This function clones an element/node and thus removes all event listeners. Using the returned promise, you can then set new listeners on the element.

cloneNodeRemoveEvents.js

function cloneNodeRemoveEvents(el, withChildren) {
    if (withChildren) {
        el.parentNode.replaceChild(el.cloneNode(true), el);
    }
    else {
        var newEl = el.cloneNode(false);
        while (el.hasChildNodes()) newEl.appendChild(el.firstChild);
        el.parentNode.replaceChild(newEl, el);
    }

    return new Promise(function(resolve, reject) {
       resolve(newEl); 
    });
}