There are a few potential reasons for this error.
One is that the web server is not configured to allow outgoing connections on the port that the web scraper is trying to use (8443).
Another possibility is that the web scraper is trying to connect to a website that is blocking connections from the web server's IP address as part of an anti-scraping protection.
In that case you can try routing your requests through a proxy server.
Here's a example of using a proxy in your code:
import requests
s = requests.Session()
http_proxy = "http://0.0.0.0.0:0000"
https_proxy = "https://0.0.0.0.0:0000"
target = "http://taxsearch.co.grayson.tx.us:8443/"
headers = {} // your headers
proxies = {
"http": http_proxy,
"https": https_proxy,
}
r = s.get(url, headers=headers, proxies=proxies)