Just npm install express mustache and you're up and running. Express works with stache (which includes mustache.js), though Google seems to insist the Mu library rank higher.
mustache doesn't support express natively, but stache is an up-to-date wrapper that supports layouts.
This really works for you?
I get only error TypeError: Object # has no method 'compile' at node_modules/express/lib/view.js:65:33.
Mustache object has no method compile.