Exemplo com pyp5js: https://berinhard.github.io/pyp5js/pyodide/

pyodide-exemplo.py

from random import randint

def setup():
    createCanvas(500, 500)
    background(240, 240, 200)
    rectMode(CENTER)
    noFill()
    
    for k in range(5):
        for j in range(10):
            pos_y = j * 50
            
            for i in range(10):
                x = i * 50
                stroke(randint(100, 255), 128, randint(0, 128))
                tamanho = randint(20, 45)
                # translate(j / 2, i / 2)
                # angulo = randint(1, 2)
                # rotate(radians(angulo))
                
                ox, oy = randint(23, 27), randint(23, 27)
                rect(x + ox, pos_y + oy, tamanho, tamanho)