vbox crash Mac

Host OS: 10.11.2 (15C50)
Host Hardware:
  MacBook Air (13-inch, Early 2015)
  2.2 GHz Intel Core i7
  8 GB 1600 MHz DDR3
  Intel HD Graphics 6000 1536 MB
Guest OS: Linux 3.19.0-43-generic #49-Ubuntu (15.04)
Guest Image: Ubuntu Vagrant Cloud Image
Task: Heavy Disk IO (Indexing Files)
Happend 3 times over 3 months

Anonymous UUID:       72211C9E-462C-2DF7-0673-C533DCDF978B

Sun Jan 17 13:27:06 2016

*** Panic Report ***
panic(cpu 0 caller 0xffffff8013db01fa): "TLB invalidation IPI timeout: " "CPU(s) failed to respond to interrupts, unresponsive CPU bitmap: 0x4, NMIPI acks: orig: 0x0, now: 0x0"@/Library/Caches/com.apple.xbs/Sources/xnu/xnu-3248.20.55/osfmk/x86_64/pmap.c:2594
Backtrace (CPU 0), Frame : Return Address
0xffffff801fc9b980 : 0xffffff8013cde792 
0xffffff801fc9ba00 : 0xffffff8013db01fa 
0xffffff801fc9baa0 : 0xffffff8013db705b 
0xffffff801fc9bb90 : 0xffffff8013db7d86 
0xffffff801fc9bc00 : 0xffffff8013d63da5 
0xffffff801fc9bd10 : 0xffffff8013d5934c 
0xffffff801fc9bd40 : 0xffffff8013d54813 
0xffffff801fc9bd70 : 0xffffff8014258250 
0xffffff801fc9bd90 : 0xffffff80142df088 
0xffffff801fc9be00 : 0xffffff8013d9c509 
0xffffff801fc9be30 : 0xffffff8013ce2ef3 
0xffffff801fc9be60 : 0xffffff8013cc68a8 
0xffffff801fc9bea0 : 0xffffff8013cd62e5 
0xffffff801fc9bf10 : 0xffffff8013dbbd2a 
0xffffff801fc9bfb0 : 0xffffff8013defa56 

BSD process name corresponding to current thread: VBoxSVC

Mac OS version:
15C50

Kernel version:
Darwin Kernel Version 15.2.0: Fri Nov 13 19:56:56 PST 2015; root:xnu-3248.20.55~2/RELEASE_X86_64
Kernel UUID: 17EA3101-D2E4-31BF-BDA9-931F51049F93
Kernel slide:     0x0000000013a00000
Kernel text base: 0xffffff8013c00000
__HIB  text base: 0xffffff8013b00000
System model name: MacBookAir7,2 (Mac-937CB26E2E02BB01)

System uptime in nanoseconds: 136674841382567
last loaded kext at 44630612700387: com.apple.driver.usb.AppleUSBHostCompositeDevice	1.0.1 (addr 0xffffff7f968f2000, size 28672)
last unloaded kext at 44781776623446: com.apple.driver.usb.AppleUSBHostCompositeDevice	1.0.1 (addr 0xffffff7f968f2000, size 28672)
loaded kexts:
org.virtualbox.kext.VBoxNetAdp	5.0.12
org.virtualbox.kext.VBoxNetFlt	5.0.12
org.virtualbox.kext.VBoxUSB	5.0.12
org.virtualbox.kext.VBoxDrv	5.0.12
virtualcdrw.driver	1.0
at.obdev.nke.LittleSnitch	4358
com.apple.filesystems.autofs	3.0
com.apple.driver.AudioAUUC	1.70
com.apple.driver.AGPM	110.20.21
com.apple.driver.ApplePlatformEnabler	2.6.0d0
com.apple.driver.X86PlatformShim	1.0.0
com.apple.driver.AppleOSXWatchdog	1
com.apple.driver.AppleGraphicsDevicePolicy	3.7.7
com.apple.driver.AppleUpstreamUserClient	3.6.1
com.apple.driver.AppleHDA	272.51.3
com.apple.driver.pmtelemetry	1
com.apple.iokit.IOUserEthernet	1.0.1
com.apple.iokit.IOBluetoothSerialManager	4.4.3f4
com.apple.driver.AppleIntelBDWGraphics	10.1.2
com.apple.driver.AppleThunderboltIP	3.0.8
com.apple.driver.AppleIntelBDWGraphicsFramebuffer	10.1.2
com.apple.driver.AppleLPC	3.1
com.apple.iokit.BroadcomBluetoothHostControllerUSBTransport	4.4.3f4
com.apple.Dont_Steal_Mac_OS_X	7.0.0
com.apple.driver.AppleHV	1
com.apple.driver.AppleIntelSlowAdaptiveClocking	4.0.0
com.apple.driver.AppleCameraInterface	5.41.0
com.apple.driver.AppleSMCLMU	208
com.apple.driver.AppleBacklight	170.8.3
com.apple.driver.AppleMCCSControl	1.2.13
com.apple.iokit.SCSITaskUserClient	3.7.7
com.apple.driver.AppleUSBCardReader	3.7.1
com.apple.driver.AppleTopCaseHIDEventDriver	86
com.apple.AppleFSCompression.AppleFSCompressionTypeDataless	1.0.0d1
com.apple.AppleFSCompression.AppleFSCompressionTypeZlib	1.0.0
com.apple.BootCache	38
com.apple.iokit.IOAHCIBlockStorage	2.8.5
com.apple.driver.AppleAHCIPort	3.1.8
com.apple.driver.AirPort.Brcm4360	1020.17.1a1
com.apple.driver.AppleSmartBatteryManager	161.0.0
com.apple.driver.AppleACPIButtons	4.0
com.apple.driver.AppleRTC	2.0
com.apple.driver.AppleHPET	1.8
com.apple.driver.AppleSMBIOS	2.1
com.apple.driver.AppleACPIEC	4.0
com.apple.driver.AppleAPIC	1.7
com.apple.nke.applicationfirewall	163
com.apple.security.quarantine	3
com.apple.security.TMSafetyNet	8
com.apple.iokit.IOSCSIMultimediaCommandsDevice	3.7.7
com.apple.iokit.IOBDStorageFamily	1.8
com.apple.iokit.IODVDStorageFamily	1.8
com.apple.iokit.IOCDStorageFamily	1.8
com.apple.iokit.IOUSBUserClient	900.4.1
com.apple.kext.triggers	1.0
com.apple.driver.DspFuncLib	272.51.3
com.apple.kext.OSvKernDSPLib	525
com.apple.iokit.IOATAPIProtocolTransport	3.5.0
com.apple.iokit.IOATAFamily	2.5.3
com.apple.iokit.IOSurface	108.0.1
com.apple.AppleGraphicsDeviceControl	3.12.6
com.apple.iokit.IOAcceleratorFamily2	203.14
com.apple.driver.AppleHDAController	272.51.3
com.apple.iokit.IOHDAFamily	272.51.3
com.apple.iokit.IOAudioFamily	204.3
com.apple.vecLib.kext	1.2.0
com.apple.iokit.IOBluetoothHostControllerUSBTransport	4.4.3f4
com.apple.iokit.IOBluetoothFamily	4.4.3f4
com.apple.driver.CoreCaptureResponder	1
com.apple.iokit.IOSlowAdaptiveClockingFamily	1.0.0
com.apple.driver.X86PlatformPlugin	1.0.0
com.apple.driver.IOPlatformPluginFamily	6.0.0d7
com.apple.iokit.IOSerialFamily	11
com.apple.driver.AppleGraphicsControl	3.12.6
com.apple.driver.AppleBacklightExpert	1.1.0
com.apple.iokit.IONDRVSupport	2.4.1
com.apple.driver.AppleSMC	3.1.9
com.apple.driver.AppleSMBusController	1.0.14d1
com.apple.iokit.IOGraphicsFamily	2.4.1
com.apple.iokit.IOSCSIBlockCommandsDevice	3.7.7
com.apple.iokit.IOUSBMassStorageDriver	1.0.0
com.apple.iokit.IOSCSIArchitectureModelFamily	3.7.7
com.apple.driver.usb.AppleUSBHub	1.0.1
com.apple.driver.AppleMultitouchDriver	304.10
com.apple.driver.AppleHIDTransport	5
com.apple.driver.AppleHIDKeyboard	181
com.apple.driver.AppleHSSPIHIDDriver	41.7
com.apple.driver.CoreStorage	517.20.1
com.apple.iokit.IOAHCIFamily	2.8.1
com.apple.driver.AppleThunderboltDPInAdapter	4.1.3
com.apple.driver.AppleThunderboltDPAdapterFamily	4.1.3
com.apple.driver.AppleThunderboltPCIDownAdapter	2.0.2
com.apple.driver.AppleThunderboltNHI	4.0.4
com.apple.iokit.IOThunderboltFamily	5.1.0
com.apple.iokit.IO80211Family	1110.26
com.apple.driver.mDNSOffloadUserClient	1.0.1b8
com.apple.iokit.IONetworkingFamily	3.2
com.apple.driver.corecapture	1.0.4
com.apple.driver.AppleHSSPISupport	41.7
com.apple.driver.AppleIntelLpssSpiController	2.0.59
com.apple.driver.AppleIntelLpssGspi	2.0.59
com.apple.driver.usb.AppleUSBXHCIPCI	1.0.1
com.apple.driver.usb.AppleUSBXHCI	1.0.1
com.apple.driver.AppleIntelLpssDmac	2.0.59
com.apple.iokit.IOUSBFamily	900.4.1
com.apple.iokit.IOUSBHostFamily	1.0.1
com.apple.driver.AppleUSBHostMergeProperties	1.0.1
com.apple.driver.AppleEFINVRAM	2.0
com.apple.driver.AppleEFIRuntime	2.0
com.apple.iokit.IOHIDFamily	2.0.0
com.apple.iokit.IOSMBusFamily	1.1
com.apple.security.sandbox	300.0
com.apple.kext.AppleMatch	1.0.0d1
com.apple.driver.AppleKeyStore	2
com.apple.driver.AppleMobileFileIntegrity	1.0.5
com.apple.driver.AppleCredentialManager	1.0
com.apple.driver.DiskImages	417.1
com.apple.iokit.IOStorageFamily	2.1
com.apple.iokit.IOReportFamily	31
com.apple.driver.AppleFDEKeyStore	28.30
com.apple.driver.AppleACPIPlatform	4.0
com.apple.iokit.IOPCIFamily	2.9
com.apple.iokit.IOACPIFamily	1.4
com.apple.kec.Libm	1
com.apple.kec.pthread	1
com.apple.kec.corecrypto	1.0
Model: MacBookAir7,2, BootROM MBA71.0166.B09, 2 processors, Intel Core i7, 2.2 GHz, 8 GB, SMC 2.27f2
Graphics: Intel HD Graphics 6000, Intel HD Graphics 6000, Built-In
Memory Module: BANK 0/DIMM0, 4 GB, DDR3, 1600 MHz, 0x80AD, 0x483943434E4E4E384A544D4C41522D4E544D
Memory Module: BANK 1/DIMM0, 4 GB, DDR3, 1600 MHz, 0x80AD, 0x483943434E4E4E384A544D4C41522D4E544D
AirPort: spairport_wireless_card_type_airport_extreme (0x14E4, 0x117), Broadcom BCM43xx 1.0 (7.21.94.136.1a1)
Bluetooth: Version 4.4.3f4 16616, 3 services, 19 devices, 1 incoming serial ports
Network Service: Wi-Fi, AirPort, en0
Serial ATA Device: APPLE SSD SM0512G, 500.28 GB
USB Device: USB 3.0 Bus
USB Device: BRCM20702 Hub
USB Device: Bluetooth USB Host Controller
Thunderbolt Bus: MacBook Air, Apple Inc., 27.2