stuff.js

doStuff().then(function(things) {
    if (!things) {
      throw new Error("Here I want to skip everything else, including the 'then's after the next catch..");
    }

    if (canMakeNewThing) {
      // This should continue to the next 'then'
      return someNewThing.save();
    }

    return doSomeOtherThingsFirst().then(function(hold) {
      return doMoreOtherThings(); // Should continue to the next 'then'
    }).catch(function(err) {
      throw new Error("This should skip the remaining thens as well..");
    });

  }, function(err) {
    throw new Error(); // Skip the next then.
  }).then(function() {

    req.flash('success', 'Reserved!');
    res.redirect('/blah');

  }, function(err) {
    console.log("Bailed.", err.stack);
    // Don't do any rendering here, this is where errors go.
  });

with-generators.js

var things = yield doStuff();

if (!things) {
    throw new Error("easy");
}

if (canMakeNewThing) {
    var newThing = yield someNewThing.save();
}

yield doSomeOtherThingsFirst();
yield doMoreOtherThings();

req.flash('success', 'Woot!');
res.redirect('/blah');