wsgi.py

import plaster
import sys

def main():
    if '--reload' in sys.argv:
        import hupper
        reloader = hupper.start_reloader(__name__ + '.main')
        reloader.watch_files(['site.ini'])

    loader = plaster.get_loader('site.ini', protocols=['wsgi'])
    loader.setup_logging()
    server_runner = loader.get_wsgi_server()
    app = loader.get_wsgi_app()
    server_runner(app)

That's really succinct.