Simple autoclicker. Dependencies in comment.

autoclicker.py

import pyautogui
import keyboard
import sys

# Change this to whatever shortcut you want
start_shortcut = 'alt+x'
stop_shortcut = 'esc'

def info():
    print(f'Press {start_shortcut} to start')
    print(f'Press {stop_shortcut} to stop.')

def on_pressed():
    running = True
    while running:
        pyautogui.click()
        # TODO: implement a way to control time between clicks
        if keyboard.is_pressed(stop_shortcut):
            running = False

info()
keyboard.add_hotkey(start_shortcut, on_pressed)
keyboard.wait()

It needs the following modules:
pip3 install pyautogui
pip3 install keyboard

To run it you first need to enter:
xhost + (not totally sure why though)
and then sudo python3 autoclicker.py (yes, with sudo).