Generating QR code with image at the center.

qrcode_with_image.py

import pyqrcode
from PIL import Image

# create background - QR code
qr = pyqrcode.create('Some text',error = 'H')
qr.png('output.png', scale=10)

im = Image.open('output.png')
im = im.convert("RGBA")

# open image
logo = Image.open('logo.png')
# position of the image
box = (135,135,235,235)
im.crop(box)

region = logo
region = region.resize((box[2] - box[0], box[3] - box[1]), Image.ANTIALIAS)

# merging background and image
# passing image as a third parameter enables transparency
im.paste(region, box, region)
im.show()