word_games.py

f = open("sowpods.txt", "r")
canonized_words = {}
word1 = ""
word2 = ""
max_len = 0

for line in f:
    if len(line) > max_len:
        sorted_word = ''.join(sorted(line))

        if sorted_word in canonized_words:
            found_word = canonized_words[sorted_word]
            word1 = line
            word2 = found_word
            max_len = len(word1)
        else:
            canonized_words[sorted_word] = line

print word1 + ", " + word2