First, to set up Aemulus Package Manager, install these dependencies:
sudo pacman -S curl wine wine-mono winetricks p7zip unzip desktop-file-utils lib32-gnutls lib32-gst-plugins-base
or wine-staging if you prefer that.
For Aemulus, install .NET Desktop Runtime 8.0.11 (64-bit) and .NET Core Desktop Runtime 3.1.10 (64-bit) through wine
Launching Reloaded-II will prompt you to install missing dependencies by itself