gistfile1.py

from collections import namedtuple

def read_shifty_csv(f):
    cols = None
    for line in f:
        line = line.strip()
        if line.startswith('#'):
            cols = namedtuple('cols', line[1:].split(','))
        else:
            yield cols(*line.split(','))
f = open('test.csv')
import pprint
pprint.pprint(list(read_shifty_csv(f)))