Unfollow everyone on Twitter.

unfollow_everyone.py

#!/usr/bin/env python

import tweepy
from config import create_api


def unfollow_everyone(api):
    friends = api.friends_ids("<your_twitter_screen_name")

    for f in friends:
        print("Unfollowing {0}".format(api.get_user(f).screen_name))
        api.destroy_friendship(f)


def main():
    api = create_api()
    unfollow_everyone(api)


if __name__ == "__main__":
    main()