example my setup.py by Cx_freeze

setup.py

# python setup.py build

from cx_Freeze import setup, Executable
import sys
import os
import shutil
import zipfile


__appname__ = "userial-qt5"
__version__ = "0.9.0"
__icon__ = os.path.join(os.curdir, 'rc', 'logo.ico')
__author__ = "Aleksandr Smirnov"
__copyright__ = "Copyright 2016 by Navi-Dals"


BUILD_DIR = "exe.{}-{}".format(sys.platform, sys.version[:3])
path_build = os.path.join(os.curdir, "build", BUILD_DIR)


# Build executable file
build_exe_options = {"excludes": ["xml", "email", "html", "http", "unittest", "urllib",
                                  "pydoc_data", ""]}

exe = Executable(
    script="main.py",
    base="Win32GUI",
    targetName=__appname__ + ".exe",
    icon=__icon__
)

try:
    setup(
        name=__appname__ + ".exe",
        version=__version__,
        author=__author__,
        description=__copyright__,
        options={"build_exe": build_exe_options},
        executables=[exe]
    )
except Exception as e:
    print(e)

# Remove nonusble resource
print("Remove nonusble resource", end=10*'.')
try:
    path_rm = os.path.join(path_build, "PyQt5", "Qt")
    if os.path.exists(path_rm):
        shutil.rmtree(path_rm)
    print('Ok')
except Exception as e:
    print('Error')
    print(e)

# Create zip
print("Create zip file", end=10*'.')
try:
    def zipdir(path, ziph):
        for root, dirs, files in os.walk(path):
            for file in files:
                ziph.write(os.path.join(root, file))

    zip_name = '.'.join(['{}-{}'.format(__appname__, __version__), 'zip'])

    zipf = zipfile.ZipFile(zip_name, 'w', zipfile.ZIP_DEFLATED)
    zipdir(path_build, zipf)
    zipf.close()

    zip_dist = os.path.join(os.curdir, "zip")
    if not os.path.exists(zip_dist):
        os.makedirs(zip_dist)

    shutil.move(os.path.join(os.curdir, zip_name), os.path.join(zip_dist))

    print('Ok')
except Exception as e:
    print("Error")