di-in-requirejs.js

// EntryPoint.js
define(function () {
    return function EntryPoint(model1, model2) {
        // stuff
    };
});

// Model1.js
define(function () {
    return function Model1() {
        // stuff
    };
});

// Model2.js
define(function () {
    return function Model2(helper) {
        // stuff
    };
});

// Helper.js
define(function () {
    return function Helper() {
        // stuff
    };
});

// composition root, probably your main module
define(function (require) {
    var EntryPoint = require("./EntryPoint");
    var Model1 = require("./Model1");
    var Model2 = require("./Model2");
    var Helper = require("./Helper");

    var entryPoint = new EntryPoint(new Model1(), new Model2(new Helper()));
    entryPoint.start();
});