Handling Keyboard Shortcuts in JavaScript http://www.openjs.com/scripts/events/keyboard_shortcuts/index.php

ShortcutsDemoPage.page

<apex:page showHeader="true" sidebar="false">
    <apex:includeScript value="{!$Resource.shortcut}" />
    <apex:form >
        <apex:outputText value="Ctrl+Shift+X Click!!" />
        <br/>
        <br/>
        <apex:outputText value="Ctrl+Shift+Y Click!!" />
        <br/>
        <br/>
        <apex:outputText value="Ctrl+Shift+Z Click!!" />
    </apex:form>
    <script>
        shortcut.add("Ctrl+Shift+X",function() {
            alert("Hi!! Ctrl+Shift+X Click!!");
        });
        shortcut.add("Ctrl+Shift+Y",function() {
            alert("Hi!! Ctrl+Shift+Y Click!!");
        });
        shortcut.add("Ctrl+Shift+Z",function() {
            alert("Hi!! Ctrl+Shift+Z Click!!");
        });
    </script>
</apex:page>