縦のノッチ一つ前提、ノッチの位置で安全マージンを設定する

NotchPadding.cs

using UnityEngine;

[ExecuteAlways]
public class NotchPadding : MonoBehaviour
{
    [SerializeField] RectTransform left, right;

    void Update()
    {
        if (Screen.cutouts == null || Screen.cutouts[0] == null || left == null || right == null)
            return;

        var resolition = Screen.currentResolution;

        left.anchorMin = new Vector2(0, Screen.cutouts[0].yMin / resolition.height);
        left.anchorMax = new Vector2(Screen.cutouts[0].xMin / resolition.width, 1);

        right.anchorMin = new Vector2(Screen.cutouts[0].xMax / resolition.width, Screen.cutouts[0].yMin / resolition.height);
        right.anchorMax = new Vector2(1, 1);
    }
}