8cddacffc3722fce3647 [R]N1CCC(CC1)NC(=O)c2ccc(C)cc2.[R]C(=O)OC | |
| 720f1ca5c390832fbe1cbcca46a04c8a [R]CN1CCC(CC1)NC(=O)c2ccc(C)cc2.[R]C(=O)OC | |
| 7c604e61f6ca1595951320edf1aab8d3 [R]CC(=O)Nc1ccccc1C(=O)OC.[R]c2ccc(C)cc2 | |
| e2dc435ed98a790030751d5825df7fc2 [R]C(=O)Nc1ccccc1C(=O)OC.[R]c2ccc(C)cc2 | |
| e03c59d086ff4381a852e328479ec1f8 [R]NC(=O)CN1CCC(CC1)NC(=O)c2ccc(C)cc2 | |
| ca14e92b04e32e1687ea3a00386d195c [R]NC(=O)c1ccc(C)cc1.[R]C(=O)Nc2ccccc2C(=O)OC | |
| 2527c4b7eff04857a9793417b511f0d7 [R]NCc1ccccc1.[R]NCc2cccnc2.[R]C#N | |
| 10968916cee9e1465dfdf4689b4a86f5 [R]CNc1nccc(NCc2ccccc2)c1C#N | |
| a3fdf8a3a08d78a6d1b1181853b1f552 [R]CNc1ccnc(NCc2cccnc2)c1C#N | |
| 473c69887f8dd4431bfd30aa13fab55e [R]Cc1ccccc1.[R]NCc2cccnc2.[R]C#N | |
| 987e85b799c4a879ccb9008aa8a54c65 [R]Cc1ccccc1.[R]Cc2cccnc2.[R]C#N | |
| 87acf50911b12485147fd05d63b43bce [R]Cc1ccccc1.[R]Cc2cccnc2 | |
| 9aa6ab5a736a785e11da50e6fed1a217 [R]Cc1cccnc1.[R]c2ccccc2 | |
| 2006eea01aa4cf20431502be4ab5bcd1 [R]Cc1ccccc1.[R]c2cccnc2 | |
| 89e0e9ebe03d639852af16bd27679b19 [R]Cc1cccnc1.[R]C#N.[R]c2ccccc2 | |
| d1a1fc377d285a5b94c2892fba071fa5 [R]C#N.[R]c1ccccc1.[R]c2cccnc2 | |
| 5eb100b0715eb3f91a6d67b2ea40eb06 [R]Cc1ccccc1.[R]C#N.[R]c2cccnc2 | |
| 83efb1f127fbaf179321564bbea7faa0 [R]Cc1ccccc1.[R]NCc2cccnc2 | |
| cc9cfd82792b809b2e990f0bcf8935ae [R]NCc1cccnc1.[R]c2ccccc2 | |
| aebc19065b10628d90410591752f5ecb [R]NCc1cccnc1.[R]C#N.[R]c2ccccc2 | |
| 10425f9a81c93ca64ebd8458312fda5f [R]c1ccnc(NCc2cccnc2)c1C#N | |
| ef4ce42f322cd50c929585a2122886e3 [R]Cc1cccnc1.[R]NCc2ccccc2.[R]C#N | |
| a746a5a65eff9269a9f9e56613873d08 [R]Cc1cccnc1.[R]NCc2ccccc2 | |
| 619e5e0582a86496e2e72e58832c77e2 [R]NCc1ccccc1.[R]c2cccnc2 | |
| 057de0c876de3b8cd831dbc8b4e02c48 [R]NCc1ccccc1.[R]C#N.[R]c2cccnc2 | |
| bfbbdaa5dc82adbeb14ee5ffbbe1265c [R]c1nccc(NCc2ccccc2)c1C#N | |
| 127cf3a9e42fe0a732399c1759f6c0ca [R]NCc1ccccc1.[R]NCc2cccnc2 | |
| acb75e79bf9d84d7d2a22fa831d7894d [R]Nc1nccc(NCc2ccccc2)c1C#N | |
| 2dbe13dcd4d3e5349e6ea010203c4874 [R]Nc1ccnc(NCc2cccnc2)c1C#N | |
| 0d0b23577e916d801b16c79ee41cc7a9 [R]\C(=C(\C)/NCc1ccc(OC)c(OC)c1)\C#N | |
| 9b507d773616c554f110c2505e8f9a4a [R]CN\C(=C(\C#N)/C(=O)N)\C.[R]OC.[R]OC | |
| 1e680a0ff1321991fd91e27643a63e94 [R]NCc1ccc(OC)c(OC)c1.NC(=O)[R][R]#N | |
| ad4414c1a078abd4479bf507a92c72db [R]NCc1ccc(OC)c(OC)c1.[R]C#N | |
| fa956cf48e421f6d6f327ecee19f7b28 [R]Cc1ccc(OC)c(OC)c1.[R]C#N | |
| d923c497ad6fa2bfb97bee8785cc2f36 [R]Cc1ccc(OC)c(OC)c1 | |
| be5f91ea90f5459cc32e7dc5d4b930a1 [R]C#N.[R]c1ccc(OC)c(OC)c1 | |
| b1dd3e6cfc911d4d68ae67959c041d2d [R]NCc1ccc(OC)c(OC)c1 | |
| 86d4ff5dc8c4a24fe1c4a656a3e41253 [R]c1ccc(OC)c(OC)c1.NC(=O)[R][R]#N | |
| c9d941555a21daea99473ca7dbf823a4 [R]C(=O)N.[R]c1ccc(OC)c(OC)c1 | |
| f3720625b84547fa0342130d71c222fa [R]Cc1ccc(OC)c(OC)c1.NC(=O)[R][R]#N | |
| 8424993d41bba2426a96b2cea90fe2cc [R]Cc1ccc(OC)c(OC)c1.[R]C(=O)N | |
| 01e71173afd3a4a95e745605a73dd3c3 [R]NCc1ccc(OC)c(OC)c1.[R]C(=O)N | |
| 454bce6e68642781b450a56943ddf3b4 [R]CN\C(=C(\C#N)/C(=O)N)\C.[R]OC | |
| d556d2e4152732d93bf9ac12147f9706 [R]N\C(=C(\C#N)/C(=O)N)\C.[R]OC | |
| b0bf920d09f64b72b6706b586504b044 [R]\C(=C(\C#N)/C(=O)N)\C.CO[R]=[R]OC | |
| e2b60e73b488be63f1b8f776fd054120 [R]N\C(=C(\C#N)/C(=O)N)\C.CO[R]=[R]OC | |
| dc51fb3fcd0bd0b2d95dfe4a981fc0e7 [R]Cc1ccc2OCOc2c1.[R]C(=O)OC | |
| c745e37b63771e4383d17aa77e7022dd [R]CN1C=C(C=C(Br)C1=O)C(=O)OC | |
| 29bf41103309565e679bc2ab97128ce3 [R]C1=CN(Cc2ccc3OCOc3c2)C(=O)C(=C1)Br | |
| 1495331ad0106b916b8b8c0a3788a710 [R]C(=O)OC.[R]c1ccc2OCOc2c1 | |
| a900d992cb492dfc9dbb61c30176db41 [R]N1C=C(C=C(Br)C1=O)C(=O)OC | |
| 085320c276a442f1ef9427ea87b6faa3 [R]Cc1ccc(OC)c(OC)c1.[R]C(=O)OC | |
| cb9a1fb61bda597e7139be60c3b18f3b [R]C1=CN(Cc2ccc(OC)c(OC)c2)C(=O)C(=C1)Br | |
| 4f91a4547dbadfbea7cf4d78cae1b7f4 [R]CN1C=C(C=C(Br)C1=O)C(=O)OC.[R]OC.[R]OC | |
| fe0613ccacb17f06765e38e8d608c2df [R]C(=O)OC.[R]c1ccc(OC)c(OC)c1 | |
| fa59b9d59fb82a2e459900ce86c52d24 [R]CN1C=C(C=C(Br)C1=O)C(=O)OC.[R]OC | |
| fc4e0abd68602694c8b19ef87dcbd5b4 [R]OC.[R]N1C=C(C=C(Br)C1=O)C(=O)OC | |
| 2e00652eb5da8368e0976d31bcdfa6f5 [R]OC.[R]OC.[R]N1C=C(C=C(Br)C1=O)C(=O)OC | |
| 5d2785e533e2b6377010a36f99f51e47 [R]C(C)Sc1ccc2ccccc2n1 | |
| 5fa63d8fb698f530e2ea89628ba2c5d6 [R]C(=O)O.[R]c1ccc2ccccc2n1 | |
| 6f3def4c2e7fb719304cbe206e52e58d [R]c1ccc2ccccc2n1 | |
| 4ae3a11a86d155839f705a26fffe9279 [R]Sc1ccc2ccccc2n1 | |
| c466584cb7d1962aa8c7a0bc12a0025f [R]N1C=CC(=C2C(=O)c3ccccc3C2=O)C=C1 | |
| c5093c27fd30d4dc0de9acb348a24e05 [R]Nc1cc(ncn1)n2cccn2 | |
| e044e3a6e910a817a50d0e90c2d1fd48 [R]c1cc(Nc2cccc(F)c2)ncn1 | |
| 64a2b3c4b9e8f319f9d09e9dec19b3bb [R]Nc1cccc(F)c1.[R]n2cccn2 | |
| 26d79097b5f6d4bdd0c848c774aebb87 [R]c1cc(ncn1)n2cccn2 | |
| 1beeb2ce47a17ec324ba579a923d924e [R]c1cccc(F)c1.[R]n2cccn2 | |
| 1b05049a0af94bed6451626462b3846d [R]C(=O)Nc1cccc(Cl)c1N2CCN(CC)CC2 | |
| 472db4d474003dfe2ad03f7292933197 [R]NC(=O)c1oc(Br)cc1.[R]N2CCN(CC)CC2 | |
| 0e66147fe6135c520f79772a1b7ab340 [R]c1oc(Br)cc1.[R]c2cccc(Cl)c2N3CCN(CC)CC3 | |
| 881f05a5341d275e18645b44c4a7cc4d [R]CC.[R]c1c(Cl)cccc1NC(=O)c2oc(Br)cc2 | |
| 86a238bc5d11f0aca92033eab613fcc7 [R]c1cccc(Cl)c1N2CCN(CC)CC2 | |
| e49d9343ccb5c43319f1d3970d0259ab [R]N1CCN(CC)CC1.[R]c2oc(Br)cc2 | |
| 28950805ac3a423e63b348603758b7d7 [R]c1c(Cl)cccc1NC(=O)c2oc(Br)cc2 | |
| 47d1b4f2867045abbcf9f0826874da5a [R]NC(=O)Cc1ccc(OCC)c(OCC)c1.[R]C(=O)N | |
| f52ff82a7a89aab385c2061baf899b90 [R]Cc1ccc(OCC)c(OCC)c1.[R]c2c(oc3ccccc23)C(=O)N | |
| c5cbdff73b3f20f45ecd43cea6127e89 [R]c1oc2ccccc2c1NC(=O)Cc3ccc(OCC)c(OCC)c3 | |
| 926a18ef866414ed99d058f0cbde6c5a [R]CC(=O)Nc1c(oc2ccccc12)C(=O)N.[R]OCC.[R]OCC | |
| c484d360090089d038f7b7f79e334a24 [R]c1cc(CC(=O)Nc2c(oc3ccccc23)C(=O)N)ccc1OCC | |
| be081c7aa49f7c26f9c02c86f2f99d04 [R]c1ccc(CC(=O)Nc2c(oc3ccccc23)C(=O)N)cc1OCC | |
| 3c4078ce6ede6d21b282d9be404cff4c [R]c1ccc(OCC)c(OCC)c1.[R]c2c(oc3ccccc23)C(=O)N | |
| ddb200a9a266daf4264a2199b10d42fc [R]Cc1ccc(OCC)c(OCC)c1.[R]C(=O)N | |
| 6abc7523ad8d8d0c9fe28b88781a53b5 [R]NC(=O)Cc1ccc(OCC)c(OCC)c1 | |
| 4511764461ceb95a49e83aa1670f7e0f [R]CC.[R]CC(=O)Nc1c(oc2ccccc12)C(=O)N.[R]OCC | |
| b30b1924158c95ae8179bec55fe72a73 [R]CC.[R]CC.[R]CC(=O)Nc1c(oc2ccccc12)C(=O)N | |
| e39ee03ebdf9f9915f92b55472f65f0a [R]CC.[R]CC.[R]C(=O)Nc1c(oc2ccccc12)C(=O)N | |
| 653648e84c9bd139617f58d590c829ee [R]CC.[R]CC.[R]c1c(oc2ccccc12)C(=O)N | |
| bcba2f1507d6ef5e44a926fb9fd9ea60 [R]CC.[R]C(=O)Nc1c(oc2ccccc12)C(=O)N | |
| 1722037da1efd6139f9d60d51ffbc1f6 [R]CC.[R]CC(=O)Nc1c(oc2ccccc12)C(=O)N | |
| ecd21fe637b612a0fcbe47c288229ef8 [R]CC(=O)Nc1c(oc2ccccc12)C(=O)N | |
| 3d24386fac032a7e481e5a26f3334d6a [R]CC.[R]OCC.[R]C(=O)Nc1c(oc2ccccc12)C(=O)N | |
| f2554a4684d873374f0cf3165c6f4190 [R]CC.[R]OCC.[R]c1c(oc2ccccc12)C(=O)N | |
| 2725d1cb9bfb9cb6a9876588de865bed [R]OCC.[R]C(=O)Nc1c(oc2ccccc12)C(=O)N | |
| c669bf7684ff5351bc263bde41eb8d26 [R]CC(=O)Nc1c(oc2ccccc12)C(=O)N.[R]OCC | |
| 1b9efbc665fee09813cafea5497a3776 [R]OCC.[R]OCC.[R]c1c(oc2ccccc12)C(=O)N | |
| c4a97fd592ffcaaff98961a158360e16 [R]OCC.[R]OCC.[R]C(=O)Nc1c(oc2ccccc12)C(=O)N | |
| 6dd8dd8ae8c725e76d99dd739cf4ba97 [R]c1c2C(=O)N(C)C(=O)N(C)c2c3cnc4ccccc4n13 | |
| 5525137226494742762d28ab017f52ee [R]Cc1ccccc1.[R]NC(=O)c2occc2.[R]C(=O)N | |
| abd0ef21f1502cde1b9475d50824081a [R]C(=O)Nc1sc(Cc2ccccc2)cc1C(=O)N | |
| 1b613539c18fade65a00476d2414d5eb [R]c1cc(Cc2ccccc2)sc1NC(=O)c3occc3 | |
| c2a920f3dee5146fa58d54499e87116d [R]c1occc1.[R]c2sc(Cc3ccccc3)cc2C(=O)N | |
| adec4ec515d21ed18e5e0f7408aa6675 [R]Cc1cc(C(=O)N)c(NC(=O)c2occc2)s1 | |
| 97f597d2cfdff4521b9f82ba8a720f61 [R]Cc1ccccc1.[R]NC(=O)c2occc2 | |
| 08cc6bc46ad7149877169183a5ae3093 [R]Cc1ccccc1.[R]c2occc2 | |
| 5cbbad836921e11908365fbfe4a263d2 [R]NC(=O)c1occc1.[R]c2ccccc2 | |
| 62022f10c3ed221686058bc72717a557 [R]Cc1ccccc1.[R]C(=O)N.[R]c2occc2 | |
| b564492a945fc495c5c6606b91d3c4b8 [R]C(=O)N.[R]c1occc1.[R]c2ccccc2 | |
| 12d87308685e6917802c7736bed446e1 [R]NC(=O)c1occc1.[R]C(=O)N.[R]c2ccccc2 | |
| f288d59990314dcbf9fd03e62d2799f9 [R]c1sc(Cc2ccccc2)cc1C(=O)N | |
| f7e08cb1703912fbea89f31d22b35519 [R]c1cc(C(=O)N)c(NC(=O)c2occc2)s1 | |
| 9f451a00815f6c8519245b8462fd15f0 [R]CSC1=Nc2[nH]ncc2C(=O)N1c3ccccc3 | |
| a3dec046b2bc9b2f60f8fe104000f1f1 [R]SCc1csc(C)n1.[R]c2ccccc2 | |
| 673ddb1b5e5924d37f83122d99d4ee10 [R]N1C(=Nc2[nH]ncc2C1=O)SCc3csc(C)n3 | |
| 177ec15504e4151dca9c74637e61038b [R]Cc1csc(C)n1.[R]c2ccccc2 | |
| 809c7de92ca8ba996dd2f0106938b79f [R]C1=Nc2[nH]ncc2C(=O)N1c3ccccc3 | |
| 5cde86cc4a2f39e9d840725a21384db2 [R]SC1=Nc2[nH]ncc2C(=O)N1c3ccccc3 | |
| 5d799ff2d6e1959f59215140fb8683b0 [R]C(=O)Nc1ccccc1N2CCOCC2 | |
| f012ff4eb3f3df27ceafaf5167f9a133 [R]c1ccccc1NC(=O)c2oc(Br)cc2 | |
| b8c1a7539465c1afaa0a7988065b15ba [R]c1oc(Br)cc1.[R]c2ccccc2N3CCOCC3 | |
| 5e164fb4601bbc59d4157fdff8ee2657 [R]NC(=O)c1oc(Br)cc1.[R]N2CCOCC2 | |
| b0716130ae0513ec6b6cc2e58996b470 [R]c1ccccc1N2CCOCC2 | |
| d5a8d93a39fb0eb8f82b4df18339ed6f [R]N1CCOCC1.[R]c2oc(Br)cc2 | |
| ed057bd5cf9c4ee5493db2b9b708f0b4 [R]NC(=O)Cc1cc(OC)c(OC)c(OC)c1.[R]C(=O)N | |
| d40017be5063e4de3f303650901dead1 [R]Cc1cc(OC)c(OC)c(OC)c1.[R]c2sccc2C(=O)N | |
| 3fe1f30fc7773d42ff66de65fb3d324a [R]c1ccsc1NC(=O)Cc2cc(OC)c(OC)c(OC)c2 | |
| 973a4fa1c787e66930b0ee0fa793efc6 [R]CC(=O)Nc1sccc1C(=O)N.[R]OC.[R]OC.[R]OC | |
| c8d00b6fd9fa52125461169720430890 [R]c1cc(OC)c(OC)c(OC)c1.[R]c2sccc2C(=O)N | |
| c630820e27e94bef311a9f62fabe2169 [R]Cc1cc(OC)c(OC)c(OC)c1.[R]C(=O)N | |
| 60b2d40f8751497ba5d2f8417841738a [R]Cc1cc(OC)c(OC)c(OC)c1 | |
| d222f4df33ec9f609311330ca04dd55d [R]C(=O)N.[R]c1cc(OC)c(OC)c(OC)c1 | |
| 816154b706310b4cc02165bda5b80086 [R]NC(=O)Cc1cc(OC)c(OC)c(OC)c1 | |
| 932c100791f22e0243672834390c98d8 [R]CC(=O)Nc1sccc1C(=O)N.[R]OC.[R]OC | |
| b540731ec9f2e8b4d40524a13789b897 [R]CC(=O)Nc1sccc1C(=O)N.[R]OC | |
| 73dd4f953cfb3981a86368f3d96b0795 [R]OC.[R]C(=O)Nc1sccc1C(=O)N | |
| 40c005ab577b87060fac5b729b64e217 [R]OC.[R]OC.[R]C(=O)Nc1sccc1C(=O)N | |
| 514524e0cebc285b554ded4ad81b760d [R]OC.[R]OC.[R]OC.[R]c1sccc1C(=O)N | |
| 5e01600e277117dbfcb0d6315f10a219 [R]OC.[R]OC.[R]OC.[R]C(=O)Nc1sccc1C(=O)N | |
| f606f5bdd28980d7675181c1c9164906 [R]c1ccc2nc(COC(=O)c3n[nH]c4ccccc34)[nH]c2c1.C[R][R]CC | |
| 6e2368f9c05edc9a744b3adafa3be9c4 [R]Cc1nc2ccc(cc2[nH]1)S(=O)(=O)N(CC)CC.[R]c3n[nH]c4ccccc34 | |
| 1be00707ad02187f835cde4ff502a668 [R]COC(=O)c1n[nH]c2ccccc12.[R]S(=O)(=O)N(CC)CC | |
| 6f0a67de32b75550c73567c41c6bbb23 [R]C(=O)OCc1nc2ccc(cc2[nH]1)S(=O)(=O)N(CC)CC | |
| e883360b113b85cb5647054e23a1e52c [R]CC.[R]c1ccc2nc(COC(=O)c3n[nH]c4ccccc34)[nH]c2c1 | |
| 6747f92232956ad2fe461a775b4fc2ca [R]c1ccc2nc(COC(=O)c3n[nH]c4ccccc34)[nH]c2c1 | |
| 1b4876f0591fb7eda76de20cf4f50eec [R]c1nc2ccc(cc2[nH]1)S(=O)(=O)N(CC)CC.[R]c3n[nH]c4ccccc34 | |
| f0c131878c56e49ec4510773d3032a13 [R]Cc1nc2ccc(cc2[nH]1)S(=O)(=O)N(CC)CC | |
| 0b7d0d4d051502db0bde38c84926e13d [R]OC(=O)c1n[nH]c2ccccc12.[R]S(=O)(=O)N(CC)CC | |
| d347f53b907d6cf19cb8971c2993d2ca O=C(COC(=O)c1n[nH]c2ccccc12)Nc3cc[R]([R]N4CCCC4)cc3 | |
| 37c2fc6633717bc12cec74558e447e74 [R]CC(=O)Nc1ccc(cc1)S(=O)(=O)N2CCCC2.[R]c3n[nH]c4ccccc34 | |
| 4aa78f272074bafbdf112aa83e83dfdc [R]COC(=O)c1n[nH]c2ccccc12.[R]c3ccc(cc3)S(=O)(=O)N4CCCC4 | |
| 211a361440eaca0157411e2e38e9426e [R]S(=O)(=O)c1ccc(NC(=O)COC(=O)c2n[nH]c3ccccc23)cc1 | |
| 211e2ebb40da88d5f4c4168d22287714 [R]C(=O)OCC(=O)Nc1ccc(cc1)S(=O)(=O)N2CCCC2 | |
| aae2328092dded52d46304700e5e0c09 [R]NC(=O)COC(=O)c1n[nH]c2ccccc12.[R]S(=O)(=O)N3CCCC3 | |
| 92e524a49df5729b634e9aa1d3ee652e [R]C(=O)Nc1ccc(cc1)S(=O)(=O)N2CCCC2.[R]c3n[nH]c4ccccc34 | |
| bb86c5000ce56fa174bf742efb73573c [R]c1ccc(cc1)S(=O)(=O)N2CCCC2.[R]c3n[nH]c4ccccc34 | |
| 1fadfd988d7ede855fb7a1aad4c70863 [R]OC(=O)c1n[nH]c2ccccc12.[R]c3ccc(cc3)S(=O)(=O)N4CCCC4 | |
| ebf7a808f5451b493f0b895a3256fc28 [R]c1ccc(NC(=O)COC(=O)c2n[nH]c3ccccc23)cc1 | |
| a7ab92e1c9912d0907717af315ab897d [R]NC(=O)COC(=O)c1n[nH]c2ccccc12.[R]N3CCCC3 | |
| 1287bb8f7948b4802f462aa87973ca60 [R]COC(=O)c1n[nH]c2ccccc12.[R]N3CCCC3 | |
| 18ca93677fa304b2020cce5a1fac2fbb [R]CC(=O)Nc1ccc(cc1)S(=O)(=O)N2CCCC2 | |
| 97b993193d4ecfdfa50b4138314adb32 [R]COC(=O)c1n[nH]c2ccccc12.[R]S(=O)(=O)N3CCCC3 | |
| 8f4a36fece7ff23d258bb7faf344b317 [R]OC(=O)c1n[nH]c2ccccc12.[R]S(=O)(=O)N3CCCC3 | |
| 47e1ef6371d1d49e6cefab78d9bb3f21 NC(=O)c1ccsc1NC(=O)c2cc[R]([R]N3CCCCC3)cc2 | |
| 0e6409500ea6d0fe659ed7c9a16e59f9 [R]NC(=O)c1ccc(cc1)S(=O)(=O)N2CCCCC2.[R]C(=O)N | |
| 9c97628a8dbf37cec2f387d39bed99a6 [R]c1ccc(cc1)S(=O)(=O)N2CCCCC2.[R]c3sccc3C(=O)N | |
| f058848a3ff47160f714277457e5fd27 [R]c1ccsc1NC(=O)c2ccc(cc2)S(=O)(=O)N3CCCCC3 | |
| 4adf462aad691cab806b4ddc8d9a6e35 [R]S(=O)(=O)c1ccc(cc1)C(=O)Nc2sccc2C(=O)N | |
| edb68a48c2775d99159d276eba32757f [R]C(=O)Nc1sccc1C(=O)N.[R]S(=O)(=O)N2CCCCC2 | |
| 24578fa439aa37b95a9076901431ec2f [R]c1ccc(cc1)C(=O)Nc2sccc2C(=O)N | |
| 749aaaec664c74104a64c0193312d136 [R]N1CCCCC1.[R]C(=O)Nc2sccc2C(=O)N | |
| 53c20e85b6493e6bbcf0ca3e294bfdc4 [R]N1CCCCC1.[R]c2sccc2C(=O)N | |
| b9159027b9704eab08a0348f88e807a6 [R]C(=O)N.[R]c1ccc(cc1)S(=O)(=O)N2CCCCC2 | |
| eaf0808b68839b1ff050ed99b105d44a [R]c1ccc(cc1)S(=O)(=O)N2CCCCC2 | |
| 31d023d483e816fa29ec7cede74a4707 [R]NC(=O)c1ccc(cc1)S(=O)(=O)N2CCCCC2 | |
| 402513aae80e67749bd76c9412133b3a [R]c1sccc1C(=O)N.[R]S(=O)(=O)N2CCCCC2 | |
| 9409b5971383ac876b653c3da553d570 [R]NC(=O)CSC1=Nc2ccccc2C(=O)N1CCCO.[R]C(=O)N | |
| de1f3a71c89ed51f9b93f422fd71f3e7 [R]CCCO.[R]SCC(=O)Nc1sccc1C(=O)N | |
| eb12228da8bddecb394fa3cb6fb72d68 [R]N1C(=Nc2ccccc2C1=O)SCC(=O)Nc3sccc3C(=O)N | |
| ad47483aa34623b6168b28eea2ec444b [R]CSC1=Nc2ccccc2C(=O)N1CCCO.[R]c3sccc3C(=O)N | |
| 685db0c50d47295021203e208c8d2543 [R]c1ccsc1NC(=O)CSC2=Nc3ccccc3C(=O)N2CCCO | |
| 510154ba2fb13119f02c3653c02f6034 [R]C1=Nc2ccccc2C(=O)N1CCCO.[R]c3sccc3C(=O)N | |
| 3bdbe20ac94187afc558058845c11d00 [R]SC1=Nc2ccccc2C(=O)N1CCCO.[R]c3sccc3C(=O)N | |
| aef6602b84152742a2f2d4cebf4ddf6d [R]CCCO.[R]CC(=O)Nc1sccc1C(=O)N | |
| 6088d6483e0a933a6dcf9b5b088ae92e [R]C(=O)N.[R]C1=Nc2ccccc2C(=O)N1CCCO | |
| bfa59561f00a6e2507ad4534ca4e950f [R]CSC1=Nc2ccccc2C(=O)N1CCCO.[R]C(=O)N | |
| 49d38401ec140ce2438b2a09121abf5d [R]CSC1=Nc2ccccc2C(=O)N1CCCO | |
| 09747049e11aa7f8cfed3394fc52c24e [R]SC1=Nc2ccccc2C(=O)N1CCCO | |
| 5433a46fe338c532c200bea5a5e6f407 [R]SC1=Nc2ccccc2C(=O)N1CCCO.[R]C(=O)N | |
| de86e30032cae7cf41a47e8337834187 [R]NC(=O)CSC1=Nc2ccccc2C(=O)N1CCCO | |
| d674681987ea5fe9ba2c3cb7ce96c855 [R]CC=C.[R]SCC(=O)Nc1sccc1C(=O)N | |
| 0876ecf5f54c69d4d191f90e28fd87fc [R]NC(=O)CSC1=Nc2sc(C)c(C)c2C(=O)N1CC=C.[R]C(=O)N | |
| f5f20f0dc499782e5e4fca200e47cfbc [R]CSC1=Nc2sc(C)c(C)c2C(=O)N1CC=C.[R]c3sccc3C(=O)N | |
| 69d21fcba06da63956fa968cbab1db99 [R]c1ccsc1NC(=O)CSC2=Nc3sc(C)c(C)c3C(=O)N2CC=C | |
| e041e2f1428a93d6a70b187434e414b9 [R]C1=Nc2sc(C)c(C)c2C(=O)N1CC=C.[R]c3sccc3C(=O)N | |
| 0e9671988b1b3f51c8c8bd27fc6af99a [R]SC1=Nc2sc(C)c(C)c2C(=O)N1CC=C.[R]c3sccc3C(=O)N | |
| 2e7894dc171f97fd06ba80b5121434a7 [R]N1C(=Nc2sc(C)c(C)c2C1=O)SCC(=O)Nc3sccc3C(=O)N | |
| 0eec0812a6962840801840ca00defe06 [R]C(=O)N.[R]C1=Nc2sc(C)c(C)c2C(=O)N1CC=C | |
| a8666cc7e7734e557fabfb34bc020527 [R]CSC1=Nc2sc(C)c(C)c2C(=O)N1CC=C.[R]C(=O)N | |
| 3db3040a159edf77f32a61f6ed6f14df [R]CSC1=Nc2sc(C)c(C)c2C(=O)N1CC=C | |
| 0145f4911c92e87ce5dd4a30b4f7f72c [R]SC1=Nc2sc(C)c(C)c2C(=O)N1CC=C | |
| b1726885c51f57408935307cb8cb44b6 [R]SC1=Nc2sc(C)c(C)c2C(=O)N1CC=C.[R]C(=O)N | |
| c855bb826d204847c752884745d26dcf [R]NC(=O)CSC1=Nc2sc(C)c(C)c2C(=O)N1CC=C | |
| 1cb9569d089b36fda12f3b2d736aecbb [R]CC1CCC(CC1)C(=O)NCCOC | |
| d6dc59b49c9d992c5d9669f9e8e095a4 [R]CCOC.[R]C1CCC(CN2C(=S)Nc3ccccc3C2=O)CC1 | |
| f9aa6211f9b4ab9a3f77b986c5f74722 [R]CN1C(=S)Nc2ccccc2C1=O.[R]C(=O)NCCOC | |
| 742a8c83751f429a7d747133dbca3862 [R]OC.[R]C1CCC(CN2C(=S)Nc3ccccc3C2=O)CC1 | |
| b4c89580692819e2aaa65ed2979c8c35 [R]C1CCC(CN2C(=S)Nc3ccccc3C2=O)CC1 | |
| 4619ae74f7b759b749fb44dd02c70af3 [R]NC(=O)C1CCC(CN2C(=S)Nc3ccccc3C2=O)CC1 | |
| 4de0018e9b8324bfafb9d9c144187c1a [R]CCOC.[R]CN1C(=S)Nc2ccccc2C1=O | |
| a67c5c45f09f985f5555f60457aadd85 [R]CCOC.[R]N1C(=S)Nc2ccccc2C1=O | |
| 3d41a061f2f6448017cc067317d10e63 [R]OC.[R]N1C(=S)Nc2ccccc2C1=O | |
| 359ed4c0f6260ea2b3f74f7cb3cfaa1d [R]CN1C(=S)Nc2ccccc2C1=O.[R]OC | |
| 0fe2e955e1c2c4d8d5f507a501fc0159 [R]N1C(=S)Nc2ccccc2C1=O.[R]C(=O)NCCOC | |
| 5968b0c41227322ae81a3648f13b5760 [R]C1=NOC(C1)C(=O)Nc2cnn(CCC)c2 | |
| 29c3e4be5c3f0843ed90cec5cda75b4e [R]C(=O)Nc1cnn(CCC)c1.[R]c2cccc(Br)c2 | |
| e21e98d81c88300b5bddaf11b1fa67e9 [R]C1CC(=NO1)c2cccc(Br)c2.[R]c3cnn(CCC)c3 | |
| f93ed475b6e90f7f66e947f10a3b65dc [R]CCC.[R]NC(=O)C1CC(=NO1)c2cccc(Br)c2 | |
| 9e87f2994d7d0441622eadcae32d21f0 [R]n1cc(NC(=O)C2CC(=NO2)c3cccc(Br)c3)cn1 | |
| c9a2693c7aaee66e80b271e801796def [R]c1cccc(Br)c1.[R]c2cnn(CCC)c2 | |
| f6cff4405f3c52454579368239383ea2 [R]CCC.[R]C1CC(=NO1)c2cccc(Br)c2 | |
| 9c8a0d93d8b4ebda67f98311eeb73c21 [R]C1CC(=NO1)c2cccc(Br)c2 | |
| 0050e49484a41d567ab4771486edca3b [R]NC(=O)C1CC(=NO1)c2cccc(Br)c2 | |
| 818442322b22bc8b64d685bc6a540ef1 [R]NC(=O)c1cccs1.[R]C(=O)N | |
| 73fc69a0eb6e5c111e6b1fd4ec0aab81 [R]C(=O)Nc1sccc1C(=O)N | |
| 8aa5c5326a644e2127ea68d2e1c5b2de [R]c1cccs1.[R]c2sccc2C(=O)N | |
| c62a239754f29bb6d43f052325c19f59 [R]c1ccsc1NC(=O)c2cccs2 | |
| 2d9d7a00d3ea96d369b3104a465a054a [R]CCCCCC(=O)Nc1ccc(C)cc1 | |
| f202eed7a35efa6df47e488dfb28905a [R]CCCCCC1NC(=O)NC1C.[R]c2ccc(C)cc2 | |
| e2d7f525f426298f7e9de9e7f6bc7710 [R]C1NC(=O)NC1C.[R]C(=O)Nc2ccc(C)cc2 | |
| d1c00dd9b6dce99667be549f141c5bc0 [R]NC(=O)CCCCCC1NC(=O)NC1C | |
| b18057b3cea9b76fb3c6f639da427b0d [R]C1NC(=O)NC1C.[R]c2ccc(C)cc2 | |
| 8b2f18879f679d3743824ece90a2d174 [R]CCCCCC1NC(=O)NC1C | |
| 1c2c48a7e90ab7cfa055739beb02f526 [R]CCCCCC(=O)NCCc1ccccc1 | |
| 268704d0439ae9b3b06be7d7922d8bd0 [R]CCCCCC1NC(=O)NC1C.[R]CCc2ccccc2 | |
| 2c76a172260d87b9c472b0fedcc867c2 [R]C1NC(=O)NC1C.[R]C(=O)NCCc2ccccc2 | |
| 5bd9b1bd8a4a3be94042aeb69371bc93 [R]CCNC(=O)CCCCCC1NC(=O)NC1C | |
| 718307a75a311d122049772e0a9761f4 [R]CCc1ccccc1.[R]C2NC(=O)NC2C | |
| 741ae71be965c22205c8ea67d103505d [R]C1NC(=O)NC1C.[R]c2ccccc2 | |
| 6d45469b4669e11d960115ca6e61382b [R]CCCCCC1NC(=O)NC1C.[R]c2ccccc2 | |
| c03879b70eefee57f4d717fff828497f [R]C1=NOC(C1)C(=O)Nc2ccc(cc2)C(=O)C | |
| b73ba3e6ee37d3b8b313a9b1f427cd9c [R]C(=O)Nc1ccc(cc1)C(=O)C.[R]c2ccc(F)cc2 | |
| 1dc6e7a9148b03c5c6b8ef5d15cedf62 [R]C1CC(=NO1)c2ccc(F)cc2.[R]c3ccc(cc3)C(=O)C | |
| f582c37f0e9ca3752d4a616aa7bdc300 [R]c1ccc(NC(=O)C2CC(=NO2)c3ccc(F)cc3)cc1 | |
| e04ab9b214f81ffa4c2c7b036f205c22 [R]NC(=O)C1CC(=NO1)c2ccc(F)cc2.[R]C(=O)C | |
| abd43aea30562dcda1f6bff76e072f4d [R]c1ccc(F)cc1.[R]c2ccc(cc2)C(=O)C | |
| 605d52b7002788f97a794fd890ba60e0 [R]C1CC(=NO1)c2ccc(F)cc2.[R]C(=O)C | |
| aa205a7c420e4fbf10c2a7783977f50f [R]NC(=O)C1CC(=NO1)c2ccc(F)cc2 | |
| 7f982ad6a43fe314997cfcb9a2e77448 [R]\C(=C(/C)\NCc1cc(OC)c(OC)c(OC)c1)\C#N | |
| 53a4bf5d568a97d038a4caf7c4f35224 [R]CN\C(=C(/C#N)\C(=O)N)\C.[R]OC.[R]OC.[R]OC | |
| cd45c53f8ca1ec2036411be1e00f393c [R]NCc1cc(OC)c(OC)c(OC)c1.NC(=O)[R][R]#N | |
| 6b6541dd3881327f7d42052372238cec [R]NCc1cc(OC)c(OC)c(OC)c1.[R]C#N | |
| 9f526c3cb33d1715c4ff001ee0474e04 [R]Cc1cc(OC)c(OC)c(OC)c1.[R]C#N | |
| c76a823c591b9b51389cede68b3da393 [R]c1cc(OC)c(OC)c(OC)c1 | |
| f3dee2a1dd49f282cb85eafc99855b6b [R]C#N.[R]c1cc(OC)c(OC)c(OC)c1 | |
| ddde94b9980215ea190e9958a8f02097 [R]NCc1cc(OC)c(OC)c(OC)c1 | |
| 72969129b8165abaf5b97e037e0b0cb1 [R]c1cc(OC)c(OC)c(OC)c1.NC(=O)[R][R]#N | |
| 0f36f83113bbfe9ab73c65acb1cc2534 [R]Cc1cc(OC)c(OC)c(OC)c1.NC(=O)[R][R]#N | |
| 7e5d4dae1ce12cb2345c70dbadbd6a19 [R]NCc1cc(OC)c(OC)c(OC)c1.[R]C(=O)N | |
| 012b45bdc5bc3bb311bb65ece7edeee7 [R]CN\C(=C(/C#N)\C(=O)N)\C.CO[R]=[R]OC | |
| 533e8fe4a37cf051e79cc3c3edcc310b [R]CN\C(=C(/C#N)\C(=O)N)\C.[R]OC | |
| 6ecd6e048c83580e0f6736ffb4159895 [R]N\C(=C(/C#N)\C(=O)N)\C.CO[R]=[R]OC | |
| 0d367ae1ea9eaeeac4d5874dd5f7e532 [R]\C(=C(/C#N)\C(=O)N)\C.CO[R]=[R]OC | |
| 08d3dab5ebe1b743f07c3a08568ee5f3 [R]CN\C(=C(/C#N)\C(=O)N)\C.CO[R][R]OC | |
| e8135ba00e7da16f78347f1f5fa50ffd [R]N\C(=C(/C#N)\C(=O)N)\C.CO[R][R]OC | |
| 51e77046fc7b8436599bb1dbb3c6562e [R]\C(=C(/C#N)\C(=O)N)\C.CO[R][R]OC | |
| cc859111a12851fd4b9cd4950becda7c [R]CN\C(=C(/C#N)\C(=O)N)\C.[R]OC.[R]OC | |
| f26d539bb1a96bc97983d8b9461a9efc [R]N\C(=C(/C#N)\C(=O)N)\C.[R]OC.[R]OC | |
| 0baecca109e6ac9a1e0faba9f61b150c [R]OC.[R]OC.[R]\C(=C(/C#N)\C(=O)N)\C | |
| 4defb6f3e182e7508557e2169c6c78c5 [R]\C(=C(/C#N)\C(=O)N)\C.CO[R][R](=[R]OC)OC | |
| 142edf5ff0045ba5144b1b0ed45d709b [R]N\C(=C(/C#N)\C(=O)N)\C.CO[R][R](=[R]OC)OC | |
| 3870725ded662e004600d02920ce4e6c [R]C(=O)Nc1ccccc1C(=O)OC.[R]c2cnn(CC)c2C | |
| 9c44e5a9fdb3b02a9a7ae4451bf95d7f [R]C1CC(=NO1)c2cnn(CC)c2C.[R]c3ccccc3C(=O)OC | |
| e39eb92f1fb05397f8475b398b93803e [R]c1ccccc1NC(=O)C2CC(=NO2)c3cnn(CC)c3C | |
| 6c5b06fbb25869fa142aa56c567a9d05 [R]CC.[R]C1=NOC(C1)C(=O)Nc2ccccc2C(=O)OC | |
| 7ddf7b50cc0652280c7a972035a297bf [R]NC(=O)C1CC(=NO1)c2cnn(CC)c2C.[R]C(=O)OC | |
| 3184d661bb943702c842207fa74a12a2 [R]c1ccccc1C(=O)OC.[R]c2cnn(CC)c2C | |
| 33658707010924498d42bacfec0bcda3 [R]CC.[R]C(=O)Nc1ccccc1C(=O)OC | |
| 4521d4223331d0e3b3e88d44f17ab571 [R]C1CC(=NO1)c2cnn(CC)c2C.[R]C(=O)OC | |
| 6b89ae13deed813d1967aea061d41136 [R]NC(=O)C1CC(=NO1)c2cnn(CC)c2C | |
| 004d5b56f14cb20799a01662e27ee3e4 [R]C1=NOC(C1)C(=O)Nc2ccccc2C(=O)OC | |
| 22fa2b476dac74ab601ae61e6314f8a0 [R]Cc1ccc(cc1)C(=O)N2CCN(CC2)c3ccccc3 | |
| af2216d0c59c0559f0fae28bcdad09d2 [R]C(=O)c1ccc(CN2C(=O)Nc3ccccc3C2=O)cc1.[R]c4ccccc4 | |
| 742bfbfe86f544e39dfb0facf1e03c79 [R]N1CCN(CC1)C(=O)c2ccc(CN3C(=O)Nc4ccccc4C3=O)cc2 | |
| 3ac4ac0967831a690053d1b8a96e9159 [R]CN1C(=O)Nc2ccccc2C1=O.[R]C(=O)N3CCN(CC3)c4ccccc4 | |
| 71cf0432ac79d594a5820c07d4c889f9 [R]c1ccccc1.[R]c2ccc(CN3C(=O)Nc4ccccc4C3=O)cc2 | |
| 752318a18c39ef7ee2b11bc50efeff12 [R]CN1C(=O)Nc2ccccc2C1=O.[R]N3CCN(CC3)c4ccccc4 | |
| 100a8ebac62c3c59f7e2161df12265f6 [R]N1CCN(CC1)c2ccccc2.[R]N3C(=O)Nc4ccccc4C3=O | |
| b3b2ceffecaee5413c169f403c181934 [R]C(=O)c1ccc(CN2C(=O)Nc3ccccc3C2=O)cc1 | |
| 041860a24a7990aa70541c1047b8647a [R]N1C(=O)Nc2ccccc2C1=O.[R]C(=O)N3CCN(CC3)c4ccccc4 | |
| 007dd873c3ce282372f4b1dad8be1521 [R]C(=O)Nc1cc(OC)c(OC)c(OC)c1.[R]c2cccc(OC)c2OC | |
| 4a630ad7f1743afede814d7b19904ac2 [R]C1CC(=NO1)c2cccc(OC)c2OC.[R]c3cc(OC)c(OC)c(OC)c3 | |
| 8d66343ea324e284927131d516ba6d15 [R]OC.[R]OC.[R]C1=NOC(C1)C(=O)Nc2cc(OC)c(OC)c(OC)c2 | |
| d46de2f3ef36bad23f9ec61efa77bc22 [R]NC(=O)C1CC(=NO1)c2cccc(OC)c2OC.[R]OC.[R]OC.[R]OC | |
| 186d62ec2e1cb58439bb713d1eacbbd4 [R]c1cc(OC)c(OC)c(OC)c1.[R]c2cccc(OC)c2OC | |
| 577bc12e50a60afcdfcc9940e5cddc78 [R]OC.[R]OC.[R]C(=O)Nc1cc(OC)c(OC)c(OC)c1 | |
| 6311f51a0b08df6893c9b66a602d6d03 [R]OC.[R]C1=NOC(C1)C(=O)Nc2cc(OC)c(OC)c(OC)c2 | |
| cbfccf26bcfa01a7bbf50fc413b3b3c2 [R]C1=NOC(C1)C(=O)Nc2cc(OC)c(OC)c(OC)c2 | |
| afef47e2838c255fb528f8224c8e4277 [R]OC.[R]OC.[R]OC.[R]C1CC(=NO1)c2cccc(OC)c2OC | |
| 3ff400286acf5675d91f73fb2ba39c6b [R]OC.[R]OC.[R]C1CC(=NO1)c2cccc(OC)c2OC | |
| 0a0cf87080aa0d5b31c468dff775c8da [R]NC(=O)C1CC(=NO1)c2cccc(OC)c2OC.[R]OC.[R]OC | |
| c73db2e39376e52e5e82fc233fb44160 [R]NC(=O)C1CC(=NO1)c2cccc(OC)c2OC.[R]OC | |
| c85923693f831889914046e3151dda6b [R]NC(=O)C1CC(=NO1)c2cccc(OC)c2OC | |
| 31de523fe7b6880da688c51ede69a632 [R]C(=O)Nc1ccccc1C(=O)OC.[R]c2cn(CC)nc2C | |
| 9aa43d8d1f22dddefe9d800daa4a9af8 [R]C1CC(=NO1)c2cn(CC)nc2C.[R]c3ccccc3C(=O)OC | |
| f4d6889c42f0c843e36db976b4e32227 [R]c1ccccc1NC(=O)C2CC(=NO2)c3cn(CC)nc3C | |
| 09a7cff3bf370e22d09674acadc27d5f [R]NC(=O)C1CC(=NO1)c2cn(CC)nc2C.[R]C(=O)OC | |
| d92a2001247749c8385e6396e0a4608e [R]c1ccccc1C(=O)OC.[R]c2cn(CC)nc2C | |
| a4f79afe2284b54d3ed2fb7f8de1ec5e [R]C1CC(=NO1)c2cn(CC)nc2C.[R]C(=O)OC | |
| 5b7464d89b1b13adb85641fd3b688b52 [R]NC(=O)C1CC(=NO1)c2cn(CC)nc2C | |
| 363967b01fd94ffd925e42e9ebfdec2b [R]C(=O)Nc1ccc(cc1)C(=O)C.[R]c2cccc(OC)c2 | |
| 57ef527e708018b3e5c325756be1b859 [R]C1CC(=NO1)c2cccc(OC)c2.[R]c3ccc(cc3)C(=O)C | |
| 3604b8a6ca32c137093c3552bc5a1024 [R]c1ccc(NC(=O)C2CC(=NO2)c3cccc(OC)c3)cc1 | |
| b530cac9e047c57960874be252be297b [R]OC.[R]C1=NOC(C1)C(=O)Nc2ccc(cc2)C(=O)C | |
| 0fdb6ae9325bfa4d65ac11421904cdbb [R]NC(=O)C1CC(=NO1)c2cccc(OC)c2.[R]C(=O)C | |
| 53ad373e385df90d4a47d69bf5ab5c84 [R]c1ccc(cc1)C(=O)C.[R]c2cccc(OC)c2 | |
| f1191cdcd3248a83f8c871f61d2fced8 [R]OC.[R]C(=O)Nc1ccc(cc1)C(=O)C | |
| a833ec89d3c027d1e6883368405fd1f8 [R]C1CC(=NO1)c2cccc(OC)c2.[R]C(=O)C | |
| bf9725730d023a9029f32476b227109a [R]C1CC(=NO1)c2cccc(OC)c2 | |
| a4e4d90e2237e60c5e2391de8771b8e4 [R]NC(=O)C1CC(=NO1)c2cccc(OC)c2 | |
| cc433f065f55ba69e56eda367e5dfe84 [R]Cc1cn2ccccc2n1.[R]c3cc(OC)c(OC)c(OC)c3 | |
| 561b9a5df8be79864de5faeec6f8fc8f [R]CNC(=O)c1cc(OC)c(OC)c(OC)c1 | |
| 73f5e13bf68659bd4406a85de4eae877 [R]OC.[R]OC.[R]OC.[R]C(=O)NCc1cn2ccccc2n1 | |
| bda017ec93e7c9556d38433c94b9ea09 [R]c1cc(OC)c(OC)c(OC)c1.[R]c2cn3ccccc3n2 | |
| 201b7959d808bd02e8d44b0f7154e568 [R]OC.[R]OC.[R]C(=O)NCc1cn2ccccc2n1 | |
| 2e378386be9cd6dd9d2d78be4f017e88 [R]OC.[R]C(=O)NCc1cn2ccccc2n1 | |
| e260b517fedb06e0547b072244694196 [R]C(=O)NCc1cn2ccccc2n1 | |
| 74cda18ffa0d3b3911a2a6774d6f34a1 [R]Cc1cn2ccccc2n1.[R]OC.[R]OC | |
| 7c328f8502b41033b4e467e9ce0d98a7 [R]OC.[R]OC.[R]c1cn2ccccc2n1 | |
| 25c0bf1c0d1f56fbc934e69c60503875 [R]OC.[R]OC.[R]OC.[R]c1cn2ccccc2n1 | |
| a611fe87d7cfd51a15da65f7433f5259 [R]Cc1cn2ccccc2n1.[R]OC.[R]OC.[R]OC | |
| 2ec607314f69a496665fe5b8192daba2 [R]NC(=O)c1cc(OC)c(OC)c(OC)c1 | |
| 429658b4dd4933e6cffa3f6ce437478c [R]C(=O)Nc1ccc(OC)c(OC)c1.[R]c2cccc(OC)c2 | |
| 622056e4232e18d064d1e3b56bdfc5bd [R]C1CC(=NO1)c2cccc(OC)c2.[R]c3ccc(OC)c(OC)c3 | |
| 672e332a130f27c8bbdd41dd5de176b5 [R]OC.[R]C1=NOC(C1)C(=O)Nc2ccc(OC)c(OC)c2 | |
| b69b6116a1d08822cac53c14dbb76331 [R]NC(=O)C1CC(=NO1)c2cccc(OC)c2.[R]OC.[R]OC | |
| 22bec7dd4abb97be9785e3ba45c2dacb [R]c1cccc(OC)c1.[R]c2ccc(OC)c(OC)c2 | |
| 85a1d63837783f03254d41f7c6b82a05 [R]OC.[R]C(=O)Nc1ccc(OC)c(OC)c1 | |
| 86832d8f333d09334fb96ab5ba5c9cf0 [R]OC.[R]OC.[R]C1CC(=NO1)c2cccc(OC)c2 | |
| 3e87e10517de967a54dff344df271e16 [R]OC.[R]C1CC(=NO1)c2cccc(OC)c2 | |
| fbbe88226a9d47bc464c58ae6cbc7df5 [R]C1=NOC(C1)C(=O)Nc2ccc(OC)c(OC)c2 | |
| 538085ffcfc59d92cf23c2075a19f0bb [R]NC(=O)C1CC(=NO1)c2cccc(OC)c2.[R]OC | |
| 957f5e0bc75e8ea251ca193e4f8e4faf [R]C(=O)Nc1ccccc1C(=O)OC.[R]c2ccc(F)cc2 | |
| d65ca6745007b2d94d701d0f8752a639 [R]C1CC(=NO1)c2ccc(F)cc2.[R]c3ccccc3C(=O)OC | |
| c861a3a0b5e6510edb21465393a75d86 [R]c1ccccc1NC(=O)C2CC(=NO2)c3ccc(F)cc3 | |
| 101f8b204bb40dc4b226756399f2e961 [R]NC(=O)C1CC(=NO1)c2ccc(F)cc2.[R]C(=O)OC | |
| 31d97d94d1d090715db8394a82b30d34 [R]C(=O)Nc1ccccc1C(=O)OC | |
| dc742b64ff87100f0e7c996cc4e0eb4c [R]c1ccc(F)cc1.[R]c2ccccc2C(=O)OC | |
| c5b1797345f9d08efb357f569eecf2bf [R]C1CC(=NO1)c2ccc(F)cc2.[R]C(=O)OC | |
| c571bc164230bf12d923545a1a7508a6 [R]C(=O)Nc1cc(OC)c(OC)c(OC)c1.[R]c2cccc(OC)c2 | |
| 1d4ac5b6330c45d3615cdfc2bc7af0b4 [R]C1CC(=NO1)c2cccc(OC)c2.[R]c3cc(OC)c(OC)c(OC)c3 | |
| 0d599cf4a73f109970061d68a4d9be15 [R]NC(=O)C1CC(=NO1)c2cccc(OC)c2.[R]OC.[R]OC.[R]OC | |
| 227dd16c3c10f418ae34f2e011eaec3a [R]c1cccc(OC)c1.[R]c2cc(OC)c(OC)c(OC)c2 | |
| 7d51d8292814ebe3fda87bcc24a55166 [R]OC.[R]C(=O)Nc1cc(OC)c(OC)c(OC)c1 | |
| f3643781f3ceffdd1b0ed777ed663a36 [R]OC.[R]OC.[R]OC.[R]C1CC(=NO1)c2cccc(OC)c2 | |
| 40025d98004f0739f5c2012c024cb27e [R]C1=NOC(C1)C(=O)Nc2ccc(cc2)C#N | |
| 3bdeacae1f7176b37f3d861733e03490 [R]C(=O)Nc1ccc(cc1)C#N.[R]c2ccc(F)cc2 | |
| 23ccdba6582361c09d24b86500a5890a [R]C1CC(=NO1)c2ccc(F)cc2.[R]c3ccc(cc3)C#N | |
| 5f9426da999c413a0d923df5590390a9 [R]NC(=O)C1CC(=NO1)c2ccc(F)cc2.[R]C#N | |
| e83c76c9cc11a0036c67218055615880 [R]c1ccc(F)cc1.[R]c2ccc(cc2)C#N | |
| 738c3c6b5cd353e9725696a8bed55059 [R]C#N.[R]C1CC(=NO1)c2ccc(F)cc2 | |
| 5f9ef1c568c527d4afcaf223bb21c97f [R]C1CC(=NO1)c2ccc(F)cc2 | |
| 17cd02eb4a46586ac6534c803810e1a8 [R]SCC(=O)Nc1cc(C)[nH]n1.[R]c2ccc(CC)cc2 | |
| 3e81dc876f263b104dcd3bad9280048c [R]CSC1=Nc2[nH]ncc2C(=O)N1c3ccc(CC)cc3.[R]c4cc(C)[nH]n4 | |
| 6902b9bdc67b13edbaf911fa7bdda80d [R]NC(=O)CSC1=Nc2[nH]ncc2C(=O)N1c3ccc(CC)cc3 | |
| 7deeaa7fda2aaeb43d847b9932711ece [R]CC.[R]N1C(=Nc2[nH]ncc2C1=O)SCC(=O)Nc3cc(C)[nH]n3 | |
| fd9f800980adfc1235fce707a40b080f [R]C1=Nc2[nH]ncc2C(=O)N1c3ccc(CC)cc3.[R]c4cc(C)[nH]n4 | |
| fe63150ef281b1e4b2ef4ae48ed9c31e [R]SC1=Nc2[nH]ncc2C(=O)N1c3ccc(CC)cc3.[R]c4cc(C)[nH]n4 | |
| 4cfc601d38de087206b1ad833f5db008 [R]CC(=O)Nc1cc(C)[nH]n1.[R]c2ccc(CC)cc2 | |
| 7a5f804d933dbc4d0497128ac96edb1a [R]C(=O)Nc1cc(C)[nH]n1.[R]c2ccc(CC)cc2 | |
| 51048a4dbe70c4ced0409a3e19051733 [R]C1=Nc2[nH]ncc2C(=O)N1c3ccc(CC)cc3 | |
| 2634e2e5619d979072278f1f938afbd8 [R]CSC1=Nc2[nH]ncc2C(=O)N1c3ccc(CC)cc3 | |
| 97cb1413961056958d37eee41538781e [R]SC1=Nc2[nH]ncc2C(=O)N1c3ccc(CC)cc3 | |
| 909db7f1d9775888e64a42910c5fef03 [R]N1C(=Nc2[nH]ncc2C1=O)SCC(=O)Nc3cc(C)[nH]n3 | |
| 80da4309452ec0e4671ba8a9016cefa0 [R]NC(=O)c1occc1.[R]C(=O)N | |
| 04c5f91a3e254f5f3f358a43cc43719b [R]C(=O)Nc1c(oc2ccccc12)C(=O)N | |
| 738317f8eb66638640c203ce09e3b7bd [R]c1occc1.[R]c2c(oc3ccccc23)C(=O)N | |
| 3b4746f2cdf2d7bf9f8f3ff98d0b62b4 [R]c1oc2ccccc2c1NC(=O)c3occc3 | |
| 69f9cdfa7b1b73c8f34681f779d73a10 [R]c1c(oc2ccccc12)C(=O)N | |
| 99858e94a6329fda3f16b7c0ddf216a5 [R]CC1CCC(CC1)C(=O)N2CCN(CC2)c3ccccc3 | |
| facef9e9cd374eac0036a699d038c91b [R]C(=O)C1CCC(CN2C(=O)Nc3ccccc3C2=O)CC1.[R]c4ccccc4 | |
| c0f5e2ba4b2413595cd18c27f7f97423 [R]N1CCN(CC1)C(=O)C2CCC(CN3C(=O)Nc4ccccc4C3=O)CC2 | |
| afec3db085c422968906aaef6100bdc2 [R]C1CCC(CN2C(=O)Nc3ccccc3C2=O)CC1.[R]c4ccccc4 | |
| 3347678df1f43126d1f580ccef63417d [R]C(=O)C1CCC(CN2C(=O)Nc3ccccc3C2=O)CC1 | |
| 4319c30fe787c931b85a3781556263ab [R]Cc1ccc(cc1)C(=O)NCCCOC | |
| b6566da3a738cd251fd8c16d8617acbd [R]CCCOC.[R]c1ccc(CN2C(=O)Nc3ccccc3C2=O)cc1 | |
| 6e9d5e9764622d15c82263116272bb26 [R]CN1C(=O)Nc2ccccc2C1=O.[R]C(=O)NCCCOC | |
| 8e49626130540113b761191a63db4d7a [R]NC(=O)c1ccc(CN2C(=O)Nc3ccccc3C2=O)cc1.[R]OC | |
| 850c39a875d8c91c949b76b532a2fbe1 [R]NC(=O)c1ccc(CN2C(=O)Nc3ccccc3C2=O)cc1 | |
| e9fad6f69c78c7152b6e96b019286557 [R]c1ccc(CN2C(=O)Nc3ccccc3C2=O)cc1 | |
| 3bac313e3a1407bc938d7d093e2750d4 [R]OC.[R]c1ccc(CN2C(=O)Nc3ccccc3C2=O)cc1 | |
| de8b70fbb034be06488813723d029b1e [R]CCCOC.[R]CN1C(=O)Nc2ccccc2C1=O | |
| 274ac33f2cbd3ae00a8b8a4cb1006172 [R]CCCOC.[R]N1C(=O)Nc2ccccc2C1=O | |
| 0abca81c6d847daf5669935c706fae95 [R]CN1C(=O)Nc2ccccc2C1=O.[R]OC | |
| bfdbde77200726474e128b2b2f8024fa [R]N1C(=O)Nc2ccccc2C1=O.[R]C(=O)NCCCOC | |
| fdb92e74d3c73ef3d422b61c91f042cf [R]NC(=O)c1ccccc1.[R]C(=O)NC | |
| ffb94dc07b57376c47726bbba123ad56 [R]c1ccccc1.[R]c2sccc2C(=O)NC | |
| 44d7b52846c08746361bd059da493136 [R]c1ccsc1NC(=O)c2ccccc2 | |
| 63a2ecd9be3b43c449e24dda1ca19d99 [R]C(=O)Nc1sccc1C(=O)NC | |
| 0ea9e766a97c9829e50cf56a9f9539b1 [R]C(=O)NC.[R]c1ccccc1 | |
| 3c7914ffcdbae59a402cceb80b40e56c [R]NC(=O)C1=COCCO1.[R]C(=O)OC | |
| f37ba0471aa825e1b0dbbdbe8c2b39e7 [R]C(=O)Nc1sccc1C(=O)OC | |
| 55167b490a7cb21c8eb9fe300a9e33c8 [R]c1ccsc1NC(=O)C2=COCCO2 | |
| 877d1b74bfe6e370cc7caa8d7aa6bef4 [R]C1=COCCO1.[R]c2sccc2C(=O)OC | |
| 22d4b8440aebd4cf263d0e605ffdcdc2 [R]C(=O)OC.[R]C1=COCCO1 | |
| 67f09a861f61517138ddaa8875f0df3b [R]c1cccc2\C(=N\O)\c3ccccc3c12 |
This file contains bidirectional Unicode text that may be interpreted or compiled differently than what appears below. To review, open the file in an editor that reveals hidden Unicode characters.
Learn more about bidirectional Unicode characters
| = Compound Structure Network | |
| Pierre Ducrot <[email protected]> | |
| v1.0, 3-May-2015 | |
| :neo4j-version: 2.2.0 | |
| :author: Pierre Ducrot | |
| :twitter: ducrot_pierre | |
| :tags: science, cheminformatics, molecular modeling | |
| == Domain | |
| Medicinal Chemistry | |
| Pharmaceutical research use biological data and compound structures to design new drugs. The proposed network shows how to store chemical structures into neo4j, as well as compound scaffolds, fragments, pharmacophore patterns, biological data (e.g. vitro and vivo pharmacology, ADME, toxicity) and physico-chemical properties (e.g. solubility, logP, logD, pKa). Compounds are linked to biological and physico-chemical properties by their measurements, linked to other compounds using precomputed similarity measurements and linked to scaffolds and fragments by substructure. | |
| image::data:image/svg+xml;base64,<?xml version="1.0" encoding="UTF-8" standalone="no"?>
<!DOCTYPE svg PUBLIC "-//W3C//DTD SVG 1.1//EN"
 "http://www.w3.org/Graphics/SVG/1.1/DTD/svg11.dtd">
<!-- Generated by graphviz version 2.36.0 (20140111.2315)
 -->
<!-- Title: G Pages: 1 -->
<svg width="620pt" height="383pt"
 viewBox="0.00 0.00 620.00 383.00" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g id="graph0" class="graph" transform="scale(1 1) rotate(0) translate(4 379)">
<title>G</title>
<polygon fill="White" stroke="none" points="-4,4 -4,-379 616,-379 616,4 -4,4"/>
<!-- Molecule -->
<g id="node1" class="node"><title>Molecule</title>
<ellipse fill="#d7191c" stroke="#f4a582" stroke-width="2" cx="42" cy="-191" rx="41.7203" ry="41.7203"/>
<text text-anchor="middle" x="42" y="-187.9" font-family="Helvetica,sans-Serif" font-size="12.00" fill="White">:Molecule</text>
</g>
<!-- Target -->
<g id="node2" class="node"><title>Target</title>
<ellipse fill="#1c6ac1" stroke="#abd9e9" stroke-width="2" cx="416" cy="-221" rx="33.7152" ry="33.7152"/>
<text text-anchor="middle" x="416" y="-217.9" font-family="Helvetica,sans-Serif" font-size="12.00" fill="White">:Target</text>
</g>
<!-- Molecule&#45;&gt;Target -->
<g id="edge1" class="edge"><title>Molecule&#45;&gt;Target</title>
<path fill="none" stroke="#1c6ac1" stroke-width="3" d="M82.5903,-201.424C89.0608,-203.024 95.7055,-204.606 102,-206 207.334,-229.33 236.156,-228.035 344,-225 353.056,-224.745 362.754,-224.308 371.983,-223.813"/>
<polygon fill="#1c6ac1" stroke="#1c6ac1" stroke-width="3" points="372.356,-227.298 382.142,-223.238 371.96,-220.309 372.356,-227.298"/>
<text text-anchor="middle" x="225" y="-230" font-family="Times,serif" font-size="10.00" fill="#1c6ac1">:isActiveOn</text>
</g>
<!-- Framework -->
<g id="node3" class="node"><title>Framework</title>
<ellipse fill="#ff9900" stroke="#ff99b2" stroke-width="2" cx="225" cy="-326" rx="49.4952" ry="49.4952"/>
<text text-anchor="middle" x="225" y="-322.9" font-family="Helvetica,sans-Serif" font-size="12.00" fill="White">:Framework</text>
</g>
<!-- Molecule&#45;&gt;Framework -->
<g id="edge2" class="edge"><title>Molecule&#45;&gt;Framework</title>
<path fill="none" stroke="#ff9900" stroke-width="3" d="M66.7112,-224.917C76.6417,-237.569 88.9179,-251.415 102,-262 122.337,-278.455 147.566,-292.532 169.794,-303.259"/>
<polygon fill="#ff9900" stroke="#ff9900" stroke-width="3" points="168.576,-306.554 179.114,-307.649 171.559,-300.221 168.576,-306.554"/>
<text text-anchor="middle" x="130" y="-299" font-family="Times,serif" font-size="10.00" fill="#ff9900">:hasScaffold</text>
</g>
<!-- Fragment -->
<g id="node6" class="node"><title>Fragment</title>
<ellipse fill="#008837" stroke="#a6dba0" stroke-width="2" cx="225" cy="-108" rx="43.9143" ry="43.9143"/>
<text text-anchor="middle" x="225" y="-104.9" font-family="Helvetica,sans-Serif" font-size="12.00" fill="White">:Fragment</text>
</g>
<!-- Molecule&#45;&gt;Fragment -->
<g id="edge5" class="edge"><title>Molecule&#45;&gt;Fragment</title>
<path fill="none" stroke="#008837" stroke-width="3" d="M80.5033,-173.802C108.067,-161.163 145.757,-143.88 175.593,-130.198"/>
<polygon fill="#008837" stroke="#008837" stroke-width="3" points="177.351,-133.242 184.982,-125.892 174.433,-126.879 177.351,-133.242"/>
<text text-anchor="middle" x="130" y="-165" font-family="Times,serif" font-size="10.00" fill="#008837">:hasFragment</text>
</g>
<!-- Antifragment -->
<g id="node7" class="node"><title>Antifragment</title>
<ellipse fill="#008837" stroke="#a6dba0" stroke-width="2" cx="416" cy="-54" rx="54.3439" ry="54.3439"/>
<text text-anchor="middle" x="416" y="-50.9" font-family="Helvetica,sans-Serif" font-size="12.00" fill="White">:Antifragment</text>
</g>
<!-- Molecule&#45;&gt;Antifragment -->
<g id="edge6" class="edge"><title>Molecule&#45;&gt;Antifragment</title>
<path fill="none" stroke="#008837" stroke-width="3" d="M63.2213,-154.912C85.5606,-119.149 125.196,-66.5463 176,-44 232.288,-19.0201 303.555,-26.3338 353.564,-36.911"/>
<polygon fill="#008837" stroke="#008837" stroke-width="3" points="353.065,-40.3853 363.585,-39.1341 354.581,-33.5514 353.065,-40.3853"/>
<text text-anchor="middle" x="225" y="-47" font-family="Times,serif" font-size="10.00" fill="#008837">:hasCSS</text>
</g>
<!-- Fingerprint -->
<g id="node8" class="node"><title>Fingerprint</title>
<ellipse fill="#d01c8b" stroke="#f1b6da" stroke-width="2" cx="225" cy="-191" rx="20.8602" ry="20.8602"/>
<text text-anchor="middle" x="225" y="-187.9" font-family="Helvetica,sans-Serif" font-size="12.00" fill="White">:Bit</text>
</g>
<!-- Molecule&#45;&gt;Fingerprint -->
<g id="edge8" class="edge"><title>Molecule&#45;&gt;Fingerprint</title>
<path fill="none" stroke="#d01c8b" stroke-width="3" d="M84.0717,-191C117.328,-191 163.429,-191 193.48,-191"/>
<polygon fill="#d01c8b" stroke="#d01c8b" stroke-width="3" points="193.772,-194.5 203.772,-191 193.772,-187.5 193.772,-194.5"/>
<text text-anchor="middle" x="130" y="-194" font-family="Times,serif" font-size="10.00" fill="#d01c8b">:hasBit</text>
</g>
<!-- Scaffold -->
<g id="node4" class="node"><title>Scaffold</title>
<ellipse fill="#ff9900" stroke="#ff99b2" stroke-width="2" cx="416" cy="-326" rx="38.5652" ry="38.5652"/>
<text text-anchor="middle" x="416" y="-322.9" font-family="Helvetica,sans-Serif" font-size="12.00" fill="White">:Scaffold</text>
</g>
<!-- Framework&#45;&gt;Scaffold -->
<g id="edge3" class="edge"><title>Framework&#45;&gt;Scaffold</title>
<path fill="none" stroke="#ff9900" stroke-width="3" d="M274.672,-326C303.019,-326 338.624,-326 366.876,-326"/>
<polygon fill="#ff9900" stroke="#ff9900" stroke-width="3" points="366.925,-329.5 376.925,-326 366.925,-322.5 366.925,-329.5"/>
<text text-anchor="middle" x="318" y="-329" font-family="Times,serif" font-size="10.00" fill="#ff9900">:hasScaffold</text>
</g>
<!-- Ring -->
<g id="node5" class="node"><title>Ring</title>
<ellipse fill="#ff9900" stroke="#ff99b2" stroke-width="2" cx="584" cy="-326" rx="27.9043" ry="27.9043"/>
<text text-anchor="middle" x="584" y="-322.9" font-family="Helvetica,sans-Serif" font-size="12.00" fill="White">:Ring</text>
</g>
<!-- Scaffold&#45;&gt;Ring -->
<g id="edge4" class="edge"><title>Scaffold&#45;&gt;Ring</title>
<path fill="none" stroke="#ff9900" stroke-width="3" d="M455.084,-326C482.378,-326 518.946,-326 545.993,-326"/>
<polygon fill="#ff9900" stroke="#ff9900" stroke-width="3" points="546.216,-329.5 556.216,-326 546.216,-322.5 546.216,-329.5"/>
<text text-anchor="middle" x="513" y="-329" font-family="Times,serif" font-size="10.00" fill="#ff9900">:hasScaffold</text>
</g>
<!-- Fragment&#45;&gt;Antifragment -->
<g id="edge7" class="edge"><title>Fragment&#45;&gt;Antifragment</title>
<path fill="none" stroke="#008837" stroke-width="3" d="M267.477,-96.1495C292.749,-88.9287 325.503,-79.5707 353.725,-71.5071"/>
<polygon fill="#008837" stroke="#008837" stroke-width="3" points="354.846,-74.8271 363.499,-68.7145 352.922,-68.0964 354.846,-74.8271"/>
<text text-anchor="middle" x="318" y="-92" font-family="Times,serif" font-size="10.00" fill="#008837">:hasCSS</text>
</g>
<!-- Fingerprint&#45;&gt;Target -->
<g id="edge9" class="edge"><title>Fingerprint&#45;&gt;Target</title>
<path fill="none" stroke="#1c6ac1" stroke-width="3" d="M245.869,-194.154C275.774,-198.901 333.055,-207.993 372.611,-214.272"/>
<polygon fill="#1c6ac1" stroke="#1c6ac1" stroke-width="3" points="372.084,-217.732 382.509,-215.843 373.181,-210.818 372.084,-217.732"/>
<text text-anchor="middle" x="318" y="-213" font-family="Times,serif" font-size="10.00" fill="#1c6ac1">:isRelatedTo</text>
</g>
</g>
</svg>
[] | |
| == Building the network | |
| Molecule may be stored in various format from SMILES string (http://www.daylight.com), InChI code, InChI_AuxInfo to CTAB. For the sake of this demo, we'll upload only the SMILES string as it is the shorter and less memory consuming. However, if one intend to build an web-based application, it may be useful to store de InChI_AuxInfo as well, which contains in addition the 2D-coordinates of the molecule. | |
| Data preparation for this demo has been performed with Pipeline Pilot (http://www.biovia.com) and could have been done with Knime (http://www.knime.org, open source). Compound structures and biological data were extracted from the PubChem Database (https://pubchem.ncbi.nlm.nih.gov). Preparation consists of computing the scaffold hierarchy of each molecule, keep parent/child relationship. Molecules are registered based on their InChiKey and named after their original PUBCHEM CID, scaffolds are registered based on their MD5 encoded canonical SMILES string and named after an index of type SCF0000001 to n. Molecules are recursively chopped up into fragments which are registered based on their MD5 encoded canonical SMILES string and indexed after an index of type FRG0000001. Compound Tanimoto similarity has been precomputed using three different fingerprints and recorded when greater than a specific cutoff value. | |
| image::data:image/png+xml;base64,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[] | |
| //hide | |
| //setup | |
| [source,cypher] | |
| ---- | |
| CREATE CONSTRAINT ON (t:Target) ASSERT t.Name IS UNIQUE; | |
| CREATE CONSTRAINT ON (m:Molecule) ASSERT m.Name IS UNIQUE; | |
| CREATE CONSTRAINT ON (m:Molecule) ASSERT m.InChIKey IS UNIQUE; | |
| CREATE CONSTRAINT ON (s:Scaffold) ASSERT s.Hashkey IS UNIQUE; | |
| CREATE INDEX ON :Scaffold(Size); | |
| CREATE INDEX ON :Scaffold(Name); | |
| CREATE INDEX ON :Fragment(Name); | |
| CREATE (:Target {Name: 'JNK3'}); | |
| LOAD CSV WITH HEADERS FROM 'https://gist.githubusercontent.com/pducrot/a26ab73f4bf49574ab38/raw/29e88ef47011e9df781ae34b3605c8bf808b3420/molecule.nodes' as line FIELDTERMINATOR '\t' CREATE (:Molecule {Name: line.CID, Key: line.InChIKey, Smiles: line.Canonical_Smiles}) RETURN count(*); | |
| LOAD CSV WITH HEADERS FROM 'https://gist.githubusercontent.com/pducrot/a26ab73f4bf49574ab38/raw/5b5fb2b05c796d8df0f073817f2768f6d61698ec/activity.edges' as line FIELDTERMINATOR '\t' MATCH (m:Molecule {Name: line.CID}), (t:Target {Name: line.Target}) WITH m, t, line CREATE (m) -[:isActiveOn {IC50: toFloat(line.IC50), pIC50: toFloat(line.pIC50)}]-> (t) RETURN count(*); | |
| LOAD CSV WITH HEADERS FROM 'https://gist.githubusercontent.com/pducrot/a26ab73f4bf49574ab38/raw/fac7a5c644b4b7e673a2e0f47854cbb6780cec77/similarity.edges' as line FIELDTERMINATOR '\t' MATCH (m:Molecule {Name: line.CID}), (r:Molecule {Name: line.ClosestNames}) WITH m,r,line CREATE (m) -[s:isSimilarTo {Metric: line.Metric, Fingerprint: line.Type, Similarity: toFloat(line.ClosestSimilarities)}]-> (r) RETURN count(*); | |
| LOAD CSV WITH HEADERS FROM 'https://gist.githubusercontent.com/pducrot/a26ab73f4bf49574ab38/raw/8bda33c45589e5ac8076eb80cd72787cd7d240e6/scaffold.nodes' as line FIELDTERMINATOR '\t' CREATE (:Scaffold {Name: line.SID, Key: line.Hashkey, Smiles: line.Smiles, Size: line.Size}) RETURN count(*); | |
| LOAD CSV WITH HEADERS FROM 'https://gist.githubusercontent.com/pducrot/a26ab73f4bf49574ab38/raw/22fff325cc7ac1b1efae23b5c06d5aacce7258ba/scaffold.edges' as line FIELDTERMINATOR '\t' MATCH (m:Molecule {Name: line.ParentID}), (s:Scaffold {Key: line.ScaffoldID}) WITH m, s, line CREATE (m) -[:hasScaffold {Kind: line.Type}]-> (s) RETURN count(*); | |
| LOAD CSV WITH HEADERS FROM 'https://gist.githubusercontent.com/pducrot/a26ab73f4bf49574ab38/raw/22fff325cc7ac1b1efae23b5c06d5aacce7258ba/scaffold.edges' as line FIELDTERMINATOR '\t' MATCH (p:Scaffold {Key: line.ParentID}), (s:Scaffold {Key: line.ScaffoldID}) WITH p,s,line MERGE (p) -[:hasScaffold {Kind: line.Type}]-> (s) RETURN count(*); | |
| LOAD CSV WITH HEADERS FROM 'https://gist.githubusercontent.com/pducrot/a26ab73f4bf49574ab38/raw/968332d1aa06df75f91891b9e2a7770b67d93647/fragment.nodes' as line FIELDTERMINATOR '\t' CREATE (:Fragment {Name: line.FID, Key: line.Hashkey, Smiles: line.Smiles, Size: line.Size}) RETURN count(*); | |
| LOAD CSV WITH HEADERS FROM 'https://gist.githubusercontent.com/pducrot/a26ab73f4bf49574ab38/raw/874849dd15252dbb6cfb2df5c42223dd4619e37e/fragment.edges' as line FIELDTERMINATOR '\t' MATCH (m:Molecule {Name: line.CID}), (f:Fragment {Key: line.Hashkey}) WITH m,f,line CREATE (m) -[s:hasSubstructure {CSS: line.CSS}]-> (f) RETURN count(*); | |
| LOAD CSV WITH HEADERS FROM 'https://gist.githubusercontent.com/pducrot/a26ab73f4bf49574ab38/raw/8f9b6e3e43d58c6d27e28afb717baa40851659c8/antifragment.nodes' as line FIELDTERMINATOR '\t' CREATE (:Antifragment {Key: line.Hashkey, Smiles: line.Smiles}) RETURN count(*); | |
| LOAD CSV WITH HEADERS FROM 'https://gist.githubusercontent.com/pducrot/a26ab73f4bf49574ab38/raw/874849dd15252dbb6cfb2df5c42223dd4619e37e/fragment.edges' as line FIELDTERMINATOR '\t' MATCH (m:Molecule {Name: line.CID}), (a:Antifragment {Key: line.CSS}) WITH m,a,line CREATE (m) -[s:hasCSS]-> (a) RETURN count(*); | |
| LOAD CSV WITH HEADERS FROM 'https://gist.githubusercontent.com/pducrot/a26ab73f4bf49574ab38/raw/874849dd15252dbb6cfb2df5c42223dd4619e37e/fragment.edges' as line FIELDTERMINATOR '\t' MATCH (f:Fragment {Key: line.Hashkey}), (a:Antifragment {Key: line.CSS}) WITH f,a,line CREATE (f) -[s:hasCSS]-> (a) RETURN count(*); | |
| ---- | |
| == Network at a glance | |
| [source,cypher] | |
| ---- | |
| MATCH (s) -[r]-> (t) | |
| RETURN labels(s)[0] as Source, count(distinct s) as nSources, | |
| type(r) as Relationship, count(r) as nRelationship, | |
| labels(t)[0] as Target, count(distinct t) as nTarget | |
| ---- | |
| //table | |
| [source,cypher] | |
| ---- | |
| MATCH path = (m:Molecule {Name: "CID3240978"}) -[:isSimilarTo|hasScaffold*1..3]- (n) RETURN path; | |
| ---- | |
| //graph_result | |
| == Useful queries | |
| === Active compounds | |
| Retrieve acitvities of compounds bearing a specific scaffold. | |
| [source,cypher] | |
| ---- | |
| MATCH path = (:Scaffold {Name: "SCF0000072"}) <-[:hasScaffold*]- (m) -[a:isActiveOn]-> (t:Target) | |
| RETURN m.Name, t.Name, a.pIC50, a.IC50+' uM' as IC50 | |
| ORDER BY a.IC50 | |
| LIMIT 10; | |
| ---- | |
| //table | |
| Report activity mean and standard deviation. Note that pIC50 = log10(1/IC50) where IC50 is in molar (stored in micro-molar in the database) | |
| [source,cypher] | |
| ---- | |
| MATCH path = (s:Scaffold) <-[:hasScaffold*]- (m:Molecule) -[a:isActiveOn]-> (t:Target) | |
| RETURN s.Name, t.Name, count(m.Name) as N, avg(a.pIC50) as pIC50, stdev(a.pIC50) as pIC50_sd, | |
| avg(a.IC50)+' uM' as IC50, stdev(a.IC50) as IC50_sd | |
| ORDER BY pIC50 desc | |
| LIMIT 5; | |
| ---- | |
| //table | |
| == Scaffold structural relevance | |
| At deep levels, the scaffold hierarchy may return scaffolds that are very small as compared to the original compound structures and therefore not so relevant to return similar structures. There are several ways to assess the structural relevance of a scaffold, one may compute the mean similarity of connected compounds or compute the density of the subgraph from a scffold to the molecules, including similarity edges or score the scaffold based on its betweenness in the scaffold to molecules subgraph. | |
| Mean similiarity measurement is obtained either by summming the similarities from edges and dividing by the number of actual edges, or by the total number of possible edges (N*(N-)/2, with N is the number of molecule nodes). It is noteworthy that the former return the proper mean, but over estimate the similarity between all molecules since the similarity edges were filtered using a similarity cutoff value while building the network. Conversly, the latter under estimate the mean similarity since it assume missing similarity edges to be 0.It may however be seen as a similarity weighted density. | |
| [source,cypher] | |
| ---- | |
| MATCH (s:Scaffold) <-[:hasScaffold]- (m:Molecule) | |
| WITH s,m MATCH (m) -[r:isSimilarTo]- (n:Molecule) -[:hasScaffold]-> (s) | |
| WHERE id(m) < id(n) | |
| RETURN s.Name, (count(distinct m)+1) as Nmol, count(r) as N, avg(r.Similarity) as Similarity, stdev(r.Similarity) as sd, | |
| toFloat(sum(r.Similarity))/((count(distinct m)+1)*(count(distinct m))/2) as WeightedDensity | |
| ORDER BY Similarity DESC | |
| LIMIT 5 | |
| ---- | |
| //table | |
| Density is obtained similarely from the number of similarity relationships to maximum relationship ratio: | |
| [source,cypher] | |
| ---- | |
| MATCH (s:Scaffold) <-[:hasScaffold]- (m:Molecule) | |
| WITH s,m MATCH (m) -[r:isSimilarTo]- (n:Molecule) -[:hasScaffold]-> (s) | |
| WHERE id(m) < id(n) | |
| RETURN s.Name, toFloat(count(r))/((count(distinct m)+1)*(count(distinct m))/2) as Density | |
| ORDER BY Density DESC | |
| LIMIT 5 | |
| ---- | |
| //table | |
| Betweenness cannot - to my knowledge - be calsulated using cypher, it corresponds to the number of times a node is on the shortest path between any other node pairs to the total number of paths between the latters. It is however possible to compute betweenness with R using the RNeo4j package (https://github.com/nicolewhite/RNeo4j). See picture below, node size is proportional to (log(betweenness+1)+1)*3. | |
| image::data:image/png+xml;base64,iVBORw0KGgoAAAANSUhEUgAAAqUAAAHsCAYAAADrZ9QLAAAD8GlDQ1BJQ0MgUHJvZmlsZQAAOI2NVd1v21QUP4lvXKQWP6Cxjg4Vi69VU1u5GxqtxgZJk6XpQhq5zdgqpMl1bhpT1za2021Vn/YCbwz4A4CyBx6QeEIaDMT2su0BtElTQRXVJKQ9dNpAaJP2gqpwrq9Tu13GuJGvfznndz7v0TVAx1ea45hJGWDe8l01n5GPn5iWO1YhCc9BJ/RAp6Z7TrpcLgIuxoVH1sNfIcHeNwfa6/9zdVappwMknkJsVz19HvFpgJSpO64PIN5G+fAp30Hc8TziHS4miFhheJbjLMMzHB8POFPqKGKWi6TXtSriJcT9MzH5bAzzHIK1I08t6hq6zHpRdu2aYdJYuk9Q/881bzZa8Xrx6fLmJo/iu4/VXnfH1BB/rmu5ScQvI77m+BkmfxXxvcZcJY14L0DymZp7pML5yTcW61PvIN6JuGr4halQvmjNlCa4bXJ5zj6qhpxrujeKPYMXEd+q00KR5yNAlWZzrF+Ie+uNsdC/MO4tTOZafhbroyXuR3Df08bLiHsQf+ja6gTPWVimZl7l/oUrjl8OcxDWLbNU5D6JRL2gxkDu16fGuC054OMhclsyXTOOFEL+kmMGs4i5kfNuQ62EnBuam8tzP+Q+tSqhz9SuqpZlvR1EfBiOJTSgYMMM7jpYsAEyqJCHDL4dcFFTAwNMlFDUUpQYiadhDmXteeWAw3HEmA2s15k1RmnP4RHuhBybdBOF7MfnICmSQ2SYjIBM3iRvkcMki9IRcnDTthyLz2Ld2fTzPjTQK+Mdg8y5nkZfFO+se9LQr3/09xZr+5GcaSufeAfAww60mAPx+q8u/bAr8rFCLrx7s+vqEkw8qb+p26n11Aruq6m1iJH6PbWGv1VIY25mkNE8PkaQhxfLIF7DZXx80HD/A3l2jLclYs061xNpWCfoB6WHJTjbH0mV35Q/lRXlC+W8cndbl9t2SfhU+Fb4UfhO+F74GWThknBZ+Em4InwjXIyd1ePnY/Psg3pb1TJNu15TMKWMtFt6ScpKL0ivSMXIn9QtDUlj0h7U7N48t3i8eC0GnMC91dX2sTivgloDTgUVeEGHLTizbf5Da9JLhkhh29QOs1luMcScmBXTIIt7xRFxSBxnuJWfuAd1I7jntkyd/pgKaIwVr3MgmDo2q8x6IdB5QH162mcX7ajtnHGN2bov71OU1+U0fqqoXLD0wX5ZM005UHmySz3qLtDqILDvIL+iH6jB9y2x83ok898GOPQX3lk3Itl0A+BrD6D7tUjWh3fis58BXDigN9yF8M5PJH4B8Gr79/F/XRm8m241mw/wvur4BGDj42bzn+Vmc+NL9L8GcMn8F1kAcXgSteGGAABAAElEQVR4Ae3dB5xeVZ3/8d+UTEkvk2Qy6b33QkinCgorKizyBwXRRf6i7qq7Fvz/XVdddBVFXUSRRRTxryiW1aUoYEICSUgjHRJIzySTOumZPv/7vfgkk8mU55mn3Pa5+5qdmee599xz3ucx/Obcc34nq945jAMBBBBAAAEEEEAAAQ8Fsj28N7dGAAEEEEAAAQQQQMAVICjlg4AAAggggAACCCDguQBBqeddQAUQQAABBBBAAAEECEr5DCCAAAIIIIAAAgh4LkBQ6nkXUAEEEEAAAQQQQAABglI+AwgggAACCCCAAAKeCxCUet4FVAABBBBAAAEEEECAoJTPAAIIIIAAAggggIDnAgSlnncBFUAAAQQQQAABBBAgKOUzgAACCCCAAAIIIOC5AEGp511ABRBAAAEEEEAAAQQISvkMIIAAAggggAACCHguQFDqeRdQAQQQQAABBBBAAAGCUj4DCCCAAAIIIIAAAp4LEJR63gVUAAEEEEAAAQQQQICglM8AAggggAACCCCAgOcCBKWedwEVQAABBBBAAAEEECAo5TOAAAIIIIAAAggg4LkAQannXUAFEEAAAQQQQAABBAhK+QwggAACCCCAAAIIeC5AUOp5F1ABBBBAAAEEEEAAAYJSPgMIIIAAAggggAACngsQlHreBVQAAQQQQAABBBBAgKCUzwACCCCAAAIIIICA5wIEpZ53ARVAAAEEEEAAAQQQICjlM4AAAggggAACCCDguQBBqeddQAUQQAABBBBAAAEECEr5DCCAAAIIIIAAAgh4LkBQ6nkXUAEEEEAAAQQQQAABglI+AwgggAACCCCAAAKeCxCUet4FVAABBBBAAAEEEECAoJTPAAIIIIAAAggggIDnAgSlnncBFUAAAQQQQAABBBAgKOUzgAACCCCAAAIIIOC5AEGp511ABRBAAAEEEEAAAQQISvkMIIAAAggggAACCHguQFDqeRdQAQQQQAABBBBAAAGCUj4DCCCAAAIIIIAAAp4LEJR63gVUAAEEEEAAAQQQQICglM8AAggggAACCCCAgOcCBKWedwEVQAABBBBAAAEEECAo5TOAAAIIIIAAAggg4LkAQannXUAFEEAAAQQQQAABBAhK+QwggAACCCCAAAIIeC5AUOp5F1ABBBBAAAEEEEAAAYJSPgMIIIAAAggggAACngsQlHreBVQAAQQQQAABBBBAgKCUzwACCCCAAAIIIICA5wIEpZ53ARVAAAEEEEAAAQQQICjlM4AAAggggAACCCDguQBBqeddQAUQQAABBBBAAAEECEr5DCCAAAIIIIAAAgh4LkBQ6nkXUAEEEEAAAQQQQAABglI+AwgggAACCCCAAAKeCxCUet4FVAABBBBAAAEEEECAoJTPAAIIIIAAAggggIDnAgSlnncBFUAAAQQQQAABBBAgKOUzgAACCCCAAAIIIOC5AEGp511ABRBAAAEEEEAAAQQISvkMIIAAAggggAACCHguQFDqeRdQAQQQQAABBBBAAAGCUj4DCCCAAAIIIIAAAp4LEJR63gVUAAEEEEAAAQQQQICglM8AAggggAACCCCAgOcCBKWedwEVQAABBBBAAAEEECAo5TOAAAIIIIAAAggg4LkAQannXUAFEEAAAQQQQAABBAhK+QwggAACCCCAAAIIeC5AUOp5F1ABBBBAAAEEEEAAAYJSPgMIIIAAAggggAACngsQlHreBVQAAQQQQAABBBBAgKCUzwACCCCAAAIIIICA5wIEpZ53ARVAAAEEEEAAAQQQICjlM4AAAggggAACCCDguQBBqeddQAUQQAABBBBAAAEECEr5DCCAAAIIIIAAAgh4LkBQ6nkXUAEEEEAAAQQQQAABglI+AwgggAACCCCAAAKeCxCUet4FVAABBBBAAAEEEECAoJTPAAIIIIAAAggggIDnAgSlnncBFUAAAQQQQAABBBAgKOUzgAACCCCAAAIIIOC5AEGp511ABRBAAAEEEEAAAQQISvkMIIAAAggggAACCHguQFDqeRdQAQQQQAABBBBAAAGCUj4DCCCAAAIIIIAAAp4LEJR63gVUAAEEEEAAAQQQQICglM8AAggggAACCCCAgOcCBKWedwEVQAABBBBAAAEEECAo5TOAAAIIIIAAAggg4LkAQannXUAFEEAAAQQQQAABBAhK+QwggAACCCCAAAIIeC5AUOp5F1ABBBBAAAEEEEAAAYJSPgMIIIAAAggggAACngvkel4DKoAAAggg4GuB+vp627lzp61Zs8aOHD5sXbp2tUmTJtnw4cMtO5uxDV93HpVDIEACWc4/NvUBqi9VRQABBBDIoMDx48ftvs9+1rY//4LNOlxuvU6etPL27e3Vnt2t04zp9vVHHrEuXbpksEbcCgEEwipAUBrWnqVdCCCAQJICVVVVNnrgQLvn6HH7RFWtZTn/1/B4OKvOPmE1tmfPHuvbt2/Dt/gZAQQQSFiA5y4Jk3EBAgggEH6Buro6+/xH77brnNHRT1bVXRSQSuCj9dn2K8u1z99xhymA5UAAAQSSESAoTUaPaxFAAIGQCmzZssUOLFpk99e0PMPrvU5gWrxxsy1evDikEjQLAQQyJUBQmilp7oMAAggESGDVqlU2d/+BJkdIGzdjftlBW7lwYeOX+R0BBBBISICgNCEuTkYAAQSiIXDYmSfauzK+R/K9nND1yK7d0YChlQggkDYBgtK00VIwAgggEFyBTkVFdiLrwoVNzbXmpPNGpx7dm3ub1xFAAIG4BAhK42LiJAQQQCBaAuMmTLDVJcVxNXpll042bt68uM7lJAQQQKA5AYLS5mR4HQEEEIiwwLRp0+zoiOG2xOpaVNhp9bawT2+78sorWzyPNxFAAIHWBAhKWxPifQQQQCCCArm5uXbvg/9pX+pXbOuaCUy3OQHpnUVd7Bv/7xck0I/gZ4QmI5BqAbYZTbUo5SGAAAIhERgzZox989dP2t3vv8VuOHHK5h47YT2dtpU7X8s7FNqiAf3sug9+wAYPHhySFtMMBBDwUoCg1Et97o0AAgj4WOCks6Wovp5eucIWOTlLn33+eSvfv99Z1NTDJlxxhf3kne80JdlfuXKlzZ071woKCnzcGqqGAAJ+F2CbUb/3EPVDAAEEPBBQsKmE+MOGDbN+/fq1WIO33nrLysrKbNasWZadzaywFrF4EwEEmhXgX49maXgDAQQQiK7AG2+8YZ06dWo1IJWQAtfCwkJbt25ddMFoOQIIJC1AUJo0IQUggAAC4RI4fPiwlZaW2vjx4+Nu2KRJk9xH/du2bYv7Gk5EAAEEGgoQlDbU4GcEEEAg4gI1NTW2du1amzx5suXl5cWtkZOTYzNmzLDt27fboUOH4r6OExFAAIGYAEFpTILvCCCAAAK2fv16Ky4utiJnR6dEDy10mjp1qr322mt26tSpRC/nfAQQiLgAQWnEPwA0HwEEEIgJ6JH9iRMnbPTo0bGXEv7evXt3GzVqlLsiv7q6OuHruQABBKIrQFAa3b6n5QgggMA5gbNnz9qmTZtsypQppkfxyRwDBgywnj17uiOmyZTDtQggEC0BgtJo9TetRQABBJoU0CP3IUOGWOfOnZt8P9EXlXi/trbWXn/99UQv5XwEEIioAEFpRDueZiOAAAIxgdiK+aFDh8ZeSvq78pVqfum+ffvclfxJF0gBCCAQegGC0tB3MQ1EAAEEmhfQHFIlv1dKp6ysrOZPbMM7Wr2vFfmaFnDs2LE2lMAlCCAQJQGC0ij1Nm1FAAEEGgho1yY9th87dqy1b9++wTup+1EJ+CdMmGCrVq2yioqK1BVMSQggEDoBgtLQdSkNQgABBOIT0HzPjh07xrVrU3wlNn2WUkwNHDjQVq9ebQqEORBAAIGmBAhKm1LhNQQQQCDkAtq1af/+/e4oZiaaOnz4cMvPz3fzoGbiftwDAQSCJ0BQGrw+o8YIIIBAUgLKH6rH9ppH2q5du6TKSuRi7RJ1/Phxd9enRK7jXHN32Xrqqads69atcCAQWgGC0tB2LQ1DAAEEmhbQrk0lJSVt2rWp6RLjezW2FalW+2ukliM+gd/9+td2++VX2J5/uNtGjhxpi/761/gu5CwEAiaQVe8cAasz1UUAgYgLnD592s6cOWPaPSjZRO9Ro9SuTVptP3fuXFPaJi+Oo0ePugufZs+ebR06dPCiCoG6Z3GXLrbmRIX1six7y+rtSzOn2K+XLQtUG6gsAvEI5MZzEucggAACXgsoddHPf/5r+8Uv/mplZcedgKqjE5CecIKrCfbxj9/iPor2uo5+v792bdq4caNdeumlngWkMmq4FemcOXMsN5f/FLX02ZnYs5d1PbHbPaW78//f2LO3pdN5D4HACvAvQWC7joojEB2BI0eO2N/93cecRTKz7NSp+5yGD/pb46ucOXaL7be/vc0eeOD/2B13vD86KG1oqeaRDhs2LGW7NrWhCucu0Vakml+qOk2fPv3c6/xwXkB/iOmPiFGXXWYfLf+93Xj0mH2xfb594nOfPX8SPyEQIgEe34eoM2kKAmEUUNL13r37WlXVd5zmfbSZJp52Rt9uswcfvNVuueXGZs6J9st6ZH/w4EF3lDTVSfLbKqv0UMuXLz83ctrWcsJ2XVVVlW3ZssXNjjBq1ChTAP/HP/7Rtm7YYGOnTLFrr702bE2mPQi4AgSlfBAQQMDXAvfe+w27//52Vl39mVbqedhZBPIRe+WVR61Hjx6tnButtzXipuBP80gLCwt91XhlAliyZIkp+NLiq6gfO3fudFfYy0KLmjKZHSHq9rTfewFvZrl7325qgAACARDQYqannnrZCUjviaO2RbZnzxX27LN/juPc6JzScNcmvwWk6gUFXdOmTXMfUyt4juqhxV+LFy+2ffv22cyZM23cuHEEpFH9MES43QSlEe58mo6A3wW049DZs6OcahbEVdUzZ6bZX/+6Ia5zo3LS5s2b3V2b+vbt69smd+7c2caPH28rVqywyspK39YzHRXT1qtr1qxxvzTfd9asWb6Y85uOtlImAq0JEJS2JsT7CCDgmYAWwlRVdU3g/t3syJHojrY1hlIu0LKyMps4cWLjt3z3e58+fdy5k6tWrYrEVqQawX7zzTftpZdectNiXeYsZmL6gu8+llQowwIEpRkG53YIIBC/gFIH5ecfif8CO2zFxd0SOD+8pzbctSkoKZdGjBhheXl57qP88PaM2YEDB2zRokVu9oF58+a5c0fJtxvmHqdt8QqQEipeKc5DAIGMC2jxS4cObzn3PeV8dWz1/p06LbUrr5zU6nlROEG7NumRfVFRUaCaq61IX3nlFdOCn0GDBgWq7q1V9tSpU27ArUf2mq7Qs2fP1i7hfQQiJcBIaaS6m8YiECyBgoIC++AHr7T27R+No+I7nSDsJefcQjf1URwXhPaUvXv32smTJ90V7UFrpEZ1lbdUe7yHZSvSmpoa0/xoBdu9evWy+fPnE5AG7YNJfTMiQEqojDBzEwQQaKuARpeuv/4uJ23QO6y29vZmitnjpIG6zZ5//nvOvLw+bgCgVd2jR492c2A2c1EoX1bGAqVY0q5NWkAU1EMBqRYAacen9u3bB7UZpj8QtNisd+/e7h8J+fn5gW0LFUcg3QIEpekWpnwEEEhaQCuyL7nkKifl0xQ7evQWp7yxzpfybR500uYstCFDfuPkMr3Lrrvu7aTi9fX1bmqdN954w115ruA0yAFaIoBLly515tUWOyZDErnMl+fqEf7u3btt9uzZzpayOb6sY3OV0qYP2o1Jh9I7de2ayIK95krldQTCLUBQGu7+pXUIhEZAu9z84Ac/tBdf3GQ7duxzVuVXO/Mlu9m73jXDPvCB99nAgQMvaqtWOCuo0SpnLZpSMvKOHVufm3pRQQF5IbZrk9IKheVYt26dk6e22s1lGoQ26XOqR/XaPUtzovv37x+EalNHBHwhQFDqi26gEggg0JqA5uW98MILdsUVVyScVFzB6fbt223btm3uKKJWefsxkXxrBi29H9u1Sau5NRc3LIf6btmyZe6CLf1R4ddD9dTIrv4AUiCqz1hQsh741ZR6RU+AoDR6fU6LEQikwK5du+zQoUNJjZhpxE2BqYKHfv36uYGDUhAF/aitrXV3A1Ig5Ock+W111uij5smOHTvW/aOireWk6zrNf9Wjev2hozqGeTQ+XYaUi4AECEr5HCCAQCAEXn75ZTeI1OrlZA/NUdWIVmlpqZt2aOjQoYEe1VJApMBtypQpydL49nptpLB8+XJfLeDSojItYtIo9ZgxY3wZMPu2Q6kYAk0IkBKqCRReQgABfwkovdHZs2dTlkZHK6C1+ESPulXuiy++6I6gasQxaIdGj7Vr04QJE4JW9YTq26VLFze358qVK90APKGLU3yyPidbtmxxR29VrwULFhCQptiY4qIpwEhpNPudViMQKAGNRmVnZ6ct76bSTmmlfnl5uTsaqzmBup/fD42OaptKJZwPWpL8ttqqn44ePWozZ870pI/27dvnjo5q4ZxGR8M0f7etfcJ1CKRKgKA0VZKUgwACaRFQeqfnn38+I/kqlcZHI2AKUrVy2u/zM7VPvHJ4KjiKyqHPg0ZLNX9TuyJl6tBnQrtkaV6y7quglAMBBFIrQFCaWk9KQwCBFAvo0bRWzmcyzdGRI0fckVMFIAr4UjGPNcUsblJ2LdqaO3euJyOGqW5PIuUpE4PmGCsX64ABAxK5NOFz9RnQHyoaIdVCMqUey8rKSrgcLkAAgdYFCEpbN+IMBBDwUGDFihXWp08fT/I9HjhwwA1OlbhdCfh79OjhocT5W4dl16bzLUr8p9OnT7vbdk6bNi0to5Yakd2zZ4/b//r8aeRcu4RxIIBA+gQIStNnS8kIIJCkQEVFhS1atMiuuuoqT3f00Sp9jZbpUbmCUy1u8epQsKRdmxQohWHXpmQctcjrtddec0eLG+ed1Qin3u/UqZOboimR0U3NWVVGA+UZ1YK4qOwGlkxfcC0CqRAgKE2FImUggEBaBPR4WiNiflhZrmBQuVK1a5K2jNTImRf5KHV/5cXUQh8Oc3b32uGOaM6ZM8dNzfTkE0/Yst//wfY7rxdlZdvx+lqrb9/BLnnH1fa+O+9084g256Y/grSQSsGs8o2WlJQ0dyqvI4BAGgQIStOASpEIIJAagYULF9qkSZOsW7duqSkwBaVo5x4FQgqYNddUuww1HqVLwW2aLEK5Ol999dUmRwabvCAiL65du9bWrlljv3/gu3bVjl02//RZG23nsyectHp72ers8f597ZpPftzu+NSnLhh5b7jj16BBg2zYsGEXvB8RRpqJgOcCBKWedwEVQACBpgT0CFX7nl922WVNve35a1psE9sdSqv0hw8fbsp/mq4j7Ls2JeP237/5jf3XPR+3hw4dsz7W/CKkaic4/WB+jh2bMN7+Z8lit780b3jTpk3uY36NjmqKBgcCCHgjQFDqjTt3RQCBVgQUkGo+oN/nTSpXqHaH0qKYwYMHu/Vty4KYrVu32sGDB91cqco5qkC34cpyzXHUPEnlJOU4L6BV+Nc6f7hsq8m27i0EpOevMPvnglwb/vnP2vRrr3Gnh2jeaM+ePRuews8IIOCBAEGpB+jcEgEEWhbQKOQLL7zgjpKmc/Sx5Vok9q52hlJwun//ftO2pQpQtWq/pUPJ+n/7y1/ac4/91DofPmLFZ85a9ypngU5Bnu0qLLB2TrqjG+75mE2/5BJT0Dp//nxWgDcA1efk1vkL7HNLV9iEBo/rG5zS5I91zojpHb26200/esje/e53Ry6lVpMovIiADwQISn3QCVQBAQQuFNCoo/KTTp8+/cI3AvCbkqxrpb6mH+iRvkY7m9odSqvGv/KRj9jMrdvs5lNnrV8To3xvOcHTY90728ZBA+37v37SDXYDQJCxKv7lL3+xRR+43b5ysDzhey535pj+5v3vs+85fxRwIICAPwRy/VENaoEAAgicF9i9e3dgAzCtyJ86dappUZJWcmveqRZD6XF8LC2Rpib8y/V/Zw+UHvjbgpym50EOcwLVfz960n5Tvt5dfKPV/w0f6Z8Xi+ZPy555xuYePOI0/vyipnglpjq2/7Fqtbt7lxdZFOKtJ+chECWBxP+XHCUd2ooAAhkXUGJ4ffXu3Tvj907lDZXL9BLnsbvmgCqY1B71Gv1VSqdrnfRF3zsXkLZ+15vqs+2Xlmv/fPPN7ghs61dE44y9r79hA9vY1HZOUNrLmSqh6RYcCCDgDwGCUn/0A7VAwBXQY9+HH37Efve730VWRAFcw1HFoENoj/TZs2e7Sfc1L/TL99xjD5+qsJEJju7daDm2YO0Ge+zBB4NOkrL6lztTJHo0Me0h3hsUOem9NK+XAwEE/CFAUOqPfqAWCNiGDRuc3WOm2D335Nstt9xrt976scipKEH93r17Q/mIWiO/SjeUv+l1u9YJMNty3FFRbS89/nNTGiMOsx5OloJDzrzbth6HnIVo+qOBAwEE/CFAUOqPfqAWCNinP/1Vq6n5g9XWftCqqt5w9vU+7M5HjBKNdtJR4BbWOX5LX3zR5u9ve0CZ54wKTjtS7ibQj9Lnorm2Dp48yd5sY1Ba4VxXltfO+vXr11zxvI4AAhkWICjNMDi3Q6A5gV69+l7wVnn5OtPIYZQOLXDq379/aJu80ZlXOr0uuT6dceyEbVq6NLRGiTTskquusiV92jb3eLkTlI6ZPcsKCgoSuSXnIoBAGgUIStOIS9EIJCLwhS982Dn9auc/kg8622q+12bMGGt9+vRJpIhAn6sk9NrTPcz7jR932tc1iTmQ6mBtuHrUmeLAYW4e26Pjx9oKJ71TIkeNE5D+14ASu+Mzn0nkMs5FAIE0CxCUphmY4hGIV0C7ymgl8COPdLWf//zD9uij37WlzojYiRMn4i0i0OeVlpZacXGx5eaGOFNdVpbVJtlLNc71Wdn80x1j/NQ3v2nfHNzfdibwGH9kTp1Nvv2DzhzucbFi+I4AAj4QCPG//j7QpQoIJCigoOy22247d5W2q1y+fLmbWkgphsJ8aNX9+PHjw9xE69arlx1zgqfiJEZLjzlC3UM8xSHRD8DEiRPt3l88YcNnzXJGTNvZ5BayGpxw7P+tS0d7xzuutM995SuJ3orzEUAgzQL8uZ1mYIpHIBkBPb7Xf3RfffXVUOenPHbsmNU56Xl69OiRDJfvr5189dW2LLdtK+9jjVveo6tNnjcv9ivfHYFpTj7YRx55xP59ygT7mrMD1mLncb4CUB2Vzvcdztfj7bLtjqEDbOgXPmsP/+pX7nv8PwQQ8JcA24z6qz+oDQJNCmiu5erVq23KlCnWs2fPJs8J8ovr16+3wsJCd1vOILejtbpv2rTJvnHd9fbozlJnPK/pXZxaKuOkE1zdPnKIPb58mXXt2rWlUyP1nnbO0vauGml/+umnbdkf/tu2rl1rlWdOW112jhU7u2ldesO77d033RTqOcuR6nQaG0oBgtJQdiuNCqOA9lJftWqVO3Ia9N2OGvaPRkiff/55mz9/fiRWQn/urrtsxqM/s3fXJR6UfqtDgXX56r/axz71qYaEkf5Z/7vQH2z6/OTl5UXagsYjEHQBHt8HvQepf2QElOR7xowZplHFffv2habdWtzVrVu3SASk6rR//PKX7Ynxo+3VBFeM/zKrzp4bOtBud4JajrcFampqbM2aNe4fagSkfCoQCL4AQWnw+5AWREhAj2xnzpxpegy8Z8+eULRcuUmjlMBcKa++7WwjO8eq7dk41+L/0pkP+eTk8faMk42hQ4cOoej3VDRi48aN1stZPKYvDgQQCL4AQWnw+5AWREygU6dONstZabxlyxbbuXNnoFt/9uxZO3nypJsKKtANSbDyQ4YMcbdT/eVlc+3zPbrYGmfUtN75v4ZHtfP7Muf1u4p72F+uXGCfuO8+AtIGQGVlZe7iv7FjxzZ4lR8RQCDIAswpDXLvUfdIC5w5c8ZNFzVgwAAbNmxYIC0UWFdXV0c2X2RlZaX9+dln7ZffecBOOwnxe9fWWXfn62BOth1ytsAcMWO6vefuu90/QlauXOnu0z5ixIhA9nUqK11RUWGLFy92p7Ow4CuVspSFgLcC5Cn11p+7I9BmAe0RrxHTZcuWWW1trY0cObLNZXlxobZQ1RQEzZON6pGfn29XOFtltu/Y0aZOnWoHDx6048ePu6mxlLO24aP6yZMnu4GY5t+GMQNDIp+Btc7K+kGDBpGBIBE0zkUgAAIEpQHoJKqIQHMC2rd79uzZ7oipAtMxY8Y0d6rvXj9y5IgpKOvcubPv6pbJCmmhl7IpKNjUV3OHrBS4KgPDPCdPaVT3bNeUFS1wGj58eHNUvI4AAgEVYE5pQDuOaiMQE9CqY42YKjXO5s2bTSOQQTi0wKk/OxOZ5kZqk4R4DmVgGDx4sLviPCj9HE+74j1HuUg15UOjxlnOlq0cCCAQLgGC0nD1J62JqID2i9eqfD361aNNvwcsmkeqR9V9naTmUT40N/L06dPuXNF4HTRCmJ2dbUoYH6VD+WyV/mnUqFEXTGuIkgFtRSDsAgSlYe9h2hcZAQWmlzjbLVZVVdmGDRvcbTv92vjS0lI3jU+7du38WsWM1Cv26F5BZiKHdvaS4aFDhxK5LNDnvvnmm+6UhYEDBwa6HVQeAQSaF0jsX8Lmy+EdBBDwgYCCm+nTp7uBqVZra3TJjweP7t/ulQMHDsT96L5hP2rKhgLT1157zZRWK+xHeXm57dq1y02SH/a20j4EoixAUBrl3qftoRRQYKoFMRqF1CNeLQrx03HixAk3DVTUV5BrRPvYsWNWVFTUpu7R/NKhQ4e6W2z69Y+PNjWs0UWxXZsmTJjgLoxr9Da/IoBAiAQISkPUmTQFgZiAFoFoJE3/QV++fLkbBMbe8/p71HZwas5bo6QKSHNycpo7pdXXFZRqVX6Y55dq8Z6clCKLAwEEwi1AUBru/qV1ERfQ6JLSDCmXqUbmvD40oqe5kKy6N9N80nhX3bfUb5MmTbJ9+/a5q/hbOi+I7ykzgebNsmtTEHuPOiOQuABBaeJmXIFAoAT0H3SNMi119k3Xam8vDwUZykuqxP9RPpRTVim8lJ802UPTNKZNm2br16837fIVlkO7XalNSv+kRXwcCCAQfgGC0vD3MS1EwLQ1pUYnFZh6GbjsdbbSZJTUTI/uNYKdqmBLW20qVZRSJoVlfum6detMK+01d5YDAQSiIUBQGo1+ppUIuItiNAdRgalyY2b60CitRgdT8cg603VP9f0SSZgf772VVF+7PGkOZtAPrbTX54Vdm4Lek9QfgcQECEoT8+JsBAItoJGnkSNHunNMtQo+k4f2uS8pKUlqYU8m65uue2kkUxsHpOLRfeM6an6pylbQG9RDI/natUkL9RLN3xrUNlNvBBB4W4CglE8CAhET0ONzzTPVqnylJMrUoaB0wIABmbqdb+9z+PBhd16tVs2n+tB0AKUD06NvL0bDk22PdiLTFASNkHbs2DHZ4rgeAQQCJkBQGrAOo7oIpEJAj9AnTpxoK1ascB+pp6LMlso4cuSIO+qluY9RP7TqPp3pjbp06eKOhq9evTpw80vfeustN7+upiJwIIBA9AQISqPX57QYAVdAj4/1iFQ7P6V7u0pGSd/+0GkkMB3zSRt/pAcNGuTuD79x48bGb/n29+PHj9uOHTtMUxA4EEAgmgIEpdHsd1qNgCugpOTallTbVWpFeDoOJfBXINavX790FB+oMrVdptJhFRYWpr3eGgnXCLVymPr9UIosjeyOGzeOXZv83lnUD4E0ChCUphGXohEIgoBS7syYMcPNCZmOAEZlKvjVfu1RP2SRjgVOTbnG5pdu2LDBTp061dQpvnlNGQP0OdRCOA4EEIiuAEFpdPueliNwTkBzPS+99FLbtGmT6VF7Kg9tK0pu0rdFM/HovmHfaaOC0aNH26pVq3w7v1TZAjRKr1FSDgQQiLYAQWm0+5/WI3BOQKudZ82aZVu3bnXn9p17I4kfNEKnFD+9evVKopRwXKo5kxq97NSpU0YbpIwHWvykEVO/Hdr6VpkCNLc5VRsJ+K2N1AcBBOIXICiN34ozEQi9QIcOHdzAVAtOtBI62SO2wCkrKyvZogJ/vVbdZ+rRfWOsCRMmmOazakctPx0KSDXXmF2b/NQr1AUB7wQISr2z584I+FJAi3A0YqoARknM23ooSbyCUh7dvy2Y6Uf3DfstJyfHzV+quZsnT55s+JZnP+uzoVF0bebAgQACCEiAoJTPAQIIXCSg7SoVmGqun+aZtuXQXEGNvOor6ocS2SsLgZd5WjVtYMyYMe4qd6129/JQMPr666+za5OXncC9EfChQJaTN6/eh/WiSggg4AMBBVLa+UmPV7VgpqnH8NquVI9htTuUzu/Ro4eNGDHCtMBJSfoZKTV3KoT2cvfDYh71lUaxJ0+e7MknTP/JWbp0qfvZGDJkiCd14KYIIOBPAYJSf/YLtULANwIKNJVgX6OnDQMZBTdf//qjzq5Q26yiYoqTdqirE+wUOCOjh5w8nOusW7dqu+++e+yqq66K/CKWl19+2Q3qFbB7fWiUVPXRrklebPuqucrarEHZHjgQQACBhgIEpQ01+BkBBJoU0MiaAlM9flYw88Uv/of98pebrbT04875M5yvdk1c97qz6v4hmz272h5//P7I7mV+9uxZW7x4sV199dVNjjQ3AZf2l5QV4ZVXXnEDQ6WNytShDAQaeZ83b15GNhDIVLu4DwIIpEaAOaWpcaQUBEItkJ2d7e78pEf1c+debw89dNwJSJ9w2jzb+WoqIBXHaDt48D/tj38c7QSn/dK+lanu6MdDC5y06r6pqQ9e1VfpvzSVQPlLNRKeiUMjtGvWrHHvm4kdrTLRJu6BAAKpFSAoTa0npSEQWgEFpo8//kcnsDjtrJq+32lnTlxtra39R6usfNRuueUzpgU/UTu8XHXfknXfvn2tZ8+e7k5eLZ2XqvfeeOMNN1+q7suBAAIINCVAUNqUCq8hgMBFAi+99JL99rcHnZG1ly96r7UX6ure5zy2nWI//vHjrZ0aqveVHF4LwBT8+fEYO3asuwXpzp0701o9zSFVntbx48en9T4UjgACwRYgKA12/1F7BDIioBXTX/3qo05goTmkbTtOn/6IPfzwc3b06NG2FRDAq5RSS7tZaZTZj4fqNXXqVDcfreZ7puOorq62tWvX2qRJk6xdu+ameqTjzpSJAAJBE/Dnv5RBU6S+CIRcQOmd3nyz0mllMiNdHZ05plPdhS4h5zrXPI0OFhcXn/vdjz8oj6x2fFq9enVa5pdqe9OSkhIrKiryY/OpEwII+EiAoNRHnUFVEPCrwIoVK5wRzrlJV6+8fK795S+rki4nCAVoYY9Ghb3aWjQRI+WT1YiuRjRTeWhXMC2OGzVqVCqLpSwEEAipAEFpSDuWZiGQSoGDB8uduYfdU1BkN2f70mg8vteje206kJubmwK39Beh3Z6Uvmr79u0puZnK0m5gym2rbU45EEAAgdYECEpbE+J9BBCw8nKtmu+UAokuzt7r0ViBH4RH9w07NDa/VMnttTgr2eO1116zoUOHuivuky2L6xFAIBoCBKXR6GdaiUBSAgMGFDmjXQeTKuPti8uc+YXhn1uozQYOHz7s+/mkjTu0ffv27vxS5S/VAqW2Htu2bTMtjlNQyoEAAgjEK0BQGq8U5yEQYYFBgwY6aY3eSlogN3ebTZw4MOly/F6AUiB16tTJ8vLy/F7Vi+qnhVlamNTW+aWaQ6rRVj2299OGARc1lBcQQMB3AsGY7OQ7NiqEQLQEpk+fbp07f8vKyiqchhe0ufF9+iyxyy+/p83XB+VCJcz3+6r7liy1MGnp0qWmEc/YaGdFRYUbqK53HssfdbIx1Dk7QfUYNMhGOHNRp02b5gbhGiHWY3vlP9WoKwcCCCCQiABBaSJanItARAW0LeStt15m9933U2d3prvbqLDE+vU7FInUQFrkNGLEiDY6eX9ZbH7pkiVLrKCgwF549ll76rvfs8FHy2162UEb5zyab2dZdsTq7bleRfbtrl3s6js/ZNPmzjWlmOrXr5/3jaAGCCAQOIEsZ95PfeBqTYURQCCjAholW7hwoX3qUw86idYfcO6daMB1xnkkfIv95Ccfc4MWjaiNHj3atzsdJYOruaSbN2+2efPmJVOML67duHGjfeGOO2z6m9vtf584bd2cQLSp44wTnD5WmGfPDupvDzsB7MCB4Z+i0ZQDryGAQHICBKXJ+XE1AqEX2LNnjxtkDR482FmFX2433HCv8xj/x067413Ecsq6dr3Dvv3t99qdd/4v10sr07ds2eLOuVRw2q1bt9A4KpDLz8+34cOHB7pNp06dsu5du9rj9Tl2Y13TwWjjBr5odXaNvb2D08SJExu/ze8IIIBAiwIEpS3y8CYC0RVQnsl169aZ9m/XFpGdO3d2MVavXmNXX32rkxheI6bXtAK01nmU+4B99rNz7BOf+IeLztVOUVu3bnWC1q42cuRId17iRScF7IUXXnjBZs6caR07dgxYzc9X98yZM3bX9dfb1IVL7BP1ia2HfcUJTL83caw99NyzgZ5Xe16DnxBAIFMCOV92jkzdjPsggEAwBHbt2uVuO6m5gVpFrZG/2FFS0sfe+9532IEDTzi79fzRSap/wkn/0+Fvb9c538ucr8XOTkY/tSlTnrHvf//DdvPN74tdfsH3Ll262CBnsUxlZaWtX7/eyWF60s1rGdQ90pXfU/NJFWAH+fjFT39quY/93P65sibhZgxwHvFXODtZvVRfa/Ouuirh67kAAQSiK8BIaXT7npYjcJHA6dOn3dFRTTXX49fWRvu0/eiLLy53vtY6eTnLnb3Ta515oj1s6tRhds01l9hll10W924+Nc5qbq323rlzp/Xt29d9/N0wGL6osj584Y033nBrFeRtNTVKevOMS+yxTc4IdjNzSFujr3XmmP6vIf3tu4sWWv/+/Vs7nfcRQAABV4CglA8CAgi4ic4VDOpRuuZCDhkyxDMVTRd48803TXNZNY9VKYmCslWnFoNpZFnTEYJ6LFu2zH71vpvs2/sPJ9WEBzoW2IBHfmQ3v//9SZXDxQggEB2BxCYLRceFliIQGQEtaHnllVecxUtlNtdJ6eNlQCp0JZxXnsv58+ebVv2/+OKL7n7stbW1vu4TOaqOQQ5IBbxu9Wqbsf9A0tbTT52x9U6QzoEAAgjEK0Ce0nilOA+BkAkoLdP27dvdR+aaA6m5nX46lBtVUwg0UqrH4nq0r3rqcbAfdwoK2l73zfV1ubP4zBFu7u24X1c+hfJ9++M+nxMRQAABglI+AwhEUEBbQWobSY1KKp+mAkC/HprXqh2DtIjo9ddfdwNpJabXVph+OhSUjnF2Nwr6Ue1Mn8hPQSO0wWptbeILpVJwa4pAAIGAChCUBrTjqDYCbRHQ6Kj2Jd+xY4cbQAVpEYoei1966aXOgqq3k9Nr5FQ5TouKitpCkdJrlD5LXz169EhpuV4U1tOZx3vIWaiU7HHEKaDIZ384JNsmrkcAgfQKEJSm15fSEfCNwPHjx919yTXyqPma2j4yiIeCUI3uamRSieo12qsRSi/ncmo+bp8+fXw5rSDRPh4xbpy9UNTdbjp8PNFLLzh/bX6eDbvkkgte4xcEEECgJQGC0pZ0eA+BEAhodFRzMvfu3esuIFK6pTAcCgKLi4vdVfqrVq1y85tq5LS1NFbpaLsCZM19DcOhqRLfcfayrzx8zHmM3/a5pcuKe9mXQrDVahj6lDYgEBQBVt8HpaeoJwJtEDiqJOYvveQ+Wl6wYIGb/7MNxfj2Ei14GjBggF1++eXuo/OlS5e6c2WVazNTh1JYaY5uz549M3XLtN5HGxpc8cEP2GMF7dp8n6ez6qz3vLmB30SgzQBciAACbRIgT2mb2LgIAX8LKDWRRkf37dtn48ePj8x2j7EE/Jozq/myw4YNu2A3qnT0mrZK1TzXKVOmpKN4T8o8ePCgffQd77AvrN1kUyyxsYsyZz7qB/sX2w/+/Jw759eTBnBTBBAIpABBaSC7jUoj0LyAAiTtWa9FN8r3GdQtO5tvYevvxBLwa8qCUl2lMwG/drXSdqx+ywbQulLLZyg7wyfedZ19f99BGx9nYLrHCUg/XNTFvvb739msOXNavgHvIoAAAo0ECEobgfArAkEV0Cjh5s2bTaNcyu8ZlsfJyfSHVsRrlyrtR6/AVDtEZWcnNvLX8P6HDh0yfWmerhZWyVi7OF3l7PGek5PT8NRQ/KwR5w9ccaV9dM8++/uaOstpYY7pM84j+58NG2wfeeA7du273hWK9tMIBBDIrABBaWa9uRsCaRFQILp+/Xrr3bu3+8g0KNtypgWjiUK125KmMyjXqXKcJpKAX0Hoz372pP3hD8uc6RBVTu7NYmdb1hwnCD3qTA04ZDNmDLdPf/pOmzBhQlIBbxPV9sVLmgLy4299yzb9959s5oGDNuNMhWkT1XZOgHrYGRldn9fOlpf0tu6zZ9td934hFLlafQFPJRCIoABBaQQ7nSaHR6C6utpNi1ReXu4GRX7I2eln3VgCfo2gaqW+VvA3d2g09Hvfe9h++MNnbdeuG62qarZzauMV9kqb9LKzgOwXdvXVJXb//fda9+7dmysy0K9r1PSJxx+3I1u2WoUT3Gvecg/Hb8SsS22m86g+DBsHBLqDqDwCIRAgKA1BJ9KEaAooN+aGDRvcwEoBVhgfH6erZzX6qZHT+vp6NzhtPNVBAeldd33efv/7Qjt69B+darQWaNY6c3efsNzcf7TS0h3WrZs22QzXIZM///nPTvB9NZ+1cHUtrUHANwLkKfVNV1ARBOIT0CIeBaNKQ6SckmEMgOKTaPtZCkL1FUvAr40ERo0adc7y5pv/wZ5+uo+TSuvLzk3iydWZY9XVtztfve3KKz9szz33cOjm9Cq9WKdOnQhI2/6x40oEEGhFgJHSVoB4GwE/CZSWltqmTZvcOZGaG8noaPK9o9FSrdLfsmWLu3hp5crX7ItffM3Ky3/gFB5PQHphHXJz/8duuOEZ+9Wv/jNU/aMFYxotVfDOgQACCKRDoO3LUNNRG8pEAIEmBSorK02ph9588027xNm6kcf1TTK16UUl4NfCJyXg15al99//Gycg/aJTVuIBqSpQU3OdvfxylSmRf5iOI0eOhHa+bJj6ibYgEGQBgtIg9x51j4TAnj17bNGiRe42mtrzXTvucKReQKmiNm163Un5dI1TeHJbsZaV3WX/+Z+/SX0lPSpRI6RaTBfWRVwesXJbBBBoJMCc0kYg/IqAXwS0QlxJ8DWHdNasWe58Pr/ULaz1+MMfltvJk3+fguZNstWrv+LO++3cuXMKyvO2CGUtUDtINeZtP3B3BMIuwEhp2HuY9gVSYOfOnbZkyRJTiqe5c+cSkGaoF9et2+LcaWoK7pZnFRVj3OkWKSjM8yK0SxijpJ53AxVAIPQCjJSGvotpYJAEzpw5Y9reUY9LNTrasWPHIFU/8HWtqtI/iXkpacfZs0WmYC4Mh1beazcsDgQQQCCdAgSl6dSlbAQSENi+fbs7sjZ8+HA3ANACHI5MC6TWPAx9GJtPOnVqKkaQM92f3A8BBIIkQFAapN6irqEQ0C5Mr7zyijs/b46zE462wNToqBba6FF9+/btQ9HOIDYiL6/aqXaF81WQdPULCw+dy3uadGEeFnD8+HHr0KGDszlAOw9rwa0RQCAKAgSlUehl2ugbAW3NOHr0dCcQneckZl9pEyf2sHvv/bib4mngwIG+qWdUKzJ58ignX+kap/mzkiSosoKCzaHI6alUUD169EjSg8sRQACB1gVY6NS6EWcgkDKBxx77mZOofYwdOPB9Z2X2Mmdnpu6mHKQEpCkjTqqg97znUmeV+bKkynj74jXOblvDQrFAjaA0BR8HikAAgbgECErjYuIkBFIjcOZMpbMV5VXnCqurK3GSrdec+50fvBV45zuvtQEDFjuV2JtEReqtuPgR++QnU5FaKolqpOBS7XZFftIUQFIEAgjEJUBQGhcTJyGQGoHrr7/GSkp+7BT2e2cO6UNOTsxv2Tvf+c7UFE4pSQso28GnP32js2/9g05Z9W0qLzf3ZzZvXqHNnDmzTdf76SLNJ9UcZ+10xYEAAgikWyDL+Uu4bf/yprtmlI9ASAXKysrsW996yHlM3NE+9rEPOQFQz5C2NLjNuueeL9pjj9U7837/3WlEIivyn3MCuPdZWdneUCxy2rZtm2Nw1saNGxfczqTmCCAQGAGC0sB0FRVFAIFMCWhB2s03/4M9/3yNM/f3Aee2rS30qXFWp//Wpk59yv7nf34UmoVBK1assH79+jmj+yWZouc+CCAQYQEe30e482k6Agg0LZCTk2NPPfUT++pX59iIER+y/PyfOCdubeLkcue1PzqB2212001L7POfv826dOnSxHnBe0kP0ZQ0n5X3wes7aoxAUAUYKQ1qz1FvBBDIiIB2ZXr88Sftj3981fbsOW21tb2tvj7HcnLKnR23Tjpzgmfarbde5z7i3rBhg7sb16RJkzJSt3Te5MSJE7ZmzRpbsGBBOm9D2QgggMA5AYLScxT8gAACCLQsoJFDBal6vN+1a1dnlX2xNdy1Sa8vXrzYRo4cGfhH3tphTBs7TJgwoWUU3kUAAQRSJEDy/BRBUgwCCIRfoHv37qav5g499td2nMuWLXOD1iDvzqX8pMwlba6neR0BBNIhwJzSdKhSJgIIRFagc+fOzjzUEfbaa685j/mDm9xEo8JFRUWR7UcajgACmRcgKM28OXdEAIGQCwwePNhyc3OdLUu3BLKlmk+qve7z8/MDWX8qjQACwRQgKA1mv1FrBBDwuYAWO+3evdv0GDxoB1uLBq3HqC8C4RAgKA1HP9IKBBDwmYBGGSdPnuw+xq+urvZZ7VquDo/uW/bhXQQQSI8AQWl6XCkVAQQQcHfr6tOnj61bty5QGsow0NKCrkA1hsoigEBgBAhKA9NVVBQBBIIoMHr0aDt9+rT7KD8I9VcaKM0nLSwsDEJ1qSMCCIRIgKA0RJ1JUxBAwH8C2dnZbpqo119/3c376b8aXlgjRkkv9OA3BBDInABBaeasuRMCCERUoGPHjqYRU+2QVFdX52sFthb1dfdQOQRCLUBQGurupXEIIOAXgQEDBpiS6WvE1M8HK+/93DvUDYFwCxCUhrt/aR0CCPhIYOLEibZ//347ePCgj2p1viqa+6rpBkHeiep8a/gJAQSCJkBQGrQeo74IIBBYAS0gmjJliq1du9YqKyt91w6NkrLq3nfdQoUQiIwAQWlkupqGIoCAHwQU9A0cONDNX+qH+jSsA4/uG2rwMwIIZFqAoDTT4twPAQQiLzBy5Eirra217du3+8qCoNRX3UFlEIicAEFp5LqcBiOAgB8EtNvTW2+9ZcePH/dDdezMmTNWX19vHTp08EV9qAQCCERPgKA0en1OixFAwAcCWkw0btw4N02URk29Phgl9boHuD8CCBCU8hlAAAEEPBIoKSmxbt262caNGz2qwfnbEpSet+AnBBDwRoCg1Bt37ooAAgi4AhotVUCoVFFeHgSlXupzbwQQkABBKZ8DBBBAwEOB3NxcN03U+vXr7ezZs57UpKKiwl14pZ2nOBBAAAGvBAhKvZLnvggggMDfBLp27WrDhg3zLE2U9rvv0aMH/YEAAgh4KkBQ6ik/N0cAAQTeFhg6dKhlZWXZ1q1bM07Co/uMk3NDBBBoQoCgtAkUXkIAAQS8ENBuTzt37rTy8vKM3v7o0aNWVFSU0XtyMwQQQKCxAEFpYxF+RwABBDwSyM/Pt4kTJ9rq1auturo6I7XQfNKqqipjPmlGuLkJAgi0IEBQ2gIObyGAAAKZFujdu7cVFxfbhg0bMnJrHt1nhJmbIIBAHAIEpXEgcQoCCCCQSYExY8bYiRMnbM+ePWm/rR7ds8gp7czcAAEE4hAgKI0DiVMQQACBTApkZ2fbtGnT7PXXX7fTp0+n9dZaed+9e/e03oPCEUAAgXgECErjUeIcBBBAIMMCmuM5YsQId35pXV1dWu5eWVlp+urcuXNayqdQBBBAIBEBgtJEtDgXAQQQyKDAoEGDrLCw0LZs2ZKWu2o+qUZJlYoqCMd/P/3fNvPG6VYyqtge/fmjQagydUQAgQQEsuqdI4HzORUBBBBAIIMCWhn/0ksv2aRJk6xnz54pvfPGjRutffv2NmTIkJSWm47C1q5da5MnT7aBpe0sq51Z+YJ8+8MP/mQLFixIx+0oEwEEPBBgpNQDdG6JAAIIxCuQl5fnBmMKyhSgpvII0nxSbcPa/9GOlluSZTk9s6zwyxW2cfPGVHJQFgIIeCxAUOpxB3B7BBBAoDUBJbbv37+/KTBN1aEAVzlKu3Tpkqoi01KO5rxql6tjx47Zqe9kW+3Reqs7VW9lf19jY0aNScs9KRQBBLwRICj1xp27IoAAAgkJaNGTArQdO3YkdF1zJysVVLdu3Xw7n1QpsRSEL1y40A2e77zzTvvOvd+zE5M6WudbRtiPHvuhXX755c01j9cRQCCAAswpDWCnUWUEEIimgNJDvfzyy3bppZcmvWJ+06ZNph2khg0b5htMLXEoKytzA+8zZ86YFnoNHDjQ2rVzJpFyIIBA6AVyQ99CGogAAgiERKBDhw42duxYW7Nmjc2bN8+Uz7Sth1bejx8/vq2Xp/Q6bam6e/du27lzpxUUFNjgwYOtT58+vh3FTWnjKQwBBM4JEJSeo+AHBBBAwP8C/fr1s4MHD5pGOtsaVCoI1Kir1/NJT5065Y6KlpaWmrZX1YYBXtfJ/58AaohAeAUISsPbt7QMAQRCKjBhwgQ3TZQedRcXFyfcyth80mRGWhO+aYMLFFRrbuzx48fdR/SXXXaZO5WgwSn8iAACERQgKI1gp9NkBBAItkBubq5NnTrVVqxYYV27dnUfeSfSIj2614r+TB41NTW2d+9e2759u6n+yo06ffr0pKYgZLL+3AsBBNIvQFCafmPugAACCKRcQMGo5l5qfqkWPiWyK5Pyk44bNy7ldWqqQC1Y0lxRzRlV8n9tAqBdpDgQQACBxgIEpY1F+B0BBBAIiIBWzh86dMi2bdsW9yp6jVhqPqmC2nQeCnw1KlpeXu6uoJ8/f767ZWo670nZCCAQbAGC0mD3H7VHAIEIC2h0dMqUKbZ48WL3cXxTgebZs2dNAaIWN2n1vg6dl475pHV1de4jeo2M1tbWuo/oNc0gJycnwr1E0xFAIF4B8pTGK8V5CCCAgE8FtOBp8+bNbpoozddUUPjU07+xp5f/yfYd3mvZvc2y87Os/oRZ7UGzsUPH2R3XfdiuvfbalOQA1c5Quqce0Svg1XzRTM9Z9WnXUC0EEEhAgKA0ASxORQABBPwqsGHDBvdR/l9XvGC/XfWknXh3qeXOqbN2g7MuqHJ9Zb1Vrq23vGe7Wd/Xh9m/3PZ5+7vr/+6Cc+L9RVt/ahX9gQMHTKmqNMc1NhobbxmchwACCMQECEpjEnxHAAEEAiywceNGu+3zt9ih92yz/FtrLLvgwmC0qaZVbaqz/B/2sr/ve7v9+xfua+qUi17TI3qNzGq+qLY9VSA6YMAAd0X9RSfzAgIIIJCAAEFpAlicigACCPhRYNeuXXbZ7fOs8mv7rHBOYrs81dfW2/6xZu+Y+U576tHfNjv/s6qqynQfPabv1KmTm19UCe8TWfXvRzvqhAAC/hEgKPVPX1ATBBBAIGEB7YY054ZZVv3QPiuYnlhA2vBmlZ/rYB/t/U/2fz79pYYv24kTJ9xH9Pv373e3/tTIaOfOnS84h18QQACBVAgQlKZCkTIQQAABDwT0KP3WT95ii6/7vRVe0/rj+paqqBHTnA8X20/v+pXNmjXLfUSv+aLaCnTQyyznIwAAHbpJREFUoEFuWqe8vLyWiuA9BBBAICkBUkIlxcfFCCCAgHcCr776qq08/YoVvCP5OmTlZNnpj+y3r/zoy/YvZz/nbvupVfTaxjQd6aOSrzElIIBA2ATa/qwnbBK0BwEEEAiYwINPft/OfvhAyuZ1aj7qWwWb3PLmzJljJSUlBKQB+0xQXQSCLEBQGuTeo+4IIBBZAT1WX7NtpRXMSu6xfWPA09cctGXrljZ+md8RQACBtAsQlKadmBsggAACqRfYtGmT1Y2ptKzs1AaleROybOnmJamvMCUigAACrQgQlLYCxNsIIICAHwW0Gr6i/8mUVy2nr9ne/XtTXi4FIoAAAq0JEJS2JsT7CCCAgA8FtKd9TWFVymuWXZhlFWcrUl4uBSKAAAKtCRCUtibE+wgggIAPBQoKCiznbLuU16yuwtmCND8/5eVSIAIIINCaAEFpa0K8jwACCPhQQKmaCko7prxmtaVmJcV9Ul4uBSKAAAKtCZCntDUh3kcAAQR8IqBk+YcPH3a/jh49arVrc8zq61OWEkrNrNpYbwM6D3L3tu/Zs6e7pahPmk81EEAg5AIEpSHvYJqHAALBFjh+/LgdOnTI/Tp27Jh16dLFioqK3F2XJj8zzZav+pOzvWjqVuB3+mtvu+Hq99qZM2dMyfl19OrVy/1SkJqT4wTCHAgggEAaBNhmNA2oFIkAAgi0VUDBoEZDFYjqe74zv1NBqAJCfW8YFC5cuNA+8uStlvWjI2293QXXVayqszHfn2fPPvaXc/dRPtSDBw/agQMHTAFy165dzwWpHTumfvrABRXiFwQQiJQAQWmkupvGIoCA3wRqamrOBaEKRPV7LADVdy1oau7Q4/z33f0eW3HbM1Y4L/klAlkf7WmP3PKELViwoMlbxuoaC1IVIMdGURUwsx1pk2y8iAACcQoQlMYJxWkIIIBAKgTqnTmgmg8aGw09efKkdevWzQ3uFNh17tw5odts27bN3vOZ6+zYN7ZZ3qi2P8Y/+t4cu3Pi3Xb/v34n7vur7hpBVZB64sSJc+3o3bu3tW/fPu5yOBEBBBCQAEEpnwMEEEAgzQJ6BB6bF7p37153JDQ2Gtq9e/ekRxhffuVlmztnrvVdnmsFlyQ+Ynr2vnY2YNFYe/nZpece2ydKolFUBadqpwLVdu3anRtF7dGjR9JtTLQ+nI8AAsETICgNXp9RYwQQ8LlAZWXluTmhGhHVocfcGgnVV15eXkpboIDwySeftK//v6/a0Q/vsMJ3Oyvyc1ofNa3eXW/ZD3W1SWWz7LHv/tSdL5qqimn+aSxI1c9qtwJxjaIWFham6jaUgwACIRIgKA1RZ9IUBBDwRqC2ttaOHDly7pF8RUWFaXRQgZiC0XQ+ytZ0gOXLl7ur8rXw6Os//Jq9WPoXO3lTqRXMybKcbhcHp1VvOEHrc+2tx6KB9skbP2VXzL/C3nrrLZs7d67l5qY+KUt1dfW5EVSNpCooj81FTcVIsTe9zl0RQCDVAgSlqRalPAQQCIXA7t27raqqyoYNG3ZRexQIxlI1aSS0vLzcHWWMPZLXHNFMHRs2bHCDvJEjR5675fr16+0Xf3rc/vTSn6ymS6Xl9K23+jxnVPRkrlW8WWOjB42xG+ffbDe95yaLraDftGmTnT592mbMmHGunHT9oNRWGkXVl6Y2xIJ3BaotLexKV30oFwEE/CFAUOqPfqAWCCDgI4FvPvgf9sjTPzTtLz8gb4gtfmaJabRPQVRsgZKCJwWh+tJoXzpGGFsj2bFjh+3atcvmzJlz0f21Mv/Pf/6zTZgwwR3F1SP+Dh06uEnxdX6nTp0uKF7na8RVbRk1atQF76XzFwX+sXmo8tWocuwxv4L7rKyLR3rTWR/KRgAB7wQISr2z584IIOBDgZUrV9qsBZfagPJsy8rLshMfbWfvL7zTrnvndeeCUI3seT2ipwBu7dq1bkDa1PQArfDX6KceyTc81qxZ47ajf//+DV92f1aAuHjxYhszZoyVlJRc9H66X9AItEZRYyv6lbNVAWrsUb9ytnIggEB4BVI/eSi8VrQMAQQiIKC5oQO/UGSWV+62NucG5/H3kiy7+uqrfdN6PfJWQDp9+vRm56tqSoFGPRsfSn6vqQdNBaWa66nH9xox1Uhq49HUxmWl+neNimp0VF8arVWQHAtQFWAr+FaAqsVSagejqKnuAcpDwFsBglJv/bk7Agj4TGDatGlWflel5Q6utbwxWZb7QA/7wDdu900tFahp+0+NZrY0d1UjpX379r2o3grm9u3bd9HrsReUJ3Xs2LG2YsUKmzdvnpvaKfZepr8rSFbwHAug1SYFqZpHq1HU2AiqvjfOaKDdrnTO/Pnzz82bzXT9uR8CCCQmQFCamBdnI4BAyAX0aH7D8k12+z0fsK4lXewf/uVumzJlii9arXmfml6gYLNfv34t1kkB3Pjx4y86R0GnEt2rrOZ2YFL5Gk1dvXq1XXLJJb4ZkdTIr75Gjx5tynCgKQxlZWW2ceNGN/CMBamf/tI/2Qv7nrXskbW267ojbhDep0+fiyx4AQEE/CXAnFJ/9Qe1QQABBJoV0CN75fhsuNK+qZP1eF+jqVdccUVTb9uiRYvcQLu13aNiqaYUBPr50FxUTbvQgqlly5bZp77xSeu5tdqt8qmf1dttOz5h93/5235uAnVDAAFHIPGtP2BDAAEEEMi4gPKIaoSzqRRVjSuj+aTKk9rcEZtX2tz7sdenTp3qjjKWlpbGXvLld80t1Qi3gmdlGyhecH4ubXb/ett/oPnpCr5sEJVCIKICBKUR7XiajQACwRHQI2qlf9IipJycnFYrrkf3CjybOzRCqlXurR3aKlSLqfR4XI/zg3BMnjzZhpx2Hu9/Ld9O/abO2v1rL/vSP305CFWnjghEXoCgNPIfAQAQQMDPAhodVTJ8BaTxpqFSUNrUyvtYO+MdKdX5CmA1+qj5pVpk5fdDQfszTzxn9xZ9wz6972v2zI/+0up0B7+3ifohEBUBFjpFpadpJwIIBE5Ai3m0Cl4Llrp06RJX/RU4VlZWusFkcxfEs9ip4bVaJNRw4VNzC6QaXuPlz3qc/7G7P+ZlFbg3Agi0QYCR0jagcQkCCCCQboHa2lo3IB04cKAlsnK8tUf3qrd2n1LOTy2IivfQ4ioFo5s3b473Es5DAAEEEhIgKE2Ii5MRQACBzAisW7fOfQQ/fPjwhG7YXNL8xoXoEX4880pj12n0UQuflIZp7969sZf5jgACCKRMgKA0ZZQUhAACCKRGYMuWLW7idyXIT/RobT5prDxNB0gkKNV1GmHV3FbtrpTotbH78h0BBBBoToCgtDkZXkcAAQQ8ENBuSxqJVPCX6NxNJcTX3M+WVt7HmqSgtC0r6jt27GiTJk2yVatWBWLhU6y9fEcAAf8LEJT6v4+oIQIIRERAj961habSMDXeNjMeAgWZ2q9eI5qtHQpcT5486e7s1Nq5jd/X3vPa+lOBqQJhDgQQQCAVAgSlqVCkDAQQQCBJgbNnz7pBnvJstrbTUnO30qP7bt26Nff2Ba9rFFaLnRSYtuXQwiflMWXhU1v0uAYBBJoSIChtSoXXEEAAgQwK1NTUuCvthw4datq/va1HvPNJY+Unkq80dk3D7wqgtbXn7t27G77MzwgggECbBAhK28TGRQgggEDqBF577TUrLi62IUOGJFVovCvvYzdpy2Kn2LX6Hlv49MYbb5juzYEAAggkI0BQmowe1yKAAAJJCujxd3V1tSWa+qnxbU+fPu0ujIp31yddr5FS7RiVzNGhQwebOHGiO/VAyf45EEAAgbYKEJS2VY7rEEAAgSQFtJ/99u3b3YVNia60b3zrRB/d6/qGOzs1Li+R37XwadCgQSx8SgSNcxFA4CIBgtKLSHgBAQQQSL+AgsitW7faggUL3AVDyd6xLUGp9onXSGeyo6Wqu0Z68/PzbePGjck2hesRQCCiAgSlEe14mo0AAt4JnDlzxh1V1A5JyvuZiiPR+aSxe6biEX6srClTppiC4127dsVe4jsCCCAQtwBBadxUnIgAAggkL6D5o6+++qoppVJRUVHyBTolqEyllFKO0kSPZBc7NbyfRl6V9F8LnxScciCAAAKJCBCUJqLFuQgggECSAqtXrzbNwRw4cGCSJZ2/XAGg8pNqf/pEj1QGpbq3cp9qxHTNmjXGwqdEe4PzEYi2AEFptPuf1iOAQAYFtFuTAsfRo0en9K5tfXSvSigoPXXqVEp3ZurZs6e78GnlypUpLTelaBSGAAK+EyAo9V2XUCEEEAijwM6dO+3IkSOmeaRtGdFsySQ2UtrSOc29p1X/qVrs1PAew4YNc8tVdgEOBBBAIB4BgtJ4lDgHAQQQSEJAux5ppb3mW8azL30it9Le88eOHYt7e9GmytZiJ5WR6kP5S0tLS02przgQQACB1gQISlsT4n0EEEAgCQE9GteOTdOmTXPnWyZRVJOXKp2TVvAnE+ymcgV+w0pq4dP06dPtrbfeckeJG77HzwgggEBjAYLSxiL8jgACCKRIQKviV6xYYWPGjLHu3bunqNQLi0nm0X2spFQvdoqVq+9a+DR58mTTAi9lCOBAAAEEmhMgKG1OhtcRQACBJAT0WF0Lffr06WP9+vVLoqSWL9Uipx49erR8UivvamenVC92anhLpb7SHFN51NbWNnyLnxFAAIFzAgSl5yj4AQEEEEidgFbaa3Q01SvtG9dQi6eUDiqZQ4udNAUgFTs7NVePIUOGuHlUt23b1twpvI4AAhEXICiN+AeA5iOAQOoFFHgdP37cHR1MfennS9TOUAooCwsLz7/Yxp80r1R1TucxYcIEKysrMwLTdCpTNgLBFSAoDW7fUXMEEPChwIEDB0xpkLTAJ5nFR/E0LRXzSWP30SP8dKzAj5Wv77GFTwpKlZGAAwEEEGgoQFDaUIOfEUAAgSQE9Ph73bp1buqnVIxetlaVZJLmNy5bUwDSPVKqe8pFmQiUkUAjvRwIIIBATICgNCbBdwQQQCAJgcrKSnel/bhx49xdkpIoKu5LUzGfNHazTp06uYudMrEQSXNtR4wY4Xpl4n6xNvIdAQT8LUBQ6u/+oXYIIBAAAQVWWlk+YMAAKykpyUiNlW5KI41K55SKIxOLnRrWc9CgQaZ5rGvXrm34Mj8jgECEBQhKI9z5NB0BBFIjoEf2sdG/1JTYeimxR/ep3LI0E4udGrZMC5+Uu1TJ9TkQQAABglI+AwgggEASAto+VCOWI0eOTKKUxC9N5SKn2N3TmUQ/do+G3zU6q/ml2ob04MGDDd/iZwQQiKAAQWkEO50mI4BAagT27dtnu3fvdlfaa2V5Jo90BaWZWOzU0KmgoMCmTp3qPsY/ffp0w7f4GQEEIiZAUBqxDqe5CCCQGgGlT9q4caO70j4/Pz81hcZZSn19vbtSPtVblyotlAJD7UaVyUPtGDVqFDs+ZRKdeyHgQ4FcH9aJKiGAAAK+FqioqHADqIkTJ5oCuUwfGs3UnvKpzoMaW+yk8pPdJSpREy0S032VKkrzZDUl4pJLLrG8vLxEi+J8BBAIqABBaUA7jmojgEBmBVasWGGP/PZhO3nolF0+8wq78sorrXfv3pmtxN/upkf3qR4ljTVEi500CpzpoFT3Vzqt2z/2QVu463nL7Wd2+N2nbM/2ve4q/Vj9+I4AAuEVICgNb9/SMgQQSJGAFuLc+JkbrObfDlnNFrNn/+8ztuPGXSkqPfFitPK+uLg48QvjuEJBqYJeLw5lMfjdn35rvXfXWFZ2lrUfbfbth+63r977NS+qwz0RQCDDAswpzTA4t0MAgeAJPPHUz636M4es/eXZ1vl/Z1vRPxba0qVLPWtIOhY5xRqT6RX4sfvqu6ZF9L2xhxuQ6vfcKXVWeqhUP3IggEAEBAhKI9DJNBEBBJIT6NW1t9UvOr+YqexHJ007IHlxxLbm1JzSdBxql+7hxU5LkyZNsl67+tuZH+bYmb/UWfa/Ftk/fehT6WgmZSKAgA8FspxVnPU+rBdVQgABBHwjUFVVZTMum2aHOx+wgoJ8u2bU9fbg13/gSf1KS0utrKzMTaOUrgosWbLExo4dm7Z5qy3VW9b3/tu9llVQbze942Y3u0FL5/MeAgiER4CgNDx9SUsQQCCNAvr7XXMe27Vr5wZsabxVi0Vv2LDBOnToYEOGDGnxvGTe1D06duxogwcPTqYYrkUAAQQSEmChU0JcnIwAAlEVUJoiPV72+tB80v79+6e1GppX6tVip7Q2jMIRQMDXAswp9XX3UDkEEEDgvEBNTY2b3D7duVG9XOx0vrX8hAACURMgKI1aj9NeBBAIrIBSQSl/qJLcp/PwcrFTOttF2Qgg4G+B9P7L5u+2UzsEEEAgUALpTAXVEEJBr0ZjtcMSBwIIIJApAYLSTElzHwQQQCBJAQWl6drJqXHVeITfWITfEUAg3QIEpekWpnwEEEAgBQJa/Z/J7T8VlDJSmoKOowgEEIhbgKA0bipORAABBLwTOHHihClhvlJSZeLQdqMEpZmQ5h4IIBATICiNSfAdAQQQ8LFApuaTxgi02Ons2bOe7OwUqwPfEUAgWgIEpdHqb1qLAAIBFcjkfFIRKS+rAlNGSwP6gaHaCARQgKA0gJ1GlRFAIHoCsXRQmWw5i50yqc29EECAoJTPAAIIIOBzAT1G10InbS+ayYN5pZnU5l4IIEBQymcAAQQQ8LlApueTxjgYKY1J8B0BBDIhQFCaCWXugQACCCQhkOn5pLGqxhY7aXtTDgQQQCDdAgSl6RamfAQQQCBJAc0nzVTS/IZV1WInjZYqHRUHAgggkG4BgtJ0C1M+AgggkISARilPnTrlbvuZRDFtvpRH+G2m40IEEEhQgKA0QTBORwABBDIlsHnzZvvBD35gmzZtMu1H78WhBVbPP/+8bdy40Yvbc08EEIiQQG6E2kpTEUAAgcAIrF692uZcNdu6fzvLjny+1spO7bNv/9sDGa1/aWmpXfW+K63z+3Ps7vH77bFf/sTueP+HMloHboYAAtERyHL+Cq6PTnNpKQIIIBAMgVnvnGm7vrjaCme/PUKafX2JvfTjpdanT5+MNWDW1Zfa9g+vtI4351jdmXrLfXc/e/kXy61Xr14ZqwM3QgCB6Ah48zwoOr60FAEEEGiTQMmgPpbV4F/oQ5uPurlK21RYGy/qNqCL5U/9W1DcPsvOVp11tx5tY3FchgACCLQo0OCfvBbP400EEEAAgQwKfPaOL1jprBo781/Zdvq6DnbLe2+xkpKSDNbA7EPv+ojV/XNXO/tSnZ34aK4NLBhsAwcOzGgduBkCCERHgMf30elrWooAAgET2LFjhy1cuNB9XH7dddd5UvsXXnzBfvf8Uzai/yi75657rF27dp7Ug5sigED4BQhKw9/HtBABBBBAAAEEEPC9AI/vfd9FVBABBBBAAAEEEAi/AEFp+PuYFiKAAAIIIIAAAr4XICj1fRdRQQQQQAABBBBAIPwCBKXh72NaiAACCCCAAAII+F6AoNT3XUQFEUAAAQQQQACB8AsQlIa/j2khAggggAACCCDgewGCUt93ERVEAAEEEEAAAQTCL0BQGv4+poUIIIAAAggggIDvBQhKfd9FVBABBBBAAAEEEAi/AEFp+PuYFiKAAAIIIIAAAr4XICj1fRdRQQQQQAABBBBAIPwCBKXh72NaiAACCCCAAAII+F6AoNT3XUQFEUAAAQQQQACB8AsQlIa/j2khAggggAACCCDgewGCUt93ERVEAAEEEEAAAQTCL0BQGv4+poUIIIAAAggggIDvBQhKfd9FVBABBBBAAAEEEAi/AEFp+PuYFiKAAAIIIIAAAr4XICj1fRdRQQQQQAABBBBAIPwCBKXh72NaiAACCCCAAAII+F6AoNT3XUQFEUAAAQQQQACB8AsQlIa/j2khAggggAACCCDgewGCUt93ERVEAAEEEEAAAQTCL0BQGv4+poUIIIAAAggggIDvBQhKfd9FVBABBBBAAAEEEAi/AEFp+PuYFiKAAAIIIIAAAr4XICj1fRdRQQQQQAABBBBAIPwCBKXh72NaiAACCCCAAAII+F6AoNT3XUQFEUAAAQQQQACB8AsQlIa/j2khAggggAACCCDgewGCUt93ERVEAAEEEEAAAQTCL0BQGv4+poUIIIAAAggggIDvBQhKfd9FVBABBBBAAAEEEAi/AEFp+PuYFiKAAAIIIIAAAr4XICj1fRdRQQQQQAABBBBAIPwCBKXh72NaiAACCCCAAAII+F6AoNT3XUQFEUAAAQQQQACB8AsQlIa/j2khAggggAACCCDgewGCUt93ERVEAAEEEEAAAQTCL0BQGv4+poUIIIAAAggggIDvBQhKfd9FVBABBBBAAAEEEAi/AEFp+PuYFiKAAAIIIIAAAr4XICj1fRdRQQQQQAABBBBAIPwCBKXh72NaiAACCCCAAAII+F6AoNT3XUQFEUAAAQQQQACB8AsQlIa/j2khAggggAACCCDgewGCUt93ERVEAAEEEEAAAQTCL0BQGv4+poUIIIAAAggggIDvBQhKfd9FVBABBBBAAAEEEAi/AEFp+PuYFiKAAAIIIIAAAr4XICj1fRdRQQQQQAABBBBAIPwCBKXh72NaiAACCCCAAAII+F6AoNT3XUQFEUAAAQQQQACB8AsQlIa/j2khAggggAACCCDgewGCUt93ERVEAAEEEEAAAQTCL0BQGv4+poUIIIAAAggggIDvBQhKfd9FVBABBBBAAAEEEAi/AEFp+PuYFiKAAAIIIIAAAr4XICj1fRdRQQQQQAABBBBAIPwCBKXh72NaiAACCCCAAAII+F6AoNT3XUQFEUAAAQQQQACB8AsQlIa/j2khAggggAACCCDgewGCUt93ERVEAAEEEEAAAQTCL0BQGv4+poUIIIAAAggggIDvBQhKfd9FVBABBBBAAAEEEAi/AEFp+PuYFiKAAAIIIIAAAr4XICj1fRdRQQQQQAABBBBAIPwCBKXh72NaiAACCCCAAAII+F6AoNT3XUQFEUAAAQQQQACB8AsQlIa/j2khAggggAACCCDgewGCUt93ERVEAAEEEEAAAQTCL0BQGv4+poUIIIAAAggggIDvBQhKfd9FVBABBBBAAAEEEAi/AEFp+PuYFiKAAAIIIIAAAr4XICj1fRdRQQQQQAABBBBAIPwCBKXh72NaiAACCCCAAAII+F6AoNT3XUQFEUAAAQQQQACB8AsQlIa/j2khAggggAACCCDgewGCUt93ERVEAAEEEEAAAQTCL0BQGv4+poUIIIAAAggggIDvBQhKfd9FVBABBBBAAAEEEAi/AEFp+PuYFiKAAAIIIIAAAr4XICj1fRdRQQQQQAABBBBAIPwCBKXh72NaiAACCCCAAAII+F6AoNT3XUQFEUAAAQQQQACB8AsQlIa/j2khAggggAACCCDgewGCUt93ERVEAAEEEEAAAQTCL0BQGv4+poUIIIAAAggggIDvBQhKfd9FVBABBBBAAAEEEAi/AEFp+PuYFiKAAAIIIIAAAr4XICj1fRdRQQQQQAABBBBAIPwCBKXh72NaiAACCCCAAAII+F6AoNT3XUQFEUAAAQQQQACB8AsQlIa/j2khAggggAACCCDgewGCUt93ERVEAAEEEEAAAQTCL0BQGv4+poUIIIAAAggggIDvBQhKfd9FVBABBBBAAAEEEAi/AEFp+PuYFiKAAAIIIIAAAr4XICj1fRdRQQQQQAABBBBAIPwCBKXh72NaiAACCCCAAAII+F6AoNT3XUQFEUAAAQQQQACB8AsQlIa/j2khAggggAACCCDgewGCUt93ERVEAAEEEEAAAQTCL0BQGv4+poUIIIAAAggggIDvBQhKfd9FVBABBBBAAAEEEAi/AEFp+PuYFiKAAAIIIIAAAr4XICj1fRdRQQQQQAABBBBAIPwCBKXh72NaiAACCCCAAAII+F6AoNT3XUQFEUAAAQQQQACB8AsQlIa/j2khAggggAACCCDgewGCUt93ERVEAAEEEEAAAQTCL0BQGv4+poUIIIAAAggggIDvBQhKfd9FVBABBBBAAAEEEAi/AEFp+PuYFiKAAAIIIIAAAr4XICj1fRdRQQQQQAABBBBAIPwCBKXh72NaiAACCCCAAAII+F6AoNT3XUQFEUAAAQQQQACB8Av8fxc/2TTfAjegAAAAAElFTkSuQmCC[] | |
This file contains bidirectional Unicode text that may be interpreted or compiled differently than what appears below. To review, open the file in an editor that reveals hidden Unicode characters.
Learn more about bidirectional Unicode characters
| CID Hashkey Smiles Size NumAttachments CSS | |
| CID0300385 40ff37b23ab7e50f673813778a2799c9 [R]c1ccccc1 6 1 88e8d646a409a3a47522d520919494fb | |
| CID0588806 c230b0bb3e580833ad3d825b9444a5c6 [R]C(=O)O 3 1 65093ae6ad910dc5d2bfcca22b047a91 | |
| CID0588806 db7c0f061564c242acd9b97c8c24b307 [R]CCS[R] 3 2 edafbcf9eb5a81147fd9dc796993b713 | |
| CID0588806 146a834c5468a9ff9932e1c930c59e4b [R]SCCC(=O)O 6 1 78e1cbc68f41a453f1787d2e7ea1ff91 | |
| CID0588806 5315ba718f2107f5017cb735faed8afd [R]CCC(=O)O 5 1 c6d9a93bad85b7b17d899129f4f2a4c1 | |
| CID0649913 2563b58ed23b5c3b1527083bc2ee56e6 [R]OC(=O)[R] 3 2 ee0eaeafc191199b3d61a9f8cc9e4667 | |
| CID0649913 2563b58ed23b5c3b1527083bc2ee56e6 [R]OC(=O)[R] 3 2 ecaedcc6503e4786f981123e996a4bd2 | |
| CID0649913 94ccb5b2d910c40f747b3924f0f20776 [R]NC(=O)[R] 3 2 ba3a3ff720459724dec665dbc26523c0 | |
| CID0649913 20909a7efda6e6dce692a77bc67c48c1 [R]c1ncc([R])c(N)n1 7 2 0b057900281846b77374ec9f863b365d | |
| CID0649913 6da339ab75c3d1d1427cad3f0e50c2ef [R]c1ccccc1[R] 6 2 c6dd30557c6ae093d154bd0a787743c0 | |
| CID0649913 adf2bc81282794ccff733cae00b8f17d [R]NC(=O)CS[R] 5 2 c6bfc33ab263f2fb82df21e0ae2a229b | |
| CID0649913 8b87e9872a00680ee0842d5d0a5f290d [R]C(=O)OCC 5 1 65dd0c693fca0b0908d38dd14a186bf7 | |
| CID0649913 8b87e9872a00680ee0842d5d0a5f290d [R]C(=O)OCC 5 1 66f54a0fe31e42dbf8bc2fcf84829d9c | |
| CID0649913 1c8f1342fd4b742c3c074bcc9632d320 [R]CC(=O)N[R] 4 2 8cae087819c9fb28d6882ab6bb4bc28f | |
| CID0649913 7a69ae1e38969cbfebdba1750950b49b [R]Sc1ncc([R])c(N)n1 8 2 a959cb036fb9e9b90d54319117d75839 | |
| CID0649913 f36abe78b05bc76ca84bf6dff89363a7 [R]OC(=O)c1cnc(S[R])nc1N 11 2 eedc196b125e908258cdb04c84d66941 | |
| CID0649913 65f74ac7eb94744fcf92898d5a6ce58f [R]CSc1ncc(C(=O)O[R])c(N)n1 12 2 c551af1b2e3ef66e4db999881f99be04 | |
| CID0649913 949962efe3c311f46962e09306044cd4 [R]CSc1ncc([R])c(N)n1 9 2 cd6c2e62f31991b8dbe1483e107d41ff | |
| CID0649913 bec1a087cc7232f64b3219b661c743b1 [R]NC(=O)CSc1ncc([R])c(N)n1 12 2 a43baab250aa7c8f81a1f0d0c2c3834e | |
| CID0649913 57e56a72e45f76bf30f0968313642982 [R]SCC(=O)Nc1ccccc1[R] 11 2 2c9ee8020069ef335094681ba3f14e9d | |
| CID0649913 9cb112b34ac4ec9f25de9f392a22d1c3 [R]OC(=O)c1ccccc1[R] 9 2 07ce6d1122153927dff02ed60732b6d9 | |
| CID0649913 fb069326d07744fb31b9532572b9326f [R]OC(=O)c1ccccc1NC(=O)[R] 12 2 bfbdf7b7b31f7c324bee053b178fa549 | |
| CID0649913 0332704df86c0fcfa4886d9e66ddd2d2 [R]c1ccccc1C(=O)OCC 11 1 f79fb5c648fc7adf05ef08d75b55c7e9 | |
| CID0649913 553ea46d0e7f241e9856a63f2960a5b0 [R]OC(=O)c1cnc([R])nc1N 10 2 aa79e096ed4cadb9e179a049fe80f1ad | |
| CID0649913 df48071ced2c344032f9c381cd154252 [R]c1ncc(C(=O)OCC)c(N)n1 12 1 b44b7a64c33c041db9903c4ae108d185 | |
| CID0649913 3c0fc5320fc164c8a112828272f6789f [R]C(=O)Nc1ccccc1[R] 9 2 6b24579b9d675215d1e1a5f09e4ecedd | |
| CID0649913 b4a241675c217a2e096a5c796f9ed5f5 [R]CC(=O)Nc1ccccc1[R] 10 2 588231cef0d378a1a31b038a466954a2 | |
| CID0651058 94ccb5b2d910c40f747b3924f0f20776 [R]NC(=O)[R] 3 2 a6953a8e72fb3dca47763fa8fa3e5811 | |
| CID0651058 94ccb5b2d910c40f747b3924f0f20776 [R]NC(=O)[R] 3 2 a84e97cafab1aff9e3818dfd35e78074 | |
| CID0651058 b99f4e0e3deb2a2cc8f77f23f41fa003 [R]C(=O)OC 4 1 711c85af99f5f16c1110341c555469ea | |
| CID0651058 4e11afcb7f861429aca649aaf168694c [R]C1CCN([R])CC1 6 2 267625b560a4f73a56ceda9a9485074d | |
| CID0651058 b577ac26aa3bd7b75f22800b57854927 [R]c1ccccc1C 7 1 500dce1259c314c9ed41233739b499c8 | |
| CID0651058 6da339ab75c3d1d1427cad3f0e50c2ef [R]c1ccccc1[R] 6 2 1502c8559c1b824a74ec5c9b649294a1 | |
| CID0651058 1c8f1342fd4b742c3c074bcc9632d320 [R]CC(=O)N[R] 4 2 69102fcea1fe2498d2308e4eefd95aa4 | |
| CID0651058 c6731fe86b6c867e456bad1ab01466a9 [R]N1CCC(CC1)NC(=O)[R] 9 2 f501991cfa0d12c3c155b1aad7eb1657 | |
| CID0651058 c8661c9810a5656c690ac61cae814a29 [R]CN1CCC(CC1)NC(=O)[R] 10 2 a6d6785ede665e41d6c50e8c362325de | |
| CID0651058 17933fa20cde572b6a227f2d230e2527 [R]NC(=O)c1ccccc1C 10 1 d78623bbf0b40377d3a086e964fe5482 | |
| CID0651058 1b07b84eacfc0b1cbd7ec7bc34816e5b [R]NC(=O)CN1CCC([R])CC1 10 2 3c83f145ab617751fc3fe970937e5103 | |
| CID0651058 b4a241675c217a2e096a5c796f9ed5f5 [R]CC(=O)Nc1ccccc1[R] 10 2 858188041bdcb1c44fb2043541a2d0c3 | |
| CID0651058 3c0fc5320fc164c8a112828272f6789f [R]C(=O)Nc1ccccc1[R] 9 2 3c82d44ce8e5c697a54d7bd13377a28e | |
| CID0651058 6e79403be5ab3ccde2532ab8e8bf0f12 [R]c1ccccc1C(=O)OC 10 1 5eb8ad9bd2adbd35a01df7efa3b33303 | |
| CID0651058 132bcc13879dceff1a97d1eeec5f47cd [R]CN1CCC([R])CC1 7 2 c28452affd8950fe9ff1a82b4dac3f2f | |
| CID0651323 94ccb5b2d910c40f747b3924f0f20776 [R]NC(=O)[R] 3 2 ae60defdb373cec7c847c85910056891 | |
| CID0651323 94ccb5b2d910c40f747b3924f0f20776 [R]NC(=O)[R] 3 2 e275df06d312401d55e6b6cbc52dfbd8 | |
| CID0651323 b99f4e0e3deb2a2cc8f77f23f41fa003 [R]C(=O)OC 4 1 8c4999a4bcb8e099d851b9377a69e214 | |
| CID0651323 4e11afcb7f861429aca649aaf168694c [R]C1CCN([R])CC1 6 2 b24037a65d1abef0425306bb97608e26 | |
| CID0651323 1182f5a434f5ca9647925fe1b4fefb96 [R]c1ccc(C)cc1 7 1 500dce1259c314c9ed41233739b499c8 | |
| CID0651323 6da339ab75c3d1d1427cad3f0e50c2ef [R]c1ccccc1[R] 6 2 59c1196c874be017ca0d639baac66919 | |
| CID0651323 1c8f1342fd4b742c3c074bcc9632d320 [R]CC(=O)N[R] 4 2 4fec4c8b530c2ceafaa8786afb54180d | |
| CID0651323 1b07b84eacfc0b1cbd7ec7bc34816e5b [R]NC(=O)CN1CCC([R])CC1 10 2 0f0f6e9b582f9e348b0d549b16de67e6 | |
| CID0651323 b4a241675c217a2e096a5c796f9ed5f5 [R]CC(=O)Nc1ccccc1[R] 10 2 8c648457889c8cddacffc3722fce3647 | |
| CID0651323 3c0fc5320fc164c8a112828272f6789f [R]C(=O)Nc1ccccc1[R] 9 2 720f1ca5c390832fbe1cbcca46a04c8a | |
| CID0651323 c6731fe86b6c867e456bad1ab01466a9 [R]N1CCC(CC1)NC(=O)[R] 9 2 7c604e61f6ca1595951320edf1aab8d3 | |
| CID0651323 c8661c9810a5656c690ac61cae814a29 [R]CN1CCC(CC1)NC(=O)[R] 10 2 e2dc435ed98a790030751d5825df7fc2 | |
| CID0651323 1faa2e983c36de3279bb18e398fa86a2 [R]NC(=O)c1ccc(C)cc1 10 1 d78623bbf0b40377d3a086e964fe5482 | |
| CID0651323 6e79403be5ab3ccde2532ab8e8bf0f12 [R]c1ccccc1C(=O)OC 10 1 e03c59d086ff4381a852e328479ec1f8 | |
| CID0651323 132bcc13879dceff1a97d1eeec5f47cd [R]CN1CCC([R])CC1 7 2 ca14e92b04e32e1687ea3a00386d195c | |
| CID0658703 aa16c7a7dca9b0411a328f76907dc84b [R]c1ccnc([R])c1[R] 6 3 2527c4b7eff04857a9793417b511f0d7 | |
| CID0658703 0c63224f62fb392c60f52371e7672c16 [R]c1cccnc1 6 1 10968916cee9e1465dfdf4689b4a86f5 | |
| CID0658703 40ff37b23ab7e50f673813778a2799c9 [R]c1ccccc1 6 1 a3fdf8a3a08d78a6d1b1181853b1f552 | |
| CID0658703 e74a1a643b405067f8373b79e66c039d [R]Nc1ccnc([R])c1[R] 7 3 473c69887f8dd4431bfd30aa13fab55e | |
| CID0658703 1a1e6a86ef0c63b3b0409aa29e78d1a4 [R]Nc1ccnc(N[R])c1[R] 8 3 987e85b799c4a879ccb9008aa8a54c65 | |
| CID0658703 4460bf4aaba15748e4445edcd996ceab [R]Nc1ccnc(N[R])c1C#N 10 2 87acf50911b12485147fd05d63b43bce | |
| CID0658703 4d6ad54abdb41d4f832a910e46569dd7 [R]CNc1ccnc(N[R])c1C#N 11 2 9aa6ab5a736a785e11da50e6fed1a217 | |
| CID0658703 0d2e6bdf3cf84f993c1556669a8544c7 [R]CNc1nccc(N[R])c1C#N 11 2 2006eea01aa4cf20431502be4ab5bcd1 | |
| CID0658703 d2edf82a8fcc978d8b34c5b6e50abffc [R]CNc1ccnc(N[R])c1[R] 9 3 89e0e9ebe03d639852af16bd27679b19 | |
| CID0658703 e062d547c9c1495b3ce8e812936736f8 [R]CNc1ccnc(NC[R])c1[R] 10 3 d1a1fc377d285a5b94c2892fba071fa5 | |
| CID0658703 558954ef7d9b51fcfc302179de2acbbe [R]CNc1nccc(N[R])c1[R] 9 3 5eb100b0715eb3f91a6d67b2ea40eb06 | |
| CID0658703 a0e97f9bbbdfd5de1b418675c51bf762 [R]Nc1ccnc([R])c1C#N 9 2 83efb1f127fbaf179321564bbea7faa0 | |
| CID0658703 4c1f3fa02e79cf35b070e23e05be9253 [R]CNc1ccnc([R])c1C#N 10 2 cc9cfd82792b809b2e990f0bcf8935ae | |
| CID0658703 f561e0a13470c42a9b08286f5b4587c7 [R]CNc1ccnc([R])c1[R] 8 3 aebc19065b10628d90410591752f5ecb | |
| CID0658703 67dc572f58faef87e6556cf88b49a22a [R]NCc1ccccc1 8 1 10425f9a81c93ca64ebd8458312fda5f | |
| CID0658703 1d83b4be805cc7a3dbd58238f66cb058 [R]Nc1nccc([R])c1[R] 7 3 ef4ce42f322cd50c929585a2122886e3 | |
| CID0658703 c428d1fe9d56e0a97362c311c35bf8b3 [R]Nc1nccc([R])c1C#N 9 2 a746a5a65eff9269a9f9e56613873d08 | |
| CID0658703 63d27fecb77a33792f3a4ff7c47f9535 [R]CNc1nccc([R])c1C#N 10 2 619e5e0582a86496e2e72e58832c77e2 | |
| CID0658703 b9ea5e09387bcf5fd5b00967dfe02be4 [R]CNc1nccc([R])c1[R] 8 3 057de0c876de3b8cd831dbc8b4e02c48 | |
| CID0658703 1b65af14022403f397fb173488a24d02 [R]NCc1cccnc1 8 1 bfbbdaa5dc82adbeb14ee5ffbbe1265c | |
| CID0658703 570a0482a263bc5a4dbe618cea60387e [R]c1ccnc([R])c1C#N 8 2 127cf3a9e42fe0a732399c1759f6c0ca | |
| CID0658703 c7792eac3fbab9da45cf28757e131cf5 [R]Cc1cccnc1 7 1 acb75e79bf9d84d7d2a22fa831d7894d | |
| CID0658703 644740ac60048143ee0e86d26953489e [R]Cc1ccccc1 7 1 2dbe13dcd4d3e5349e6ea010203c4874 | |
| CID0658795 cd41a357317ad2cdfe7c3be281f74ea9 [R]C(=O)N 3 1 0d0b23577e916d801b16c79ee41cc7a9 | |
| CID0658795 b8edb181ba5993d221071ff97cef9af7 [R]c1ccc([R])c([R])c1 6 3 9b507d773616c554f110c2505e8f9a4a | |
| CID0658795 a93d78ee7f73f76b489bd8a77e92c65a [R]C(=C([R])C)[R] 3 3 1e680a0ff1321991fd91e27643a63e94 | |
| CID0658795 59b597bdca2d6ce05597650fffd22a06 [R]\C(=C(\[R])/C(=O)N)\C 6 2 ad4414c1a078abd4479bf507a92c72db | |
| CID0658795 2b9b9124c08296c9fed9ae81e11f0126 [R]N\C(=C(\[R])/C(=O)N)\C 7 2 fa956cf48e421f6d6f327ecee19f7b28 | |
| CID0658795 a3d62a6aba798a60fb58842d10d08bc2 [R]N\C(=C(\C#N)/C(=O)N)\C 9 1 d923c497ad6fa2bfb97bee8785cc2f36 | |
| CID0658795 138607086988192351de9f08309a0dd0 [R]CN\C(=C(\[R])/C(=O)N)\C 8 2 be5f91ea90f5459cc32e7dc5d4b930a1 | |
| CID0658795 8d5d61c7bbbf29d1ca9ee7b7c285c173 [R]\C(=C(\C#N)/C(=O)N)\C 8 1 b1dd3e6cfc911d4d68ae67959c041d2d | |
| CID0658795 52d9dc8b5c127a8c2271a2f616a12945 [R]CNC(=C([R])[R])C 5 3 86d4ff5dc8c4a24fe1c4a656a3e41253 | |
| CID0658795 5d7bd41f3d5e8a78cd85a3e0eb515ce2 [R]CN\C(=C(/[R])\C#N)\C 7 2 c9d941555a21daea99473ca7dbf823a4 | |
| CID0658795 490ab1f0eacd310f54845f7700b58ef3 [R]NC(=C([R])[R])C 4 3 f3720625b84547fa0342130d71c222fa | |
| CID0658795 675b9217654d8f1726c6000e97898db9 [R]N\C(=C(/[R])\C#N)\C 6 2 8424993d41bba2426a96b2cea90fe2cc | |
| CID0658795 cd6742f774bcc36f54b5049f2ab13074 [R]\C(=C(/[R])\C#N)\C 5 2 01e71173afd3a4a95e745605a73dd3c3 | |
| CID0658795 2af9016e0c2c258faf48da5205783cfb [R]c1ccc([R])c(OC)c1 8 2 454bce6e68642781b450a56943ddf3b4 | |
| CID0658795 c282d4b5e744abde59fd562cf8229dda [R]Cc1ccc([R])c(OC)c1 9 2 d556d2e4152732d93bf9ac12147f9706 | |
| CID0658795 898878b148c9c8e80633531f07a3a47f [R]c1ccc(OC)c([R])c1 8 2 454bce6e68642781b450a56943ddf3b4 | |
| CID0658795 e35c1ad1f40a9080e226b3807171c9dc [R]Cc1ccc(OC)c([R])c1 9 2 d556d2e4152732d93bf9ac12147f9706 | |
| CID0658795 6d8716f54d2b13b55fdcc5374a0050dc [R]NCc1ccc([R])c([R])c1 8 3 b0bf920d09f64b72b6706b586504b044 | |
| CID0658795 2ac191a4a0033794abbc677e7ed89dcf [R]Cc1ccc([R])c([R])c1 7 3 e2b60e73b488be63f1b8f776fd054120 | |
| CID0660128 a3a4052f21a7a4058dcdb302e6b9f33e [R]N1C=C([R])C=C(Br)C1=O 8 2 dc51fb3fcd0bd0b2d95dfe4a981fc0e7 | |
| CID0660128 35065791899b93ce68fc2efe276d6bc5 [R]c1ccc2OCOc2c1 9 1 c745e37b63771e4383d17aa77e7022dd | |
| CID0660128 b99f4e0e3deb2a2cc8f77f23f41fa003 [R]C(=O)OC 4 1 29bf41103309565e679bc2ab97128ce3 | |
| CID0660128 2c33d2f7ffc88e627cbb17bafd382a11 [R]CN1C=C([R])C=C(Br)C1=O 9 2 1495331ad0106b916b8b8c0a3788a710 | |
| CID0660128 450d51b4d5e5e12d248540582bd747a2 [R]Cc1ccc2OCOc2c1 10 1 a900d992cb492dfc9dbb61c30176db41 | |
| CID0661045 a3a4052f21a7a4058dcdb302e6b9f33e [R]N1C=C([R])C=C(Br)C1=O 8 2 085320c276a442f1ef9427ea87b6faa3 | |
| CID0661045 b99f4e0e3deb2a2cc8f77f23f41fa003 [R]C(=O)OC 4 1 cb9a1fb61bda597e7139be60c3b18f3b | |
| CID0661045 b8edb181ba5993d221071ff97cef9af7 [R]c1ccc([R])c([R])c1 6 3 4f91a4547dbadfbea7cf4d78cae1b7f4 | |
| CID0661045 2c33d2f7ffc88e627cbb17bafd382a11 [R]CN1C=C([R])C=C(Br)C1=O 9 2 fe0613ccacb17f06765e38e8d608c2df | |
| CID0661045 2af9016e0c2c258faf48da5205783cfb [R]c1ccc([R])c(OC)c1 8 2 fa59b9d59fb82a2e459900ce86c52d24 | |
| CID0661045 de9c513fc202e8f20cbcae1fa2848475 [R]c1ccc(OC)c(OC)c1 10 1 c745e37b63771e4383d17aa77e7022dd | |
| CID0661045 d923c497ad6fa2bfb97bee8785cc2f36 [R]Cc1ccc(OC)c(OC)c1 11 1 a900d992cb492dfc9dbb61c30176db41 | |
| CID0661045 c282d4b5e744abde59fd562cf8229dda [R]Cc1ccc([R])c(OC)c1 9 2 fc4e0abd68602694c8b19ef87dcbd5b4 | |
| CID0661045 898878b148c9c8e80633531f07a3a47f [R]c1ccc(OC)c([R])c1 8 2 fa59b9d59fb82a2e459900ce86c52d24 | |
| CID0661045 e35c1ad1f40a9080e226b3807171c9dc [R]Cc1ccc(OC)c([R])c1 9 2 fc4e0abd68602694c8b19ef87dcbd5b4 | |
| CID0661045 2ac191a4a0033794abbc677e7ed89dcf [R]Cc1ccc([R])c([R])c1 7 3 2e00652eb5da8368e0976d31bcdfa6f5 | |
| CID0661441 c230b0bb3e580833ad3d825b9444a5c6 [R]C(=O)O 3 1 5d2785e533e2b6377010a36f99f51e47 | |
| CID0661441 cf53f11d5494c490e6a688dd860241a4 [R]SC([R])C 3 2 5fa63d8fb698f530e2ea89628ba2c5d6 | |
| CID0661441 09ba8023719be9deab8b4b9aae5ecb5b [R]SC(C)C(=O)O 6 1 6f3def4c2e7fb719304cbe206e52e58d | |
| CID0661441 a669a21ecf9e7b0ab276af5d124f4a0b [R]C(C)C(=O)O 5 1 4ae3a11a86d155839f705a26fffe9279 | |
| CID0793991 982d1ba5cb047d28e66a049dc43d1507 [R]CCC 3 1 c466584cb7d1962aa8c7a0bc12a0025f | |
| CID0796100 2e1a5014d8b0810404cf238f525011d6 [R]c1cccc(F)c1 7 1 c5093c27fd30d4dc0de9acb348a24e05 | |
| CID0796100 4f4f233f007239425e6ea1c2ec2f6d8c [R]n1cccn1 5 1 e044e3a6e910a817a50d0e90c2d1fd48 | |
| CID0796100 d59f0ac5ac83d558f48f25483c1531b1 [R]c1cc([R])ncn1 6 2 64a2b3c4b9e8f319f9d09e9dec19b3bb | |
| CID0796100 e2ee0df7d3bd7764677e5b818755dfbc [R]Nc1cccc(F)c1 8 1 26d79097b5f6d4bdd0c848c774aebb87 | |
| CID0796100 508d5d6331c53c7edff2d69c02f2ed50 [R]Nc1cc([R])ncn1 7 2 1beeb2ce47a17ec324ba579a923d924e | |
| CID0979869 3a01fbaa2c834734cf77e5a8568eee41 [R]c1oc(Br)cc1 6 1 1b05049a0af94bed6451626462b3846d | |
| CID0979869 4d81ccb632ba681dd6842d1f3ffe0a77 [R]c1cccc(Cl)c1[R] 7 2 472db4d474003dfe2ad03f7292933197 | |
| CID0979869 94ccb5b2d910c40f747b3924f0f20776 [R]NC(=O)[R] 3 2 0e66147fe6135c520f79772a1b7ab340 | |
| CID0979869 e1c407781f09f5685045d2098372f629 [R]N1CCN([R])CC1 6 2 881f05a5341d275e18645b44c4a7cc4d | |
| CID0979869 b63e309b66092bec1ae7cd60ecefaa39 [R]NC(=O)c1oc(Br)cc1 9 1 86a238bc5d11f0aca92033eab613fcc7 | |
| CID0979869 eba6fac994bdec9ba0a7dceb7d75059d [R]C(=O)Nc1cccc(Cl)c1[R] 10 2 e49d9343ccb5c43319f1d3970d0259ab | |
| CID0979869 4280ce38dd08ade4082c8a6e678006eb [R]N1CCN(CC)CC1 8 1 28950805ac3a423e63b348603758b7d7 | |
| CID1045996 c3d90dee44e7363b54950ba04d2445dc [R]c1oc2ccccc2c1[R] 9 2 47d1b4f2867045abbcf9f0826874da5a | |
| CID1045996 94ccb5b2d910c40f747b3924f0f20776 [R]NC(=O)[R] 3 2 f52ff82a7a89aab385c2061baf899b90 | |
| CID1045996 cd41a357317ad2cdfe7c3be281f74ea9 [R]C(=O)N 3 1 c5cbdff73b3f20f45ecd43cea6127e89 | |
| CID1045996 b8edb181ba5993d221071ff97cef9af7 [R]c1ccc([R])c([R])c1 6 3 926a18ef866414ed99d058f0cbde6c5a | |
| CID1045996 e70f6cf23e5b4a1d4c852d424dabd6ff [R]OCC 3 1 c484d360090089d038f7b7f79e334a24 | |
| CID1045996 e70f6cf23e5b4a1d4c852d424dabd6ff [R]OCC 3 1 be081c7aa49f7c26f9c02c86f2f99d04 | |
| CID1045996 1c8f1342fd4b742c3c074bcc9632d320 [R]CC(=O)N[R] 4 2 3c4078ce6ede6d21b282d9be404cff4c | |
| CID1045996 e6dd1f3cb235024deb09e8adea218003 [R]C(=O)Nc1c([R])oc2ccccc12 12 2 ddb200a9a266daf4264a2199b10d42fc | |
| CID1045996 69f9cdfa7b1b73c8f34681f779d73a10 [R]c1c(oc2ccccc12)C(=O)N 12 1 6abc7523ad8d8d0c9fe28b88781a53b5 | |
| CID1045996 a896f422cdda3cad1f2f214e1ead3255 [R]Oc1cc([R])ccc1[R] 7 3 4511764461ceb95a49e83aa1670f7e0f | |
| CID1045996 03db71ca1ace27a3cfe81ab99db0eb79 [R]Oc1ccc([R])cc1O[R] 8 3 b30b1924158c95ae8179bec55fe72a73 | |
| CID1045996 7f58abb2f25dff6237392f190be54833 [R]Cc1ccc(O[R])c(O[R])c1 9 3 e39ee03ebdf9f9915f92b55472f65f0a | |
| CID1045996 c7f9092954ac9772b82b8cb76aeb8e40 [R]NC(=O)Cc1ccc(O[R])c(O[R])c1 12 3 653648e84c9bd139617f58d590c829ee | |
| CID1045996 48aeda531b489db27b3c725170f0b644 [R]Cc1ccc(O[R])c(OCC)c1 11 2 bcba2f1507d6ef5e44a926fb9fd9ea60 | |
| CID1045996 e5473d277007004721e62ee5e4d6feb7 [R]Cc1ccc(OCC)c(O[R])c1 11 2 bcba2f1507d6ef5e44a926fb9fd9ea60 | |
| CID1045996 6c12340861ea1581d2bf283f173bb059 [R]Oc1ccc([R])cc1OCC 10 2 1722037da1efd6139f9d60d51ffbc1f6 | |
| CID1045996 295165e2f42bd48faecc8c662da13484 [R]c1ccc(OCC)c(OCC)c1 12 1 ecd21fe637b612a0fcbe47c288229ef8 | |
| CID1045996 590d4ff85a1696aaaa27da2011b03407 [R]Oc1cc([R])ccc1OCC 10 2 1722037da1efd6139f9d60d51ffbc1f6 | |
| CID1045996 0f1bd95eeef93ecb43f5d6540935b90e [R]Cc1ccc([R])c(O[R])c1 8 3 3d24386fac032a7e481e5a26f3334d6a | |
| CID1045996 2645596311426e7a9de50d78e454e642 [R]NC(=O)Cc1ccc([R])c(O[R])c1 11 3 f2554a4684d873374f0cf3165c6f4190 | |
| CID1045996 2b343ff26a32e3a34876cbb24ae7c864 [R]Cc1ccc([R])c(OCC)c1 10 2 2725d1cb9bfb9cb6a9876588de865bed | |
| CID1045996 7a3888885b840aff9f8c10947c6adfd6 [R]c1ccc([R])c(OCC)c1 9 2 c669bf7684ff5351bc263bde41eb8d26 | |
| CID1045996 d9c569d63443d5dbb9ff9fbf46b96cbc [R]Oc1ccc([R])cc1[R] 7 3 4511764461ceb95a49e83aa1670f7e0f | |
| CID1045996 f531e57f70bd69248a78b1766414b0ce [R]Cc1ccc(O[R])c([R])c1 8 3 3d24386fac032a7e481e5a26f3334d6a | |
| CID1045996 9d398a52f8d9e86a6598aea688c5a441 [R]NC(=O)Cc1ccc(O[R])c([R])c1 11 3 f2554a4684d873374f0cf3165c6f4190 | |
| CID1045996 64a5a985dac573b8bcfd2020d0c46a7a [R]Cc1ccc(OCC)c([R])c1 10 2 2725d1cb9bfb9cb6a9876588de865bed | |
| CID1045996 c4520a611ae4f444a0bc19e4e1a78089 [R]c1ccc(OCC)c([R])c1 9 2 c669bf7684ff5351bc263bde41eb8d26 | |
| CID1045996 1114f1502c1c5f37b43cd2edd1160ff8 [R]NC(=O)Cc1ccc([R])c([R])c1 10 3 1b9efbc665fee09813cafea5497a3776 | |
| CID1045996 2ac191a4a0033794abbc677e7ed89dcf [R]Cc1ccc([R])c([R])c1 7 3 c4a97fd592ffcaaff98961a158360e16 | |
| CID1087003 40ff37b23ab7e50f673813778a2799c9 [R]c1ccccc1 6 1 6dd8dd8ae8c725e76d99dd739cf4ba97 | |
| CID1245872 4a0dd495933856eef7724b025449c0b3 [R]c1cc([R])c([R])s1 5 3 5525137226494742762d28ab017f52ee | |
| CID1245872 aa57f10d408973d56fd07c6f8592e918 [R]c1occc1 5 1 abd0ef21f1502cde1b9475d50824081a | |
| CID1245872 cd41a357317ad2cdfe7c3be281f74ea9 [R]C(=O)N 3 1 1b613539c18fade65a00476d2414d5eb | |
| CID1245872 94ccb5b2d910c40f747b3924f0f20776 [R]NC(=O)[R] 3 2 c2a920f3dee5146fa58d54499e87116d | |
| CID1245872 40ff37b23ab7e50f673813778a2799c9 [R]c1ccccc1 6 1 adec4ec515d21ed18e5e0f7408aa6675 | |
| CID1245872 8ad561bface07875535759b9ce1faebe [R]c1cc(C(=O)N)c([R])s1 8 2 97f597d2cfdff4521b9f82ba8a720f61 | |
| CID1245872 10e91cd35458d498255db33e0ae9d1b4 [R]C(=O)Nc1sc([R])cc1C(=O)N 11 2 08cc6bc46ad7149877169183a5ae3093 | |
| CID1245872 eff25640dafc98102e26fe301ea44dac [R]Cc1cc(C(=O)N)c([R])s1 9 2 5cbbad836921e11908365fbfe4a263d2 | |
| CID1245872 2b6ea346a9850e5115bd414865710f77 [R]C(=O)Nc1sc([R])cc1[R] 8 3 62022f10c3ed221686058bc72717a557 | |
| CID1245872 5a8873c73cc130ce65587050f2d5e022 [R]Cc1cc([R])c(NC(=O)[R])s1 9 3 b564492a945fc495c5c6606b91d3c4b8 | |
| CID1245872 3bb5381058460149342d37d452691600 [R]Cc1cc([R])c([R])s1 6 3 12d87308685e6917802c7736bed446e1 | |
| CID1245872 4e4351044fd9ba010bb3092ab9ede259 [R]NC(=O)c1occc1 8 1 f288d59990314dcbf9fd03e62d2799f9 | |
| CID1245872 644740ac60048143ee0e86d26953489e [R]Cc1ccccc1 7 1 f7e08cb1703912fbea89f31d22b35519 | |
| CID1288597 d7409f5391b48331565ab0de1680103d [R]c1csc(C)n1 6 1 9f451a00815f6c8519245b8462fd15f0 | |
| CID1288597 24997595c9966aba5bd8f55eacd8a841 [R]N1C(=Nc2[nH]ncc2C1=O)[R] 10 2 a3dec046b2bc9b2f60f8fe104000f1f1 | |
| CID1288597 40ff37b23ab7e50f673813778a2799c9 [R]c1ccccc1 6 1 673ddb1b5e5924d37f83122d99d4ee10 | |
| CID1288597 bd199dcf2771cea466e2d205c34476b5 [R]SC1=Nc2[nH]ncc2C(=O)N1[R] 11 2 177ec15504e4151dca9c74637e61038b | |
| CID1288597 b64de3e64d0f0d9fc6848d3b973eef80 [R]SCc1csc(C)n1 8 1 809c7de92ca8ba996dd2f0106938b79f | |
| CID1288597 62d788ecc76e4888e42f89be691f887f [R]Cc1csc(C)n1 7 1 5cde86cc4a2f39e9d840725a21384db2 | |
| CID1294440 3a01fbaa2c834734cf77e5a8568eee41 [R]c1oc(Br)cc1 6 1 5d799ff2d6e1959f59215140fb8683b0 | |
| CID1294440 64c71197c21e5522df9060fd9374e83b [R]N1CCOCC1 6 1 f012ff4eb3f3df27ceafaf5167f9a133 | |
| CID1294440 94ccb5b2d910c40f747b3924f0f20776 [R]NC(=O)[R] 3 2 b8c1a7539465c1afaa0a7988065b15ba | |
| CID1294440 6da339ab75c3d1d1427cad3f0e50c2ef [R]c1ccccc1[R] 6 2 5e164fb4601bbc59d4157fdff8ee2657 | |
| CID1294440 b63e309b66092bec1ae7cd60ecefaa39 [R]NC(=O)c1oc(Br)cc1 9 1 b0716130ae0513ec6b6cc2e58996b470 | |
| CID1294440 3c0fc5320fc164c8a112828272f6789f [R]C(=O)Nc1ccccc1[R] 9 2 d5a8d93a39fb0eb8f82b4df18339ed6f | |
| CID2091134 3ca7fd3b49373186f87380d3dc0c9cd0 [R]c1ccsc1[R] 5 2 ed057bd5cf9c4ee5493db2b9b708f0b4 | |
| CID2091134 94ccb5b2d910c40f747b3924f0f20776 [R]NC(=O)[R] 3 2 d40017be5063e4de3f303650901dead1 | |
| CID2091134 cd41a357317ad2cdfe7c3be281f74ea9 [R]C(=O)N 3 1 3fe1f30fc7773d42ff66de65fb3d324a | |
| CID2091134 777775604b353e82c360d5173799e85d [R]c1cc([R])c([R])c([R])c1 6 4 973a4fa1c787e66930b0ee0fa793efc6 | |
| CID2091134 1c8f1342fd4b742c3c074bcc9632d320 [R]CC(=O)N[R] 4 2 c8d00b6fd9fa52125461169720430890 | |
| CID2091134 8d95afec2a293f6a875cc644d8e1a45d [R]C(=O)Nc1sccc1[R] 8 2 c630820e27e94bef311a9f62fabe2169 | |
| CID2091134 73fc69a0eb6e5c111e6b1fd4ec0aab81 [R]C(=O)Nc1sccc1C(=O)N 11 1 60b2d40f8751497ba5d2f8417841738a | |
| CID2091134 ed35caa2453f752019f6e002a01394a8 [R]CC(=O)Nc1sccc1[R] 9 2 d222f4df33ec9f609311330ca04dd55d | |
| CID2091134 8578d8772ab6c795a10660e14ae3c16e [R]c1sccc1C(=O)N 8 1 816154b706310b4cc02165bda5b80086 | |
| CID2091134 5e42d837111a8d68715c391462e82854 [R]c1cc([R])c([R])c(OC)c1 8 3 932c100791f22e0243672834390c98d8 | |
| CID2091134 02267be7570384ca37c79cabce3f79fc [R]c1cc(OC)c([R])c(OC)c1 10 2 b540731ec9f2e8b4d40524a13789b897 | |
| CID2091134 820ce97b48fb8c34764fdc25c7355c65 [R]Cc1cc(OC)c([R])c(OC)c1 11 2 73dd4f953cfb3981a86368f3d96b0795 | |
| CID2091134 0af2dd65fb3161488f766e864d0e8248 [R]c1cc([R])c(OC)c(OC)c1 10 2 b540731ec9f2e8b4d40524a13789b897 | |
| CID2091134 15e1b9c97aa0978906e0b4a20be91ab2 [R]Cc1cc([R])c(OC)c(OC)c1 11 2 73dd4f953cfb3981a86368f3d96b0795 | |
| CID2091134 7615e9d1cf51481b809a334696bdac1f [R]Cc1cc([R])c([R])c(OC)c1 9 3 40c005ab577b87060fac5b729b64e217 | |
| CID2091134 5e42d837111a8d68715c391462e82854 [R]c1cc([R])c([R])c(OC)c1 8 3 932c100791f22e0243672834390c98d8 | |
| CID2091134 0af2dd65fb3161488f766e864d0e8248 [R]c1cc([R])c(OC)c(OC)c1 10 2 b540731ec9f2e8b4d40524a13789b897 | |
| CID2091134 15e1b9c97aa0978906e0b4a20be91ab2 [R]Cc1cc([R])c(OC)c(OC)c1 11 2 73dd4f953cfb3981a86368f3d96b0795 | |
| CID2091134 7615e9d1cf51481b809a334696bdac1f [R]Cc1cc([R])c([R])c(OC)c1 9 3 40c005ab577b87060fac5b729b64e217 | |
| CID2091134 c3b61895b9c40c70295521ee1efd7073 [R]c1cc([R])c(OC)c([R])c1 8 3 932c100791f22e0243672834390c98d8 | |
| CID2091134 07b54b285c0a3a2bedc32ffb85a13e17 [R]Cc1cc([R])c(OC)c([R])c1 9 3 40c005ab577b87060fac5b729b64e217 | |
| CID2091134 6cf2fbdf8be2be95dfa668d71b2e1aef [R]NC(=O)Cc1cc([R])c([R])c([R])c1 10 4 514524e0cebc285b554ded4ad81b760d | |
| CID2091134 d7bde0391745eef431de8cc1a9bc4a30 [R]Cc1cc([R])c([R])c([R])c1 7 4 5e01600e277117dbfcb0d6315f10a219 | |
| CID2099071 5bbb8410ab155c56222153df89c4109f [R]N([R])S(=O)(=O)[R] 4 3 f606f5bdd28980d7675181c1c9164906 | |
| CID2099071 2563b58ed23b5c3b1527083bc2ee56e6 [R]OC(=O)[R] 3 2 6e2368f9c05edc9a744b3adafa3be9c4 | |
| CID2099071 4a9b05abb892fed9970df98452385179 [R]c1ccc2nc([R])[nH]c2c1 9 2 1be00707ad02187f835cde4ff502a668 | |
| CID2099071 88e8d646a409a3a47522d520919494fb [R]c1n[nH]c2ccccc12 9 1 6f0a67de32b75550c73567c41c6bbb23 | |
| CID2099071 11fb59c537194ddabf77cfb14dc0c98f [R]N(CC)S(=O)(=O)[R] 6 2 e883360b113b85cb5647054e23a1e52c | |
| CID2099071 efe652350abaa773ec07d9574d9559c2 [R]S(=O)(=O)N(CC)CC 8 1 6747f92232956ad2fe461a775b4fc2ca | |
| CID2099071 11fb59c537194ddabf77cfb14dc0c98f [R]N(CC)S(=O)(=O)[R] 6 2 e883360b113b85cb5647054e23a1e52c | |
| CID2099071 74898da880c05406046db37731d6260c [R]COC(=O)[R] 4 2 1b4876f0591fb7eda76de20cf4f50eec | |
| CID2099071 539e1d0db4d63da7c83de72682e07244 [R]OC(=O)c1n[nH]c2ccccc12 12 1 f0c131878c56e49ec4510773d3032a13 | |
| CID2099071 388df9a35ed3dd2feb3180d4f2dcf076 [R]Cc1nc2ccc([R])cc2[nH]1 10 2 0b7d0d4d051502db0bde38c84926e13d | |
| CID2377706 ae7cd6dfac77300c9a7c2a9e31b6c9ed [R]S(=O)(=O)[R] 3 2 d347f53b907d6cf19cb8971c2993d2ca | |
| CID2377706 2563b58ed23b5c3b1527083bc2ee56e6 [R]OC(=O)[R] 3 2 37c2fc6633717bc12cec74558e447e74 | |
| CID2377706 94ccb5b2d910c40f747b3924f0f20776 [R]NC(=O)[R] 3 2 4aa78f272074bafbdf112aa83e83dfdc | |
| CID2377706 9d20868abe811ed72b8907c6e6814226 [R]N1CCCC1 5 1 211a361440eaca0157411e2e38e9426e | |
| CID2377706 88e8d646a409a3a47522d520919494fb [R]c1n[nH]c2ccccc12 9 1 211e2ebb40da88d5f4c4168d22287714 | |
| CID2377706 4164124d4a967557812e06a753509776 [R]c1ccc([R])cc1 6 2 aae2328092dded52d46304700e5e0c09 | |
| CID2377706 74898da880c05406046db37731d6260c [R]COC(=O)[R] 4 2 92e524a49df5729b634e9aa1d3ee652e | |
| CID2377706 1615648c547b212aed37ac41eb8677c9 [R]NC(=O)COC(=O)[R] 7 2 bb86c5000ce56fa174bf742efb73573c | |
| CID2377706 1c8f1342fd4b742c3c074bcc9632d320 [R]CC(=O)N[R] 4 2 1fadfd988d7ede855fb7a1aad4c70863 | |
| CID2377706 cbfde57cbacd5c5f82482a0c2c0afbeb [R]S(=O)(=O)N1CCCC1 8 1 ebf7a808f5451b493f0b895a3256fc28 | |
| CID2377706 661e15be7c43b7d726940fd8acd214fc [R]c1ccc(cc1)S(=O)(=O)[R] 9 2 a7ab92e1c9912d0907717af315ab897d | |
| CID2377706 4d29576ab70721ff9b0c2afd12d45e3c [R]C(=O)Nc1ccc(cc1)S(=O)(=O)[R] 12 2 1287bb8f7948b4802f462aa87973ca60 | |
| CID2377706 539e1d0db4d63da7c83de72682e07244 [R]OC(=O)c1n[nH]c2ccccc12 12 1 18ca93677fa304b2020cce5a1fac2fbb | |
| CID2377706 08db99b5450c03428530da26bc589adf [R]C(=O)Nc1ccc([R])cc1 9 2 97b993193d4ecfdfa50b4138314adb32 | |
| CID2377706 265ee31f3bd71cdfa714c0259b134ce4 [R]CC(=O)Nc1ccc([R])cc1 10 2 8f4a36fece7ff23d258bb7faf344b317 | |
| CID2501747 ae7cd6dfac77300c9a7c2a9e31b6c9ed [R]S(=O)(=O)[R] 3 2 47e1ef6371d1d49e6cefab78d9bb3f21 | |
| CID2501747 3ca7fd3b49373186f87380d3dc0c9cd0 [R]c1ccsc1[R] 5 2 0e6409500ea6d0fe659ed7c9a16e59f9 | |
| CID2501747 94ccb5b2d910c40f747b3924f0f20776 [R]NC(=O)[R] 3 2 9c97628a8dbf37cec2f387d39bed99a6 | |
| CID2501747 cd41a357317ad2cdfe7c3be281f74ea9 [R]C(=O)N 3 1 f058848a3ff47160f714277457e5fd27 | |
| CID2501747 1f2ca5fa50abd32418ce8479ef496a49 [R]N1CCCCC1 6 1 4adf462aad691cab806b4ddc8d9a6e35 | |
| CID2501747 4164124d4a967557812e06a753509776 [R]c1ccc([R])cc1 6 2 edb68a48c2775d99159d276eba32757f | |
| CID2501747 9c114cee4d02f92bcdff3a7836e07dec [R]S(=O)(=O)N1CCCCC1 9 1 24578fa439aa37b95a9076901431ec2f | |
| CID2501747 661e15be7c43b7d726940fd8acd214fc [R]c1ccc(cc1)S(=O)(=O)[R] 9 2 749aaaec664c74104a64c0193312d136 | |
| CID2501747 3b7ea99dc991d61d1dd20299fabf0452 [R]NC(=O)c1ccc(cc1)S(=O)(=O)[R] 12 2 53c20e85b6493e6bbcf0ca3e294bfdc4 | |
| CID2501747 8d95afec2a293f6a875cc644d8e1a45d [R]C(=O)Nc1sccc1[R] 8 2 b9159027b9704eab08a0348f88e807a6 | |
| CID2501747 73fc69a0eb6e5c111e6b1fd4ec0aab81 [R]C(=O)Nc1sccc1C(=O)N 11 1 eaf0808b68839b1ff050ed99b105d44a | |
| CID2501747 8578d8772ab6c795a10660e14ae3c16e [R]c1sccc1C(=O)N 8 1 31d023d483e816fa29ec7cede74a4707 | |
| CID2501747 3b7bea15e513aba897198f52a17edff6 [R]NC(=O)c1ccc([R])cc1 9 2 402513aae80e67749bd76c9412133b3a | |
| CID2575371 3ca7fd3b49373186f87380d3dc0c9cd0 [R]c1ccsc1[R] 5 2 9409b5971383ac876b653c3da553d570 | |
| CID2575371 1900051bb5332de8822612ea9f672e97 [R]N1C(=Nc2ccccc2C1=O)[R] 11 2 de1f3a71c89ed51f9b93f422fd71f3e7 | |
| CID2575371 c31f7927e1ad6441d53e8c50bbfc6725 [R]CCCO 4 1 eb12228da8bddecb394fa3cb6fb72d68 | |
| CID2575371 94ccb5b2d910c40f747b3924f0f20776 [R]NC(=O)[R] 3 2 ad47483aa34623b6168b28eea2ec444b | |
| CID2575371 cd41a357317ad2cdfe7c3be281f74ea9 [R]C(=O)N 3 1 685db0c50d47295021203e208c8d2543 | |
| CID2575371 adf2bc81282794ccff733cae00b8f17d [R]NC(=O)CS[R] 5 2 510154ba2fb13119f02c3653c02f6034 | |
| CID2575371 1c8f1342fd4b742c3c074bcc9632d320 [R]CC(=O)N[R] 4 2 3bdbe20ac94187afc558058845c11d00 | |
| CID2575371 960a0f88a271a8a2e76844bb674b322b [R]SC1=Nc2ccccc2C(=O)N1[R] 12 2 aef6602b84152742a2f2d4cebf4ddf6d | |
| CID2575371 d1869c0b0410570a2d1525cce3478e82 [R]SCC(=O)Nc1sccc1[R] 10 2 6088d6483e0a933a6dcf9b5b088ae92e | |
| CID2575371 8d95afec2a293f6a875cc644d8e1a45d [R]C(=O)Nc1sccc1[R] 8 2 bfa59561f00a6e2507ad4534ca4e950f | |
| CID2575371 73fc69a0eb6e5c111e6b1fd4ec0aab81 [R]C(=O)Nc1sccc1C(=O)N 11 1 49d38401ec140ce2438b2a09121abf5d | |
| CID2575371 438a7db88045fbe38da9000d1efa08c9 [R]CC(=O)Nc1sccc1C(=O)N 12 1 09747049e11aa7f8cfed3394fc52c24e | |
| CID2575371 ed35caa2453f752019f6e002a01394a8 [R]CC(=O)Nc1sccc1[R] 9 2 5433a46fe338c532c200bea5a5e6f407 | |
| CID2575371 8578d8772ab6c795a10660e14ae3c16e [R]c1sccc1C(=O)N 8 1 de86e30032cae7cf41a47e8337834187 | |
| CID2589475 9ad05de67e509ed28043152f0b67dd95 [R]N1C(=Nc2sc(C)c(C)c2C1=O)[R] 12 2 d674681987ea5fe9ba2c3cb7ce96c855 | |
| CID2589475 3ca7fd3b49373186f87380d3dc0c9cd0 [R]c1ccsc1[R] 5 2 0876ecf5f54c69d4d191f90e28fd87fc | |
| CID2589475 94ccb5b2d910c40f747b3924f0f20776 [R]NC(=O)[R] 3 2 f5f20f0dc499782e5e4fca200e47cfbc | |
| CID2589475 cd41a357317ad2cdfe7c3be281f74ea9 [R]C(=O)N 3 1 69d21fcba06da63956fa968cbab1db99 | |
| CID2589475 adf2bc81282794ccff733cae00b8f17d [R]NC(=O)CS[R] 5 2 e041e2f1428a93d6a70b187434e414b9 | |
| CID2589475 1c8f1342fd4b742c3c074bcc9632d320 [R]CC(=O)N[R] 4 2 0e9671988b1b3f51c8c8bd27fc6af99a | |
| CID2589475 1deb7cd7f65a68f03cbd1660b3fe65c0 [R]CC=C 3 1 2e7894dc171f97fd06ba80b5121434a7 | |
| CID2589475 d1869c0b0410570a2d1525cce3478e82 [R]SCC(=O)Nc1sccc1[R] 10 2 0eec0812a6962840801840ca00defe06 | |
| CID2589475 8d95afec2a293f6a875cc644d8e1a45d [R]C(=O)Nc1sccc1[R] 8 2 a8666cc7e7734e557fabfb34bc020527 | |
| CID2589475 73fc69a0eb6e5c111e6b1fd4ec0aab81 [R]C(=O)Nc1sccc1C(=O)N 11 1 3db3040a159edf77f32a61f6ed6f14df | |
| CID2589475 438a7db88045fbe38da9000d1efa08c9 [R]CC(=O)Nc1sccc1C(=O)N 12 1 0145f4911c92e87ce5dd4a30b4f7f72c | |
| CID2589475 ed35caa2453f752019f6e002a01394a8 [R]CC(=O)Nc1sccc1[R] 9 2 b1726885c51f57408935307cb8cb44b6 | |
| CID2589475 8578d8772ab6c795a10660e14ae3c16e [R]c1sccc1C(=O)N 8 1 c855bb826d204847c752884745d26dcf | |
| CID2953401 ec7d694c9f59163e38083a3c5accd851 [R]N1C(=S)Nc2ccccc2C1=O 12 1 1cb9569d089b36fda12f3b2d736aecbb | |
| CID2953401 94ccb5b2d910c40f747b3924f0f20776 [R]NC(=O)[R] 3 2 d6dc59b49c9d992c5d9669f9e8e095a4 | |
| CID2953401 7acbe9d24d1580f5db2a2cfbf8d22b0e [R]C1CCC([R])CC1 6 2 f9aa6211f9b4ab9a3f77b986c5f74722 | |
| CID2953401 d8aa80cc7cf96e274c68c5cca70dbeb5 [R]CCNC(=O)[R] 5 2 742a8c83751f429a7d747133dbca3862 | |
| CID2953401 5bde16c7f6e79d6e5df1e43541df0c99 [R]C(=O)NCCOC 7 1 b4c89580692819e2aaa65ed2979c8c35 | |
| CID2953401 0e82ca938f8827db4f845afe45972967 [R]CCOC 4 1 4619ae74f7b759b749fb44dd02c70af3 | |
| CID2953401 129ff0b95cd03c4d40cb217ad8fd373b [R]NC(=O)C1CCC([R])CC1 9 2 4de0018e9b8324bfafb9d9c144187c1a | |
| CID2953401 f42882de9be90903adf8e8bce57e5f79 [R]CC1CCC(CC1)C(=O)N[R] 10 2 a67c5c45f09f985f5555f60457aadd85 | |
| CID2953401 2decf05f43a4613538a2f7bd4863c128 [R]CCNC(=O)C1CCC(C[R])CC1 12 2 3d41a061f2f6448017cc067317d10e63 | |
| CID2953401 a426f5c275feeb0454f6c6c68b635100 [R]CCNC(=O)C1CCC([R])CC1 11 2 359ed4c0f6260ea2b3f74f7cb3cfaa1d | |
| CID2953401 ad93b521cacb9f4cc7988a6ae5e37ca8 [R]CC1CCC([R])CC1 7 2 0fe2e955e1c2c4d8d5f507a501fc0159 | |
| CID2962251 04a463fee819cb4b30360dbc1a11cb55 [R]c1cccc(Br)c1 7 1 5968b0c41227322ae81a3648f13b5760 | |
| CID2962251 8fcbeb6fa1f9477222260e55d8842991 [R]C1CC(=NO1)[R] 5 2 29c3e4be5c3f0843ed90cec5cda75b4e | |
| CID2962251 94ccb5b2d910c40f747b3924f0f20776 [R]NC(=O)[R] 3 2 e21e98d81c88300b5bddaf11b1fa67e9 | |
| CID2962251 482c9ba5371cb2445128177a3c9a265a [R]c1cnn([R])c1 5 2 f93ed475b6e90f7f66e947f10a3b65dc | |
| CID2962251 982d1ba5cb047d28e66a049dc43d1507 [R]CCC 3 1 9e87f2994d7d0441622eadcae32d21f0 | |
| CID2962251 1e2396bdd17c15f3e40fe55ca74afde9 [R]NC(=O)C1CC(=NO1)[R] 8 2 c9a2693c7aaee66e80b271e801796def | |
| CID2962251 d66a967f6506f0b7b9cc2591af6cc9ba [R]C(=O)Nc1cnn([R])c1 8 2 f6cff4405f3c52454579368239383ea2 | |
| CID2962251 f18246b3b8842d47942fd00aba7ad983 [R]C(=O)Nc1cnn(CCC)c1 11 1 9c8a0d93d8b4ebda67f98311eeb73c21 | |
| CID2962251 5b9193fb09b32d54974876116cde7239 [R]c1cnn(CCC)c1 8 1 0050e49484a41d567ab4771486edca3b | |
| CID2971411 3ca7fd3b49373186f87380d3dc0c9cd0 [R]c1ccsc1[R] 5 2 818442322b22bc8b64d685bc6a540ef1 | |
| CID2971411 f4fca06b529baa0a36072ec06e4af440 [R]c1cccs1 5 1 73fc69a0eb6e5c111e6b1fd4ec0aab81 | |
| CID2971411 94ccb5b2d910c40f747b3924f0f20776 [R]NC(=O)[R] 3 2 8aa5c5326a644e2127ea68d2e1c5b2de | |
| CID2971411 cd41a357317ad2cdfe7c3be281f74ea9 [R]C(=O)N 3 1 c62a239754f29bb6d43f052325c19f59 | |
| CID2972189 5cd96f7c4836124704977b8899b94423 [R]C1NC(=O)NC1C 7 1 2d9d7a00d3ea96d369b3104a465a054a | |
| CID2972189 94ccb5b2d910c40f747b3924f0f20776 [R]NC(=O)[R] 3 2 f202eed7a35efa6df47e488dfb28905a | |
| CID2972189 d41ce11b8db19ef58f31561bb166a5cb [R]CCCCC[R] 5 2 e2d7f525f426298f7e9de9e7f6bc7710 | |
| CID2972189 1182f5a434f5ca9647925fe1b4fefb96 [R]c1ccc(C)cc1 7 1 d1c00dd9b6dce99667be549f141c5bc0 | |
| CID2972189 2f7f05caef4578684c7c682fa5c1ff35 [R]CCCCCC(=O)N[R] 8 2 b18057b3cea9b76fb3c6f639da427b0d | |
| CID2972189 7979026c220d5ac31d117ef756f0c3fe [R]C(=O)Nc1ccc(C)cc1 10 1 8b2f18879f679d3743824ece90a2d174 | |
| CID2974150 5cd96f7c4836124704977b8899b94423 [R]C1NC(=O)NC1C 7 1 1c2c48a7e90ab7cfa055739beb02f526 | |
| CID2974150 94ccb5b2d910c40f747b3924f0f20776 [R]NC(=O)[R] 3 2 268704d0439ae9b3b06be7d7922d8bd0 | |
| CID2974150 d41ce11b8db19ef58f31561bb166a5cb [R]CCCCC[R] 5 2 2c76a172260d87b9c472b0fedcc867c2 | |
| CID2974150 40ff37b23ab7e50f673813778a2799c9 [R]c1ccccc1 6 1 5bd9b1bd8a4a3be94042aeb69371bc93 | |
| CID2974150 2f7f05caef4578684c7c682fa5c1ff35 [R]CCCCCC(=O)N[R] 8 2 718307a75a311d122049772e0a9761f4 | |
| CID2974150 b1fb519841649a5d2883632f6d57c26c [R]CCCCCC(=O)NCC[R] 10 2 741ae71be965c22205c8ea67d103505d | |
| CID2974150 d8aa80cc7cf96e274c68c5cca70dbeb5 [R]CCNC(=O)[R] 5 2 6d45469b4669e11d960115ca6e61382b | |
| CID2974150 afb6a80a7dc12e95d8793bfc5b3720bc [R]C(=O)NCCc1ccccc1 11 1 8b2f18879f679d3743824ece90a2d174 | |
| CID2974150 dba34ca5632e2e1723656cb6009fdafa [R]CCc1ccccc1 8 1 d1c00dd9b6dce99667be549f141c5bc0 | |
| CID3236317 bbe7b0918349051b84a2ac651db7068f [R]c1ccc(F)cc1 7 1 c03879b70eefee57f4d717fff828497f | |
| CID3236317 8fcbeb6fa1f9477222260e55d8842991 [R]C1CC(=NO1)[R] 5 2 b73ba3e6ee37d3b8b313a9b1f427cd9c | |
| CID3236317 94ccb5b2d910c40f747b3924f0f20776 [R]NC(=O)[R] 3 2 1dc6e7a9148b03c5c6b8ef5d15cedf62 | |
| CID3236317 259d5c4b05e0489434d305083df59972 [R]C(=O)C 3 1 f582c37f0e9ca3752d4a616aa7bdc300 | |
| CID3236317 4164124d4a967557812e06a753509776 [R]c1ccc([R])cc1 6 2 e04ab9b214f81ffa4c2c7b036f205c22 | |
| CID3236317 1e2396bdd17c15f3e40fe55ca74afde9 [R]NC(=O)C1CC(=NO1)[R] 8 2 abd43aea30562dcda1f6bff76e072f4d | |
| CID3236317 08db99b5450c03428530da26bc589adf [R]C(=O)Nc1ccc([R])cc1 9 2 605d52b7002788f97a794fd890ba60e0 | |
| CID3236317 5c090fd71abb3a3cf1f31256527edf01 [R]c1ccc(cc1)C(=O)C 9 1 aa205a7c420e4fbf10c2a7783977f50f | |
| CID3236465 cd41a357317ad2cdfe7c3be281f74ea9 [R]C(=O)N 3 1 7f982ad6a43fe314997cfcb9a2e77448 | |
| CID3236465 777775604b353e82c360d5173799e85d [R]c1cc([R])c([R])c([R])c1 6 4 53a4bf5d568a97d038a4caf7c4f35224 | |
| CID3236465 a93d78ee7f73f76b489bd8a77e92c65a [R]C(=C([R])C)[R] 3 3 cd45c53f8ca1ec2036411be1e00f393c | |
| CID3236465 1e66aa1ced35748ad2e6f9aa640a3646 [R]\C(=C(/[R])\C(=O)N)\C 6 2 6b6541dd3881327f7d42052372238cec | |
| CID3236465 bc3c7fd636ada507c6175c899d56b67c [R]N\C(=C(/[R])\C(=O)N)\C 7 2 9f526c3cb33d1715c4ff001ee0474e04 | |
| CID3236465 bc0fbd3c7c72f4e9c1c1e9dac99184f4 [R]N\C(=C(/C#N)\C(=O)N)\C 9 1 60b2d40f8751497ba5d2f8417841738a | |
| CID3236465 db2ca9e482273e04f76ae620f22405d2 [R]CN\C(=C(/C#N)\C(=O)N)\C 10 1 c76a823c591b9b51389cede68b3da393 | |
| CID3236465 df85ed6ae3ed6bf4ba0087d19fd993ad [R]CN\C(=C(/[R])\C(=O)N)\C 8 2 f3dee2a1dd49f282cb85eafc99855b6b | |
| CID3236465 3818fe5fddb286b6a32f41572322718b [R]\C(=C(/C#N)\C(=O)N)\C 8 1 ddde94b9980215ea190e9958a8f02097 | |
| CID3236465 52d9dc8b5c127a8c2271a2f616a12945 [R]CNC(=C([R])[R])C 5 3 72969129b8165abaf5b97e037e0b0cb1 | |
| CID3236465 c984252354aefa2e5d364f055eedc0a8 [R]CN\C(=C(\[R])/C#N)\C 7 2 d222f4df33ec9f609311330ca04dd55d | |
| CID3236465 490ab1f0eacd310f54845f7700b58ef3 [R]NC(=C([R])[R])C 4 3 0f36f83113bbfe9ab73c65acb1cc2534 | |
| CID3236465 b0561e15bcdc556af7e582ae2c7e20ce [R]N\C(=C(\[R])/C#N)\C 6 2 c630820e27e94bef311a9f62fabe2169 | |
| CID3236465 981c96933a877c640cbb5b59243a9f8d [R]\C(=C(\[R])/C#N)\C 5 2 7e5d4dae1ce12cb2345c70dbadbd6a19 | |
| CID3236465 5e42d837111a8d68715c391462e82854 [R]c1cc([R])c([R])c(OC)c1 8 3 012b45bdc5bc3bb311bb65ece7edeee7 | |
| CID3236465 02267be7570384ca37c79cabce3f79fc [R]c1cc(OC)c([R])c(OC)c1 10 2 533e8fe4a37cf051e79cc3c3edcc310b | |
| CID3236465 0af2dd65fb3161488f766e864d0e8248 [R]c1cc([R])c(OC)c(OC)c1 10 2 533e8fe4a37cf051e79cc3c3edcc310b | |
| CID3236465 7615e9d1cf51481b809a334696bdac1f [R]Cc1cc([R])c([R])c(OC)c1 9 3 6ecd6e048c83580e0f6736ffb4159895 | |
| CID3236465 41ce2e1304ce298325a5daf64a73a1ea [R]NCc1cc([R])c([R])c(OC)c1 10 3 0d367ae1ea9eaeeac4d5874dd5f7e532 | |
| CID3236465 5e42d837111a8d68715c391462e82854 [R]c1cc([R])c([R])c(OC)c1 8 3 08d3dab5ebe1b743f07c3a08568ee5f3 | |
| CID3236465 0af2dd65fb3161488f766e864d0e8248 [R]c1cc([R])c(OC)c(OC)c1 10 2 533e8fe4a37cf051e79cc3c3edcc310b | |
| CID3236465 7615e9d1cf51481b809a334696bdac1f [R]Cc1cc([R])c([R])c(OC)c1 9 3 e8135ba00e7da16f78347f1f5fa50ffd | |
| CID3236465 41ce2e1304ce298325a5daf64a73a1ea [R]NCc1cc([R])c([R])c(OC)c1 10 3 51e77046fc7b8436599bb1dbb3c6562e | |
| CID3236465 c3b61895b9c40c70295521ee1efd7073 [R]c1cc([R])c(OC)c([R])c1 8 3 cc859111a12851fd4b9cd4950becda7c | |
| CID3236465 07b54b285c0a3a2bedc32ffb85a13e17 [R]Cc1cc([R])c(OC)c([R])c1 9 3 f26d539bb1a96bc97983d8b9461a9efc | |
| CID3236465 0eb26e4da08eabdc5334d28b5866663f [R]NCc1cc([R])c(OC)c([R])c1 10 3 0baecca109e6ac9a1e0faba9f61b150c | |
| CID3236465 141845b41c4db2b4784096a3751c6fda [R]NCc1cc([R])c([R])c([R])c1 8 4 4defb6f3e182e7508557e2169c6c78c5 | |
| CID3236465 d7bde0391745eef431de8cc1a9bc4a30 [R]Cc1cc([R])c([R])c([R])c1 7 4 142edf5ff0045ba5144b1b0ed45d709b | |
| CID3238045 8fcbeb6fa1f9477222260e55d8842991 [R]C1CC(=NO1)[R] 5 2 3870725ded662e004600d02920ce4e6c | |
| CID3238045 94ccb5b2d910c40f747b3924f0f20776 [R]NC(=O)[R] 3 2 9c44e5a9fdb3b02a9a7ae4451bf95d7f | |
| CID3238045 b99f4e0e3deb2a2cc8f77f23f41fa003 [R]C(=O)OC 4 1 e39eb92f1fb05397f8475b398b93803e | |
| CID3238045 4916794fa5014840f545e4e6693254e5 [R]c1cnn([R])c1C 6 2 6c5b06fbb25869fa142aa56c567a9d05 | |
| CID3238045 6da339ab75c3d1d1427cad3f0e50c2ef [R]c1ccccc1[R] 6 2 7ddf7b50cc0652280c7a972035a297bf | |
| CID3238045 1e2396bdd17c15f3e40fe55ca74afde9 [R]NC(=O)C1CC(=NO1)[R] 8 2 3184d661bb943702c842207fa74a12a2 | |
| CID3238045 3c394d8c3044c567cb027c6bda2355f2 [R]C1CC(=NO1)c2cnn([R])c2C 11 2 33658707010924498d42bacfec0bcda3 | |
| CID3238045 3c0fc5320fc164c8a112828272f6789f [R]C(=O)Nc1ccccc1[R] 9 2 4521d4223331d0e3b3e88d44f17ab571 | |
| CID3238045 6e79403be5ab3ccde2532ab8e8bf0f12 [R]c1ccccc1C(=O)OC 10 1 6b89ae13deed813d1967aea061d41136 | |
| CID3238045 1d01605f8ed43bf4f46202984bc0d155 [R]c1cnn(CC)c1C 8 1 004d5b56f14cb20799a01662e27ee3e4 | |
| CID3238372 280cad05f0ac04d13bef256ea87219f7 [R]N1C(=O)Nc2ccccc2C1=O 12 1 22fa2b476dac74ab601ae61e6314f8a0 | |
| CID3238372 e1c407781f09f5685045d2098372f629 [R]N1CCN([R])CC1 6 2 af2216d0c59c0559f0fae28bcdad09d2 | |
| CID3238372 40ff37b23ab7e50f673813778a2799c9 [R]c1ccccc1 6 1 742bfbfe86f544e39dfb0facf1e03c79 | |
| CID3238372 4164124d4a967557812e06a753509776 [R]c1ccc([R])cc1 6 2 3ac4ac0967831a690053d1b8a96e9159 | |
| CID3238372 fff923760e9b5128c2bbc84afdecf548 [R]N1CCN(CC1)C(=O)[R] 8 2 71cf0432ac79d594a5820c07d4c889f9 | |
| CID3238372 981a7d6563bcd4050bb4b0cbfcf798ad [R]C(=O)c1ccc([R])cc1 8 2 752318a18c39ef7ee2b11bc50efeff12 | |
| CID3238372 5cae5ceb00eea4a36ce2b0c099cfb817 [R]Cc1ccc(cc1)C(=O)[R] 9 2 100a8ebac62c3c59f7e2161df12265f6 | |
| CID3238372 a2094151dbac92354741f5c9a051b8ec [R]N1CCN(CC1)c2ccccc2 12 1 b3b2ceffecaee5413c169f403c181934 | |
| CID3238372 ea85b643fa324a93ea4e2f512edbd8b3 [R]Cc1ccc([R])cc1 7 2 041860a24a7990aa70541c1047b8647a | |
| CID3239708 8fcbeb6fa1f9477222260e55d8842991 [R]C1CC(=NO1)[R] 5 2 007dd873c3ce282372f4b1dad8be1521 | |
| CID3239708 94ccb5b2d910c40f747b3924f0f20776 [R]NC(=O)[R] 3 2 4a630ad7f1743afede814d7b19904ac2 | |
| CID3239708 9b1014cfd607f7ab417b0c54794c5d47 [R]c1cccc([R])c1[R] 6 3 8d66343ea324e284927131d516ba6d15 | |
| CID3239708 777775604b353e82c360d5173799e85d [R]c1cc([R])c([R])c([R])c1 6 4 d46de2f3ef36bad23f9ec61efa77bc22 | |
| CID3239708 1e2396bdd17c15f3e40fe55ca74afde9 [R]NC(=O)C1CC(=NO1)[R] 8 2 186d62ec2e1cb58439bb713d1eacbbd4 | |
| CID3239708 1f21ae325dc9a19805a04a8365f25af3 [R]C1CC(=NO1)c2cccc([R])c2[R] 11 3 577bc12e50a60afcdfcc9940e5cddc78 | |
| CID3239708 757bcd8509554edc787cc61a8f48f8e2 [R]c1cccc([R])c1OC 8 2 6311f51a0b08df6893c9b66a602d6d03 | |
| CID3239708 6c5b6761b1418b55f23fb63e097e1094 [R]c1cccc(OC)c1OC 10 1 cbfccf26bcfa01a7bbf50fc413b3b3c2 | |
| CID3239708 33688dfa24816ee1fcdc5c587ef6d3dc [R]C(=O)Nc1cc([R])c([R])c([R])c1 9 4 afef47e2838c255fb528f8224c8e4277 | |
| CID3239708 7e324ed6d41b9bfed72f9fd671b149d3 [R]C(=O)Nc1cc([R])c([R])c(OC)c1 11 3 3ff400286acf5675d91f73fb2ba39c6b | |
| CID3239708 7e324ed6d41b9bfed72f9fd671b149d3 [R]C(=O)Nc1cc([R])c([R])c(OC)c1 11 3 3ff400286acf5675d91f73fb2ba39c6b | |
| CID3239708 28ec093bfb4e6f95762af048d84c9dc3 [R]C(=O)Nc1cc([R])c(OC)c([R])c1 11 3 3ff400286acf5675d91f73fb2ba39c6b | |
| CID3239708 f8b56da60e4b054bedbdc980a18a71c6 [R]c1cccc(OC)c1[R] 8 2 6311f51a0b08df6893c9b66a602d6d03 | |
| CID3239708 5e42d837111a8d68715c391462e82854 [R]c1cc([R])c([R])c(OC)c1 8 3 0a0cf87080aa0d5b31c468dff775c8da | |
| CID3239708 02267be7570384ca37c79cabce3f79fc [R]c1cc(OC)c([R])c(OC)c1 10 2 c73db2e39376e52e5e82fc233fb44160 | |
| CID3239708 c76a823c591b9b51389cede68b3da393 [R]c1cc(OC)c(OC)c(OC)c1 12 1 c85923693f831889914046e3151dda6b | |
| CID3239708 0af2dd65fb3161488f766e864d0e8248 [R]c1cc([R])c(OC)c(OC)c1 10 2 c73db2e39376e52e5e82fc233fb44160 | |
| CID3239708 5e42d837111a8d68715c391462e82854 [R]c1cc([R])c([R])c(OC)c1 8 3 0a0cf87080aa0d5b31c468dff775c8da | |
| CID3239708 0af2dd65fb3161488f766e864d0e8248 [R]c1cc([R])c(OC)c(OC)c1 10 2 c73db2e39376e52e5e82fc233fb44160 | |
| CID3239708 c3b61895b9c40c70295521ee1efd7073 [R]c1cc([R])c(OC)c([R])c1 8 3 0a0cf87080aa0d5b31c468dff775c8da | |
| CID3240660 8fcbeb6fa1f9477222260e55d8842991 [R]C1CC(=NO1)[R] 5 2 31de523fe7b6880da688c51ede69a632 | |
| CID3240660 94ccb5b2d910c40f747b3924f0f20776 [R]NC(=O)[R] 3 2 9aa43d8d1f22dddefe9d800daa4a9af8 | |
| CID3240660 b99f4e0e3deb2a2cc8f77f23f41fa003 [R]C(=O)OC 4 1 f4d6889c42f0c843e36db976b4e32227 | |
| CID3240660 7350f21ba65fe40b955794193beb8384 [R]c1cn([R])nc1C 6 2 6c5b06fbb25869fa142aa56c567a9d05 | |
| CID3240660 6da339ab75c3d1d1427cad3f0e50c2ef [R]c1ccccc1[R] 6 2 09a7cff3bf370e22d09674acadc27d5f | |
| CID3240660 1e2396bdd17c15f3e40fe55ca74afde9 [R]NC(=O)C1CC(=NO1)[R] 8 2 d92a2001247749c8385e6396e0a4608e | |
| CID3240660 e284e0eda62c3c5f2c6a757881737622 [R]C1CC(=NO1)c2cn([R])nc2C 11 2 33658707010924498d42bacfec0bcda3 | |
| CID3240660 3c0fc5320fc164c8a112828272f6789f [R]C(=O)Nc1ccccc1[R] 9 2 a4f79afe2284b54d3ed2fb7f8de1ec5e | |
| CID3240660 6e79403be5ab3ccde2532ab8e8bf0f12 [R]c1ccccc1C(=O)OC 10 1 5b7464d89b1b13adb85641fd3b688b52 | |
| CID3240660 81b4b88363f622f3572a37ce0724413d [R]c1cn(CC)nc1C 8 1 004d5b56f14cb20799a01662e27ee3e4 | |
| CID3240978 8fcbeb6fa1f9477222260e55d8842991 [R]C1CC(=NO1)[R] 5 2 363967b01fd94ffd925e42e9ebfdec2b | |
| CID3240978 94ccb5b2d910c40f747b3924f0f20776 [R]NC(=O)[R] 3 2 57ef527e708018b3e5c325756be1b859 | |
| CID3240978 259d5c4b05e0489434d305083df59972 [R]C(=O)C 3 1 3604b8a6ca32c137093c3552bc5a1024 | |
| CID3240978 6e7c97f191099b744eb97abc7f380953 [R]c1cccc([R])c1 6 2 b530cac9e047c57960874be252be297b | |
| CID3240978 4164124d4a967557812e06a753509776 [R]c1ccc([R])cc1 6 2 0fdb6ae9325bfa4d65ac11421904cdbb | |
| CID3240978 1e2396bdd17c15f3e40fe55ca74afde9 [R]NC(=O)C1CC(=NO1)[R] 8 2 53ad373e385df90d4a47d69bf5ab5c84 | |
| CID3240978 7056e805b487e71ef047203a61fd7abe [R]C1CC(=NO1)c2cccc([R])c2 11 2 f1191cdcd3248a83f8c871f61d2fced8 | |
| CID3240978 08db99b5450c03428530da26bc589adf [R]C(=O)Nc1ccc([R])cc1 9 2 a833ec89d3c027d1e6883368405fd1f8 | |
| CID3240978 d282a96cf038b2bba34deee88bb1277f [R]C(=O)Nc1ccc(cc1)C(=O)C 12 1 bf9725730d023a9029f32476b227109a | |
| CID3240978 7dc9c6cb16d0c93c71cc979e0d89a7ae [R]c1cccc(OC)c1 8 1 c03879b70eefee57f4d717fff828497f | |
| CID3240978 5c090fd71abb3a3cf1f31256527edf01 [R]c1ccc(cc1)C(=O)C 9 1 a4e4d90e2237e60c5e2391de8771b8e4 | |
| CID3241191 94ccb5b2d910c40f747b3924f0f20776 [R]NC(=O)[R] 3 2 cc433f065f55ba69e56eda367e5dfe84 | |
| CID3241191 87a640cc527739c842f03cca55c9076f [R]c1cn2ccccc2n1 9 1 561b9a5df8be79864de5faeec6f8fc8f | |
| CID3241191 777775604b353e82c360d5173799e85d [R]c1cc([R])c([R])c([R])c1 6 4 73f5e13bf68659bd4406a85de4eae877 | |
| CID3241191 74493ffd1a692d594d6ba10eec21bf10 [R]CNC(=O)[R] 4 2 bda017ec93e7c9556d38433c94b9ea09 | |
| CID3241191 5e42d837111a8d68715c391462e82854 [R]c1cc([R])c([R])c(OC)c1 8 3 201b7959d808bd02e8d44b0f7154e568 | |
| CID3241191 02267be7570384ca37c79cabce3f79fc [R]c1cc(OC)c([R])c(OC)c1 10 2 2e378386be9cd6dd9d2d78be4f017e88 | |
| CID3241191 c76a823c591b9b51389cede68b3da393 [R]c1cc(OC)c(OC)c(OC)c1 12 1 e260b517fedb06e0547b072244694196 | |
| CID3241191 0af2dd65fb3161488f766e864d0e8248 [R]c1cc([R])c(OC)c(OC)c1 10 2 2e378386be9cd6dd9d2d78be4f017e88 | |
| CID3241191 e23f07565ac61d49ea14fe575d5bcd06 [R]NC(=O)c1cc([R])c([R])c(OC)c1 11 3 74cda18ffa0d3b3911a2a6774d6f34a1 | |
| CID3241191 2255c3a8ac83399457ea760be81b39a8 [R]CNC(=O)c1cc([R])c([R])c(OC)c1 12 3 7c328f8502b41033b4e467e9ce0d98a7 | |
| CID3241191 5e42d837111a8d68715c391462e82854 [R]c1cc([R])c([R])c(OC)c1 8 3 201b7959d808bd02e8d44b0f7154e568 | |
| CID3241191 0af2dd65fb3161488f766e864d0e8248 [R]c1cc([R])c(OC)c(OC)c1 10 2 2e378386be9cd6dd9d2d78be4f017e88 | |
| CID3241191 e23f07565ac61d49ea14fe575d5bcd06 [R]NC(=O)c1cc([R])c([R])c(OC)c1 11 3 74cda18ffa0d3b3911a2a6774d6f34a1 | |
| CID3241191 2255c3a8ac83399457ea760be81b39a8 [R]CNC(=O)c1cc([R])c([R])c(OC)c1 12 3 7c328f8502b41033b4e467e9ce0d98a7 | |
| CID3241191 c3b61895b9c40c70295521ee1efd7073 [R]c1cc([R])c(OC)c([R])c1 8 3 201b7959d808bd02e8d44b0f7154e568 | |
| CID3241191 bfc7b104a12e7395166e6a06187ad5ee [R]NC(=O)c1cc([R])c(OC)c([R])c1 11 3 74cda18ffa0d3b3911a2a6774d6f34a1 | |
| CID3241191 b42142dcf97feaa4eb8059ef3d49cc4c [R]CNC(=O)c1cc([R])c(OC)c([R])c1 12 3 7c328f8502b41033b4e467e9ce0d98a7 | |
| CID3241191 bd4d8e903b2c1fc5352c71d7e393a93d [R]CNC(=O)c1cc([R])c([R])c([R])c1 10 4 25c0bf1c0d1f56fbc934e69c60503875 | |
| CID3241191 9dcff2997593866646749c6010612ccd [R]NC(=O)c1cc([R])c([R])c([R])c1 9 4 a611fe87d7cfd51a15da65f7433f5259 | |
| CID3241191 caca3f65ac9d3c21ad4a3a868959c666 [R]Cc1cn2ccccc2n1 10 1 2ec607314f69a496665fe5b8192daba2 | |
| CID3241493 8fcbeb6fa1f9477222260e55d8842991 [R]C1CC(=NO1)[R] 5 2 429658b4dd4933e6cffa3f6ce437478c | |
| CID3241493 94ccb5b2d910c40f747b3924f0f20776 [R]NC(=O)[R] 3 2 622056e4232e18d064d1e3b56bdfc5bd | |
| CID3241493 6e7c97f191099b744eb97abc7f380953 [R]c1cccc([R])c1 6 2 672e332a130f27c8bbdd41dd5de176b5 | |
| CID3241493 b8edb181ba5993d221071ff97cef9af7 [R]c1ccc([R])c([R])c1 6 3 b69b6116a1d08822cac53c14dbb76331 | |
| CID3241493 1e2396bdd17c15f3e40fe55ca74afde9 [R]NC(=O)C1CC(=NO1)[R] 8 2 22bec7dd4abb97be9785e3ba45c2dacb | |
| CID3241493 7056e805b487e71ef047203a61fd7abe [R]C1CC(=NO1)c2cccc([R])c2 11 2 85a1d63837783f03254d41f7c6b82a05 | |
| CID3241493 c980d2f3faf5e747a5c98ab1a8ce1ff3 [R]C(=O)Nc1ccc([R])c([R])c1 9 3 86832d8f333d09334fb96ab5ba5c9cf0 | |
| CID3241493 af445ba483affc598ba443a48bea6575 [R]C(=O)Nc1ccc([R])c(OC)c1 11 2 3e87e10517de967a54dff344df271e16 | |
| CID3241493 20170f877b39d307761cea3edc7acfc5 [R]C(=O)Nc1ccc(OC)c([R])c1 11 2 3e87e10517de967a54dff344df271e16 | |
| CID3241493 7dc9c6cb16d0c93c71cc979e0d89a7ae [R]c1cccc(OC)c1 8 1 fbbe88226a9d47bc464c58ae6cbc7df5 | |
| CID3241493 2af9016e0c2c258faf48da5205783cfb [R]c1ccc([R])c(OC)c1 8 2 538085ffcfc59d92cf23c2075a19f0bb | |
| CID3241493 de9c513fc202e8f20cbcae1fa2848475 [R]c1ccc(OC)c(OC)c1 10 1 a4e4d90e2237e60c5e2391de8771b8e4 | |
| CID3241493 898878b148c9c8e80633531f07a3a47f [R]c1ccc(OC)c([R])c1 8 2 538085ffcfc59d92cf23c2075a19f0bb | |
| CID3242510 bbe7b0918349051b84a2ac651db7068f [R]c1ccc(F)cc1 7 1 004d5b56f14cb20799a01662e27ee3e4 | |
| CID3242510 8fcbeb6fa1f9477222260e55d8842991 [R]C1CC(=NO1)[R] 5 2 957f5e0bc75e8ea251ca193e4f8e4faf | |
| CID3242510 94ccb5b2d910c40f747b3924f0f20776 [R]NC(=O)[R] 3 2 d65ca6745007b2d94d701d0f8752a639 | |
| CID3242510 b99f4e0e3deb2a2cc8f77f23f41fa003 [R]C(=O)OC 4 1 c861a3a0b5e6510edb21465393a75d86 | |
| CID3242510 6da339ab75c3d1d1427cad3f0e50c2ef [R]c1ccccc1[R] 6 2 101f8b204bb40dc4b226756399f2e961 | |
| CID3242510 5f9ef1c568c527d4afcaf223bb21c97f [R]C1CC(=NO1)c2ccc(F)cc2 12 1 31d97d94d1d090715db8394a82b30d34 | |
| CID3242510 1e2396bdd17c15f3e40fe55ca74afde9 [R]NC(=O)C1CC(=NO1)[R] 8 2 dc742b64ff87100f0e7c996cc4e0eb4c | |
| CID3242510 3c0fc5320fc164c8a112828272f6789f [R]C(=O)Nc1ccccc1[R] 9 2 c5b1797345f9d08efb357f569eecf2bf | |
| CID3242510 6e79403be5ab3ccde2532ab8e8bf0f12 [R]c1ccccc1C(=O)OC 10 1 aa205a7c420e4fbf10c2a7783977f50f | |
| CID3242979 8fcbeb6fa1f9477222260e55d8842991 [R]C1CC(=NO1)[R] 5 2 c571bc164230bf12d923545a1a7508a6 | |
| CID3242979 94ccb5b2d910c40f747b3924f0f20776 [R]NC(=O)[R] 3 2 1d4ac5b6330c45d3615cdfc2bc7af0b4 | |
| CID3242979 6e7c97f191099b744eb97abc7f380953 [R]c1cccc([R])c1 6 2 6311f51a0b08df6893c9b66a602d6d03 | |
| CID3242979 777775604b353e82c360d5173799e85d [R]c1cc([R])c([R])c([R])c1 6 4 0d599cf4a73f109970061d68a4d9be15 | |
| CID3242979 1e2396bdd17c15f3e40fe55ca74afde9 [R]NC(=O)C1CC(=NO1)[R] 8 2 227dd16c3c10f418ae34f2e011eaec3a | |
| CID3242979 7056e805b487e71ef047203a61fd7abe [R]C1CC(=NO1)c2cccc([R])c2 11 2 7d51d8292814ebe3fda87bcc24a55166 | |
| CID3242979 33688dfa24816ee1fcdc5c587ef6d3dc [R]C(=O)Nc1cc([R])c([R])c([R])c1 9 4 f3643781f3ceffdd1b0ed777ed663a36 | |
| CID3242979 7e324ed6d41b9bfed72f9fd671b149d3 [R]C(=O)Nc1cc([R])c([R])c(OC)c1 11 3 86832d8f333d09334fb96ab5ba5c9cf0 | |
| CID3242979 7e324ed6d41b9bfed72f9fd671b149d3 [R]C(=O)Nc1cc([R])c([R])c(OC)c1 11 3 86832d8f333d09334fb96ab5ba5c9cf0 | |
| CID3242979 28ec093bfb4e6f95762af048d84c9dc3 [R]C(=O)Nc1cc([R])c(OC)c([R])c1 11 3 86832d8f333d09334fb96ab5ba5c9cf0 | |
| CID3242979 5e42d837111a8d68715c391462e82854 [R]c1cc([R])c([R])c(OC)c1 8 3 b69b6116a1d08822cac53c14dbb76331 | |
| CID3242979 02267be7570384ca37c79cabce3f79fc [R]c1cc(OC)c([R])c(OC)c1 10 2 538085ffcfc59d92cf23c2075a19f0bb | |
| CID3242979 c76a823c591b9b51389cede68b3da393 [R]c1cc(OC)c(OC)c(OC)c1 12 1 a4e4d90e2237e60c5e2391de8771b8e4 | |
| CID3242979 0af2dd65fb3161488f766e864d0e8248 [R]c1cc([R])c(OC)c(OC)c1 10 2 538085ffcfc59d92cf23c2075a19f0bb | |
| CID3242979 5e42d837111a8d68715c391462e82854 [R]c1cc([R])c([R])c(OC)c1 8 3 b69b6116a1d08822cac53c14dbb76331 | |
| CID3242979 0af2dd65fb3161488f766e864d0e8248 [R]c1cc([R])c(OC)c(OC)c1 10 2 538085ffcfc59d92cf23c2075a19f0bb | |
| CID3242979 7dc9c6cb16d0c93c71cc979e0d89a7ae [R]c1cccc(OC)c1 8 1 cbfccf26bcfa01a7bbf50fc413b3b3c2 | |
| CID3242979 c3b61895b9c40c70295521ee1efd7073 [R]c1cc([R])c(OC)c([R])c1 8 3 b69b6116a1d08822cac53c14dbb76331 | |
| CID3243409 bbe7b0918349051b84a2ac651db7068f [R]c1ccc(F)cc1 7 1 40025d98004f0739f5c2012c024cb27e | |
| CID3243409 8fcbeb6fa1f9477222260e55d8842991 [R]C1CC(=NO1)[R] 5 2 3bdeacae1f7176b37f3d861733e03490 | |
| CID3243409 94ccb5b2d910c40f747b3924f0f20776 [R]NC(=O)[R] 3 2 23ccdba6582361c09d24b86500a5890a | |
| CID3243409 4164124d4a967557812e06a753509776 [R]c1ccc([R])cc1 6 2 5f9426da999c413a0d923df5590390a9 | |
| CID3243409 1e2396bdd17c15f3e40fe55ca74afde9 [R]NC(=O)C1CC(=NO1)[R] 8 2 e83c76c9cc11a0036c67218055615880 | |
| CID3243409 08db99b5450c03428530da26bc589adf [R]C(=O)Nc1ccc([R])cc1 9 2 738c3c6b5cd353e9725696a8bed55059 | |
| CID3243409 fef83f3fa32653176c70bb96187d0f39 [R]C(=O)Nc1ccc(cc1)C#N 11 1 5f9ef1c568c527d4afcaf223bb21c97f | |
| CID3243409 d414ebdd71208f56bc45a80a0a8e3124 [R]c1ccc(cc1)C#N 8 1 aa205a7c420e4fbf10c2a7783977f50f | |
| CID3243453 24997595c9966aba5bd8f55eacd8a841 [R]N1C(=Nc2[nH]ncc2C1=O)[R] 10 2 17cd02eb4a46586ac6534c803810e1a8 | |
| CID3243453 94ccb5b2d910c40f747b3924f0f20776 [R]NC(=O)[R] 3 2 3e81dc876f263b104dcd3bad9280048c | |
| CID3243453 0f226bd7d5835e982c9535e9517158c8 [R]c1cc(C)[nH]n1 6 1 6902b9bdc67b13edbaf911fa7bdda80d | |
| CID3243453 4164124d4a967557812e06a753509776 [R]c1ccc([R])cc1 6 2 7deeaa7fda2aaeb43d847b9932711ece | |
| CID3243453 adf2bc81282794ccff733cae00b8f17d [R]NC(=O)CS[R] 5 2 fd9f800980adfc1235fce707a40b080f | |
| CID3243453 1c8f1342fd4b742c3c074bcc9632d320 [R]CC(=O)N[R] 4 2 fe63150ef281b1e4b2ef4ae48ed9c31e | |
| CID3243453 bd199dcf2771cea466e2d205c34476b5 [R]SC1=Nc2[nH]ncc2C(=O)N1[R] 11 2 4cfc601d38de087206b1ad833f5db008 | |
| CID3243453 577c0c8f931b6e486961db668d5acba6 [R]CSC1=Nc2[nH]ncc2C(=O)N1[R] 12 2 7a5f804d933dbc4d0497128ac96edb1a | |
| CID3243453 d9fec27b9a8f7083e5baec4bc5c09b3b [R]SCC(=O)Nc1cc(C)[nH]n1 11 1 51048a4dbe70c4ced0409a3e19051733 | |
| CID3243453 254bde6aca3f85a64b8db791724edc2c [R]C(=O)Nc1cc(C)[nH]n1 9 1 2634e2e5619d979072278f1f938afbd8 | |
| CID3243453 ecf6defc926a9f34f0da005f8197a9fe [R]CC(=O)Nc1cc(C)[nH]n1 10 1 97cb1413961056958d37eee41538781e | |
| CID3243453 b1d44544a658e0f84213d92819559ed9 [R]c1ccc(CC)cc1 8 1 909db7f1d9775888e64a42910c5fef03 | |
| CID3349764 c3d90dee44e7363b54950ba04d2445dc [R]c1oc2ccccc2c1[R] 9 2 80da4309452ec0e4671ba8a9016cefa0 | |
| CID3349764 aa57f10d408973d56fd07c6f8592e918 [R]c1occc1 5 1 04c5f91a3e254f5f3f358a43cc43719b | |
| CID3349764 94ccb5b2d910c40f747b3924f0f20776 [R]NC(=O)[R] 3 2 738317f8eb66638640c203ce09e3b7bd | |
| CID3349764 cd41a357317ad2cdfe7c3be281f74ea9 [R]C(=O)N 3 1 3b4746f2cdf2d7bf9f8f3ff98d0b62b4 | |
| CID3349764 4e4351044fd9ba010bb3092ab9ede259 [R]NC(=O)c1occc1 8 1 69f9cdfa7b1b73c8f34681f779d73a10 | |
| CID4907320 280cad05f0ac04d13bef256ea87219f7 [R]N1C(=O)Nc2ccccc2C1=O 12 1 99858e94a6329fda3f16b7c0ddf216a5 | |
| CID4907320 e1c407781f09f5685045d2098372f629 [R]N1CCN([R])CC1 6 2 facef9e9cd374eac0036a699d038c91b | |
| CID4907320 7acbe9d24d1580f5db2a2cfbf8d22b0e [R]C1CCC([R])CC1 6 2 3ac4ac0967831a690053d1b8a96e9159 | |
| CID4907320 40ff37b23ab7e50f673813778a2799c9 [R]c1ccccc1 6 1 c0f5e2ba4b2413595cd18c27f7f97423 | |
| CID4907320 fff923760e9b5128c2bbc84afdecf548 [R]N1CCN(CC1)C(=O)[R] 8 2 afec3db085c422968906aaef6100bdc2 | |
| CID4907320 798d057b977bba528dfee47da909927b [R]C1CCC(CC1)C(=O)[R] 8 2 752318a18c39ef7ee2b11bc50efeff12 | |
| CID4907320 8c45a2b47e38b543b14829e96b0d4a05 [R]CC1CCC(CC1)C(=O)[R] 9 2 100a8ebac62c3c59f7e2161df12265f6 | |
| CID4907320 a2094151dbac92354741f5c9a051b8ec [R]N1CCN(CC1)c2ccccc2 12 1 3347678df1f43126d1f580ccef63417d | |
| CID4907320 ad93b521cacb9f4cc7988a6ae5e37ca8 [R]CC1CCC([R])CC1 7 2 041860a24a7990aa70541c1047b8647a | |
| CID5144290 280cad05f0ac04d13bef256ea87219f7 [R]N1C(=O)Nc2ccccc2C1=O 12 1 4319c30fe787c931b85a3781556263ab | |
| CID5144290 94ccb5b2d910c40f747b3924f0f20776 [R]NC(=O)[R] 3 2 b6566da3a738cd251fd8c16d8617acbd | |
| CID5144290 4164124d4a967557812e06a753509776 [R]c1ccc([R])cc1 6 2 6e9d5e9764622d15c82263116272bb26 | |
| CID5144290 f800a31d76f3adad5c308bf679462019 [R]CCC[R] 3 2 8e49626130540113b761191a63db4d7a | |
| CID5144290 727a15facad903cdffc729e11c1e1840 [R]CCCOC 5 1 850c39a875d8c91c949b76b532a2fbe1 | |
| CID5144290 20ee8831389e5cc9183462d172043d60 [R]C(=O)NCCCOC 8 1 e9fad6f69c78c7152b6e96b019286557 | |
| CID5144290 f4b8448d229b3c026b32525454c8efa7 [R]CCCNC(=O)[R] 6 2 3bac313e3a1407bc938d7d093e2750d4 | |
| CID5144290 3b7bea15e513aba897198f52a17edff6 [R]NC(=O)c1ccc([R])cc1 9 2 de8b70fbb034be06488813723d029b1e | |
| CID5144290 6399fad20d12081cf48799f82803c146 [R]Cc1ccc(cc1)C(=O)N[R] 10 2 274ac33f2cbd3ae00a8b8a4cb1006172 | |
| CID5144290 9644b27ca8bb92adf1f7bed5019cabf7 [R]CCCNC(=O)c1ccc([R])cc1 12 2 0abca81c6d847daf5669935c706fae95 | |
| CID5144290 ea85b643fa324a93ea4e2f512edbd8b3 [R]Cc1ccc([R])cc1 7 2 bfdbde77200726474e128b2b2f8024fa | |
| CID5309978 3ca7fd3b49373186f87380d3dc0c9cd0 [R]c1ccsc1[R] 5 2 fdb92e74d3c73ef3d422b61c91f042cf | |
| CID5309978 94ccb5b2d910c40f747b3924f0f20776 [R]NC(=O)[R] 3 2 ffb94dc07b57376c47726bbba123ad56 | |
| CID5309978 3cd0a4a42541970c14751da25e243654 [R]C(=O)NC 4 1 44d7b52846c08746361bd059da493136 | |
| CID5309978 40ff37b23ab7e50f673813778a2799c9 [R]c1ccccc1 6 1 63a2ecd9be3b43c449e24dda1ca19d99 | |
| CID5309978 8d95afec2a293f6a875cc644d8e1a45d [R]C(=O)Nc1sccc1[R] 8 2 0ea9e766a97c9829e50cf56a9f9539b1 | |
| CID5310086 3ca7fd3b49373186f87380d3dc0c9cd0 [R]c1ccsc1[R] 5 2 3c7914ffcdbae59a402cceb80b40e56c | |
| CID5310086 f5c23d1f058c1f289dab267649113b64 [R]C1=COCCO1 6 1 f37ba0471aa825e1b0dbbdbe8c2b39e7 | |
| CID5310086 b99f4e0e3deb2a2cc8f77f23f41fa003 [R]C(=O)OC 4 1 55167b490a7cb21c8eb9fe300a9e33c8 | |
| CID5310086 94ccb5b2d910c40f747b3924f0f20776 [R]NC(=O)[R] 3 2 877d1b74bfe6e370cc7caa8d7aa6bef4 | |
| CID5310086 8d95afec2a293f6a875cc644d8e1a45d [R]C(=O)Nc1sccc1[R] 8 2 22d4b8440aebd4cf263d0e605ffdcdc2 | |
| CID6398908 b99f4e0e3deb2a2cc8f77f23f41fa003 [R]C(=O)OC 4 1 67f09a861f61517138ddaa8875f0df3b |
This file contains bidirectional Unicode text that may be interpreted or compiled differently than what appears below. To review, open the file in an editor that reveals hidden Unicode characters.
Learn more about bidirectional Unicode characters
| Hashkey Smiles Size NumAttachments FID | |
| 40ff37b23ab7e50f673813778a2799c9 [R]c1ccccc1 6 1 FRG0000001 | |
| c230b0bb3e580833ad3d825b9444a5c6 [R]C(=O)O 3 1 FRG0000002 | |
| db7c0f061564c242acd9b97c8c24b307 [R]CCS[R] 3 2 FRG0000003 | |
| 146a834c5468a9ff9932e1c930c59e4b [R]SCCC(=O)O 6 1 FRG0000004 | |
| 5315ba718f2107f5017cb735faed8afd [R]CCC(=O)O 5 1 FRG0000005 | |
| 2563b58ed23b5c3b1527083bc2ee56e6 [R]OC(=O)[R] 3 2 FRG0000006 | |
| 94ccb5b2d910c40f747b3924f0f20776 [R]NC(=O)[R] 3 2 FRG0000007 | |
| 20909a7efda6e6dce692a77bc67c48c1 [R]c1ncc([R])c(N)n1 7 2 FRG0000008 | |
| 6da339ab75c3d1d1427cad3f0e50c2ef [R]c1ccccc1[R] 6 2 FRG0000009 | |
| adf2bc81282794ccff733cae00b8f17d [R]NC(=O)CS[R] 5 2 FRG0000010 | |
| 8b87e9872a00680ee0842d5d0a5f290d [R]C(=O)OCC 5 1 FRG0000011 | |
| 1c8f1342fd4b742c3c074bcc9632d320 [R]CC(=O)N[R] 4 2 FRG0000012 | |
| 7a69ae1e38969cbfebdba1750950b49b [R]Sc1ncc([R])c(N)n1 8 2 FRG0000013 | |
| f36abe78b05bc76ca84bf6dff89363a7 [R]OC(=O)c1cnc(S[R])nc1N 11 2 FRG0000014 | |
| 65f74ac7eb94744fcf92898d5a6ce58f [R]CSc1ncc(C(=O)O[R])c(N)n1 12 2 FRG0000015 | |
| 949962efe3c311f46962e09306044cd4 [R]CSc1ncc([R])c(N)n1 9 2 FRG0000016 | |
| bec1a087cc7232f64b3219b661c743b1 [R]NC(=O)CSc1ncc([R])c(N)n1 12 2 FRG0000017 | |
| 57e56a72e45f76bf30f0968313642982 [R]SCC(=O)Nc1ccccc1[R] 11 2 FRG0000018 | |
| 9cb112b34ac4ec9f25de9f392a22d1c3 [R]OC(=O)c1ccccc1[R] 9 2 FRG0000019 | |
| fb069326d07744fb31b9532572b9326f [R]OC(=O)c1ccccc1NC(=O)[R] 12 2 FRG0000020 | |
| 0332704df86c0fcfa4886d9e66ddd2d2 [R]c1ccccc1C(=O)OCC 11 1 FRG0000021 | |
| 553ea46d0e7f241e9856a63f2960a5b0 [R]OC(=O)c1cnc([R])nc1N 10 2 FRG0000022 | |
| df48071ced2c344032f9c381cd154252 [R]c1ncc(C(=O)OCC)c(N)n1 12 1 FRG0000023 | |
| 3c0fc5320fc164c8a112828272f6789f [R]C(=O)Nc1ccccc1[R] 9 2 FRG0000024 | |
| b4a241675c217a2e096a5c796f9ed5f5 [R]CC(=O)Nc1ccccc1[R] 10 2 FRG0000025 | |
| b99f4e0e3deb2a2cc8f77f23f41fa003 [R]C(=O)OC 4 1 FRG0000026 | |
| 4e11afcb7f861429aca649aaf168694c [R]C1CCN([R])CC1 6 2 FRG0000027 | |
| b577ac26aa3bd7b75f22800b57854927 [R]c1ccccc1C 7 1 FRG0000028 | |
| c6731fe86b6c867e456bad1ab01466a9 [R]N1CCC(CC1)NC(=O)[R] 9 2 FRG0000029 | |
| c8661c9810a5656c690ac61cae814a29 [R]CN1CCC(CC1)NC(=O)[R] 10 2 FRG0000030 | |
| 17933fa20cde572b6a227f2d230e2527 [R]NC(=O)c1ccccc1C 10 1 FRG0000031 | |
| 1b07b84eacfc0b1cbd7ec7bc34816e5b [R]NC(=O)CN1CCC([R])CC1 10 2 FRG0000032 | |
| 6e79403be5ab3ccde2532ab8e8bf0f12 [R]c1ccccc1C(=O)OC 10 1 FRG0000033 | |
| 132bcc13879dceff1a97d1eeec5f47cd [R]CN1CCC([R])CC1 7 2 FRG0000034 | |
| 1182f5a434f5ca9647925fe1b4fefb96 [R]c1ccc(C)cc1 7 1 FRG0000035 | |
| 1faa2e983c36de3279bb18e398fa86a2 [R]NC(=O)c1ccc(C)cc1 10 1 FRG0000036 | |
| aa16c7a7dca9b0411a328f76907dc84b [R]c1ccnc([R])c1[R] 6 3 FRG0000037 | |
| 0c63224f62fb392c60f52371e7672c16 [R]c1cccnc1 6 1 FRG0000038 | |
| e74a1a643b405067f8373b79e66c039d [R]Nc1ccnc([R])c1[R] 7 3 FRG0000039 | |
| 1a1e6a86ef0c63b3b0409aa29e78d1a4 [R]Nc1ccnc(N[R])c1[R] 8 3 FRG0000040 | |
| 4460bf4aaba15748e4445edcd996ceab [R]Nc1ccnc(N[R])c1C#N 10 2 FRG0000041 | |
| 4d6ad54abdb41d4f832a910e46569dd7 [R]CNc1ccnc(N[R])c1C#N 11 2 FRG0000042 | |
| 0d2e6bdf3cf84f993c1556669a8544c7 [R]CNc1nccc(N[R])c1C#N 11 2 FRG0000043 | |
| d2edf82a8fcc978d8b34c5b6e50abffc [R]CNc1ccnc(N[R])c1[R] 9 3 FRG0000044 | |
| e062d547c9c1495b3ce8e812936736f8 [R]CNc1ccnc(NC[R])c1[R] 10 3 FRG0000045 | |
| 558954ef7d9b51fcfc302179de2acbbe [R]CNc1nccc(N[R])c1[R] 9 3 FRG0000046 | |
| a0e97f9bbbdfd5de1b418675c51bf762 [R]Nc1ccnc([R])c1C#N 9 2 FRG0000047 | |
| 4c1f3fa02e79cf35b070e23e05be9253 [R]CNc1ccnc([R])c1C#N 10 2 FRG0000048 | |
| f561e0a13470c42a9b08286f5b4587c7 [R]CNc1ccnc([R])c1[R] 8 3 FRG0000049 | |
| 67dc572f58faef87e6556cf88b49a22a [R]NCc1ccccc1 8 1 FRG0000050 | |
| 1d83b4be805cc7a3dbd58238f66cb058 [R]Nc1nccc([R])c1[R] 7 3 FRG0000051 | |
| c428d1fe9d56e0a97362c311c35bf8b3 [R]Nc1nccc([R])c1C#N 9 2 FRG0000052 | |
| 63d27fecb77a33792f3a4ff7c47f9535 [R]CNc1nccc([R])c1C#N 10 2 FRG0000053 | |
| b9ea5e09387bcf5fd5b00967dfe02be4 [R]CNc1nccc([R])c1[R] 8 3 FRG0000054 | |
| 1b65af14022403f397fb173488a24d02 [R]NCc1cccnc1 8 1 FRG0000055 | |
| 570a0482a263bc5a4dbe618cea60387e [R]c1ccnc([R])c1C#N 8 2 FRG0000056 | |
| c7792eac3fbab9da45cf28757e131cf5 [R]Cc1cccnc1 7 1 FRG0000057 | |
| 644740ac60048143ee0e86d26953489e [R]Cc1ccccc1 7 1 FRG0000058 | |
| cd41a357317ad2cdfe7c3be281f74ea9 [R]C(=O)N 3 1 FRG0000059 | |
| b8edb181ba5993d221071ff97cef9af7 [R]c1ccc([R])c([R])c1 6 3 FRG0000060 | |
| a93d78ee7f73f76b489bd8a77e92c65a [R]C(=C([R])C)[R] 3 3 FRG0000061 | |
| 59b597bdca2d6ce05597650fffd22a06 [R]\C(=C(\[R])/C(=O)N)\C 6 2 FRG0000062 | |
| 2b9b9124c08296c9fed9ae81e11f0126 [R]N\C(=C(\[R])/C(=O)N)\C 7 2 FRG0000063 | |
| a3d62a6aba798a60fb58842d10d08bc2 [R]N\C(=C(\C#N)/C(=O)N)\C 9 1 FRG0000064 | |
| 138607086988192351de9f08309a0dd0 [R]CN\C(=C(\[R])/C(=O)N)\C 8 2 FRG0000065 | |
| 8d5d61c7bbbf29d1ca9ee7b7c285c173 [R]\C(=C(\C#N)/C(=O)N)\C 8 1 FRG0000066 | |
| 52d9dc8b5c127a8c2271a2f616a12945 [R]CNC(=C([R])[R])C 5 3 FRG0000067 | |
| 5d7bd41f3d5e8a78cd85a3e0eb515ce2 [R]CN\C(=C(/[R])\C#N)\C 7 2 FRG0000068 | |
| 490ab1f0eacd310f54845f7700b58ef3 [R]NC(=C([R])[R])C 4 3 FRG0000069 | |
| 675b9217654d8f1726c6000e97898db9 [R]N\C(=C(/[R])\C#N)\C 6 2 FRG0000070 | |
| cd6742f774bcc36f54b5049f2ab13074 [R]\C(=C(/[R])\C#N)\C 5 2 FRG0000071 | |
| 2af9016e0c2c258faf48da5205783cfb [R]c1ccc([R])c(OC)c1 8 2 FRG0000072 | |
| c282d4b5e744abde59fd562cf8229dda [R]Cc1ccc([R])c(OC)c1 9 2 FRG0000073 | |
| 898878b148c9c8e80633531f07a3a47f [R]c1ccc(OC)c([R])c1 8 2 FRG0000074 | |
| e35c1ad1f40a9080e226b3807171c9dc [R]Cc1ccc(OC)c([R])c1 9 2 FRG0000075 | |
| 6d8716f54d2b13b55fdcc5374a0050dc [R]NCc1ccc([R])c([R])c1 8 3 FRG0000076 | |
| 2ac191a4a0033794abbc677e7ed89dcf [R]Cc1ccc([R])c([R])c1 7 3 FRG0000077 | |
| a3a4052f21a7a4058dcdb302e6b9f33e [R]N1C=C([R])C=C(Br)C1=O 8 2 FRG0000078 | |
| 35065791899b93ce68fc2efe276d6bc5 [R]c1ccc2OCOc2c1 9 1 FRG0000079 | |
| 2c33d2f7ffc88e627cbb17bafd382a11 [R]CN1C=C([R])C=C(Br)C1=O 9 2 FRG0000080 | |
| 450d51b4d5e5e12d248540582bd747a2 [R]Cc1ccc2OCOc2c1 10 1 FRG0000081 | |
| de9c513fc202e8f20cbcae1fa2848475 [R]c1ccc(OC)c(OC)c1 10 1 FRG0000082 | |
| d923c497ad6fa2bfb97bee8785cc2f36 [R]Cc1ccc(OC)c(OC)c1 11 1 FRG0000083 | |
| cf53f11d5494c490e6a688dd860241a4 [R]SC([R])C 3 2 FRG0000084 | |
| 09ba8023719be9deab8b4b9aae5ecb5b [R]SC(C)C(=O)O 6 1 FRG0000085 | |
| a669a21ecf9e7b0ab276af5d124f4a0b [R]C(C)C(=O)O 5 1 FRG0000086 | |
| 982d1ba5cb047d28e66a049dc43d1507 [R]CCC 3 1 FRG0000087 | |
| 2e1a5014d8b0810404cf238f525011d6 [R]c1cccc(F)c1 7 1 FRG0000088 | |
| 4f4f233f007239425e6ea1c2ec2f6d8c [R]n1cccn1 5 1 FRG0000089 | |
| d59f0ac5ac83d558f48f25483c1531b1 [R]c1cc([R])ncn1 6 2 FRG0000090 | |
| e2ee0df7d3bd7764677e5b818755dfbc [R]Nc1cccc(F)c1 8 1 FRG0000091 | |
| 508d5d6331c53c7edff2d69c02f2ed50 [R]Nc1cc([R])ncn1 7 2 FRG0000092 | |
| 3a01fbaa2c834734cf77e5a8568eee41 [R]c1oc(Br)cc1 6 1 FRG0000093 | |
| 4d81ccb632ba681dd6842d1f3ffe0a77 [R]c1cccc(Cl)c1[R] 7 2 FRG0000094 | |
| e1c407781f09f5685045d2098372f629 [R]N1CCN([R])CC1 6 2 FRG0000095 | |
| b63e309b66092bec1ae7cd60ecefaa39 [R]NC(=O)c1oc(Br)cc1 9 1 FRG0000096 | |
| eba6fac994bdec9ba0a7dceb7d75059d [R]C(=O)Nc1cccc(Cl)c1[R] 10 2 FRG0000097 | |
| 4280ce38dd08ade4082c8a6e678006eb [R]N1CCN(CC)CC1 8 1 FRG0000098 | |
| c3d90dee44e7363b54950ba04d2445dc [R]c1oc2ccccc2c1[R] 9 2 FRG0000099 | |
| e70f6cf23e5b4a1d4c852d424dabd6ff [R]OCC 3 1 FRG0000100 | |
| e6dd1f3cb235024deb09e8adea218003 [R]C(=O)Nc1c([R])oc2ccccc12 12 2 FRG0000101 | |
| 69f9cdfa7b1b73c8f34681f779d73a10 [R]c1c(oc2ccccc12)C(=O)N 12 1 FRG0000102 | |
| a896f422cdda3cad1f2f214e1ead3255 [R]Oc1cc([R])ccc1[R] 7 3 FRG0000103 | |
| 03db71ca1ace27a3cfe81ab99db0eb79 [R]Oc1ccc([R])cc1O[R] 8 3 FRG0000104 | |
| 7f58abb2f25dff6237392f190be54833 [R]Cc1ccc(O[R])c(O[R])c1 9 3 FRG0000105 | |
| c7f9092954ac9772b82b8cb76aeb8e40 [R]NC(=O)Cc1ccc(O[R])c(O[R])c1 12 3 FRG0000106 | |
| 48aeda531b489db27b3c725170f0b644 [R]Cc1ccc(O[R])c(OCC)c1 11 2 FRG0000107 | |
| e5473d277007004721e62ee5e4d6feb7 [R]Cc1ccc(OCC)c(O[R])c1 11 2 FRG0000108 | |
| 6c12340861ea1581d2bf283f173bb059 [R]Oc1ccc([R])cc1OCC 10 2 FRG0000109 | |
| 295165e2f42bd48faecc8c662da13484 [R]c1ccc(OCC)c(OCC)c1 12 1 FRG0000110 | |
| 590d4ff85a1696aaaa27da2011b03407 [R]Oc1cc([R])ccc1OCC 10 2 FRG0000111 | |
| 0f1bd95eeef93ecb43f5d6540935b90e [R]Cc1ccc([R])c(O[R])c1 8 3 FRG0000112 | |
| 2645596311426e7a9de50d78e454e642 [R]NC(=O)Cc1ccc([R])c(O[R])c1 11 3 FRG0000113 | |
| 2b343ff26a32e3a34876cbb24ae7c864 [R]Cc1ccc([R])c(OCC)c1 10 2 FRG0000114 | |
| 7a3888885b840aff9f8c10947c6adfd6 [R]c1ccc([R])c(OCC)c1 9 2 FRG0000115 | |
| d9c569d63443d5dbb9ff9fbf46b96cbc [R]Oc1ccc([R])cc1[R] 7 3 FRG0000116 | |
| f531e57f70bd69248a78b1766414b0ce [R]Cc1ccc(O[R])c([R])c1 8 3 FRG0000117 | |
| 9d398a52f8d9e86a6598aea688c5a441 [R]NC(=O)Cc1ccc(O[R])c([R])c1 11 3 FRG0000118 | |
| 64a5a985dac573b8bcfd2020d0c46a7a [R]Cc1ccc(OCC)c([R])c1 10 2 FRG0000119 | |
| c4520a611ae4f444a0bc19e4e1a78089 [R]c1ccc(OCC)c([R])c1 9 2 FRG0000120 | |
| 1114f1502c1c5f37b43cd2edd1160ff8 [R]NC(=O)Cc1ccc([R])c([R])c1 10 3 FRG0000121 | |
| 4a0dd495933856eef7724b025449c0b3 [R]c1cc([R])c([R])s1 5 3 FRG0000122 | |
| aa57f10d408973d56fd07c6f8592e918 [R]c1occc1 5 1 FRG0000123 | |
| 8ad561bface07875535759b9ce1faebe [R]c1cc(C(=O)N)c([R])s1 8 2 FRG0000124 | |
| 10e91cd35458d498255db33e0ae9d1b4 [R]C(=O)Nc1sc([R])cc1C(=O)N 11 2 FRG0000125 | |
| eff25640dafc98102e26fe301ea44dac [R]Cc1cc(C(=O)N)c([R])s1 9 2 FRG0000126 | |
| 2b6ea346a9850e5115bd414865710f77 [R]C(=O)Nc1sc([R])cc1[R] 8 3 FRG0000127 | |
| 5a8873c73cc130ce65587050f2d5e022 [R]Cc1cc([R])c(NC(=O)[R])s1 9 3 FRG0000128 | |
| 3bb5381058460149342d37d452691600 [R]Cc1cc([R])c([R])s1 6 3 FRG0000129 | |
| 4e4351044fd9ba010bb3092ab9ede259 [R]NC(=O)c1occc1 8 1 FRG0000130 | |
| d7409f5391b48331565ab0de1680103d [R]c1csc(C)n1 6 1 FRG0000131 | |
| 24997595c9966aba5bd8f55eacd8a841 [R]N1C(=Nc2[nH]ncc2C1=O)[R] 10 2 FRG0000132 | |
| bd199dcf2771cea466e2d205c34476b5 [R]SC1=Nc2[nH]ncc2C(=O)N1[R] 11 2 FRG0000133 | |
| b64de3e64d0f0d9fc6848d3b973eef80 [R]SCc1csc(C)n1 8 1 FRG0000134 | |
| 62d788ecc76e4888e42f89be691f887f [R]Cc1csc(C)n1 7 1 FRG0000135 | |
| 64c71197c21e5522df9060fd9374e83b [R]N1CCOCC1 6 1 FRG0000136 | |
| 3ca7fd3b49373186f87380d3dc0c9cd0 [R]c1ccsc1[R] 5 2 FRG0000137 | |
| 777775604b353e82c360d5173799e85d [R]c1cc([R])c([R])c([R])c1 6 4 FRG0000138 | |
| 8d95afec2a293f6a875cc644d8e1a45d [R]C(=O)Nc1sccc1[R] 8 2 FRG0000139 | |
| 73fc69a0eb6e5c111e6b1fd4ec0aab81 [R]C(=O)Nc1sccc1C(=O)N 11 1 FRG0000140 | |
| ed35caa2453f752019f6e002a01394a8 [R]CC(=O)Nc1sccc1[R] 9 2 FRG0000141 | |
| 8578d8772ab6c795a10660e14ae3c16e [R]c1sccc1C(=O)N 8 1 FRG0000142 | |
| 5e42d837111a8d68715c391462e82854 [R]c1cc([R])c([R])c(OC)c1 8 3 FRG0000143 | |
| 02267be7570384ca37c79cabce3f79fc [R]c1cc(OC)c([R])c(OC)c1 10 2 FRG0000144 | |
| 820ce97b48fb8c34764fdc25c7355c65 [R]Cc1cc(OC)c([R])c(OC)c1 11 2 FRG0000145 | |
| 0af2dd65fb3161488f766e864d0e8248 [R]c1cc([R])c(OC)c(OC)c1 10 2 FRG0000146 | |
| 15e1b9c97aa0978906e0b4a20be91ab2 [R]Cc1cc([R])c(OC)c(OC)c1 11 2 FRG0000147 | |
| 7615e9d1cf51481b809a334696bdac1f [R]Cc1cc([R])c([R])c(OC)c1 9 3 FRG0000148 | |
| c3b61895b9c40c70295521ee1efd7073 [R]c1cc([R])c(OC)c([R])c1 8 3 FRG0000149 | |
| 07b54b285c0a3a2bedc32ffb85a13e17 [R]Cc1cc([R])c(OC)c([R])c1 9 3 FRG0000150 | |
| 6cf2fbdf8be2be95dfa668d71b2e1aef [R]NC(=O)Cc1cc([R])c([R])c([R])c1 10 4 FRG0000151 | |
| d7bde0391745eef431de8cc1a9bc4a30 [R]Cc1cc([R])c([R])c([R])c1 7 4 FRG0000152 | |
| 5bbb8410ab155c56222153df89c4109f [R]N([R])S(=O)(=O)[R] 4 3 FRG0000153 | |
| 4a9b05abb892fed9970df98452385179 [R]c1ccc2nc([R])[nH]c2c1 9 2 FRG0000154 | |
| 88e8d646a409a3a47522d520919494fb [R]c1n[nH]c2ccccc12 9 1 FRG0000155 | |
| 11fb59c537194ddabf77cfb14dc0c98f [R]N(CC)S(=O)(=O)[R] 6 2 FRG0000156 | |
| efe652350abaa773ec07d9574d9559c2 [R]S(=O)(=O)N(CC)CC 8 1 FRG0000157 | |
| 74898da880c05406046db37731d6260c [R]COC(=O)[R] 4 2 FRG0000158 | |
| 539e1d0db4d63da7c83de72682e07244 [R]OC(=O)c1n[nH]c2ccccc12 12 1 FRG0000159 | |
| 388df9a35ed3dd2feb3180d4f2dcf076 [R]Cc1nc2ccc([R])cc2[nH]1 10 2 FRG0000160 | |
| ae7cd6dfac77300c9a7c2a9e31b6c9ed [R]S(=O)(=O)[R] 3 2 FRG0000161 | |
| 9d20868abe811ed72b8907c6e6814226 [R]N1CCCC1 5 1 FRG0000162 | |
| 4164124d4a967557812e06a753509776 [R]c1ccc([R])cc1 6 2 FRG0000163 | |
| 1615648c547b212aed37ac41eb8677c9 [R]NC(=O)COC(=O)[R] 7 2 FRG0000164 | |
| cbfde57cbacd5c5f82482a0c2c0afbeb [R]S(=O)(=O)N1CCCC1 8 1 FRG0000165 | |
| 661e15be7c43b7d726940fd8acd214fc [R]c1ccc(cc1)S(=O)(=O)[R] 9 2 FRG0000166 | |
| 4d29576ab70721ff9b0c2afd12d45e3c [R]C(=O)Nc1ccc(cc1)S(=O)(=O)[R] 12 2 FRG0000167 | |
| 08db99b5450c03428530da26bc589adf [R]C(=O)Nc1ccc([R])cc1 9 2 FRG0000168 | |
| 265ee31f3bd71cdfa714c0259b134ce4 [R]CC(=O)Nc1ccc([R])cc1 10 2 FRG0000169 | |
| 1f2ca5fa50abd32418ce8479ef496a49 [R]N1CCCCC1 6 1 FRG0000170 | |
| 9c114cee4d02f92bcdff3a7836e07dec [R]S(=O)(=O)N1CCCCC1 9 1 FRG0000171 | |
| 3b7ea99dc991d61d1dd20299fabf0452 [R]NC(=O)c1ccc(cc1)S(=O)(=O)[R] 12 2 FRG0000172 | |
| 3b7bea15e513aba897198f52a17edff6 [R]NC(=O)c1ccc([R])cc1 9 2 FRG0000173 | |
| 1900051bb5332de8822612ea9f672e97 [R]N1C(=Nc2ccccc2C1=O)[R] 11 2 FRG0000174 | |
| c31f7927e1ad6441d53e8c50bbfc6725 [R]CCCO 4 1 FRG0000175 | |
| 960a0f88a271a8a2e76844bb674b322b [R]SC1=Nc2ccccc2C(=O)N1[R] 12 2 FRG0000176 | |
| d1869c0b0410570a2d1525cce3478e82 [R]SCC(=O)Nc1sccc1[R] 10 2 FRG0000177 | |
| 438a7db88045fbe38da9000d1efa08c9 [R]CC(=O)Nc1sccc1C(=O)N 12 1 FRG0000178 | |
| 9ad05de67e509ed28043152f0b67dd95 [R]N1C(=Nc2sc(C)c(C)c2C1=O)[R] 12 2 FRG0000179 | |
| 1deb7cd7f65a68f03cbd1660b3fe65c0 [R]CC=C 3 1 FRG0000180 | |
| ec7d694c9f59163e38083a3c5accd851 [R]N1C(=S)Nc2ccccc2C1=O 12 1 FRG0000181 | |
| 7acbe9d24d1580f5db2a2cfbf8d22b0e [R]C1CCC([R])CC1 6 2 FRG0000182 | |
| d8aa80cc7cf96e274c68c5cca70dbeb5 [R]CCNC(=O)[R] 5 2 FRG0000183 | |
| 5bde16c7f6e79d6e5df1e43541df0c99 [R]C(=O)NCCOC 7 1 FRG0000184 | |
| 0e82ca938f8827db4f845afe45972967 [R]CCOC 4 1 FRG0000185 | |
| 129ff0b95cd03c4d40cb217ad8fd373b [R]NC(=O)C1CCC([R])CC1 9 2 FRG0000186 | |
| f42882de9be90903adf8e8bce57e5f79 [R]CC1CCC(CC1)C(=O)N[R] 10 2 FRG0000187 | |
| 2decf05f43a4613538a2f7bd4863c128 [R]CCNC(=O)C1CCC(C[R])CC1 12 2 FRG0000188 | |
| a426f5c275feeb0454f6c6c68b635100 [R]CCNC(=O)C1CCC([R])CC1 11 2 FRG0000189 | |
| ad93b521cacb9f4cc7988a6ae5e37ca8 [R]CC1CCC([R])CC1 7 2 FRG0000190 | |
| 04a463fee819cb4b30360dbc1a11cb55 [R]c1cccc(Br)c1 7 1 FRG0000191 | |
| 8fcbeb6fa1f9477222260e55d8842991 [R]C1CC(=NO1)[R] 5 2 FRG0000192 | |
| 482c9ba5371cb2445128177a3c9a265a [R]c1cnn([R])c1 5 2 FRG0000193 | |
| 1e2396bdd17c15f3e40fe55ca74afde9 [R]NC(=O)C1CC(=NO1)[R] 8 2 FRG0000194 | |
| d66a967f6506f0b7b9cc2591af6cc9ba [R]C(=O)Nc1cnn([R])c1 8 2 FRG0000195 | |
| f18246b3b8842d47942fd00aba7ad983 [R]C(=O)Nc1cnn(CCC)c1 11 1 FRG0000196 | |
| 5b9193fb09b32d54974876116cde7239 [R]c1cnn(CCC)c1 8 1 FRG0000197 | |
| f4fca06b529baa0a36072ec06e4af440 [R]c1cccs1 5 1 FRG0000198 | |
| 5cd96f7c4836124704977b8899b94423 [R]C1NC(=O)NC1C 7 1 FRG0000199 | |
| d41ce11b8db19ef58f31561bb166a5cb [R]CCCCC[R] 5 2 FRG0000200 | |
| 2f7f05caef4578684c7c682fa5c1ff35 [R]CCCCCC(=O)N[R] 8 2 FRG0000201 | |
| 7979026c220d5ac31d117ef756f0c3fe [R]C(=O)Nc1ccc(C)cc1 10 1 FRG0000202 | |
| b1fb519841649a5d2883632f6d57c26c [R]CCCCCC(=O)NCC[R] 10 2 FRG0000203 | |
| afb6a80a7dc12e95d8793bfc5b3720bc [R]C(=O)NCCc1ccccc1 11 1 FRG0000204 | |
| dba34ca5632e2e1723656cb6009fdafa [R]CCc1ccccc1 8 1 FRG0000205 | |
| bbe7b0918349051b84a2ac651db7068f [R]c1ccc(F)cc1 7 1 FRG0000206 | |
| 259d5c4b05e0489434d305083df59972 [R]C(=O)C 3 1 FRG0000207 | |
| 5c090fd71abb3a3cf1f31256527edf01 [R]c1ccc(cc1)C(=O)C 9 1 FRG0000208 | |
| 1e66aa1ced35748ad2e6f9aa640a3646 [R]\C(=C(/[R])\C(=O)N)\C 6 2 FRG0000209 | |
| bc3c7fd636ada507c6175c899d56b67c [R]N\C(=C(/[R])\C(=O)N)\C 7 2 FRG0000210 | |
| bc0fbd3c7c72f4e9c1c1e9dac99184f4 [R]N\C(=C(/C#N)\C(=O)N)\C 9 1 FRG0000211 | |
| db2ca9e482273e04f76ae620f22405d2 [R]CN\C(=C(/C#N)\C(=O)N)\C 10 1 FRG0000212 | |
| df85ed6ae3ed6bf4ba0087d19fd993ad [R]CN\C(=C(/[R])\C(=O)N)\C 8 2 FRG0000213 | |
| 3818fe5fddb286b6a32f41572322718b [R]\C(=C(/C#N)\C(=O)N)\C 8 1 FRG0000214 | |
| c984252354aefa2e5d364f055eedc0a8 [R]CN\C(=C(\[R])/C#N)\C 7 2 FRG0000215 | |
| b0561e15bcdc556af7e582ae2c7e20ce [R]N\C(=C(\[R])/C#N)\C 6 2 FRG0000216 | |
| 981c96933a877c640cbb5b59243a9f8d [R]\C(=C(\[R])/C#N)\C 5 2 FRG0000217 | |
| 41ce2e1304ce298325a5daf64a73a1ea [R]NCc1cc([R])c([R])c(OC)c1 10 3 FRG0000218 | |
| 0eb26e4da08eabdc5334d28b5866663f [R]NCc1cc([R])c(OC)c([R])c1 10 3 FRG0000219 | |
| 141845b41c4db2b4784096a3751c6fda [R]NCc1cc([R])c([R])c([R])c1 8 4 FRG0000220 | |
| 4916794fa5014840f545e4e6693254e5 [R]c1cnn([R])c1C 6 2 FRG0000221 | |
| 3c394d8c3044c567cb027c6bda2355f2 [R]C1CC(=NO1)c2cnn([R])c2C 11 2 FRG0000222 | |
| 1d01605f8ed43bf4f46202984bc0d155 [R]c1cnn(CC)c1C 8 1 FRG0000223 | |
| 280cad05f0ac04d13bef256ea87219f7 [R]N1C(=O)Nc2ccccc2C1=O 12 1 FRG0000224 | |
| fff923760e9b5128c2bbc84afdecf548 [R]N1CCN(CC1)C(=O)[R] 8 2 FRG0000225 | |
| 981a7d6563bcd4050bb4b0cbfcf798ad [R]C(=O)c1ccc([R])cc1 8 2 FRG0000226 | |
| 5cae5ceb00eea4a36ce2b0c099cfb817 [R]Cc1ccc(cc1)C(=O)[R] 9 2 FRG0000227 | |
| a2094151dbac92354741f5c9a051b8ec [R]N1CCN(CC1)c2ccccc2 12 1 FRG0000228 | |
| ea85b643fa324a93ea4e2f512edbd8b3 [R]Cc1ccc([R])cc1 7 2 FRG0000229 | |
| 9b1014cfd607f7ab417b0c54794c5d47 [R]c1cccc([R])c1[R] 6 3 FRG0000230 | |
| 1f21ae325dc9a19805a04a8365f25af3 [R]C1CC(=NO1)c2cccc([R])c2[R] 11 3 FRG0000231 | |
| 757bcd8509554edc787cc61a8f48f8e2 [R]c1cccc([R])c1OC 8 2 FRG0000232 | |
| 6c5b6761b1418b55f23fb63e097e1094 [R]c1cccc(OC)c1OC 10 1 FRG0000233 | |
| 33688dfa24816ee1fcdc5c587ef6d3dc [R]C(=O)Nc1cc([R])c([R])c([R])c1 9 4 FRG0000234 | |
| 7e324ed6d41b9bfed72f9fd671b149d3 [R]C(=O)Nc1cc([R])c([R])c(OC)c1 11 3 FRG0000235 | |
| 28ec093bfb4e6f95762af048d84c9dc3 [R]C(=O)Nc1cc([R])c(OC)c([R])c1 11 3 FRG0000236 | |
| f8b56da60e4b054bedbdc980a18a71c6 [R]c1cccc(OC)c1[R] 8 2 FRG0000237 | |
| c76a823c591b9b51389cede68b3da393 [R]c1cc(OC)c(OC)c(OC)c1 12 1 FRG0000238 | |
| 7350f21ba65fe40b955794193beb8384 [R]c1cn([R])nc1C 6 2 FRG0000239 | |
| e284e0eda62c3c5f2c6a757881737622 [R]C1CC(=NO1)c2cn([R])nc2C 11 2 FRG0000240 | |
| 81b4b88363f622f3572a37ce0724413d [R]c1cn(CC)nc1C 8 1 FRG0000241 | |
| 6e7c97f191099b744eb97abc7f380953 [R]c1cccc([R])c1 6 2 FRG0000242 | |
| 7056e805b487e71ef047203a61fd7abe [R]C1CC(=NO1)c2cccc([R])c2 11 2 FRG0000243 | |
| d282a96cf038b2bba34deee88bb1277f [R]C(=O)Nc1ccc(cc1)C(=O)C 12 1 FRG0000244 | |
| 7dc9c6cb16d0c93c71cc979e0d89a7ae [R]c1cccc(OC)c1 8 1 FRG0000245 | |
| 87a640cc527739c842f03cca55c9076f [R]c1cn2ccccc2n1 9 1 FRG0000246 | |
| 74493ffd1a692d594d6ba10eec21bf10 [R]CNC(=O)[R] 4 2 FRG0000247 | |
| e23f07565ac61d49ea14fe575d5bcd06 [R]NC(=O)c1cc([R])c([R])c(OC)c1 11 3 FRG0000248 | |
| 2255c3a8ac83399457ea760be81b39a8 [R]CNC(=O)c1cc([R])c([R])c(OC)c1 12 3 FRG0000249 | |
| bfc7b104a12e7395166e6a06187ad5ee [R]NC(=O)c1cc([R])c(OC)c([R])c1 11 3 FRG0000250 | |
| b42142dcf97feaa4eb8059ef3d49cc4c [R]CNC(=O)c1cc([R])c(OC)c([R])c1 12 3 FRG0000251 | |
| bd4d8e903b2c1fc5352c71d7e393a93d [R]CNC(=O)c1cc([R])c([R])c([R])c1 10 4 FRG0000252 | |
| 9dcff2997593866646749c6010612ccd [R]NC(=O)c1cc([R])c([R])c([R])c1 9 4 FRG0000253 | |
| caca3f65ac9d3c21ad4a3a868959c666 [R]Cc1cn2ccccc2n1 10 1 FRG0000254 | |
| c980d2f3faf5e747a5c98ab1a8ce1ff3 [R]C(=O)Nc1ccc([R])c([R])c1 9 3 FRG0000255 | |
| af445ba483affc598ba443a48bea6575 [R]C(=O)Nc1ccc([R])c(OC)c1 11 2 FRG0000256 | |
| 20170f877b39d307761cea3edc7acfc5 [R]C(=O)Nc1ccc(OC)c([R])c1 11 2 FRG0000257 | |
| 5f9ef1c568c527d4afcaf223bb21c97f [R]C1CC(=NO1)c2ccc(F)cc2 12 1 FRG0000258 | |
| fef83f3fa32653176c70bb96187d0f39 [R]C(=O)Nc1ccc(cc1)C#N 11 1 FRG0000259 | |
| d414ebdd71208f56bc45a80a0a8e3124 [R]c1ccc(cc1)C#N 8 1 FRG0000260 | |
| 0f226bd7d5835e982c9535e9517158c8 [R]c1cc(C)[nH]n1 6 1 FRG0000261 | |
| 577c0c8f931b6e486961db668d5acba6 [R]CSC1=Nc2[nH]ncc2C(=O)N1[R] 12 2 FRG0000262 | |
| d9fec27b9a8f7083e5baec4bc5c09b3b [R]SCC(=O)Nc1cc(C)[nH]n1 11 1 FRG0000263 | |
| 254bde6aca3f85a64b8db791724edc2c [R]C(=O)Nc1cc(C)[nH]n1 9 1 FRG0000264 | |
| ecf6defc926a9f34f0da005f8197a9fe [R]CC(=O)Nc1cc(C)[nH]n1 10 1 FRG0000265 | |
| b1d44544a658e0f84213d92819559ed9 [R]c1ccc(CC)cc1 8 1 FRG0000266 | |
| 798d057b977bba528dfee47da909927b [R]C1CCC(CC1)C(=O)[R] 8 2 FRG0000267 | |
| 8c45a2b47e38b543b14829e96b0d4a05 [R]CC1CCC(CC1)C(=O)[R] 9 2 FRG0000268 | |
| f800a31d76f3adad5c308bf679462019 [R]CCC[R] 3 2 FRG0000269 | |
| 727a15facad903cdffc729e11c1e1840 [R]CCCOC 5 1 FRG0000270 | |
| 20ee8831389e5cc9183462d172043d60 [R]C(=O)NCCCOC 8 1 FRG0000271 | |
| f4b8448d229b3c026b32525454c8efa7 [R]CCCNC(=O)[R] 6 2 FRG0000272 | |
| 6399fad20d12081cf48799f82803c146 [R]Cc1ccc(cc1)C(=O)N[R] 10 2 FRG0000273 | |
| 9644b27ca8bb92adf1f7bed5019cabf7 [R]CCCNC(=O)c1ccc([R])cc1 12 2 FRG0000274 | |
| 3cd0a4a42541970c14751da25e243654 [R]C(=O)NC 4 1 FRG0000275 | |
| f5c23d1f058c1f289dab267649113b64 [R]C1=COCCO1 6 1 FRG0000276 |
This file contains bidirectional Unicode text that may be interpreted or compiled differently than what appears below. To review, open the file in an editor that reveals hidden Unicode characters.
Learn more about bidirectional Unicode characters
| CID Canonical_Smiles InChI InChIKey InChI_AuxInfo | |
| CID0300385 c1ccc(cc1)c2n[nH]c3ccccc23 InChI=1S/C13H10N2/c1-2-6-10(7-3-1)13-11-8-4-5-9-12(11)14-15-13/h1-9H,(H,14,15) MXBKCOLSUUYOHT-UHFFFAOYSA-N AuxInfo=1/1/N:15,13,14,11,12,9,10,7,8,6,3,5,4,1,2/E:(2,3)(6,7)/rA:15NNCCCCCCCCCCCCC/rB:s1;;d-2s3;s1s3;s4;d+3;d+5;d+6;s6;s7;s8d-11;s9;d-10;d-13s14;/rC:4.6783,-1.9359,0;5.2619,-1.1311,0;3.7321,-.6311,0;4.6783,-.3264,0;3.7321,-1.6311,0;4.9889,.6241,0;2.866,-.1311,0;2.866,-2.1311,0;4.3211,1.3684,0;5.9674,.8304,0;2,-.6311,0;2,-1.6311,0;4.6318,2.319,0;6.2781,1.7809,0;5.6103,2.5252,0; | |
| CID0588806 Cc1nc(SCCC(=O)O)c2ccccc2n1 InChI=1S/C12H12N2O2S/c1-8-13-10-5-3-2-4-9(10)12(14-8)17-7-6-11(15)16/h2-5H,6-7H2,1H3,(H,15,16) BWOVZKBKWYSBAR-UHFFFAOYSA-N AuxInfo=1/1/N:16,14,15,10,12,11,9,13,6,7,17,8,4,5,2,3,1/E:(15,16)/rA:17SOONNCCCCCCCCCCCC/rB:;;;;;s4s6;s1d+5s6;s1;d-6;s9;d+7;d-4s5;s10;s12d-14;s13;s2d3s11;/rC:4.5981,.1377,0;2.866,-2.8623,0;2,-1.3623,0;4.5981,3.1377,0;3.7321,1.6377,0;5.4641,1.6377,0;5.4641,2.6377,0;4.5981,1.1377,0;3.7321,-.3623,0;6.358,1.103,0;3.7321,-1.3623,0;6.358,3.1723,0;3.7321,2.6377,0;7.2641,1.6169,0;7.2641,2.6585,0;2.866,3.1377,0;2.866,-1.8623,0; | |
| CID0649913 CCOC(=O)c1ccccc1NC(=O)CSc2ncc(C(=O)OCC)c(N)n2 InChI=1S/C18H20N4O5S/c1-3-26-16(24)11-7-5-6-8-13(11)21-14(23)10-28-18-20-9-12(15(19)22-18)17(25)27-4-2/h5-9H,3-4,10H2,1-2H3,(H,21,23)(H2,19,20,22) CRPXWMYEKXYXIE-UHFFFAOYSA-N AuxInfo=1/1/N:27,28,23,26,17,15,14,13,24,18,12,20,11,16,22,19,25,21,10,9,7,8,4,5,6,2,3,1/rA:28SOOOOONNNNCCCCCCCCCCCCCCCCCC/rB:;;;;;;;;;s7;s11;d+11;d-12;s13;d4s7;s14d-15;s1s16;s2d5s12;;s1s8d+9;d+8s10s20;s2;s9d-20;s3d6s20;s3;s23;s26;/rC:6.3301,-1.5,0;11.5263,.5,0;2.866,1.5,0;8.0622,-2.5,0;9.7942,.5,0;2,0,0;8.9282,-1,0;4.5981,-1.5,0;5.4641,0,0;2.866,-1.5,0;9.7942,-1.5,0;10.6603,-1,0;9.7942,-2.5,0;11.5263,-1.5,0;10.6603,-3,0;8.0622,-1.5,0;11.5263,-2.5,0;7.1962,-1,0;10.6603,0,0;3.7321,0,0;5.4641,-1,0;3.7321,-1,0;11.5263,1.5,0;4.5981,.5,0;2.866,.5,0;2,2,0;12.3923,2,0;2,3,0; | |
| CID0651058 COC(=O)c1ccccc1NC(=O)CN2CCC(CC2)NC(=O)c3ccccc3C InChI=1S/C23H27N3O4/c1-16-7-3-4-8-18(16)22(28)24-17-11-13-26(14-12-17)15-21(27)25-20-10-6-5-9-19(20)23(29)30-2/h3-10,17H,11-15H2,1-2H3,(H,24,28)(H,25,27) OEANPIFWBBTVJJ-UHFFFAOYSA-N AuxInfo=1/1/N:21,30,24,22,28,27,20,18,26,25,9,10,11,12,13,17,8,16,23,19,15,14,29,6,7,5,2,1,4,3/E:(11,12)(13,14)/rA:30OOOONNNCCCCCCCCCCCCCCCCCCCCCCC/rB:;;;;;;s6;s8;s8;s5s9;s5s10;s5;d1s6;d2s7s13;s14;s16;d+16;s7;d-17;s17;s18;s19;s20d-22;d+19;d-23;s25;s26d-27;s3d4s23;s3;/rC:8.9282,3.25,0;7.1962,-1.75,0;2.866,-3.25,0;3.7321,-1.75,0;7.1962,.25,0;9.7942,1.75,0;5.4641,-1.75,0;8.9282,1.25,0;8.0622,1.75,0;8.9282,.25,0;7.1962,1.25,0;8.0622,-.25,0;6.3301,-.25,0;9.7942,2.75,0;6.3301,-1.25,0;10.6603,3.25,0;11.5263,2.75,0;10.6603,4.25,0;5.4641,-2.75,0;12.3923,3.25,0;11.5263,1.75,0;11.5263,4.75,0;4.5981,-3.25,0;12.3923,4.25,0;6.3301,-3.25,0;4.5981,-4.25,0;6.3301,-4.25,0;5.4641,-4.75,0;3.7321,-2.75,0;2,-2.75,0; | |
| CID0651323 COC(=O)c1ccccc1NC(=O)CN2CCC(CC2)NC(=O)c3ccc(C)cc3 InChI=1S/C23H27N3O4/c1-16-7-9-17(10-8-16)22(28)24-18-11-13-26(14-12-18)15-21(27)25-20-6-4-3-5-19(20)23(29)30-2/h3-10,18H,11-15H2,1-2H3,(H,24,28)(H,25,27) CYSCIEFIGJZUKN-UHFFFAOYSA-N AuxInfo=1/1/N:27,30,28,26,25,24,20,21,18,19,9,10,11,12,13,23,16,8,22,17,14,15,29,6,7,5,1,2,4,3/E:(7,8)(9,10)(11,12)(13,14)/rA:30OOOONNNCCCCCCCCCCCCCCCCCCCCCCC/rB:;;;;;;s6;s8;s8;s5s9;s5s10;s5;d1s7s13;d2s6;s15;s7;d+16;s16;s18;d-19;s17;d-20s21;d+17;d-22;s24;s23;s25d-26;s3d4s22;s3;/rC:7.1962,-1.75,0;8.9282,3.25,0;2.866,-3.25,0;3.7321,-1.75,0;7.1962,.25,0;9.7942,1.75,0;5.4641,-1.75,0;8.9282,1.25,0;8.0622,1.75,0;8.9282,.25,0;7.1962,1.25,0;8.0622,-.25,0;6.3301,-.25,0;6.3301,-1.25,0;9.7942,2.75,0;10.6603,3.25,0;5.4641,-2.75,0;11.5263,2.75,0;10.6603,4.25,0;12.3923,3.25,0;11.5263,4.75,0;4.5981,-3.25,0;12.3923,4.25,0;6.3301,-3.25,0;4.5981,-4.25,0;6.3301,-4.25,0;13.2583,4.75,0;5.4641,-4.75,0;3.7321,-2.75,0;2,-2.75,0; | |
| CID0658703 N#Cc1c(NCc2ccccc2)ccnc1NCc3cccnc3 InChI=1S/C19H17N5/c20-11-17-18(23-13-15-5-2-1-3-6-15)8-10-22-19(17)24-14-16-7-4-9-21-12-16/h1-10,12H,13-14H2,(H2,22,23,24) ZDVBOUMTYMSOFM-UHFFFAOYSA-N AuxInfo=1/1/N:21,18,19,23,14,15,17,13,24,16,22,20,6,11,10,12,9,7,8,5,4,3,1,2/E:(2,3)(5,6)/rA:24NNNNNCCCCCCCCCCCCCCCCCCC/rB:;;;;s1;s1;s2d+3;d+7s8;s6;s2;s11;s7;d+10;s10;s3d-13;s12;s14;d-15;s4d+12;d-18s19;t5s9;d-17;d-4s23;/rC:5.4641,0,0;8.9282,0,0;8.0622,-1.5,0;12.3923,0,0;7.1962,2,0;4.5981,-.5,0;6.3301,-.5,0;8.0622,-.5,0;7.1962,0,0;3.7321,0,0;9.7942,-.5,0;10.6603,0,0;6.3301,-1.5,0;2.866,-.5,0;3.7321,1,0;7.1962,-2,0;10.6603,1,0;2,0,0;2.866,1.5,0;11.5263,-.5,0;2,1,0;7.1962,1,0;11.5263,1.5,0;12.3923,1,0; | |
| CID0658795 COc1ccc(CN\C(=C(\C#N)/C(=O)N)\C)cc1OC InChI=1S/C14H17N3O3/c1-9(11(7-15)14(16)18)17-8-10-4-5-12(19-2)13(6-10)20-3/h4-6,17H,8H2,1-3H3,(H2,16,18)/b11-9- WDXWUJDVGIHLTH-LUAWRHEFSA-N AuxInfo=1/1/N:15,19,18,10,13,9,20,8,14,7,16,12,11,17,6,5,4,3,2,1/rA:20OOONNNCCCCCCCCCCCCCC/rB:;;;;;;s4s7;d+7;s7;s1s9;s2d-11;d-10s12;s4;s14;d-14;d3s5s16;s1;s2;t6s16;/rC:4.5981,3.405,0;2.866,2.405,0;5.4641,-2.095,0;6.3301,-.595,0;6.3301,-3.595,0;8.9282,-3.095,0;5.4641,.905,0;6.3301,.405,0;5.4641,1.905,0;4.5981,.405,0;4.5981,2.405,0;3.7321,1.905,0;3.7321,.905,0;7.1962,-1.095,0;8.0622,-.595,0;7.1962,-2.095,0;6.3301,-2.595,0;5.4641,3.905,0;2,1.905,0;8.0622,-2.595,0; | |
| CID0660128 COC(=O)C1=CN(Cc2ccc3OCOc3c2)C(=O)C(=C1)Br InChI=1S/C15H12BrNO5/c1-20-15(19)10-5-11(16)14(18)17(7-10)6-9-2-3-12-13(4-9)22-8-21-12/h2-5,7H,6,8H2,1H3 JPCKTZROQCNHJX-UHFFFAOYSA-N AuxInfo=1/0/N:22,13,14,10,20,8,15,18,9,17,19,12,11,16,21,1,7,4,6,5,3,2/rA:22BrOOOOONCCCCCCCCCCCCCCC/rB:;;;;;;s7;s8;d+9;s2s10;s3d-11;s9;s12d-13;s7;d4s7;d-15;s2s3;s1s16;s17d+19;s5d6s17;s5;/rC:2,1.75,0;9.0084,1.5547,0;9.0084,-.0547,0;3.7321,2.75,0;2.866,-1.75,0;4.5981,-1.75,0;4.5981,1.25,0;5.4641,1.75,0;6.3301,1.25,0;7.1962,1.75,0;8.0622,1.25,0;8.0622,.25,0;6.3301,.25,0;7.1962,-.25,0;4.5981,.25,0;3.7321,1.75,0;3.7321,-.25,0;9.592,.75,0;2.866,1.25,0;2.866,.25,0;3.7321,-1.25,0;2.866,-2.75,0; | |
| CID0661045 COC(=O)C1=CN(Cc2ccc(OC)c(OC)c2)C(=O)C(=C1)Br InChI=1S/C16H16BrNO5/c1-21-13-5-4-10(6-14(13)22-2)8-18-9-11(16(20)23-3)7-12(17)15(18)19/h4-7,9H,8H2,1-3H3 KYPSKTLCRCBHDD-UHFFFAOYSA-N AuxInfo=1/0/N:22,21,23,12,17,10,19,8,11,9,15,18,16,14,13,20,1,7,4,6,3,2,5/rA:23BrOOOOONCCCCCCCCCCCCCCCC/rB:;;;;;;s7;s8;d+9;s7;s9;d4s7;s2s10;d-11;s3d-14;d-12s16;s1s13;s15d+18;s5d6s15;s2;s3;s5;/rC:2,2.5,0;5.4641,-3.5,0;7.1962,-2.5,0;2,.5,0;5.4641,3.5,0;6.3301,2,0;3.7321,.5,0;3.7321,-.5,0;4.5981,-1,0;4.5981,-2,0;4.5981,1,0;5.4641,-.5,0;2.866,1,0;5.4641,-2.5,0;4.5981,2,0;6.3301,-2,0;6.3301,-1,0;2.866,2,0;3.7321,2.5,0;5.4641,2.5,0;4.5981,-4,0;8.0622,-2,0;6.3301,4,0; | |
| CID0661441 CC(Sc1ccc2ccccc2n1)C(=O)O InChI=1S/C12H11NO2S/c1-8(12(14)15)16-11-7-6-9-4-2-3-5-10(9)13-11/h2-8H,1H3,(H,14,15) JLYPYACZXPBHLU-UHFFFAOYSA-N AuxInfo=1/1/N:13,14,15,11,12,9,10,7,5,6,8,16,4,2,3,1/E:(14,15)/rA:16SOONCCCCCCCCCCCC/rB:;;;;s4s5;s1;s1d+4;s5;s8d-9;d-5;d+6;s7;s11;s12d-14;s2d3s7;/rC:5.135,-.5173,0;2.5369,-.0173,0;3.403,-1.5173,0;6.8671,-.5173,0;7.7331,.9827,0;7.7331,-.0173,0;4.269,-.0173,0;6.001,-.0173,0;6.8671,1.4827,0;6.001,.9827,0;8.627,1.5173,0;8.627,-.552,0;4.269,.9827,0;9.5331,1.0035,0;9.5331,-.0381,0;3.403,-.5173,0; | |
| CID0793991 CCCN1C=CC(=C2C(=O)c3ccccc3C2=O)C=C1 InChI=1S/C17H15NO2/c1-2-9-18-10-7-12(8-11-18)15-16(19)13-5-3-4-6-14(13)17(15)20/h3-8,10-11H,2,9H2,1H3 KRJAEYDFBGVIJB-UHFFFAOYSA-N AuxInfo=1/0/N:18,11,19,20,16,17,12,13,6,14,15,5,7,8,4,9,10,3,1,2/E:(3,4)(5,6)(7,8)(10,11)(13,14)(16,17)(19,20)/rA:20OONCCCCCCCCCCCCCCCCC/rB:;;;d4;s3;;s7;d1s4s7;d2s4s8;s6;s5;s5;s3d-12;s3d-13;d-7;d-8;s11;s16;s17d-19;/rC:4.9889,1.7553,0;4.9889,-1.7553,0;8.2619,0,0;5.2619,0,0;6.2619,0,0;9.2619,0,0;3.7321,.5,0;3.7321,-.5,0;4.6783,.8047,0;4.6783,-.8047,0;9.7619,-.866,0;6.7619,.866,0;6.7619,-.866,0;7.7619,.866,0;7.7619,-.866,0;2.866,1,0;2.866,-1,0;10.7619,-.866,0;2,.5,0;2,-.5,0; | |
| CID0796100 Fc1cccc(Nc2cc(ncn2)n3cccn3)c1 InChI=1S/C13H10FN5/c14-10-3-1-4-11(7-10)18-12-8-13(16-9-15-12)19-6-2-5-17-19/h1-9H,(H,15,16,18) BIKLNZVXIPYGJC-UHFFFAOYSA-N AuxInfo=1/1/N:15,16,17,12,19,13,11,10,18,14,9,8,7,1,5,4,6,3,2/rA:19FNNNNNCCCCCCCCCCCCC/rB:;;;;s2;s2d+4;s3s5;s3;s7d+8;d+9;s9;s2;s1s11;d-12;d-13;d+14s15;s4d-5;d-6s16;/rC:8.7788,1.1012,0;3.5827,-1.8988,0;5.3147,1.1012,0;5.3147,-1.8988,0;6.1808,-.3988,0;3.4781,-2.8933,0;4.4487,-1.3988,0;5.3147,.1012,0;6.1808,1.6012,0;4.4487,-.3988,0;7.0468,1.1012,0;6.1808,2.6012,0;2.6691,-1.492,0;7.9128,1.6012,0;7.0468,3.1012,0;2,-2.2352,0;7.9128,2.6012,0;6.1808,-1.3988,0;2.5,-3.1012,0; | |
| CID0979869 CCN1CCN(CC1)c2c(Cl)cccc2NC(=O)c3oc(Br)cc3 InChI=1S/C17H19BrClN3O2/c1-2-21-8-10-22(11-9-21)16-12(19)4-3-5-13(16)20-17(23)14-6-7-15(18)24-14/h3-7H,2,8-11H2,1H3,(H,20,23) PRHPUPZVWXCHHI-UHFFFAOYSA-N AuxInfo=1/1/N:15,12,19,18,17,22,23,8,9,10,11,16,14,21,24,13,20,1,2,7,5,6,4,3/E:(8,9)(10,11)/rA:24BrClOONNNCCCCCCCCCCCCCCCCC/rB:;;;;;;s5;s5;s6s8;s6s9;s5;s6;s7d-13;s12;s2s13;s14;d+16;d-17s18;d4s7;s3s20;d-21;s22;s1s3d+23;/rC:2,-1.0181,0;9.7734,-1.25,0;3.6637,-1.6567,0;5.4432,-2.75,0;8.0413,1.75,0;8.0413,-.25,0;6.3092,-1.25,0;7.1753,1.25,0;8.9073,1.25,0;7.1753,.25,0;8.9073,.25,0;8.0413,2.75,0;8.0413,-1.25,0;7.1753,-1.75,0;8.9073,3.25,0;8.9073,-1.75,0;7.1753,-2.75,0;8.9073,-2.75,0;8.0413,-3.25,0;5.4432,-1.75,0;4.5772,-1.25,0;4.4727,-.2555,0;3.4945,-.0476,0;2.9945,-.9136,0; | |
| CID1045996 CCOc1ccc(CC(=O)Nc2c(oc3ccccc23)C(=O)N)cc1OCC InChI=1S/C21H22N2O5/c1-3-26-16-10-9-13(11-17(16)27-4-2)12-18(24)23-19-14-7-5-6-8-15(14)28-20(19)21(22)25/h5-11H,3-4,12H2,1-2H3,(H2,22,25)(H,23,24) ARRPMFYEKBZOMJ-UHFFFAOYSA-N AuxInfo=1/1/N:28,27,26,25,22,23,16,20,18,21,15,10,11,9,12,19,17,14,8,13,24,7,6,4,5,3,2,1/rA:28OOOOONNCCCCCCCCCCCCCCCCCCCCC/rB:;;;;;;s6;s8;;s10;s1s9;s1d+8;d4s6s10;d+11;d+9;s2s15;s11;s3d-17;d+12;d-18s19;s16;s20d-22;d5s7s13;s2;s3;s25;s26;/rC:6.9856,-4.1643,0;3.6463,1.1667,0;4.2677,3.0677,0;5.6499,-1.0662,0;9.0692,-2.4935,0;7.2962,-1.6043,0;9.0692,-4.2256,0;6.9856,-2.5548,0;6.0393,-2.8596,0;6.939,.0905,0;6.2712,.8348,0;6.0393,-3.8596,0;7.5692,-3.3596,0;6.6284,-.86,0;5.2927,.6286,0;5.1733,-2.3596,0;4.6249,1.3729,0;6.5819,1.7853,0;4.9355,2.3234,0;5.1733,-4.3596,0;5.914,2.5296,0;4.3073,-2.8596,0;4.3073,-3.8596,0;8.5692,-3.3596,0;2.9785,1.911,0;4.5783,4.0182,0;2,1.7048,0;3.9105,4.7625,0; | |
| CID1087003 CN1C(=O)N(C)c2c(C1=O)c(c3ccccc3)n4c5ccccc5ncc24 InChI=1S/C21H16N4O2/c1-23-19-16-12-22-14-10-6-7-11-15(14)25(16)18(13-8-4-3-5-9-13)17(19)20(26)24(2)21(23)27/h3-12H,1-2H3 YVZVATKCIBNZNI-UHFFFAOYSA-N AuxInfo=1/0/N:17,21,27,25,26,24,23,19,20,22,18,14,13,16,11,10,8,9,7,12,15,6,4,5,3,1,2/E:(4,5)(8,9)/rA:27OONNNNCCCCCCCCCCCCCCCCCCCCC/rB:;;;;;s4;s7;s3d-8;s3d+7;s3;d1s5s8;s9;d-6s10;d2s4s5;s6s11;s4;d+11;d+13;s13;s5;d+16;s18;s22d-23;s19;d-20;d-25s26;/rC:3.3794,-.7305,0;2.6294,2.718,0;6.2952,.4533,0;4.3106,2.1812,0;2.9772,.9878,0;7.6335,1.9396,0;4.9922,1.4017,0;4.6858,.4561,0;5.4895,-.1289,0;5.9862,1.4043,0;7.2734,.2454,0;3.6766,.2243,0;5.4878,-1.1289,0;6.6554,2.1475,0;3.2963,1.9729,0;7.9425,.9885,0;4.6297,3.1289,0;7.58,-.7501,0;6.3529,-1.6304,0;4.6209,-1.6274,0;2,.7753,0;8.9646,.7877,0;8.5971,-.9746,0;9.2941,-.2005,0;6.3512,-2.6304,0;4.6192,-2.6274,0;5.4843,-3.1289,0; | |
| CID1245872 NC(=O)c1cc(Cc2ccccc2)sc1NC(=O)c3occc3 InChI=1S/C17H14N2O3S/c18-15(20)13-10-12(9-11-5-2-1-3-6-11)23-17(13)19-16(21)14-7-4-8-22-14/h1-8,10H,9H2,(H2,18,20)(H,19,21) CHERUBJRJGWGFE-UHFFFAOYSA-N AuxInfo=1/1/N:19,17,18,22,13,14,21,23,7,11,9,8,10,20,15,16,12,6,5,3,4,2,1/E:(2,3)(5,6)/rA:23SOOONNCCCCCCCCCCCCCCCCC/rB:;;;;;;s1s7;s7;;d-8s10;s1s5d-10;d+9;s9;d3s6s10;d4s5;s13;d-14;d-17s18;s2s16;d-20;s21;s2d-22;/rC:3.8366,.0207,0;4.5404,3.7307,0;6.897,.067,0;3.6392,1.8466,0;5.2215,1.1421,0;6.716,-1.6555,0;2.866,-1.4739,0;3.7321,-.9739,0;2.866,-2.4739,0;5.3147,-.6374,0;4.6456,-1.3806,0;4.8147,.2286,0;3.7321,-2.9739,0;2,-2.9739,0;6.3092,-.742,0;4.6337,1.9511,0;3.7321,-3.9739,0;2,-3.9739,0;2.866,-4.4739,0;5.0404,2.8647,0;6.0186,3.0726,0;6.1231,4.0671,0;5.2095,4.4739,0; | |
| CID1288597 Cc1nc(CSC2=Nc3[nH]ncc3C(=O)N2c4ccccc4)cs1 InChI=1S/C16H13N5OS2/c1-10-18-11(8-23-10)9-24-16-19-14-13(7-17-20-14)15(22)21(16)12-5-3-2-4-6-12/h2-8H,9H2,1H3,(H,17,20) PJYACDWZSICXPQ-UHFFFAOYSA-N AuxInfo=1/1/N:24,21,19,20,16,17,15,22,14,23,18,12,9,13,11,10,7,8,5,6,4,3,2,1/E:(3,4)(5,6)/rA:24SSONNNNNCCCCCCCCCCCCCCCC/rB:;;;;;s6;;;s1s4d+5;d3s4s9;s4;s5s6d-9;s1;d-7s9;d+12;s12;s8s14;s16;d-17;d-19s20;s2d-18;s2d-8;s23;/rC:5.4432,-.3988,0;3.4945,-3.1012,0;7.1753,2.6012,0;6.3092,1.1012,0;7.1753,-.3988,0;8.9875,-.2035,0;9.5711,.6012,0;3.6637,-1.492,0;8.0413,1.1012,0;6.3092,.1012,0;7.1753,1.6012,0;5.4432,1.6012,0;8.0413,.1012,0;5.4432,-1.3988,0;8.9875,1.4059,0;4.5772,1.1012,0;5.4432,2.6012,0;4.5772,-1.8988,0;3.7112,1.6012,0;4.5772,3.1012,0;3.7112,2.6012,0;4.4727,-2.8933,0;2.9945,-2.2352,0;2,-2.1307,0; | |
| CID1294440 Brc1oc(cc1)C(=O)Nc2ccccc2N3CCOCC3 InChI=1S/C15H15BrN2O3/c16-14-6-5-13(21-14)15(19)17-11-3-1-2-4-12(11)18-7-9-20-10-8-18/h1-6H,7-10H2,(H,17,19) CLXUHLBNKWJORM-UHFFFAOYSA-N AuxInfo=1/1/N:16,15,14,13,19,20,7,8,9,10,12,11,18,21,17,1,6,5,4,2,3/E:(7,8)(9,10)/rA:21BrOOONNCCCCCCCCCCCCCCC/rB:;;;;;s5;s5;s2s7;s2s8;s5;s6s11;d+11;d+12;s13;s14d-15;d4s6;s3s17;d-18;s19;s1s3d+20;/rC:5.2423,3.4239,0;2,-.4239,0;5.5211,1.6639,0;7.1962,-.4239,0;3.7321,-1.4239,0;5.4641,-.4239,0;2.866,-1.9239,0;3.7321,-.4239,0;2,-1.4239,0;2.866,.0761,0;4.5981,-1.9239,0;5.4641,-1.4239,0;4.5981,-2.9239,0;6.3301,-1.9239,0;5.4641,-3.4239,0;6.3301,-2.9239,0;6.3301,.0761,0;6.3301,1.0761,0;7.1391,1.6639,0;6.8301,2.6149,0;5.8301,2.6149,0; | |
| CID2091134 COc1cc(CC(=O)Nc2sccc2C(=O)N)cc(OC)c1OC InChI=1S/C16H18N2O5S/c1-21-11-6-9(7-12(22-2)14(11)23-3)8-13(19)18-16-10(15(17)20)4-5-24-16/h4-7H,8H2,1-3H3,(H2,17,20)(H,18,19) XRYHWBQNTJUJLS-UHFFFAOYSA-N AuxInfo=1/1/N:22,23,24,19,20,12,11,10,9,18,13,14,16,15,21,17,8,7,5,6,2,3,4,1/E:(1,2)(6,7)(11,12)(21,22)/rA:24SOOOOONNCCCCCCCCCCCCCCCC/rB:;;;;;;;;s9;d+9;s9;s2d+12;s3s11;s4s13d-14;d5s7s10;s1s7;d-17;s18;s1d-19;d6s8s18;s2;s3;s4;/rC:2.6691,-1.3149,0;7.0468,3.2783,0;3.5827,3.2783,0;5.3147,4.2783,0;3.5827,.2783,0;5.1723,-3.0763,0;4.4487,-1.2217,0;4.0134,-4.3635,0;5.3147,1.2783,0;5.3147,.2783,0;4.4487,1.7783,0;6.1808,1.7783,0;6.1808,2.7783,0;4.4487,2.7783,0;5.3147,3.2783,0;4.4487,-.2217,0;3.5827,-1.7217,0;3.4781,-2.7162,0;2.5,-2.9241,0;2,-2.0581,0;4.2213,-3.3853,0;7.9128,2.7783,0;2.7167,2.7783,0;6.1808,4.7783,0; | |
| CID2099071 CCN(CC)S(=O)(=O)c1ccc2nc(COC(=O)c3n[nH]c4ccccc34)[nH]c2c1 InChI=1S/C20H21N5O4S/c1-3-25(4-2)30(27,28)13-9-10-16-17(11-13)22-18(21-16)12-29-20(26)19-14-7-5-6-8-15(14)23-24-19/h5-11H,3-4,12H2,1-2H3,(H,21,22)(H,23,24) IDBUYBIWHUUWRC-UHFFFAOYSA-N AuxInfo=1/1/N:20,21,12,13,29,30,27,28,17,18,15,22,11,23,25,16,14,19,24,26,8,7,9,10,6,5,2,3,4,1/E:(1,2)(3,4)(27,28)/CRV:30.6/rA:30SOOOONNNNNCCCCCCCCCCCCCCCCCCCC/rB:d1;d1;;;s1;;;;s9;s1;s6;s6;s7;d+11s14;s8d-14;s11;s16d-17;s7d-8;s12;s13;s4s19;;d-10s23;s9s23;s4d5s24;d+23;d+25;s27;s28d-29;/rC:4.5981,1.4616,0;5.0981,2.3277,0;4.0981,.5956,0;10.226,-.4044,0;11.726,.4616,0;3.7321,1.9616,0;8.1424,1.2664,0;8.1424,-.3431,0;12.0579,-2.8453,0;11.3209,-2.1782,0;5.4641,.9616,0;2.866,1.4616,0;3.7321,2.9616,0;7.1962,.9616,0;6.3301,1.4616,0;7.1962,-.0384,0;5.4641,-.0384,0;6.3301,-.5384,0;8.726,.4616,0;2,1.9616,0;2.866,3.4616,0;9.726,.4616,0;12.7147,-1.3735,0;11.726,-1.2704,0;12.9209,-2.352,0;11.226,-.4044,0;13.459,-.7056,0;13.8714,-2.6626,0;14.4095,-1.0163,0;14.6157,-1.9948,0; | |
| CID2377706 O=C(COC(=O)c1n[nH]c2ccccc12)Nc3ccc(cc3)S(=O)(=O)N4CCCC4 InChI=1S/C20H20N4O5S/c25-18(13-29-20(26)19-16-5-1-2-6-17(16)22-23-19)21-14-7-9-15(10-8-14)30(27,28)24-11-3-4-12-24/h1-2,5-10H,3-4,11-13H2,(H,21,25)(H,22,23) MFFBAVUXCAMGJT-UHFFFAOYSA-N AuxInfo=1/1/N:29,30,13,14,26,27,18,19,16,17,11,12,25,20,15,21,23,22,24,28,8,9,10,7,5,6,2,3,4,1/E:(3,4)(7,8)(9,10)(11,12)(27,28)/CRV:30.6/rA:30SOOOOONNNNCCCCCCCCCCCCCCCCCCCC/rB:d1;d1;;;;s1;;;s9;s7;s7;s11;s12s13;s1;d+15;s15;s16;d-17;s8d+18s19;;d5s8;s9s21;d-10s21;s4s22;d-21;d+23;s4d6s24;s26;s27d-29;/rC:11.4813,2.5843,0;11.2751,3.5628,0;11.6875,1.6058,0;5.9674,-.3478,0;7.9245,.0646,0;4.3211,.1902,0;12.4598,2.7905,0;7.5673,1.7594,0;4.6783,-3.114,0;5.2619,-2.3093,0;13.2018,2.1201,0;12.8681,3.7034,0;14.0687,2.6186,0;13.8625,3.5971,0;10.5028,2.3781,0;9.8349,3.1224,0;10.1921,1.4276,0;8.8564,2.9162,0;9.2136,1.2213,0;8.5458,1.9656,0;3.7321,-1.8093,0;7.2566,.8089,0;3.7321,-2.8093,0;4.6783,-1.5046,0;6.2781,.6027,0;2.866,-1.3093,0;2.866,-3.3093,0;4.9889,-.5541,0;2,-1.8093,0;2,-2.8093,0; | |
| CID2501747 NC(=O)c1ccsc1NC(=O)c2ccc(cc2)S(=O)(=O)N3CCCCC3 InChI=1S/C17H19N3O4S2/c18-15(21)14-8-11-25-17(14)19-16(22)12-4-6-13(7-5-12)26(23,24)20-9-2-1-3-10-20/h4-8,11H,1-3,9-10H2,(H2,18,21)(H,19,22) QCMGFWVZIVDQKD-UHFFFAOYSA-N AuxInfo=1/1/N:14,12,13,18,19,16,17,24,10,11,25,20,15,23,26,21,22,9,8,7,6,5,3,4,2,1/E:(2,3)(4,5)(6,7)(9,10)(23,24)/CRV:26.6/rA:26SSOOOONNNCCCCCCCCCCCCCCCCC/rB:;d1;d1;;;s1;;;s7;s7;s10;s11;s12s13;s1;d+15;s15;s16;d-17;d-18s19;d5s8s20;s2s8;d-22;s23;s2d-24;d6s9s23;/rC:5.9589,2.0272,0;5.9019,-4.0606,0;4.9589,2.0272,0;6.9589,2.0272,0;6.8249,-2.4728,0;3.1249,-2.7734,0;5.9589,3.0272,0;5.0929,-2.4728,0;2.5897,-4.4207,0;5.0929,3.5272,0;6.8249,3.5272,0;5.0929,4.5272,0;6.8249,4.5272,0;5.9589,5.0272,0;5.9589,1.0272,0;5.0929,.5272,0;6.8249,.5272,0;5.0929,-.4728,0;6.8249,-.4728,0;5.9589,-.9728,0;5.9589,-1.9728,0;5.0929,-3.4728,0;4.2839,-4.0606,0;4.5929,-5.0117,0;5.5929,-5.0117,0;3.3328,-3.7516,0; | |
| CID2575371 NC(=O)c1ccsc1NC(=O)CSC2=Nc3ccccc3C(=O)N2CCCO InChI=1S/C18H18N4O4S2/c19-15(25)12-6-9-27-16(12)21-14(24)10-28-18-20-13-5-2-1-4-11(13)17(26)22(18)7-3-8-23/h1-2,4-6,9,23H,3,7-8,10H2,(H2,19,25)(H,21,24) XIDZPFUUHWAPJO-UHFFFAOYSA-N AuxInfo=1/1/N:21,22,12,18,19,26,11,17,27,20,14,25,16,23,28,24,13,15,10,8,9,7,4,5,6,3,2,1/rA:28SSOOOONNNNCCCCCCCCCCCCCCCCCC/rB:;;;;;;;;;s7;s11;d3s7;s13;s1s7d+8;s8s14;s4s12;d+14;d+16;s1;s18;s19d-21;d5s9s20;s2s9;d-24;s25;s2d-26;d6s10s25;/rC:5.3147,-.6233,0;2.6691,1.9699,0;7.0468,-3.6233,0;4.4487,-5.1233,0;3.5827,.3767,0;5.1723,3.7313,0;6.1808,-2.1233,0;7.0468,-.6233,0;4.4487,1.8767,0;4.0134,5.0185,0;5.3147,-2.6233,0;5.3147,-3.6233,0;7.0468,-2.6233,0;7.9128,-2.1233,0;6.1808,-1.1233,0;7.9128,-1.1233,0;4.4487,-4.1233,0;8.8067,-2.658,0;8.8067,-.5887,0;5.3147,.3767,0;9.7128,-2.1441,0;9.7128,-1.1025,0;4.4487,.8767,0;3.5827,2.3767,0;3.4781,3.3712,0;2.5,3.5791,0;2,2.7131,0;4.2213,4.0403,0; | |
| CID2589475 Cc1sc2N=C(SCC(=O)Nc3sccc3C(=O)N)N(CC=C)C(=O)c2c1C InChI=1S/C18H18N4O3S3/c1-4-6-22-17(25)13-9(2)10(3)28-16(13)21-18(22)27-8-12(23)20-15-11(14(19)24)5-7-26-15/h4-5,7H,1,6,8H2,2-3H3,(H2,19,24)(H,20,23) FUZIWPKANNHWFY-UHFFFAOYSA-N AuxInfo=1/1/N:25,18,19,21,26,17,27,20,12,15,24,22,11,28,23,13,14,16,10,9,8,7,5,6,4,3,2,1/rA:28SSSOOONNNNCCCCCCCCCCCCCCCCCC/rB:;;;;;;;;;;s11;s1s8d-11;d4s7s11;s1d-12;s2s7d+8;s7;s12;s15;s2;s17;d5s9s20;s3s9;d-23;d21;s24;s3d-26;d6s10s24;/rC:8.859,1.7236,0;5.3147,1.5283,0;2.6691,-1.0649,0;7.0468,4.5283,0;3.5827,.5283,0;5.1723,-2.8263,0;6.1808,3.0283,0;7.0468,1.5283,0;4.4487,-.9717,0;4.0134,-4.1135,0;7.9128,3.0283,0;8.859,3.3331,0;7.9128,2.0283,0;7.0468,3.5283,0;9.4426,2.5283,0;6.1808,2.0283,0;5.3147,3.5283,0;9.1697,4.2836,0;10.4426,2.5283,0;5.3147,.5283,0;4.4487,3.0283,0;4.4487,.0283,0;3.5827,-1.4717,0;3.4781,-2.4662,0;3.5827,3.5283,0;2.5,-2.6741,0;2,-1.8081,0;4.2213,-3.1353,0; | |
| CID2953401 COCCNC(=O)C1CCC(CN2C(=S)Nc3ccccc3C2=O)CC1 InChI=1S/C19H25N3O3S/c1-25-11-10-20-17(23)14-8-6-13(7-9-14)12-22-18(24)15-4-2-3-5-16(15)21-19(22)26/h2-5,13-14H,6-12H2,1H3,(H,20,23)(H,21,26) KFXLQROCBSAZFL-UHFFFAOYSA-N AuxInfo=1/1/N:26,24,25,22,23,10,11,12,13,19,21,14,8,9,18,20,15,16,17,6,7,5,2,3,4,1/E:(6,7)(8,9)/rA:26SOOONNNCCCCCCCCCCCCCCCCCCC/rB:;;;;;;;;s8;s8;s9s10;s9s11;s5s8;d2s6s9;d3s5;d1s5s7;s16;s6;s7s18;s4s19;d+18;d+20;s22;s23d-24;s4;/rC:9.7942,1,0;6.3301,2,0;11.5263,-2,0;2.866,1,0;10.6603,-.5,0;5.4641,.5,0;11.5263,1,0;8.9282,-.5,0;7.1962,.5,0;8.9282,.5,0;8.0622,-1,0;8.0622,1,0;7.1962,-.5,0;9.7942,-1,0;6.3301,1,0;11.5263,-1,0;10.6603,.5,0;12.3923,-.5,0;4.5981,1,0;12.3923,.5,0;3.7321,.5,0;13.2862,-1.0347,0;13.2862,1.0347,0;14.1923,-.5208,0;14.1923,.5208,0;2,.5,0; | |
| CID2962251 CCCn1cc(NC(=O)C2CC(=NO2)c3cccc(Br)c3)cn1 InChI=1S/C16H17BrN4O2/c1-2-6-21-10-13(9-18-21)19-16(22)15-8-14(20-23-15)11-4-3-5-12(17)7-11/h3-5,7,9-10,15H,2,6,8H2,1H3,(H,19,22) LEPBIJKMMZXYCE-UHFFFAOYSA-N AuxInfo=1/1/N:20,15,22,19,23,13,18,9,17,16,12,21,14,10,8,11,1,7,5,6,4,3,2/rA:23BrOONNNNCCCCCCCCCCCCCCCC/rB:;;;;s2;s4;s2;s8;d-6s9;d3s5s8;s10;s4;s5;s13;s4d+14;d-7s14;d+12;s12;s15;s1s18;d-19;d+21s22;/rC:2.9028,-5.5546,0;5.1349,-1.0158,0;2.5526,-.3113,0;2.866,3.0546,0;3.9538,.7068,0;5.4439,-1.9669,0;2.057,2.4669,0;4.1349,-1.0158,0;3.8258,-1.9669,0;4.6349,-2.5546,0;3.5471,-.2068,0;4.6349,-3.5546,0;2.866,4.0546,0;3.366,1.5158,0;2,4.5546,0;3.675,2.4669,0;2.366,1.5158,0;3.7688,-4.0546,0;5.5009,-4.0546,0;2,5.5546,0;3.7688,-5.0546,0;5.5009,-5.0546,0;4.6349,-5.5546,0; | |
| CID2971411 NC(=O)c1ccsc1NC(=O)c2cccs2 InChI=1S/C10H8N2O2S2/c11-8(13)6-3-5-16-10(6)12-9(14)7-2-1-4-15-7/h1-5H,(H2,11,13)(H,12,14) OEIOSAFYCBYSPX-UHFFFAOYSA-N AuxInfo=1/1/N:15,14,9,16,12,8,10,13,11,7,6,5,4,3,2,1/rA:16SSOONNCCCCCCCCCC/rB:;;;;;s1s5;d-7;s8;s2;d3s5s10;s1d-9;d4s6s8;d-10;s14;s2d-15;/rC:5.9019,-1.83,0;5.1499,1.8455,0;6.8249,-.2422,0;3.1249,-.5429,0;5.0929,-.2422,0;2.5897,-2.1901,0;5.0929,-1.2422,0;4.2839,-1.83,0;4.5929,-2.7811,0;5.9589,1.2578,0;5.9589,.2578,0;5.5929,-2.7811,0;3.3328,-1.521,0;6.7679,1.8455,0;6.4589,2.7966,0;5.4589,2.7966,0; | |
| CID2972189 CC1NC(=O)NC1CCCCCC(=O)Nc2ccc(C)cc2 InChI=1S/C17H25N3O2/c1-12-8-10-14(11-9-12)19-16(21)7-5-3-4-6-15-13(2)18-17(22)20-15/h8-11,13,15H,3-7H2,1-2H3,(H,19,21)(H2,18,20,22) TWUHJIAGJSKONL-UHFFFAOYSA-N AuxInfo=1/1/N:22,11,10,9,13,8,14,20,21,17,18,19,7,16,6,15,12,4,5,3,2,1/E:(8,9)(10,11)/rA:22OONNNCCCCCCCCCCCCCCCCC/rB:;;;;s3;s4s6;s6;s8;s9;s7;d1s3s4;s10;s13;d2s5s14;s5;d+16;s16;;s17d-19;d-18s19;s19;/rC:7.8195,5.558,0;4.5981,-1.558,0;6.4347,4.4365,0;7.9128,3.7784,0;2.866,-1.558,0;6.3301,3.442,0;7.2437,3.0353,0;5.4641,2.942,0;5.4641,1.942,0;4.5981,1.442,0;7.4516,2.0571,0;7.4128,4.6444,0;4.5981,.442,0;3.7321,-.058,0;3.7321,-1.058,0;2.866,-2.558,0;2,-3.058,0;3.7321,-3.058,0;2.866,-4.558,0;2,-4.058,0;3.7321,-4.058,0;2.866,-5.558,0; | |
| CID2974150 CC1NC(=O)NC1CCCCCC(=O)NCCc2ccccc2 InChI=1S/C18H27N3O2/c1-14-16(21-18(23)20-14)10-6-3-7-11-17(22)19-13-12-15-8-4-2-5-9-15/h2,4-5,8-9,14,16H,3,6-7,10-13H2,1H3,(H,19,22)(H2,20,21,23) ZUWQXYDMMUZDNB-UHFFFAOYSA-N AuxInfo=1/1/N:11,23,10,21,22,9,13,19,20,8,14,17,16,7,18,6,15,12,5,4,3,2,1/E:(4,5)(8,9)/rA:23OONNNCCCCCCCCCCCCCCCCCC/rB:;;;;s3;s4s6;s6;s8;s9;s7;d1s3s4;s10;s13;d2s5s14;s5;s16;s17;d+18;s18;s19;d-20;d-21s22;/rC:8.6856,5.808,0;5.4641,-1.308,0;7.3007,4.6865,0;8.7788,4.0284,0;3.7321,-1.308,0;7.1962,3.692,0;8.1097,3.2853,0;6.3301,3.192,0;6.3301,2.192,0;5.4641,1.692,0;8.3176,2.3071,0;8.2788,4.8944,0;5.4641,.692,0;4.5981,.192,0;4.5981,-.808,0;3.7321,-2.308,0;2.866,-2.808,0;2.866,-3.808,0;3.7321,-4.308,0;2,-4.308,0;3.7321,-5.308,0;2,-5.308,0;2.866,-5.808,0; | |
| CID3236317 CC(=O)c1ccc(NC(=O)C2CC(=NO2)c3ccc(F)cc3)cc1 InChI=1S/C18H15FN2O3/c1-11(22)12-4-8-15(9-5-12)20-18(23)17-10-16(21-24-17)13-2-6-14(19)7-3-13/h2-9,17H,10H2,1H3,(H,20,23) LEGVOMLQZWNAFK-UHFFFAOYSA-N AuxInfo=1/1/N:24,13,14,20,21,18,19,15,16,8,23,17,11,22,12,9,7,10,1,6,5,4,3,2/E:(2,3)(4,5)(6,7)(8,9)/rA:24FOOONNCCCCCCCCCCCCCCCCCC/rB:;;;s2;;s2;s7;d-5s8;d3s6s7;s9;s6;d+11;s11;d+12;s12;;s13;d-14;s15d-17;d-16s17;s1d+18s19;d4s17;s23;/rC:2,5.3875,0;5.6602,1.2003,0;5.7172,-.8875,0;4.8511,-5.3875,0;5.3511,2.1514,0;3.9851,-.8875,0;4.8511,.6125,0;4.0421,1.2003,0;4.3511,2.1514,0;4.8511,-.3875,0;3.7634,2.9604,0;3.9851,-1.8875,0;4.1701,3.874,0;2.7688,2.8559,0;3.1191,-2.3875,0;4.8511,-2.3875,0;3.9851,-3.8875,0;3.5823,4.683,0;2.1811,3.6649,0;3.1191,-3.3875,0;4.8511,-3.3875,0;2.5878,4.5784,0;3.9851,-4.8875,0;3.1191,-5.3875,0; | |
| CID3236465 COc1cc(CN\C(=C(/C#N)\C(=O)N)\C)cc(OC)c1OC InChI=1S/C15H19N3O4/c1-9(11(7-16)15(17)19)18-8-10-5-12(20-2)14(22-4)13(6-10)21-3/h5-6,18H,8H2,1-4H3,(H2,17,19)/b11-9+ URGRWBAQWQWSPE-PKNBQFBNSA-N AuxInfo=1/1/N:16,18,19,20,11,10,22,9,15,8,17,12,13,14,21,7,6,5,4,1,2,3/E:(2,3)(5,6)(12,13)(20,21)/rA:22OOOONNNCCCCCCCCCCCCCCC/rB:;;;;;;;s5s8;d+8;s8;s1d+11;s2s10;s3s12d-13;s5;s15;d+15;s1;s2;s3;d4s6s17;t7s17;/rC:7.1962,2.81,0;3.7321,2.81,0;5.4641,3.81,0;4.5981,-3.69,0;4.5981,-.69,0;2.866,-3.69,0;2,-1.19,0;5.4641,.81,0;5.4641,-.19,0;4.5981,1.31,0;6.3301,1.31,0;6.3301,2.31,0;4.5981,2.31,0;5.4641,2.81,0;4.5981,-1.69,0;5.4641,-2.19,0;3.7321,-2.19,0;8.0622,2.31,0;2.866,2.31,0;6.3301,4.31,0;3.7321,-3.19,0;2.866,-1.69,0; | |
| CID3238045 CCn1ncc(C2=NOC(C2)C(=O)Nc3ccccc3C(=O)OC)c1C InChI=1S/C18H20N4O4/c1-4-22-11(2)13(10-19-22)15-9-16(26-21-15)17(23)20-14-8-6-5-7-12(14)18(24)25-3/h5-8,10,16H,4,9H2,1-3H3,(H,20,23) QXCMRVUGCPGZBQ-UHFFFAOYSA-N AuxInfo=1/1/N:19,17,26,16,24,23,22,21,9,15,13,20,12,18,11,10,14,25,7,8,6,5,2,4,3,1/rA:26OOOONNNNCCCCCCCCCCCCCCCCCC/rB:;;;;s1;s5;;;s1s9;d-6s9;s11;s5d+12;d2s8s10;d-7s12;s5;s13;s8;s16;s18;d+18;d-20;s21;s22d-23;s3d4s20;s3;/rC:7.1391,.5447,0;7.1962,-1.543,0;2.866,-3.043,0;3.7321,-1.543,0;3.9333,3.2559,0;6.8301,1.4958,0;4.7423,3.8437,0;5.4641,-1.543,0;5.5211,.5447,0;6.3301,-.043,0;5.8301,1.4958,0;5.2423,2.3048,0;4.2423,2.3048,0;6.3301,-1.043,0;5.5514,3.2559,0;2.9823,3.5649,0;3.6546,1.4958,0;5.4641,-2.543,0;2.7744,4.543,0;4.5981,-3.043,0;6.3301,-3.043,0;4.5981,-4.043,0;6.3301,-4.043,0;5.4641,-4.543,0;3.7321,-2.543,0;2,-2.543,0; | |
| CID3238372 O=C(N1CCN(CC1)c2ccccc2)c3ccc(CN4C(=O)Nc5ccccc5C4=O)cc3 InChI=1S/C26H24N4O3/c31-24(29-16-14-28(15-17-29)21-6-2-1-3-7-21)20-12-10-19(11-13-20)18-30-25(32)22-8-4-5-9-23(22)27-26(30)33/h1-13H,14-18H2,(H,27,33) IGDCKRNSWXEZDI-UHFFFAOYSA-N AuxInfo=1/1/N:26,23,24,32,33,15,16,30,31,21,22,18,19,8,9,10,11,20,17,14,12,27,28,13,25,29,7,4,5,6,1,2,3/E:(2,3)(6,7)(10,11)(12,13)(14,15)(16,17)/rA:33OOONNNNCCCCCCCCCCCCCCCCCCCCCCCCCC/rB:;;;;;;s4;s4;s5s8;s5s9;s4;d1s5;s13;d+12;s12;;d+14;s14;s6s17;d+17s18;s17d-19;s15;d-16;d2s6;d-23s24;s25;s7s27;d3s6s7;d+27;d+28;s30;s31d-32;/rC:7.1962,2.25,0;12.3923,-1.75,0;10.6603,1.25,0;4.5981,-.25,0;6.3301,.75,0;11.5263,-.25,0;12.3923,1.25,0;4.5981,.75,0;5.4641,-.75,0;5.4641,1.25,0;6.3301,-.25,0;3.7321,-.75,0;7.1962,1.25,0;8.0622,.75,0;3.7321,-1.75,0;2.866,-.25,0;9.7942,-.25,0;8.0622,-.25,0;8.9282,1.25,0;10.6603,-.75,0;8.9282,-.75,0;9.7942,.75,0;2.866,-2.25,0;2,-.75,0;12.3923,-.75,0;2,-1.75,0;13.2583,-.25,0;13.2583,.75,0;11.5263,.75,0;14.1523,-.7847,0;14.1523,1.2847,0;15.0583,-.2708,0;15.0583,.7708,0; | |
| CID3239708 COc1cccc(C2=NOC(C2)C(=O)Nc3cc(OC)c(OC)c(OC)c3)c1OC InChI=1S/C21H24N2O7/c1-25-15-8-6-7-13(19(15)28-4)14-11-18(30-23-14)21(24)22-12-9-16(26-2)20(29-5)17(10-12)27-3/h6-10,18H,11H2,1-5H3,(H,22,24) YGWFWAPUTWVGDK-UHFFFAOYSA-N AuxInfo=1/1/N:27,28,29,26,30,19,16,22,21,20,11,17,13,12,18,23,24,10,15,25,14,9,8,3,4,5,6,2,7,1/E:(2,3)(9,10)(16,17)(26,27)/rA:30OOOOOOONNCCCCCCCCCCCCCCCCCCCCC/rB:;;;;;;s1;;s1;s10;d-8s11;s12;d3s9s10;s2d-13;s13;s9;s4s15;d-16;d+17;s17;d+18s19;s5d+21;s6s20;s7s23d-24;s2;s4;s5;s6;s7;/rC:4.6551,.6913,0;5.1506,3.4694,0;6.3301,-1.3965,0;6.3262,5.0875,0;2.866,-4.3965,0;6.3301,-4.3965,0;4.5981,-5.3965,0;4.9641,1.6424,0;4.5981,-1.3965,0;5.4641,.1035,0;6.2731,.6913,0;5.9641,1.6424,0;6.5519,2.4514,0;5.4641,-.8965,0;6.1452,3.3649,0;7.5464,2.3468,0;4.5981,-2.3965,0;6.7329,4.1739,0;8.1342,3.1559,0;5.4641,-2.8965,0;3.7321,-2.8965,0;7.7275,4.0694,0;3.7321,-3.8965,0;5.4641,-3.8965,0;4.5981,-4.3965,0;4.7439,4.383,0;6.914,5.8965,0;2,-3.8965,0;7.1962,-3.8965,0;3.7321,-5.8965,0; | |
| CID3240660 CCn1cc(C2=NOC(C2)C(=O)Nc3ccccc3C(=O)OC)c(C)n1 InChI=1S/C18H20N4O4/c1-4-22-10-13(11(2)20-22)15-9-16(26-21-15)17(23)19-14-8-6-5-7-12(14)18(24)25-3/h5-8,10,16H,4,9H2,1-3H3,(H,19,23) MEAHRPUDLXWXHN-UHFFFAOYSA-N AuxInfo=1/1/N:19,17,26,16,24,23,22,21,9,14,13,20,12,18,11,10,15,25,8,7,6,5,2,4,3,1/rA:26OOOONNNNCCCCCCCCCCCCCCCCCC/rB:;;;;s1;s5;;;s1s9;d-6s9;s11;d-7s12;s5d+12;d2s8s10;s5;s13;s8;s16;s18;d+18;d-20;s21;s22d-23;s3d4s20;s3;/rC:7.1391,.5447,0;7.1962,-1.543,0;2.866,-3.043,0;3.7321,-1.543,0;3.9333,3.2559,0;6.8301,1.4958,0;4.7423,3.8437,0;5.4641,-1.543,0;5.5211,.5447,0;6.3301,-.043,0;5.8301,1.4958,0;5.2423,2.3048,0;5.5514,3.2559,0;4.2423,2.3048,0;6.3301,-1.043,0;2.9823,3.5649,0;6.5024,3.5649,0;5.4641,-2.543,0;2.7744,4.543,0;4.5981,-3.043,0;6.3301,-3.043,0;4.5981,-4.043,0;6.3301,-4.043,0;5.4641,-4.543,0;3.7321,-2.543,0;2,-2.543,0; | |
| CID3240978 COc1cccc(c1)C2=NOC(C2)C(=O)Nc3ccc(cc3)C(=O)C InChI=1S/C19H18N2O4/c1-12(22)13-6-8-15(9-7-13)20-19(23)18-11-17(21-25-18)14-4-3-5-16(10-14)24-2/h3-10,18H,11H2,1-2H3,(H,20,23) CRFORAJNMDQJTB-UHFFFAOYSA-N AuxInfo=1/1/N:24,25,16,13,19,21,22,17,18,12,8,23,20,10,14,15,9,7,11,6,5,4,2,3,1/E:(6,7)(8,9)/rA:25OOOONNCCCCCCCCCCCCCCCCCCC/rB:;;;s1;;s1;s7;d-5s8;s9;d2s6s7;d+10;s10;s6;s3s12;d-13;d+14;s14;d+15s16;;s17d-20;d-18s20;d4s20;s23;s3;/rC:2.923,1.5526,0;4.5981,-.5352,0;7.3967,3.9126,0;3.7321,-5.0352,0;3.2321,2.5036,0;2.866,-.5352,0;3.7321,.9648,0;4.5411,1.5526,0;4.2321,2.5036,0;4.8198,3.3127,0;3.7321,-.0352,0;5.8144,3.2081,0;4.4131,4.2262,0;2.866,-1.5352,0;6.4021,4.0171,0;5.0009,5.0352,0;2,-2.0352,0;3.7321,-2.0352,0;5.9954,4.9307,0;2.866,-3.5352,0;2,-3.0352,0;3.7321,-3.0352,0;2.866,-4.5352,0;2,-5.0352,0;7.9845,4.7216,0; | |
| CID3241191 COc1cc(cc(OC)c1OC)C(=O)NCc2cn3ccccc3n2 InChI=1S/C18H19N3O4/c1-23-14-8-12(9-15(24-2)17(14)25-3)18(22)19-10-13-11-21-7-5-4-6-16(21)20-13/h4-9,11H,10H2,1-3H3,(H,19,22) KBEXGPXJYAOGCF-UHFFFAOYSA-N AuxInfo=1/1/N:23,24,25,22,21,17,14,16,15,9,11,12,8,18,19,10,20,13,6,7,5,4,1,2,3/E:(1,2)(8,9)(14,15)(23,24)/rA:25OOOONNNCCCCCCCCCCCCCCCCCC/rB:;;;;;;s7;s6s8;s5d-7;s5d-8;;d4s6s12;s5;d+12;s12;s10;s1d+16;s2s15;s3s18d-19;d-14;d-17s21;s1;s2;s3;/rC:7.7619,-2.2321,0;10.7619,-.5,0;9.7619,-2.2321,0;8.2619,2.0981,0;3.7321,2.5981,0;6.7619,1.2321,0;4.6783,1.2933,0;5.2619,2.0981,0;6.2619,2.0981,0;3.7321,1.5981,0;4.6783,2.9028,0;8.2619,.366,0;7.7619,1.2321,0;2.866,3.0981,0;9.2619,.366,0;7.7619,-.5,0;2.866,1.0981,0;8.2619,-1.366,0;9.7619,-.5,0;9.2619,-1.366,0;2,2.5981,0;2,1.5981,0;8.2619,-3.0981,0;11.2619,.366,0;10.7619,-2.2321,0; | |
| CID3241493 COc1cccc(c1)C2=NOC(C2)C(=O)Nc3ccc(OC)c(OC)c3 InChI=1S/C19H20N2O5/c1-23-14-6-4-5-12(9-14)15-11-18(26-21-15)19(22)20-13-7-8-16(24-2)17(10-13)25-3/h4-10,18H,11H2,1-3H3,(H,20,22) RUSNEHISXMHECV-UHFFFAOYSA-N AuxInfo=1/1/N:24,26,25,18,15,20,19,23,13,17,9,12,14,16,10,22,21,8,11,7,6,2,3,5,4,1/rA:26OOOOONNCCCCCCCCCCCCCCCCCCC/rB:;;;;s1;;s1;s8;d-6s9;d2s7s8;s10;d+12;s7;s12;s3s13;d+14;d-15;s14;d+16s18;s4s17;s5d-21;d-19s22;s3;s4;s5;/rC:4.6551,1.5526,0;6.3301,-.5352,0;9.1287,3.9126,0;2.866,-3.5352,0;4.5981,-4.5352,0;4.9641,2.5036,0;4.5981,-.5352,0;5.4641,.9648,0;6.2731,1.5526,0;5.9641,2.5036,0;5.4641,-.0352,0;6.5519,3.3127,0;7.5464,3.2081,0;4.5981,-1.5352,0;6.1452,4.2262,0;8.1342,4.0171,0;3.7321,-2.0352,0;6.7329,5.0352,0;5.4641,-2.0352,0;7.7275,4.9307,0;3.7321,-3.0352,0;4.5981,-3.5352,0;5.4641,-3.0352,0;9.7165,4.7216,0;2,-3.0352,0;5.4641,-5.0352,0; | |
| CID3242057 On1c2ccccc2nc3c(N=O)c4ccccc4c13 InChI=1S/C15H9N3O2/c19-17-13-9-5-1-2-6-10(9)15-14(13)16-11-7-3-4-8-12(11)18(15)20/h1-8,20H OCERACDICRUDGM-UHFFFAOYSA-N AuxInfo=1/0/N:18,16,20,19,14,13,17,15,9,7,12,11,10,8,6,4,5,3,2,1/rA:20OONNNCCCCCCCCCCCCCCC/rB:;s1;;d2;s3;d+6;d-4s6;s7;s5s8d+9;s3;s4s11;s7;s9;d+11;d-13;d+12;d-14s16;s15;s17d-19;/rC:6.9814,-.3563,0;2,-1.0614,0;6.1154,.1437,0;4.3834,1.1437,0;2.6678,-.3171,0;5.2494,-.3563,0;5.0402,-1.3281,0;4.3834,.1437,0;4.0515,-1.4311,0;3.6463,-.5234,0;6.1154,1.1437,0;5.2494,1.6437,0;5.6609,-2.1568,0;3.615,-2.3701,0;7.0254,1.6506,0;5.2463,-3.1056,0;5.2333,2.6852,0;4.2164,-3.213,0;7.0334,2.6922,0;6.1314,3.213,0; | |
| CID3242510 COC(=O)c1ccccc1NC(=O)C2CC(=NO2)c3ccc(F)cc3 InChI=1S/C18H15FN2O4/c1-24-18(23)13-4-2-3-5-14(13)20-17(22)16-10-15(21-25-16)11-6-8-12(19)9-7-11/h2-9,16H,10H2,1H3,(H,20,22) XISIMBLMRHMUEM-UHFFFAOYSA-N AuxInfo=1/1/N:25,23,22,20,17,14,15,18,19,9,12,21,16,13,10,8,11,24,1,7,6,3,5,4,2/E:(6,7)(8,9)/rA:25FOOOONNCCCCCCCCCCCCCCCCCC/rB:;;;;s2;;s2;s8;d-6s9;d3s7s8;s10;s7;d+12;s12;s13;d+13;s14;d-15;d-16;s1d+18s19;s17;s20d-22;s4d5s16;s4;/rC:9.1813,4.6375,0;5.5211,.4503,0;7.1962,-1.6375,0;2.866,-3.1375,0;3.7321,-1.6375,0;5.8301,1.4014,0;5.4641,-1.6375,0;6.3301,-.1375,0;7.1391,.4503,0;6.8301,1.4014,0;6.3301,-1.1375,0;7.4179,2.2104,0;5.4641,-2.6375,0;7.0112,3.1239,0;8.4124,2.1059,0;4.5981,-3.1375,0;6.3301,-3.1375,0;7.599,3.933,0;9.0002,2.9149,0;4.5981,-4.1375,0;8.5935,3.8284,0;6.3301,-4.1375,0;5.4641,-4.6375,0;3.7321,-2.6375,0;2,-2.6375,0; | |
| CID3242979 COc1cccc(c1)C2=NOC(C2)C(=O)Nc3cc(OC)c(OC)c(OC)c3 InChI=1S/C20H22N2O6/c1-24-14-7-5-6-12(8-14)15-11-18(28-22-15)20(23)21-13-9-16(25-2)19(27-4)17(10-13)26-3/h5-10,18H,11H2,1-4H3,(H,21,23) NGCBEKFBQMYJMY-UHFFFAOYSA-N AuxInfo=1/1/N:28,25,26,27,23,16,24,15,18,17,10,13,14,19,11,20,21,9,22,12,8,7,2,5,3,4,6,1/E:(2,3)(9,10)(16,17)(25,26)/rA:28OOOOOONNCCCCCCCCCCCCCCCCCCCC/rB:;;;;;s1;;s1;s9;d-7s10;d2s8s9;s11;s8;d+13;s13;d+14;s14;s5s15;s3d+18;s4s17;s6s20d-21;d-16;d+19s23;s3;s4;s6;s5;/rC:6.2731,.6913,0;6.3301,-1.3965,0;2.866,-4.3965,0;6.3301,-4.3965,0;4.602,5.0875,0;4.5981,-5.3965,0;5.9641,1.6424,0;4.5981,-1.3965,0;5.4641,.1035,0;4.6551,.6913,0;4.9641,1.6424,0;5.4641,-.8965,0;4.3763,2.4514,0;4.5981,-2.3965,0;4.7831,3.3649,0;3.3818,2.3468,0;5.4641,-2.8965,0;3.7321,-2.8965,0;4.1953,4.1739,0;3.7321,-3.8965,0;5.4641,-3.8965,0;4.5981,-4.3965,0;2.794,3.1559,0;3.2008,4.0694,0;2,-3.8965,0;7.1962,-3.8965,0;3.7321,-5.8965,0;4.0142,5.8965,0; | |
| CID3243409 Fc1ccc(cc1)C2=NOC(C2)C(=O)Nc3ccc(cc3)C#N InChI=1S/C17H12FN3O2/c18-13-5-3-12(4-6-13)15-9-16(23-21-15)17(22)20-14-7-1-11(10-19)2-8-14/h1-8,16H,9H2,(H,20,22) TUYHAXDPQNIKOQ-UHFFFAOYSA-N AuxInfo=1/1/N:20,21,12,13,15,16,17,18,8,23,22,11,19,14,9,7,10,1,6,5,4,3,2/E:(1,2)(3,4)(5,6)(7,8)/rA:23FOONNNCCCCCCCCCCCCCCCCC/rB:;;s2;;;s2;s7;d-4s8;d3s5s7;s9;d+11;s11;s5;s12;d-13;d+14;s14;s1d+15s16;s17;d-18;d-20s21;t6s22;/rC:6.5832,5.6375,0;2.923,1.4503,0;4.5981,-.6375,0;3.2321,2.4014,0;2.866,-.6375,0;2.866,-5.6375,0;3.7321,.8625,0;4.5411,1.4503,0;4.2321,2.4014,0;3.7321,-.1375,0;4.8198,3.2104,0;5.8144,3.1059,0;4.4131,4.124,0;2.866,-1.6375,0;6.4021,3.9149,0;5.0009,4.933,0;3.7321,-2.1375,0;2,-2.1375,0;5.9954,4.8284,0;3.7321,-3.1375,0;2,-3.1375,0;2.866,-3.6375,0;2.866,-4.6375,0; | |
| CID3243453 CCc1ccc(cc1)N2C(=Nc3[nH]ncc3C2=O)SCC(=O)Nc4cc(C)[nH]n4 InChI=1S/C19H19N7O2S/c1-3-12-4-6-13(7-5-12)26-18(28)14-9-20-25-17(14)22-19(26)29-10-16(27)21-15-8-11(2)23-24-15/h4-9H,3,10H2,1-2H3,(H,20,25)(H2,21,23,24,27) IBJKHYZJWUJLKC-UHFFFAOYSA-N AuxInfo=1/1/N:24,29,21,19,20,17,18,28,22,23,27,15,11,12,26,25,16,13,14,7,8,5,9,10,6,4,3,2,1/E:(4,5)(6,7)/rA:29SOONNNNNNNCCCCCCCCCCCCCCCCCCC/rB:;;;;;s6;;;s9;s4;;d2s4s12;s1s4d+5;;s5s6d-12;d+11;s11;d-15s17;s15d-18;s15;d-7s12;s1;s21;d3s8s23;s8d+10;s9;s26d-27;s27;/rC:5.9313,.308,0;7.6634,3.308,0;4.1993,-.692,0;6.7974,1.808,0;7.6634,.308,0;9.4756,.5033,0;10.0592,1.308,0;5.0653,-2.192,0;2.6166,-3.0284,0;3.2857,-2.2853,0;5.9313,2.308,0;8.5294,1.808,0;7.6634,2.308,0;6.7974,.808,0;4.1993,3.308,0;8.5294,.808,0;5.9313,3.308,0;5.0653,1.808,0;5.0653,3.808,0;4.1993,2.308,0;3.3333,3.808,0;9.4756,2.1127,0;5.9313,-.692,0;3.3333,4.808,0;5.0653,-1.192,0;4.1993,-2.692,0;3.1166,-3.8944,0;4.0948,-3.6865,0;2.7099,-4.808,0; | |
| CID3243778 O=C1Nc2cccnc2Sc3ccccc13 InChI=1S/C12H8N2OS/c15-11-8-4-1-2-6-10(8)16-12-9(14-11)5-3-7-13-12/h1-7H,(H,14,15) FTMBGAIUQQPJDQ-UHFFFAOYSA-N AuxInfo=1/1/N:13,14,15,10,12,11,16,5,7,6,9,8,4,3,2,1/rA:16SONNCCCCCCCCCCCC/rB:;;;;s1s5;s3;s1s4d-7;d2s3s5;d-5;d+6;s7;s10;s11d-13;d-12;d-4s15;/rC:4.883,-1.4027,0;3.9491,1.689,0;5.383,.788,0;6.5365,-1.689,0;3.7595,.0062,0;3.982,-.9688,0;6.0065,.0061,0;5.784,-.9688,0;4.383,.788,0;2.769,.3285,0;3.2295,-1.6889,0;6.997,.3285,0;2,-.3741,0;2.2318,-1.3896,0;7.766,-.3741,0;7.5342,-1.3896,0; | |
| CID3349764 NC(=O)c1oc2ccccc2c1NC(=O)c3occc3 InChI=1S/C14H10N2O4/c15-13(17)12-11(8-4-1-2-5-9(8)20-12)16-14(18)10-6-3-7-19-10/h1-7H,(H2,15,17)(H,16,18) VRCCQQNVDLIJGO-UHFFFAOYSA-N AuxInfo=1/1/N:13,14,19,11,12,18,20,7,9,17,8,10,16,15,6,5,4,3,2,1/rA:20OOOONNCCCCCCCCCCCCCC/rB:;;;;;;s5s7;s1s7;s1d+8;d+7;d+9;s11;s12d-13;d3s5;d4s6s10;s2s15;d-17;s18;s2d-19;/rC:4.6783,-2.6373,0;5.5833,1.9249,0;3.3426,.4608,0;6.7619,-.9665,0;4.9889,-.0773,0;6.7619,-2.6986,0;3.7321,-1.3326,0;4.6783,-1.0278,0;3.7321,-2.3326,0;5.2619,-1.8326,0;2.866,-.8326,0;2.866,-2.8326,0;2,-1.3326,0;2,-2.3326,0;4.3211,.667,0;6.2619,-1.8326,0;4.6318,1.6175,0;4.0454,2.4275,0;4.6346,3.2355,0;5.5851,2.9249,0; | |
| CID4907320 O=C(C1CCC(CN2C(=O)Nc3ccccc3C2=O)CC1)N4CCN(CC4)c5ccccc5 InChI=1S/C26H30N4O3/c31-24(29-16-14-28(15-17-29)21-6-2-1-3-7-21)20-12-10-19(11-13-20)18-30-25(32)22-8-4-5-9-23(22)27-26(30)33/h1-9,19-20H,10-18H2,(H,27,33) BPEZFHQODUPVMF-UHFFFAOYSA-N AuxInfo=1/1/N:33,29,30,31,32,25,26,27,28,10,11,12,13,18,19,16,17,14,8,9,22,23,24,15,20,21,7,6,4,5,1,2,3/E:(2,3)(6,7)(10,11)(12,13)(14,15)(16,17)/rA:33OOONNNNCCCCCCCCCCCCCCCCCCCCCCCCCC/rB:;;;;;;;;s8;s8;s9s10;s9s11;s5s8;d1s4s9;s4;s4;s6s16;s6s17;d2s5;d3s5s7;s6;s20;s7s23;d+22;s22;d+23;d+24;s25;d-26;s27;s28d-31;d-29s30;/rC:7.1962,2.25,0;12.3923,-1.75,0;10.6603,1.25,0;6.3301,.75,0;11.5263,-.25,0;4.5981,-.25,0;12.3923,1.25,0;9.7942,-.25,0;8.0622,.75,0;8.9282,-.75,0;9.7942,.75,0;8.0622,-.25,0;8.9282,1.25,0;10.6603,-.75,0;7.1962,1.25,0;5.4641,1.25,0;6.3301,-.25,0;4.5981,.75,0;5.4641,-.75,0;12.3923,-.75,0;11.5263,.75,0;3.7321,-.75,0;13.2583,-.25,0;13.2583,.75,0;3.7321,-1.75,0;2.866,-.25,0;14.1523,-.7847,0;14.1523,1.2847,0;2.866,-2.25,0;2,-.75,0;15.0583,-.2708,0;15.0583,.7708,0;2,-1.75,0; | |
| CID5144290 COCCCNC(=O)c1ccc(CN2C(=O)Nc3ccccc3C2=O)cc1 InChI=1S/C20H21N3O4/c1-27-12-4-11-21-18(24)15-9-7-14(8-10-15)13-23-19(25)16-5-2-3-6-17(16)22-20(23)26/h2-3,5-10H,4,11-13H2,1H3,(H,21,24)(H,22,26) IONFHWANFSEYKJ-UHFFFAOYSA-N AuxInfo=1/1/N:27,25,26,18,21,22,14,15,19,20,17,24,8,9,16,10,12,23,11,13,7,6,5,4,1,2,3/E:(7,8)(9,10)/rA:27OOOONNNCCCCCCCCCCCCCCCCCCCC/rB:;;;;;;s5;s8;;d1s5s10;s6s10;d2s5s6;d+9;s9;;s7;s17;s14d-16;d-15s16;d+10;d+12;d4s7s16;s3s18;s21;s22d-25;s3;/rC:12.3923,-2,0;10.6603,1,0;2.866,.5,0;7.1962,2,0;11.5263,-.5,0;12.3923,1,0;6.3301,.5,0;10.6603,-1,0;9.7942,-.5,0;13.2583,-.5,0;12.3923,-1,0;13.2583,.5,0;11.5263,.5,0;8.9282,-1,0;9.7942,.5,0;8.0622,.5,0;5.4641,1,0;4.5981,.5,0;8.0622,-.5,0;8.9282,1,0;14.1523,-1.0347,0;14.1523,1.0347,0;7.1962,1,0;3.7321,1,0;15.0583,-.5208,0;15.0583,.5208,0;2,1,0; | |
| CID5309978 CNC(=O)c1ccsc1NC(=O)c2ccccc2 InChI=1S/C13H12N2O2S/c1-14-12(17)10-7-8-18-13(10)15-11(16)9-5-3-2-4-6-9/h2-8H,1H3,(H,14,17)(H,15,16) JPNMQJFTAFUPFW-UHFFFAOYSA-N AuxInfo=1/1/N:18,17,15,16,13,14,9,12,8,6,10,11,7,5,4,2,3,1/E:(3,4)(5,6)/rA:18SOONNCCCCCCCCCCCCC/rB:;;;;;s1s4d-6;;s6;d2s4s8;d3s5s6;s1d-9;d+8;s8;s13;d-14;d-15s16;s5;/rC:2.923,2.0606,0;2,.4728,0;5.7,.7734,0;3.7321,.4728,0;6.2353,2.4207,0;4.5411,2.0606,0;3.7321,1.4728,0;2.866,-1.0272,0;4.2321,3.0117,0;2.866,-.0272,0;5.4921,1.7516,0;3.2321,3.0117,0;3.7321,-1.5272,0;2,-1.5272,0;3.7321,-2.5272,0;2,-2.5272,0;2.866,-3.0272,0;7.1863,2.1117,0; | |
| CID5310086 COC(=O)c1ccsc1NC(=O)C2=COCCO2 InChI=1S/C11H11NO5S/c1-15-11(14)7-2-5-18-10(7)12-9(13)8-6-16-3-4-17-8/h2,5-6H,3-4H2,1H3,(H,12,13) IMATXVPNABHDDN-UHFFFAOYSA-N AuxInfo=1/1/N:18,15,9,8,16,14,12,10,13,11,17,7,5,6,4,3,2,1/rA:18SOOOOONCCCCCCCCCCC/rB:;;;;;;s2;s3s8;s2;s1s7;d-11;d5s7s10;s3d-10;s12;s1d-15;s4d6s12;s4;/rC:4.1759,-1.7293,0;7.7445,-.7348,0;7.7445,1.2652,0;2.2079,.9591,0;6.0125,-1.7348,0;3.9021,1.3192,0;5.1465,-.2348,0;8.6106,-.2348,0;8.6106,.7652,0;6.8785,-.2348,0;4.2804,-.7348,0;3.3669,-.3281,0;6.0125,-.7348,0;6.8785,.7652,0;2.6977,-1.0712,0;3.1977,-1.9372,0;3.159,.6501,0;2,1.9372,0; | |
| CID5310693 ClC1=CC2=C3CCC4=CNNC4=C3N=C2C=C1 InChI=1S/C13H10ClN3/c14-8-2-4-11-10(5-8)9-3-1-7-6-15-17-12(7)13(9)16-11/h2,4-6,15,17H,1,3H2 LBUOZLUCXKERAY-UHFFFAOYSA-N AuxInfo=1/0/N:7,17,6,15,14,13,9,16,5,11,12,10,8,1,4,3,2/rA:17ClNNNCCCCCCCCCCCCC/rB:;;s2;;s5;s6;s3s5;s7;s2d-8s9;d+5;d-3s11;s4d+9;s11;s12;s1d+14;d-15s16;/rC:2,-.8087,0;8.0519,.1565,0;6.0305,-1.0106,0;8.6356,.9612,0;5.3737,.4612,0;5.3737,1.4612,0;6.2397,1.9612,0;6.2397,-.0388,0;7.1057,1.4612,0;7.1057,.4612,0;4.6367,-.2059,0;5.0418,-1.1137,0;8.0519,1.7659,0;3.6086,-.0827,0;4.4469,-1.9612,0;2.9942,-.9162,0;3.4162,-1.8618,0; | |
| CID5389994 O=C1C(=C2C=CNC=C2)C(=O)c3ccccc13 InChI=1S/C14H9NO2/c16-13-10-3-1-2-4-11(10)14(17)12(13)9-5-7-15-8-6-9/h1-8,15H RFJVOUZINWUTIG-UHFFFAOYSA-N AuxInfo=1/0/N:14,15,10,11,12,13,16,17,9,5,6,4,7,8,3,1,2/E:(1,2)(3,4)(5,6)(7,8)(10,11)(13,14)(16,17)/rA:17OONCCCCCCCCCCCCCC/rB:;;;;s5;d1s4s5;d2s4s6;d4;d-5;d-6;s9;s9;s10;s11d-14;s3d-12;s3d-13;/rC:4.9889,1.7553,0;4.9889,-1.7553,0;8.2619,0,0;5.2619,0,0;3.7321,.5,0;3.7321,-.5,0;4.6783,.8047,0;4.6783,-.8047,0;6.2619,0,0;2.866,1,0;2.866,-1,0;6.7619,-.866,0;6.7619,.866,0;2,.5,0;2,-.5,0;7.7619,-.866,0;7.7619,.866,0; | |
| CID6398908 COC(=O)c1cccc2\C(=N\O)\c3ccccc3c12 InChI=1S/C15H11NO3/c1-19-15(17)12-8-4-7-11-13(12)9-5-2-3-6-10(9)14(11)16-18/h2-8,18H,1H3/b16-14+ NGVLXRBIJYFIFM-JQIJEIRASA-N AuxInfo=1/0/N:19,16,17,15,12,13,11,14,6,8,7,10,5,9,18,4,3,2,1/rA:19OOONCCCCCCCCCCCCCCC/rB:;;s2;;s5;d-5;s6;d+4s7s8;s5;s7;d+6;d-8;d-10;d-11s14;s12;s13d-16;s1d3s10;s1;/rC:6.0528,-2.5972,0;3.6613,2.9246,0;4.4118,-2.043,0;4.5274,2.4246,0;5.0274,-.1142,0;4.0274,-.1142,0;5.3364,.8368,0;3.7183,.8368,0;4.5274,1.4246,0;5.7123,-.899,0;6.3518,1.0691,0;3.3424,-.899,0;2.7029,1.0691,0;6.7328,-.6902,0;7.0547,.3004,0;2.3219,-.6902,0;2,.3004,0;5.3923,-1.8464,0;5.7328,-3.5446,0; |
This file contains bidirectional Unicode text that may be interpreted or compiled differently than what appears below. To review, open the file in an editor that reveals hidden Unicode characters.
Learn more about bidirectional Unicode characters
| ScaffoldID ParentID Type | |
| c873ee8329bf80eb3cc195ed22969ccb CID0300385 Framework | |
| 975f4ba64117f4dc65044299552ee698 c873ee8329bf80eb3cc195ed22969ccb Scaffold | |
| 8fd26b68cfaae505375844904e5b1381 c873ee8329bf80eb3cc195ed22969ccb Scaffold | |
| 3a11fd53d0cb855cf451ea49efe8d460 CID0588806 Framework | |
| a5597429da941f0ce03b09b2c85b9882 CID0649913 Framework | |
| 975f4ba64117f4dc65044299552ee698 a5597429da941f0ce03b09b2c85b9882 Scaffold | |
| b8178eed34519faaa8dedaa326dfe20c a5597429da941f0ce03b09b2c85b9882 Scaffold | |
| 42ead4d8dd5f589a39ab1e9dbec935d3 CID0651058 Framework | |
| 8abb699660fda4e35d3e3afd23b38c5b 42ead4d8dd5f589a39ab1e9dbec935d3 Scaffold | |
| 975f4ba64117f4dc65044299552ee698 8abb699660fda4e35d3e3afd23b38c5b Scaffold | |
| da17eef9c95f82cea74d8894be49c35c 8abb699660fda4e35d3e3afd23b38c5b Scaffold | |
| 174da7f6329bd280a00a02dcd9233ce2 42ead4d8dd5f589a39ab1e9dbec935d3 Scaffold | |
| 975f4ba64117f4dc65044299552ee698 174da7f6329bd280a00a02dcd9233ce2 Scaffold | |
| da17eef9c95f82cea74d8894be49c35c 174da7f6329bd280a00a02dcd9233ce2 Scaffold | |
| 42ead4d8dd5f589a39ab1e9dbec935d3 CID0651323 Framework | |
| 8abb699660fda4e35d3e3afd23b38c5b 42ead4d8dd5f589a39ab1e9dbec935d3 Scaffold | |
| 975f4ba64117f4dc65044299552ee698 8abb699660fda4e35d3e3afd23b38c5b Scaffold | |
| da17eef9c95f82cea74d8894be49c35c 8abb699660fda4e35d3e3afd23b38c5b Scaffold | |
| 174da7f6329bd280a00a02dcd9233ce2 42ead4d8dd5f589a39ab1e9dbec935d3 Scaffold | |
| 975f4ba64117f4dc65044299552ee698 174da7f6329bd280a00a02dcd9233ce2 Scaffold | |
| da17eef9c95f82cea74d8894be49c35c 174da7f6329bd280a00a02dcd9233ce2 Scaffold | |
| 01cbf5467388a22e021136e4a7c47480 CID0658703 Framework | |
| 670c032e552eaed14add44e4081bdb5f 01cbf5467388a22e021136e4a7c47480 Scaffold | |
| 975f4ba64117f4dc65044299552ee698 670c032e552eaed14add44e4081bdb5f Scaffold | |
| 9a68289770b7fc063275a16837cafdd3 670c032e552eaed14add44e4081bdb5f Scaffold | |
| 30b1e74ecda4bd95d75ccedf10a08149 01cbf5467388a22e021136e4a7c47480 Scaffold | |
| 9a68289770b7fc063275a16837cafdd3 30b1e74ecda4bd95d75ccedf10a08149 Scaffold | |
| 9a68289770b7fc063275a16837cafdd3 30b1e74ecda4bd95d75ccedf10a08149 Scaffold | |
| 975f4ba64117f4dc65044299552ee698 CID0658795 Framework | |
| 10c777de13dddb7e794b401a972a05a6 CID0660128 Framework | |
| 3d8508f8b5131434401c6f148c4af2ef 10c777de13dddb7e794b401a972a05a6 Scaffold | |
| 24de1a183d4478cf3bcaeca97d753809 10c777de13dddb7e794b401a972a05a6 Scaffold | |
| 99e0e84683345c4ec90517680b9f622a CID0661045 Framework | |
| 975f4ba64117f4dc65044299552ee698 99e0e84683345c4ec90517680b9f622a Scaffold | |
| 3d8508f8b5131434401c6f148c4af2ef 99e0e84683345c4ec90517680b9f622a Scaffold | |
| fa6a105a8d9aa69190e9de59f245a67d CID0661441 Framework | |
| 072a18219e6feaad99c1a19d1132f6aa CID0793991 Framework | |
| bfd4449ee209813b3839173bcd0158ef CID0796100 Framework | |
| ab4a4a9ed33b0272756de2aaab4bb4fc bfd4449ee209813b3839173bcd0158ef Scaffold | |
| 975f4ba64117f4dc65044299552ee698 ab4a4a9ed33b0272756de2aaab4bb4fc Scaffold | |
| cc63f2cfcc0f3c1e706c844d9a876fdc ab4a4a9ed33b0272756de2aaab4bb4fc Scaffold | |
| 17d5be9654a3ae72eacc5edc6b607080 bfd4449ee209813b3839173bcd0158ef Scaffold | |
| cc63f2cfcc0f3c1e706c844d9a876fdc 17d5be9654a3ae72eacc5edc6b607080 Scaffold | |
| 7c891d254363d5829cb85af68b969b93 17d5be9654a3ae72eacc5edc6b607080 Scaffold | |
| 054a9517d568855186ae239eaf56e2bd CID0979869 Framework | |
| 8eb95a1236462a6ce873328bfc0603fd 054a9517d568855186ae239eaf56e2bd Scaffold | |
| 975f4ba64117f4dc65044299552ee698 8eb95a1236462a6ce873328bfc0603fd Scaffold | |
| 3f1e40af8f16eb36d4ae912bd6a0f8a9 8eb95a1236462a6ce873328bfc0603fd Scaffold | |
| 20df0bcadef2df3b222f642b0c6d257b 054a9517d568855186ae239eaf56e2bd Scaffold | |
| 975f4ba64117f4dc65044299552ee698 20df0bcadef2df3b222f642b0c6d257b Scaffold | |
| 7e7e16cd1ce8dacb18666c9eb77c8ebf 20df0bcadef2df3b222f642b0c6d257b Scaffold | |
| 7f5437ed98d6dd75212a20b34b5a6b0b CID1045996 Framework | |
| 975f4ba64117f4dc65044299552ee698 7f5437ed98d6dd75212a20b34b5a6b0b Scaffold | |
| 78ddb0a0e10cd070f20594c88bbdee5b 7f5437ed98d6dd75212a20b34b5a6b0b Scaffold | |
| d4a8e0d4c9e3b8a810794585c829c098 CID1087003 Framework | |
| 975f4ba64117f4dc65044299552ee698 d4a8e0d4c9e3b8a810794585c829c098 Scaffold | |
| 5c29a527b8ce48c5244428c45e0eb2ca d4a8e0d4c9e3b8a810794585c829c098 Scaffold | |
| e2508c5fea214f7f203c76570220a5fe CID1245872 Framework | |
| e0e3a983c2b85ca246aba9eed73e6e56 e2508c5fea214f7f203c76570220a5fe Scaffold | |
| 975f4ba64117f4dc65044299552ee698 e0e3a983c2b85ca246aba9eed73e6e56 Scaffold | |
| d99b36c7b27eb7f45a4d14450838b99f e0e3a983c2b85ca246aba9eed73e6e56 Scaffold | |
| f184951d84977f951422edb39f22a7a4 e2508c5fea214f7f203c76570220a5fe Scaffold | |
| 7e7e16cd1ce8dacb18666c9eb77c8ebf f184951d84977f951422edb39f22a7a4 Scaffold | |
| d99b36c7b27eb7f45a4d14450838b99f f184951d84977f951422edb39f22a7a4 Scaffold | |
| b0e91348daaa7c347c60407b14301413 CID1288597 Framework | |
| 643e3d670b29e54e5a7de478bbc61050 b0e91348daaa7c347c60407b14301413 Scaffold | |
| 975f4ba64117f4dc65044299552ee698 643e3d670b29e54e5a7de478bbc61050 Scaffold | |
| 9fd6316e1fa32a68bad213ab29b9cbc6 643e3d670b29e54e5a7de478bbc61050 Scaffold | |
| 101abff128d88bec4f0293b7b3f917c3 b0e91348daaa7c347c60407b14301413 Scaffold | |
| 9fd6316e1fa32a68bad213ab29b9cbc6 101abff128d88bec4f0293b7b3f917c3 Scaffold | |
| db3ca4ae93bd3757765b3157600d4ec2 101abff128d88bec4f0293b7b3f917c3 Scaffold | |
| 73e1edb1dbd829f3e154979356931b42 CID1294440 Framework | |
| 20df0bcadef2df3b222f642b0c6d257b 73e1edb1dbd829f3e154979356931b42 Scaffold | |
| 975f4ba64117f4dc65044299552ee698 20df0bcadef2df3b222f642b0c6d257b Scaffold | |
| 7e7e16cd1ce8dacb18666c9eb77c8ebf 20df0bcadef2df3b222f642b0c6d257b Scaffold | |
| 8e5295a85098cb87609909986116d329 73e1edb1dbd829f3e154979356931b42 Scaffold | |
| 975f4ba64117f4dc65044299552ee698 8e5295a85098cb87609909986116d329 Scaffold | |
| 2a1e87e1fb9fceb219dac9955813476d 8e5295a85098cb87609909986116d329 Scaffold | |
| 3350e932a354c2938d51278a6493e212 CID2091134 Framework | |
| 975f4ba64117f4dc65044299552ee698 3350e932a354c2938d51278a6493e212 Scaffold | |
| d99b36c7b27eb7f45a4d14450838b99f 3350e932a354c2938d51278a6493e212 Scaffold | |
| a94a364c950eaf7335995a858f4b7563 CID2099071 Framework | |
| 8fd26b68cfaae505375844904e5b1381 a94a364c950eaf7335995a858f4b7563 Scaffold | |
| df44bbb29c413006e6717a7e5ec170be a94a364c950eaf7335995a858f4b7563 Scaffold | |
| 9b7a43092627a21adf439a7fe1cdd4c0 CID2377706 Framework | |
| c487efa88b73cdf71cf5ab000483e66d 9b7a43092627a21adf439a7fe1cdd4c0 Scaffold | |
| 975f4ba64117f4dc65044299552ee698 c487efa88b73cdf71cf5ab000483e66d Scaffold | |
| 8fd26b68cfaae505375844904e5b1381 c487efa88b73cdf71cf5ab000483e66d Scaffold | |
| 0d7298e921b55ad800887a9d9d2c8cfd 9b7a43092627a21adf439a7fe1cdd4c0 Scaffold | |
| 975f4ba64117f4dc65044299552ee698 0d7298e921b55ad800887a9d9d2c8cfd Scaffold | |
| 5817ffe29c00416e2ba8f318a49b0c76 0d7298e921b55ad800887a9d9d2c8cfd Scaffold | |
| dfe2ec1575009f565e527a1df490eaec CID2501747 Framework | |
| d7c6776de6938346824efba70f5236bc dfe2ec1575009f565e527a1df490eaec Scaffold | |
| 975f4ba64117f4dc65044299552ee698 d7c6776de6938346824efba70f5236bc Scaffold | |
| da17eef9c95f82cea74d8894be49c35c d7c6776de6938346824efba70f5236bc Scaffold | |
| 2cdc80409f6e832f7c450ddb3d5adde3 dfe2ec1575009f565e527a1df490eaec Scaffold | |
| 975f4ba64117f4dc65044299552ee698 2cdc80409f6e832f7c450ddb3d5adde3 Scaffold | |
| d99b36c7b27eb7f45a4d14450838b99f 2cdc80409f6e832f7c450ddb3d5adde3 Scaffold | |
| e0a339f1cbba6046e8d3a102250a8053 CID2575371 Framework | |
| 1493c1f8bd0d8d84f54cd07f82a0c31f e0a339f1cbba6046e8d3a102250a8053 Scaffold | |
| d99b36c7b27eb7f45a4d14450838b99f e0a339f1cbba6046e8d3a102250a8053 Scaffold | |
| 2dbccf15c4f468e03105bc89bc6c81c4 CID2589475 Framework | |
| d99b36c7b27eb7f45a4d14450838b99f 2dbccf15c4f468e03105bc89bc6c81c4 Scaffold | |
| c9a64c2b6b439d407be202ee4f92a57f 2dbccf15c4f468e03105bc89bc6c81c4 Scaffold | |
| 78eee4faff1df40d6559274b8bc7dc61 CID2953401 Framework | |
| 6091d48034cb7a1a4b56f2dc5a76e8ca 78eee4faff1df40d6559274b8bc7dc61 Scaffold | |
| fe38e3bdec5284810b667455fd818c11 78eee4faff1df40d6559274b8bc7dc61 Scaffold | |
| 5201ac792b3bcd90179ae65513215c6d CID2962251 Framework | |
| 7c924f2df12056e57941902b94e2bb84 5201ac792b3bcd90179ae65513215c6d Scaffold | |
| 975f4ba64117f4dc65044299552ee698 7c924f2df12056e57941902b94e2bb84 Scaffold | |
| 11aaedc2f20849840c0bc1ee2f6444c9 7c924f2df12056e57941902b94e2bb84 Scaffold | |
| ecacfc8ed6b53e1cdf646bea15ddbed2 5201ac792b3bcd90179ae65513215c6d Scaffold | |
| 7c891d254363d5829cb85af68b969b93 ecacfc8ed6b53e1cdf646bea15ddbed2 Scaffold | |
| 11aaedc2f20849840c0bc1ee2f6444c9 ecacfc8ed6b53e1cdf646bea15ddbed2 Scaffold | |
| cbfdca105b99b0e90612573701c40099 CID2971411 Framework | |
| d99b36c7b27eb7f45a4d14450838b99f cbfdca105b99b0e90612573701c40099 Scaffold | |
| d99b36c7b27eb7f45a4d14450838b99f cbfdca105b99b0e90612573701c40099 Scaffold | |
| e2887801a3fbfba2b59313a471f08bce CID2972189 Framework | |
| 975f4ba64117f4dc65044299552ee698 e2887801a3fbfba2b59313a471f08bce Scaffold | |
| e7b7b2ec1a06327f79dfd3f5e7eba881 e2887801a3fbfba2b59313a471f08bce Scaffold | |
| 2389523f5f67eba9cee747be241de84c CID2974150 Framework | |
| 975f4ba64117f4dc65044299552ee698 2389523f5f67eba9cee747be241de84c Scaffold | |
| e7b7b2ec1a06327f79dfd3f5e7eba881 2389523f5f67eba9cee747be241de84c Scaffold | |
| 29cdf5c0c83ae572657e02035f8160df CID3236317 Framework | |
| 99c8f3cc3c37fc77166d94424d7068d0 29cdf5c0c83ae572657e02035f8160df Scaffold | |
| 975f4ba64117f4dc65044299552ee698 99c8f3cc3c37fc77166d94424d7068d0 Scaffold | |
| 11aaedc2f20849840c0bc1ee2f6444c9 99c8f3cc3c37fc77166d94424d7068d0 Scaffold | |
| 7c924f2df12056e57941902b94e2bb84 29cdf5c0c83ae572657e02035f8160df Scaffold | |
| 975f4ba64117f4dc65044299552ee698 7c924f2df12056e57941902b94e2bb84 Scaffold | |
| 11aaedc2f20849840c0bc1ee2f6444c9 7c924f2df12056e57941902b94e2bb84 Scaffold | |
| 975f4ba64117f4dc65044299552ee698 CID3236465 Framework | |
| 8aed330af7b7230f1ee1d365b08a724a CID3238045 Framework | |
| 99c8f3cc3c37fc77166d94424d7068d0 8aed330af7b7230f1ee1d365b08a724a Scaffold | |
| 975f4ba64117f4dc65044299552ee698 99c8f3cc3c37fc77166d94424d7068d0 Scaffold | |
| 11aaedc2f20849840c0bc1ee2f6444c9 99c8f3cc3c37fc77166d94424d7068d0 Scaffold | |
| 1312b3fce60a60f6e09573b0cd86fa11 8aed330af7b7230f1ee1d365b08a724a Scaffold | |
| 7c891d254363d5829cb85af68b969b93 1312b3fce60a60f6e09573b0cd86fa11 Scaffold | |
| 11aaedc2f20849840c0bc1ee2f6444c9 1312b3fce60a60f6e09573b0cd86fa11 Scaffold | |
| 01d04f2e8fea9755d66f4e99fb24879a CID3238372 Framework | |
| cbacff1d995d080f456bbe8158299b60 01d04f2e8fea9755d66f4e99fb24879a Scaffold | |
| 21de7aa9202c6880f6aaf4cdb8126047 cbacff1d995d080f456bbe8158299b60 Scaffold | |
| 975f4ba64117f4dc65044299552ee698 21de7aa9202c6880f6aaf4cdb8126047 Scaffold | |
| 3f1e40af8f16eb36d4ae912bd6a0f8a9 21de7aa9202c6880f6aaf4cdb8126047 Scaffold | |
| 8eb95a1236462a6ce873328bfc0603fd cbacff1d995d080f456bbe8158299b60 Scaffold | |
| 975f4ba64117f4dc65044299552ee698 8eb95a1236462a6ce873328bfc0603fd Scaffold | |
| 3f1e40af8f16eb36d4ae912bd6a0f8a9 8eb95a1236462a6ce873328bfc0603fd Scaffold | |
| 71bb28f08435cf9d5832509cc5221c29 01d04f2e8fea9755d66f4e99fb24879a Scaffold | |
| 21de7aa9202c6880f6aaf4cdb8126047 71bb28f08435cf9d5832509cc5221c29 Scaffold | |
| 975f4ba64117f4dc65044299552ee698 21de7aa9202c6880f6aaf4cdb8126047 Scaffold | |
| 3f1e40af8f16eb36d4ae912bd6a0f8a9 21de7aa9202c6880f6aaf4cdb8126047 Scaffold | |
| a4ee5402101863e76690a4b49fc6b285 71bb28f08435cf9d5832509cc5221c29 Scaffold | |
| 975f4ba64117f4dc65044299552ee698 a4ee5402101863e76690a4b49fc6b285 Scaffold | |
| 2aaf56f7ddcc2902d0694bf1e1bc1a4c a4ee5402101863e76690a4b49fc6b285 Scaffold | |
| 29cdf5c0c83ae572657e02035f8160df CID3239708 Framework | |
| 99c8f3cc3c37fc77166d94424d7068d0 29cdf5c0c83ae572657e02035f8160df Scaffold | |
| 975f4ba64117f4dc65044299552ee698 99c8f3cc3c37fc77166d94424d7068d0 Scaffold | |
| 11aaedc2f20849840c0bc1ee2f6444c9 99c8f3cc3c37fc77166d94424d7068d0 Scaffold | |
| 7c924f2df12056e57941902b94e2bb84 29cdf5c0c83ae572657e02035f8160df Scaffold | |
| 975f4ba64117f4dc65044299552ee698 7c924f2df12056e57941902b94e2bb84 Scaffold | |
| 11aaedc2f20849840c0bc1ee2f6444c9 7c924f2df12056e57941902b94e2bb84 Scaffold | |
| 8aed330af7b7230f1ee1d365b08a724a CID3240660 Framework | |
| 99c8f3cc3c37fc77166d94424d7068d0 8aed330af7b7230f1ee1d365b08a724a Scaffold | |
| 975f4ba64117f4dc65044299552ee698 99c8f3cc3c37fc77166d94424d7068d0 Scaffold | |
| 11aaedc2f20849840c0bc1ee2f6444c9 99c8f3cc3c37fc77166d94424d7068d0 Scaffold | |
| 1312b3fce60a60f6e09573b0cd86fa11 8aed330af7b7230f1ee1d365b08a724a Scaffold | |
| 7c891d254363d5829cb85af68b969b93 1312b3fce60a60f6e09573b0cd86fa11 Scaffold | |
| 11aaedc2f20849840c0bc1ee2f6444c9 1312b3fce60a60f6e09573b0cd86fa11 Scaffold | |
| 29cdf5c0c83ae572657e02035f8160df CID3240978 Framework | |
| 99c8f3cc3c37fc77166d94424d7068d0 29cdf5c0c83ae572657e02035f8160df Scaffold | |
| 975f4ba64117f4dc65044299552ee698 99c8f3cc3c37fc77166d94424d7068d0 Scaffold | |
| 11aaedc2f20849840c0bc1ee2f6444c9 99c8f3cc3c37fc77166d94424d7068d0 Scaffold | |
| 7c924f2df12056e57941902b94e2bb84 29cdf5c0c83ae572657e02035f8160df Scaffold | |
| 975f4ba64117f4dc65044299552ee698 7c924f2df12056e57941902b94e2bb84 Scaffold | |
| 11aaedc2f20849840c0bc1ee2f6444c9 7c924f2df12056e57941902b94e2bb84 Scaffold | |
| df2b7ab094a87bc8572f2a93245cc143 CID3241191 Framework | |
| 975f4ba64117f4dc65044299552ee698 df2b7ab094a87bc8572f2a93245cc143 Scaffold | |
| 033408fa6f2da115c78b23e747fd3ab7 df2b7ab094a87bc8572f2a93245cc143 Scaffold | |
| 29cdf5c0c83ae572657e02035f8160df CID3241493 Framework | |
| 99c8f3cc3c37fc77166d94424d7068d0 29cdf5c0c83ae572657e02035f8160df Scaffold | |
| 975f4ba64117f4dc65044299552ee698 99c8f3cc3c37fc77166d94424d7068d0 Scaffold | |
| 11aaedc2f20849840c0bc1ee2f6444c9 99c8f3cc3c37fc77166d94424d7068d0 Scaffold | |
| 7c924f2df12056e57941902b94e2bb84 29cdf5c0c83ae572657e02035f8160df Scaffold | |
| 975f4ba64117f4dc65044299552ee698 7c924f2df12056e57941902b94e2bb84 Scaffold | |
| 11aaedc2f20849840c0bc1ee2f6444c9 7c924f2df12056e57941902b94e2bb84 Scaffold | |
| 1fd83cde3f06c185bc941490ee8890db CID3242057 Framework | |
| 29cdf5c0c83ae572657e02035f8160df CID3242510 Framework | |
| 99c8f3cc3c37fc77166d94424d7068d0 29cdf5c0c83ae572657e02035f8160df Scaffold | |
| 975f4ba64117f4dc65044299552ee698 99c8f3cc3c37fc77166d94424d7068d0 Scaffold | |
| 11aaedc2f20849840c0bc1ee2f6444c9 99c8f3cc3c37fc77166d94424d7068d0 Scaffold | |
| 7c924f2df12056e57941902b94e2bb84 29cdf5c0c83ae572657e02035f8160df Scaffold | |
| 975f4ba64117f4dc65044299552ee698 7c924f2df12056e57941902b94e2bb84 Scaffold | |
| 11aaedc2f20849840c0bc1ee2f6444c9 7c924f2df12056e57941902b94e2bb84 Scaffold | |
| 29cdf5c0c83ae572657e02035f8160df CID3242979 Framework | |
| 99c8f3cc3c37fc77166d94424d7068d0 29cdf5c0c83ae572657e02035f8160df Scaffold | |
| 975f4ba64117f4dc65044299552ee698 99c8f3cc3c37fc77166d94424d7068d0 Scaffold | |
| 11aaedc2f20849840c0bc1ee2f6444c9 99c8f3cc3c37fc77166d94424d7068d0 Scaffold | |
| 7c924f2df12056e57941902b94e2bb84 29cdf5c0c83ae572657e02035f8160df Scaffold | |
| 975f4ba64117f4dc65044299552ee698 7c924f2df12056e57941902b94e2bb84 Scaffold | |
| 11aaedc2f20849840c0bc1ee2f6444c9 7c924f2df12056e57941902b94e2bb84 Scaffold | |
| 29cdf5c0c83ae572657e02035f8160df CID3243409 Framework | |
| 99c8f3cc3c37fc77166d94424d7068d0 29cdf5c0c83ae572657e02035f8160df Scaffold | |
| 975f4ba64117f4dc65044299552ee698 99c8f3cc3c37fc77166d94424d7068d0 Scaffold | |
| 11aaedc2f20849840c0bc1ee2f6444c9 99c8f3cc3c37fc77166d94424d7068d0 Scaffold | |
| 7c924f2df12056e57941902b94e2bb84 29cdf5c0c83ae572657e02035f8160df Scaffold | |
| 975f4ba64117f4dc65044299552ee698 7c924f2df12056e57941902b94e2bb84 Scaffold | |
| 11aaedc2f20849840c0bc1ee2f6444c9 7c924f2df12056e57941902b94e2bb84 Scaffold | |
| 7df889cf3090dd28a740cf525515e548 CID3243453 Framework | |
| 643e3d670b29e54e5a7de478bbc61050 7df889cf3090dd28a740cf525515e548 Scaffold | |
| 975f4ba64117f4dc65044299552ee698 643e3d670b29e54e5a7de478bbc61050 Scaffold | |
| 9fd6316e1fa32a68bad213ab29b9cbc6 643e3d670b29e54e5a7de478bbc61050 Scaffold | |
| d74401a8f144f39c195285ee6eb18145 7df889cf3090dd28a740cf525515e548 Scaffold | |
| 7c891d254363d5829cb85af68b969b93 d74401a8f144f39c195285ee6eb18145 Scaffold | |
| 9fd6316e1fa32a68bad213ab29b9cbc6 d74401a8f144f39c195285ee6eb18145 Scaffold | |
| 20d9aca84c9b17ad63a8c274354b4e7d CID3243778 Framework | |
| 7e667a8d739c5684451ff6ea30e88e4d CID3349764 Framework | |
| 7e7e16cd1ce8dacb18666c9eb77c8ebf 7e667a8d739c5684451ff6ea30e88e4d Scaffold | |
| 78ddb0a0e10cd070f20594c88bbdee5b 7e667a8d739c5684451ff6ea30e88e4d Scaffold | |
| 4a08f289a6c8134658ba7073554142bc CID4907320 Framework | |
| 31ddc00c30f086a77c816fdf9bb1bdeb 4a08f289a6c8134658ba7073554142bc Scaffold | |
| 8eb95a1236462a6ce873328bfc0603fd 31ddc00c30f086a77c816fdf9bb1bdeb Scaffold | |
| 975f4ba64117f4dc65044299552ee698 8eb95a1236462a6ce873328bfc0603fd Scaffold | |
| 3f1e40af8f16eb36d4ae912bd6a0f8a9 8eb95a1236462a6ce873328bfc0603fd Scaffold | |
| b83f7597ebb402a410173b2aee56ed00 31ddc00c30f086a77c816fdf9bb1bdeb Scaffold | |
| 6091d48034cb7a1a4b56f2dc5a76e8ca b83f7597ebb402a410173b2aee56ed00 Scaffold | |
| 3f1e40af8f16eb36d4ae912bd6a0f8a9 b83f7597ebb402a410173b2aee56ed00 Scaffold | |
| e4f83a9cd9f7026a8ef8d5905eae9336 4a08f289a6c8134658ba7073554142bc Scaffold | |
| b83f7597ebb402a410173b2aee56ed00 e4f83a9cd9f7026a8ef8d5905eae9336 Scaffold | |
| 6091d48034cb7a1a4b56f2dc5a76e8ca b83f7597ebb402a410173b2aee56ed00 Scaffold | |
| 3f1e40af8f16eb36d4ae912bd6a0f8a9 b83f7597ebb402a410173b2aee56ed00 Scaffold | |
| ccced1275bc2c9648f783b5d0ad3fec4 e4f83a9cd9f7026a8ef8d5905eae9336 Scaffold | |
| 6091d48034cb7a1a4b56f2dc5a76e8ca ccced1275bc2c9648f783b5d0ad3fec4 Scaffold | |
| 2aaf56f7ddcc2902d0694bf1e1bc1a4c ccced1275bc2c9648f783b5d0ad3fec4 Scaffold | |
| a4ee5402101863e76690a4b49fc6b285 CID5144290 Framework | |
| 975f4ba64117f4dc65044299552ee698 a4ee5402101863e76690a4b49fc6b285 Scaffold | |
| 2aaf56f7ddcc2902d0694bf1e1bc1a4c a4ee5402101863e76690a4b49fc6b285 Scaffold | |
| 2cdc80409f6e832f7c450ddb3d5adde3 CID5309978 Framework | |
| 975f4ba64117f4dc65044299552ee698 2cdc80409f6e832f7c450ddb3d5adde3 Scaffold | |
| d99b36c7b27eb7f45a4d14450838b99f 2cdc80409f6e832f7c450ddb3d5adde3 Scaffold | |
| 0855b3ee4a7a6ed698da64c4879b33f9 CID5310086 Framework | |
| 84bd282b34e612b8e8cbc975b9b58883 0855b3ee4a7a6ed698da64c4879b33f9 Scaffold | |
| d99b36c7b27eb7f45a4d14450838b99f 0855b3ee4a7a6ed698da64c4879b33f9 Scaffold | |
| e05d6d734fcf736e7eec582717589f7c CID5310693 Framework | |
| 072a18219e6feaad99c1a19d1132f6aa CID5389994 Framework | |
| de9d0ae5a36d91dbd0e88be5862bc9e1 CID6398908 Framework |
This file contains bidirectional Unicode text that may be interpreted or compiled differently than what appears below. To review, open the file in an editor that reveals hidden Unicode characters.
Learn more about bidirectional Unicode characters
| Hashkey Smiles Size SID | |
| c873ee8329bf80eb3cc195ed22969ccb c1ccc(cc1)c2n[nH]c3ccccc23 15 SCF0000001 | |
| 975f4ba64117f4dc65044299552ee698 c1ccccc1 6 SCF0000002 | |
| 8fd26b68cfaae505375844904e5b1381 c1ccc2[nH]ncc2c1 9 SCF0000003 | |
| 3a11fd53d0cb855cf451ea49efe8d460 c1ccc2ncncc2c1 10 SCF0000004 | |
| a5597429da941f0ce03b09b2c85b9882 Nc1ccnc(SCC(=O)Nc2ccccc2)n1 18 SCF0000005 | |
| b8178eed34519faaa8dedaa326dfe20c Nc1ccncn1 7 SCF0000006 | |
| 42ead4d8dd5f589a39ab1e9dbec935d3 O=C(CN1CCC(CC1)NC(=O)c2ccccc2)Nc3ccccc3 25 SCF0000007 | |
| 8abb699660fda4e35d3e3afd23b38c5b O=C(CN1CCCCC1)Nc2ccccc2 16 SCF0000008 | |
| da17eef9c95f82cea74d8894be49c35c C1CCNCC1 6 SCF0000009 | |
| 174da7f6329bd280a00a02dcd9233ce2 O=C(NC1CCNCC1)c2ccccc2 15 SCF0000010 | |
| 01cbf5467388a22e021136e4a7c47480 C(Nc1ccnc(NCc2cccnc2)c1)c3ccccc3 22 SCF0000011 | |
| 670c032e552eaed14add44e4081bdb5f C(Nc1ccncc1)c2ccccc2 14 SCF0000012 | |
| 9a68289770b7fc063275a16837cafdd3 c1ccncc1 6 SCF0000013 | |
| 30b1e74ecda4bd95d75ccedf10a08149 C(Nc1ccccn1)c2cccnc2 14 SCF0000014 | |
| 10c777de13dddb7e794b401a972a05a6 O=C1C=CC=CN1Cc2ccc3OCOc3c2 17 SCF0000015 | |
| 3d8508f8b5131434401c6f148c4af2ef O=C1NC=CC=C1 7 SCF0000016 | |
| 24de1a183d4478cf3bcaeca97d753809 C1Oc2ccccc2O1 9 SCF0000017 | |
| 99e0e84683345c4ec90517680b9f622a O=C1C=CC=CN1Cc2ccccc2 14 SCF0000018 | |
| fa6a105a8d9aa69190e9de59f245a67d c1ccc2ncccc2c1 10 SCF0000019 | |
| 072a18219e6feaad99c1a19d1132f6aa O=C1C(=C2C=CNC=C2)C(=O)c3ccccc13 17 SCF0000020 | |
| bfd4449ee209813b3839173bcd0158ef N(c1ccccc1)c2cc(ncn2)n3cccn3 18 SCF0000021 | |
| ab4a4a9ed33b0272756de2aaab4bb4fc N(c1ccccc1)c2ccncn2 13 SCF0000022 | |
| cc63f2cfcc0f3c1e706c844d9a876fdc c1cncnc1 6 SCF0000023 | |
| 17d5be9654a3ae72eacc5edc6b607080 c1cnn(c1)c2ccncn2 11 SCF0000024 | |
| 7c891d254363d5829cb85af68b969b93 c1cn[nH]c1 5 SCF0000025 | |
| 054a9517d568855186ae239eaf56e2bd O=C(Nc1ccccc1N2CCNCC2)c3occc3 20 SCF0000026 | |
| 8eb95a1236462a6ce873328bfc0603fd C1CN(CCN1)c2ccccc2 12 SCF0000027 | |
| 3f1e40af8f16eb36d4ae912bd6a0f8a9 C1CNCCN1 6 SCF0000028 | |
| 20df0bcadef2df3b222f642b0c6d257b O=C(Nc1ccccc1)c2occc2 14 SCF0000029 | |
| 7e7e16cd1ce8dacb18666c9eb77c8ebf o1cccc1 5 SCF0000030 | |
| 7f5437ed98d6dd75212a20b34b5a6b0b O=C(Cc1ccccc1)Nc2coc3ccccc23 19 SCF0000031 | |
| 78ddb0a0e10cd070f20594c88bbdee5b o1ccc2ccccc12 9 SCF0000032 | |
| d4a8e0d4c9e3b8a810794585c829c098 O=C1NC(=O)c2c(N1)c3cnc4ccccc4n3c2c5ccccc5 25 SCF0000033 | |
| 5c29a527b8ce48c5244428c45e0eb2ca O=C1NC(=O)c2cn3c4ccccc4ncc3c2N1 19 SCF0000034 | |
| e2508c5fea214f7f203c76570220a5fe O=C(Nc1ccc(Cc2ccccc2)s1)c3occc3 20 SCF0000035 | |
| e0e3a983c2b85ca246aba9eed73e6e56 C(c1ccccc1)c2cccs2 12 SCF0000036 | |
| d99b36c7b27eb7f45a4d14450838b99f c1ccsc1 5 SCF0000037 | |
| f184951d84977f951422edb39f22a7a4 O=C(Nc1cccs1)c2occc2 13 SCF0000038 | |
| b0e91348daaa7c347c60407b14301413 O=C1N(C(=Nc2[nH]ncc12)SCc3cscn3)c4ccccc4 23 SCF0000039 | |
| 643e3d670b29e54e5a7de478bbc61050 O=C1N(C=Nc2[nH]ncc12)c3ccccc3 16 SCF0000040 | |
| 9fd6316e1fa32a68bad213ab29b9cbc6 O=C1NC=Nc2[nH]ncc12 10 SCF0000041 | |
| 101abff128d88bec4f0293b7b3f917c3 O=C1NC(=Nc2[nH]ncc12)SCc3cscn3 17 SCF0000042 | |
| db3ca4ae93bd3757765b3157600d4ec2 c1cscn1 5 SCF0000043 | |
| 73e1edb1dbd829f3e154979356931b42 O=C(Nc1ccccc1N2CCOCC2)c3occc3 20 SCF0000044 | |
| 8e5295a85098cb87609909986116d329 C1CN(CCO1)c2ccccc2 12 SCF0000045 | |
| 2a1e87e1fb9fceb219dac9955813476d C1COCCN1 6 SCF0000046 | |
| 3350e932a354c2938d51278a6493e212 O=C(Cc1ccccc1)Nc2cccs2 15 SCF0000047 | |
| a94a364c950eaf7335995a858f4b7563 O=C(OCc1nc2ccccc2[nH]1)c3n[nH]c4ccccc34 22 SCF0000048 | |
| df44bbb29c413006e6717a7e5ec170be c1ccc2[nH]cnc2c1 9 SCF0000049 | |
| 9b7a43092627a21adf439a7fe1cdd4c0 O=C(COC(=O)c1n[nH]c2ccccc12)Nc3ccc(cc3)S(=O)(=O)N4CCCC4 30 SCF0000050 | |
| c487efa88b73cdf71cf5ab000483e66d O=C(COC(=O)c1n[nH]c2ccccc12)Nc3ccccc3 22 SCF0000051 | |
| 0d7298e921b55ad800887a9d9d2c8cfd O=S(=O)(N1CCCC1)c2ccccc2 14 SCF0000052 | |
| 5817ffe29c00416e2ba8f318a49b0c76 C1CCNC1 5 SCF0000053 | |
| dfe2ec1575009f565e527a1df490eaec O=C(Nc1cccs1)c2ccc(cc2)S(=O)(=O)N3CCCCC3 23 SCF0000054 | |
| d7c6776de6938346824efba70f5236bc O=S(=O)(N1CCCCC1)c2ccccc2 15 SCF0000055 | |
| 2cdc80409f6e832f7c450ddb3d5adde3 O=C(Nc1cccs1)c2ccccc2 14 SCF0000056 | |
| e0a339f1cbba6046e8d3a102250a8053 O=C(CSC1=Nc2ccccc2C(=O)N1)Nc3cccs3 21 SCF0000057 | |
| 1493c1f8bd0d8d84f54cd07f82a0c31f O=C1NC=Nc2ccccc12 11 SCF0000058 | |
| 2dbccf15c4f468e03105bc89bc6c81c4 O=C(CSC1=Nc2sccc2C(=O)N1)Nc3cccs3 20 SCF0000059 | |
| c9a64c2b6b439d407be202ee4f92a57f O=C1NC=Nc2sccc12 10 SCF0000060 | |
| 78eee4faff1df40d6559274b8bc7dc61 O=C1N(CC2CCCCC2)C(=S)Nc3ccccc13 19 SCF0000061 | |
| 6091d48034cb7a1a4b56f2dc5a76e8ca C1CCCCC1 6 SCF0000062 | |
| fe38e3bdec5284810b667455fd818c11 O=C1NC(=S)Nc2ccccc12 12 SCF0000063 | |
| 5201ac792b3bcd90179ae65513215c6d O=C(Nc1cn[nH]c1)C2CC(=NO2)c3ccccc3 19 SCF0000064 | |
| 7c924f2df12056e57941902b94e2bb84 C1CC(=NO1)c2ccccc2 11 SCF0000065 | |
| 11aaedc2f20849840c0bc1ee2f6444c9 C1CC=NO1 5 SCF0000066 | |
| ecacfc8ed6b53e1cdf646bea15ddbed2 O=C(Nc1cn[nH]c1)C2CC=NO2 13 SCF0000067 | |
| cbfdca105b99b0e90612573701c40099 O=C(Nc1cccs1)c2cccs2 13 SCF0000068 | |
| e2887801a3fbfba2b59313a471f08bce O=C(CCCCCC1CNC(=O)N1)Nc2ccccc2 20 SCF0000069 | |
| e7b7b2ec1a06327f79dfd3f5e7eba881 O=C1NCCN1 6 SCF0000070 | |
| 2389523f5f67eba9cee747be241de84c O=C(CCCCCC1CNC(=O)N1)NCCc2ccccc2 22 SCF0000071 | |
| 29cdf5c0c83ae572657e02035f8160df O=C(Nc1ccccc1)C2CC(=NO2)c3ccccc3 20 SCF0000072 | |
| 99c8f3cc3c37fc77166d94424d7068d0 O=C(Nc1ccccc1)C2CC=NO2 14 SCF0000073 | |
| 8aed330af7b7230f1ee1d365b08a724a O=C(Nc1ccccc1)C2CC(=NO2)c3cn[nH]c3 19 SCF0000074 | |
| 1312b3fce60a60f6e09573b0cd86fa11 C1CC(=NO1)c2cn[nH]c2 10 SCF0000075 | |
| 01d04f2e8fea9755d66f4e99fb24879a O=C(N1CCN(CC1)c2ccccc2)c3ccc(CN4C(=O)Nc5ccccc5C4=O)cc3 33 SCF0000076 | |
| cbacff1d995d080f456bbe8158299b60 O=C(N1CCN(CC1)c2ccccc2)c3ccccc3 20 SCF0000077 | |
| 21de7aa9202c6880f6aaf4cdb8126047 O=C(N1CCNCC1)c2ccccc2 14 SCF0000078 | |
| 71bb28f08435cf9d5832509cc5221c29 O=C(N1CCNCC1)c2ccc(CN3C(=O)Nc4ccccc4C3=O)cc2 27 SCF0000079 | |
| a4ee5402101863e76690a4b49fc6b285 O=C1Nc2ccccc2C(=O)N1Cc3ccccc3 19 SCF0000080 | |
| 2aaf56f7ddcc2902d0694bf1e1bc1a4c O=C1NC(=O)c2ccccc2N1 12 SCF0000081 | |
| df2b7ab094a87bc8572f2a93245cc143 O=C(NCc1cn2ccccc2n1)c3ccccc3 19 SCF0000082 | |
| 033408fa6f2da115c78b23e747fd3ab7 c1ccn2ccnc2c1 9 SCF0000083 | |
| 1fd83cde3f06c185bc941490ee8890db c1ccc2c(c1)cc3nc4ccccc4[nH]c23 17 SCF0000084 | |
| 7df889cf3090dd28a740cf525515e548 O=C(CSC1=Nc2[nH]ncc2C(=O)N1c3ccccc3)Nc4cc[nH]n4 26 SCF0000085 | |
| d74401a8f144f39c195285ee6eb18145 O=C(CSC1=Nc2[nH]ncc2C(=O)N1)Nc3cc[nH]n3 20 SCF0000086 | |
| 20d9aca84c9b17ad63a8c274354b4e7d O=C1Nc2cccnc2Sc3ccccc13 16 SCF0000087 | |
| 7e667a8d739c5684451ff6ea30e88e4d O=C(Nc1coc2ccccc12)c3occc3 17 SCF0000088 | |
| 4a08f289a6c8134658ba7073554142bc O=C(C1CCC(CN2C(=O)Nc3ccccc3C2=O)CC1)N4CCN(CC4)c5ccccc5 33 SCF0000089 | |
| 31ddc00c30f086a77c816fdf9bb1bdeb O=C(C1CCCCC1)N2CCN(CC2)c3ccccc3 20 SCF0000090 | |
| b83f7597ebb402a410173b2aee56ed00 O=C(C1CCCCC1)N2CCNCC2 14 SCF0000091 | |
| e4f83a9cd9f7026a8ef8d5905eae9336 O=C(C1CCC(CN2C(=O)Nc3ccccc3C2=O)CC1)N4CCNCC4 27 SCF0000092 | |
| ccced1275bc2c9648f783b5d0ad3fec4 O=C1Nc2ccccc2C(=O)N1CC3CCCCC3 19 SCF0000093 | |
| 0855b3ee4a7a6ed698da64c4879b33f9 O=C(Nc1cccs1)C2=COCCO2 14 SCF0000094 | |
| 84bd282b34e612b8e8cbc975b9b58883 C1COC=CO1 6 SCF0000095 | |
| e05d6d734fcf736e7eec582717589f7c C1CC2=C3C=CC=CC3=NC2=C4NNC=C14 16 SCF0000096 | |
| de9d0ae5a36d91dbd0e88be5862bc9e1 N=C1c2ccccc2c3ccccc13 14 SCF0000097 |
This file contains bidirectional Unicode text that may be interpreted or compiled differently than what appears below. To review, open the file in an editor that reveals hidden Unicode characters.
Learn more about bidirectional Unicode characters
| CID Type Metric NumberOfClosest ClosestNames ClosestSimilarities | |
| CID0658795 SPFP4 Tanimoto 2 CID3236465 0.99 | |
| CID3241493 SPFP4 Tanimoto 6 CID3242979 0.99 | |
| CID0651058 SPFP4 Tanimoto 2 CID0651323 0.98 | |
| CID3238045 SPFP4 Tanimoto 2 CID3240660 0.98 | |
| CID3239708 SPFP4 Tanimoto 5 CID3242979 0.96 | |
| CID3239708 SPFP4 Tanimoto 5 CID3241493 0.95 | |
| CID3240978 SPFP4 Tanimoto 6 CID3241493 0.92 | |
| CID3240978 SPFP4 Tanimoto 6 CID3242979 0.91 | |
| CID3239708 SPFP4 Tanimoto 5 CID3240978 0.88 | |
| CID3236317 SPFP4 Tanimoto 7 CID3240978 0.86 | |
| CID3236317 SPFP4 Tanimoto 7 CID3243409 0.85 | |
| CID3236317 SPFP4 Tanimoto 7 CID3242510 0.83 | |
| CID0793991 SPFP4 Tanimoto 2 CID5389994 0.83 | |
| CID0660128 SPFP4 Tanimoto 2 CID0661045 0.82 | |
| CID2971411 SPFP4 Tanimoto 2 CID5309978 0.79 | |
| CID3236317 SPFP4 Tanimoto 7 CID3242979 0.78 | |
| CID3236317 SPFP4 Tanimoto 7 CID3241493 0.78 | |
| CID3242979 SPFP4 Tanimoto 6 CID3243409 0.76 | |
| CID3242510 SPFP4 Tanimoto 4 CID3243409 0.76 | |
| CID3241493 SPFP4 Tanimoto 6 CID3243409 0.76 | |
| CID3240978 SPFP4 Tanimoto 6 CID3242510 0.75 | |
| CID3236317 SPFP4 Tanimoto 7 CID3239708 0.75 | |
| CID3238045 FCFP6 Tanimoto 3 CID3242510 0.60 | |
| CID3240660 FCFP6 Tanimoto 3 CID3242510 0.60 |
Sign up for free
to join this conversation on GitHub.
Already have an account?
Sign in to comment