config.ini

resources.Database.dsn = "mysql://root@localhost/treehousemb"
resources.Database.modelLoading = "conservative"
resources.Database.modelsPath = APPLICATION_PATH "/models"
resources.Database.cache.enabled = false
resources.Database.cache.servers.0.host = "localhost"
resources.Database.cache.servers.0.port = 11211
resources.Database.cache.servers.0.peristent = true
resources.Database.cache.queryCaching = false
resources.Database.cache.resultCaching = false
resources.Database.cache.defaultTTL = 360

Resource.php

require_once 'Zend/Application/Resource/ResourceAbstract.php';
/**
 * TODO: short description.
 * 
 * TODO: long description.
 * 
 */
class My_Resource_Database extends Zend_Application_Resource_ResourceAbstract
{
    
    /**
     * TODO: short description.
     * 
     * @return TODO
     */
    public function init()
    {
        $options = $this->getOptions();
        
        require_once 'Doctrine.php';
        require_once 'Doctrine/Manager.php';
        $manager = Doctrine_Manager::getInstance();
		$connection = $manager->connection( $options['dsn'] );
        
        if( $options['modelLoading'] == "conservative" ) {
            $manager->setAttribute( 
                Doctrine::ATTR_MODEL_LOADING, 
                Doctrine::MODEL_LOADING_CONSERVATIVE
            );
        }

		$manager->setAttribute('use_native_enum', true);
        $manager->setAttribute( Doctrine::ATTR_AUTOLOAD_TABLE_CLASSES, true );
	
        Doctrine::loadModels( $options['modelsPath'] );

		//------------------------------------------------------
		// Doctrine Caching
		//------------------------------------------------------
        
        if( $options['cache']['enabled'] ) {

            require_once 'Doctrine/Cache/Memcache.php';
		    $cacheDriver = new Doctrine_Cache_Memcache(array(
			    'servers' => $options['cache']['servers'],
                'compression' => false
		    ));
		    
            if ( $options['cache']['queryCaching'] ) {
		        $manager->setAttribute( Doctrine::ATTR_QUERY_CACHE, $cacheDriver );
		    }

		    if ( $options['cache']['resultCaching'] ) {
		        $manager->setAttribute( Doctrine::ATTR_RESULT_CACHE, $cacheDriver );
		    }

		    $manager->setAttribute(
		        Doctrine::ATTR_RESULT_CACHE_LIFESPAN,
		        $option['cache']['defaultTTL']
		    );
        }

        return $connection;
    }