Created
March 25, 2024 10:51
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"instrumented" do_SingleR
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do_SingleRi = function(sce=NULL, path="/home/vincent/tenx3k.h5ad", | |
ref=celldex::HumanPrimaryCellAtlasData(), | |
ref.type = "label.main", | |
min.common = 1000, assay.type.test=1L, instrument=TRUE, | |
clprocid=NULL, ...) { | |
if (instrument == TRUE && is.null(clprocid)) stop("clprocid not set") | |
cl_timestamp(clprocid, "init") | |
stopifnot(ref.type %in% c("label.main", "label.fine")) | |
if (is.null(sce)) { | |
is_h5ad = length(grep("h5ad$", path)==1) | |
is_rda = length(grep("rda$", path)==1) | |
is_rds = length(grep("rds$", path)==1) | |
chk = sum(c(is_h5ad, is_rda, is_rds)) | |
if (chk != 1) stop("path must have suffix h5ad, rda or rds") | |
if (is_h5ad) sce = ingest_h5ad(path) | |
else if (is_rda) sce = get(load(path)) | |
else if (is_rds) sce = get(readRDS(path)) | |
stopifnot(inherits(sce, "SingleCellExperiment")) | |
} | |
cl_timestamp(clprocid, "pre-singler") | |
preds = SingleR(test=sce, | |
ref=ref, labels=ref[[ref.type]], assay.type.test=assay.type.test,...) | |
cl_timestamp(clprocid, "post-singler") | |
list(input=sce, preds=preds) | |
} |
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