Details efforts I've taken to get U-20 Editor to work in Wine 5 (not successful so far)

U-20_Editor_on_Wine5_almost

setting up U20_Editor in WINE 5.x

These instructions assume an environment based on Ubuntu 18.x or 20.x; actual environment where this was tested was Modicia 20

# install Wine
sudo apt-get install wine-stable

# get the U20 Editor installer
https://web.archive.org/web/20191118133803/http://llamamusic.com/u20/U-20_220_Editor_v4.1.zip (works, and best link I've been able to find)

# create a 32-bit Wine prefix (I choose to aggregate my prefixes in ~/wine/)
mkdir -p ~/wine
WINEPREFIX="$HOME/wine/32bit" WINEARCH=win32 wine wineboot

# install U20 Editor in the 32-bit prefix (we assume the zip file is in ~/Downloads/)
unzip ~/Downloads/U-20_220_Editor_v4.1.zip
WINEPREFIX="$HOME/wine/32bit" wine ~/Downloads/U-20-220_Editor_setup41.exe
# provide the various mouse-clicks and choices to install the Windows app

# align Windows MIDI subsystem expectations with reality, ref. https://wiki.winehq.org/Wine_Developer%27s_Guide/Wine_and_Multimedia#Midi_mapper
# establish identifier for desired MIDI interface
aconnect -o
# identifiers from a Windows perspective will increment numerically for each identified interface, e.g.

mc3@mc3-macmini-vbox:$ aconnect -o
client 14: 'Midi Through' [type=kernel]
    0 'Midi Through Port-0'
client 20: 'mio' [type=kernel,card=1]
    0 'mio MIDI 1

# thus, Windows would see 'client 14' as '#0' and 'client 20' as '#1', illustrating the common problem outlined in the WineHQ link above

# construct an .INI file to feed to regedit (I put mine in the U20_Editor folder, just for consolidation)
vi ~/wine/32bit/drive_c/u20edit/REGEDIT4MIO.INI

REGEDIT4

[HKEY_CURRENT_USER\Software\Microsoft\Windows\CurrentVersion\Multimedia\MIDIMap]
"CurrentInstrument"="#1"

# feed the .INI file to regedit
WINEPREFIX="$HOME/wine/32bit" wine regedit.exe ~/wine/32bit/drive_c/u20edit/REGEDIT4MIO.INI

# assuming there aren't other issues causing the app to crash, U20EDIT should be usable at this point (in my testing, it continues to crash when I try to read the current patch after configuring the iConnectivity mio as both MIDI IN and MIDI OUT)