To release OSX of a CDC device (like Arduino)
sudo kextunload -b com.apple.driver.AppleUSBCDCECMData
sudo kextunload -b com.apple.driver.AppleUSBCDCACMControl
sudo kextunload -b com.apple.driver.AppleUSBCDCACMData
sudo kextunload -b com.apple.driver.AppleUSBCDCWCM
sudo kextunload -b com.apple.driver.AppleUSBCDC
To list USB devices virtualbox can forward:
VBoxManage list usbhost