Amazon Music streams different tracks at different rates, many above the default bit rate that pipewire ships with.
This is how to fix it.
Firstly, I am running the Windows Amazon Music app via Crossover, a user-friendly version of wine.
It works, it's stable. Ubuntu 22.04.
Getting the app can annoying. Once you have the download file, keep it. The app automatically updates and amazingly this works in Linux too.
here are some tips: https://uk.amazonforum.com/s/question/0D56Q0000CMRC0dSQH/amazon-music-desktop-app-deletedmissing
Reduce CPU use: I get much, much lower CPU by turning on the DXVK Advanced Option in the Crossover Bottle setting, which keeps the PC fans almost silent for me. The app has an option to use Hardware Accelarated Rendering. I doubt this works on Linux, and it makes no difference. The app doesn't do much rendering while playing back, perhaps this is more for browsing.