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import gzip, random | |
# Load FASTQ file for Chromosome 10 from GRCm38 | |
with gzip.open("data/Mus_musculus.GRCm38.dna.chromosome.10.fa.gz") as f: | |
firstline = f.readline() | |
assert firstline.startswith(b'>') | |
chrom_seq = b"".join(l.rstrip() for l in f) | |
# This here is the file from papagei:mnt/raid/scnmt_data/CpG_filtered | |
cpg = scipy.sparse.load_npz( "data/CpG_10.npz" ).tocoo() | |
for i in range(100): | |
p = random.choice(cpg.row) | |
s = chrom_seq[ p-2 : p+3 ] | |
s = s.lower().replace( b"cg", b"CG" ) | |
print(s) |
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b'aCGga' | |
b'CGaca' | |
b'CGaga' | |
b'aCGct' | |
b'CGaca' | |
b'tCGag' | |
b'tCGtc' | |
b'CGttt' | |
b'CGact' | |
b'CGtgt' | |
b'CGtga' | |
b'tCGag' | |
b'aCGga' | |
b'aCGtg' | |
b'CGtga' | |
b'CGaag' | |
b'aCGga' | |
b'aCGct' | |
b'aCGgt' | |
b'CGtct' | |
b'aCGtt' | |
b'CGtcc' | |
b'CGtga' | |
b'CGtcc' | |
b'aCGtg' | |
b'tCGat' | |
b'tCGtc' | |
b'CGaaa' | |
b'aCGtg' | |
b'tCGga' | |
b'CGtaa' | |
b'CGacc' | |
b'tCGct' | |
b'tCGag' | |
b'CGtag' | |
b'CGtgg' | |
b'aCGcc' | |
b'tCGaa' | |
b'CGatg' | |
b'CGaca' | |
b'CGtag' | |
b'CGtgg' | |
b'CGacc' | |
b'tCGgc' | |
b'CGatg' | |
b'CGtta' | |
b'tCGta' | |
b'tCGtg' | |
b'CGtct' | |
b'tCGtt' | |
b'CGttc' | |
b'CGtgg' | |
b'CGatc' | |
b'aCGct' | |
b'CGaaa' | |
b'aCGta' | |
b'CGtgt' | |
b'tCGtc' | |
b'aCGgt' | |
b'aCGga' | |
b'CGttt' | |
b'CGtgc' | |
b'aCGtg' | |
b'aCGct' | |
b'CGacc' | |
b'CGata' | |
b'CGttt' | |
b'CGtat' | |
b'CGtgg' | |
b'aCGtg' | |
b'CGact' | |
b'CGagg' | |
b'CGaag' | |
b'aCGag' | |
b'CGagg' | |
b'CGtgg' | |
b'CGtaa' | |
b'CGtgt' | |
b'aCGta' | |
b'CGtct' | |
b'CGtct' | |
b'CGaat' | |
b'CGtgt' | |
b'tCGgg' | |
b'tCGct' | |
b'tCGaa' | |
b'CGttt' | |
b'CGatg' | |
b'tCGaa' | |
b'CGtat' | |
b'tCGtc' | |
b'aCGaa' | |
b'tCGga' | |
b'CGagc' | |
b'CGacc' | |
b'tCGag' | |
b'aCGta' | |
b'aCGtt' | |
b'aCGtg' | |
b'CGtat' |
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