Created
January 1, 2024 06:32
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Converting a 5-day drug schedule to a matching weekly drug schedule
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import numpy as np | |
import pk | |
import seaborn as sns | |
drug = pk.Drug(hl=8, t_max=1) | |
# 5 day simulation | |
conc = drug.concentration( | |
60, | |
1, | |
doses={ | |
0: 100, | |
5: 100, | |
10: 100, | |
15: 100, | |
20: 100, | |
25: 100, | |
30: 100, | |
35: 100, | |
40: 100, | |
45: 100, | |
50: 100, | |
55: 100, | |
60: 100, | |
} | |
) | |
# Weekly simulation | |
weekly_conc = drug.concentration( | |
60, | |
1, | |
doses={ | |
0: 100, | |
7: 100, | |
14: 100, | |
21: 100, | |
28: 100, | |
35: 100, | |
42: 100, | |
49: 100, | |
56: 100, | |
63: 100, | |
} | |
) | |
sns.set_style("whitegrid") | |
sns.lineplot(x=range(0, conc.shape[0]), y=conc) | |
sns.lineplot(x=range(0, weekly_conc.shape[0]), y=weekly_conc) | |
# Now adjust the dosage to make them match | |
# 4 day simulation | |
new_conc = drug.concentration( | |
60, | |
1, | |
doses={ | |
0: 125, | |
7: 125, | |
14: 125, | |
21: 125, | |
28: 125, | |
35: 125, | |
42: 125, | |
49: 125, | |
56: 125, | |
63: 125, | |
} | |
) | |
sns.set_style("whitegrid") | |
sns.lineplot(x=range(0, conc.shape[0]), y=conc) | |
sns.lineplot(x=range(0, new_conc.shape[0]), y=new_conc) |
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