Sample of Menu removing for Brackets.

main.js

define(function (require, exports, module) {
    'use strict';

    var CommandManager = brackets.getModule("command/CommandManager"),
        Menus          = brackets.getModule("command/Menus");

    
    // Function to run when the menu item is clicked
    function handleHelloWorld() {
        menu.removeMenuItem(MY_COMMAND_ID);
        window.alert("Hello, world!");
    }

    // Function to run when the menu item is clicked
    function handleHelloWorldContext() {
        contextMenu.removeMenuItem(MY_COMMAND_ID_CONTEXT);
        window.alert("Hello, world Context!");
    }
    
    
    // First, register a command - a UI-less object associating an id to a handler
    var MY_COMMAND_ID = "helloworld.sayhello";   // package-style naming to avoid collisions
    CommandManager.register("Hello World", MY_COMMAND_ID, handleHelloWorld);
     var MY_COMMAND_ID_CONTEXT = "helloworld.context.sayhello";   // package-style naming to avoid collisions
    CommandManager.register("Hello World Context", MY_COMMAND_ID_CONTEXT, handleHelloWorldContext);

    // Then create a menu item bound to the command
    // The label of the menu item is the name we gave the command (see above)
    var menu = Menus.getMenu(Menus.AppMenuBar.FILE_MENU);
    var contextMenu = Menus.getContextMenu("project-context-menu");

    contextMenu.addMenuItem(MY_COMMAND_ID_CONTEXT);
    menu.addMenuItem(MY_COMMAND_ID);
    
});